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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Envamine A 5mg/2.5mg Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Ramipril, which relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, thereby lowering blood pressure. It also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache and swelling of the ankles or feet. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Not Returnable

About Envamine A 5mg/2.5mg Tablet

Envamine A 5mg/2.5mg Tablet is used to treat hypertension (high blood pressure). Hypertension is a medical condition, in which the blood exerts high pressure (force exerted by circulating blood) against blood vessel's walls. This condition makes the heart work harder to pump blood into the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Envamine A 5mg/2.5mg Tablet contains Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor). Amlodipine is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain) and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood throughout the body and thereby lowering blood pressure. It also decreases the body’s production of certain substances that raise blood pressure.

Your doctor will advise you how often you take Envamine A 5mg/2.5mg Tablet based on your medical condition. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache and swelling of the ankles or feet. Most of these side effects of Envamine A 5mg/2.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Do not stop taking Envamine A 5mg/2.5mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Regular monitoring of blood pressure, electrolyte levels, and kidney function is advised while taking Envamine A 5mg/2.5mg Tablet. Inform your doctor if you are suffering from kidney, liver or heart diseases. Please tell your doctor if you are taking any other medicines or have any allergic reactions to Envamine A 5mg/2.5mg Tablet. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Envamine A 5mg/2.5mg Tablet. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Envamine A 5mg/2.5mg Tablet can be prescribed accordingly.

Uses of Envamine A 5mg/2.5mg Tablet

Treatment of Hypertension (high blood pressure).

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it. Try to take it at a fixed time every day. Do not double the dose if missed.

Medicinal Benefits

Envamine A 5mg/2.5mg Tablet consists of Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor). Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle so that it receives more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood throughout the body and thereby lowering blood pressure.

How Envamine A 5mg/2.5mg Tablet Works

Envamine A 5mg/2.5mg Tablet contains Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor). Amlodipine is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain) and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood throughout the body and thereby lowering blood pressure. It also decreases the body’s production of certain substances that raise blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Envamine A 5mg/2.5mg Tablet

  • Blurred vision
  • Sweating
  • Confusion
  • Tiredness
  • Stomach upset
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Dizziness
  • Headache
  • Swelling of the ankles or feet

What if I have taken an overdose of Envamine A 5mg/2.5mg Tablet

Do not take more than the prescribed dose of Envamine A 5mg/2.5mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Envamine A 5mg/2.5mg Tablet if you are allergic to Envamine A 5mg/2.5mg Tablet or any of its components. Please inform your doctor if you are using any prescription and non-prescription medications you are taking, including vitamins, before starting Envamine A 5mg/2.5mg Tablet. Let your doctor know if you have any history of severe heart, kidney or liver diseases, high potassium levels (hyperkalaemia), bone marrow suppression, and aortic stenosis (heart valve problem). Please consult your doctor if you plan to conceive, are pregnant, or are a breastfeeding mother before using Envamine A 5mg/2.5mg Tablet. Envamine A 5mg/2.5mg Tablet can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
RamiprilAliskiren
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Using Envamine A 5mg/2.5mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Envamine A 5mg/2.5mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
RamiprilAliskiren
Critical
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Taking aliskiren together with Envamine A 5mg/2.5mg Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Envamine A 5mg/2.5mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
AmlodipineSimvastatin
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Taking simvastatin with Envamine A 5mg/2.5mg Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Envamine A 5mg/2.5mg Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipinePrimidone
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Using Envamine A 5mg/2.5mg Tablet and primidone together may lower Envamine A 5mg/2.5mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Envamine A 5mg/2.5mg Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Co-administration of Tizanidine and Envamine A 5mg/2.5mg Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Envamine A 5mg/2.5mg Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Coadministration of lemborexant and Envamine A 5mg/2.5mg Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Envamine A 5mg/2.5mg Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Coadministration of Envamine A 5mg/2.5mg Tablet with itraconazole may significantly raise the blood levels and effects of Envamine A 5mg/2.5mg Tablet.

How to manage the interaction:
Envamine A 5mg/2.5mg Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineRifapentine
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Coadministration of Envamine A 5mg/2.5mg Tablet and Rifapentine may significantly reduce the blood levels of Envamine A 5mg/2.5mg Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Envamine A 5mg/2.5mg Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Using a combination of Envamine A 5mg/2.5mg Tablet and enzalutamide may drastically lower Envamine A 5mg/2.5mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Envamine A 5mg/2.5mg Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Envamine A 5mg/2.5mg Tablet:
Using Envamine A 5mg/2.5mg Tablet and mitotane together may drastically lower Envamine A 5mg/2.5mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Envamine A 5mg/2.5mg Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Envamine A 5mg/2.5mg Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Envamine A 5mg/2.5mg Tablet.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, use only one serving for women and two servings for men.

  • Quit smoking to lower the risk of heart diseases.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.

  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.

  • Try including heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Envamine A 5mg/2.5mg Tablet Substitute

Substitutes safety advice
  • Cardace AM 2.5 Tablet 15's

    by AYUR

    11.88per tablet
  • Ramistar-AM 2.5 mg/5 mg Tablet 15's

    by AYUR

    10.14per tablet
  • Ampine RL Tablet 10's

    by Others

    4.63per tablet
  • Amrevo R 5mg/2.5mg Tablet

    by Others

    5.85per tablet
  • Cardace AM 2.5 Tablet 10's

    by Others

    9.81per tablet
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Alcohol

Caution

Alcohol may lower your blood pressure. It would help if you avoided or limit consuming alcohol.

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Pregnancy

Caution

It is advised to seek medical advice before using Envamine A 5mg/2.5mg Tablet if you plan to conceive or a pregnant before using Envamine A 5mg/2.5mg Tablet.

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Breast Feeding

Caution

There are limited studies on how Envamine A 5mg/2.5mg Tablet affects breastfed infants. Please consult your doctor before using Envamine A 5mg/2.5mg Tablet if you are a lactating mother.

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Driving

Caution

Envamine A 5mg/2.5mg Tablet may cause side effects due to lowering of the blood pressure such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Envamine A 5mg/2.5mg Tablet. Envamine A 5mg/2.5mg Tablet is to be administered with caution in patients with severe hepatic impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Envamine A 5mg/2.5mg Tablet. Envamine A 5mg/2.5mg Tablet is primarily eliminated by the kidney and can be accumulated in patients with renal impairment.

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Children

Unsafe

Envamine A 5mg/2.5mg Tablet is not recommended for use in children as the efficacy and safety has not been established.

FAQs

Envamine A 5mg/2.5mg Tablet is used to treat hypertension (high blood pressure), a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessel's walls.

Envamine A 5mg/2.5mg Tablet consists of Amlodipine and Ramipril. Amlodipine relaxes blood vessels, so that blood passes through them easily thereby lowering the blood pressure. Ramipril relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body thereby lowering the raised blood pressure.

Envamine A 5mg/2.5mg Tablet is recommended to use in dose and duration as advised by the doctor. Do not stop taking Envamine A 5mg/2.5mg Tablet on your own as it may lead to a sudden rise in blood pressure increases the risk of heart attack and stroke.

Envamine A 5mg/2.5mg Tablet can cause dizziness as one of its side effects. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.

Amlodipine in Envamine A 5mg/2.5mg Tablet can cause ankle swelling upon long term use. Please try to keep your feet at the elevated position when sitting for long hours. If the problem persists, please consult your doctor and do as advised.

Envamine A 5mg/2.5mg Tablet may increase blood potassium levels in people with diabetes, poor kidney function and patients using potassium-sparing diuretics or taking potassium supplements. Please consult your doctor before taking Envamine A 5mg/2.5mg Tablet if you have diabetes.

Even though your blood pressure becomes normal after using Envamine A 5mg/2.5mg Tablet, it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Excessive alcohol consumption can lower blood pressure further and increase the risk of side effects. It's best to limit or avoid alcohol while taking this medication.

Common side effects of Envamine A 5mg/2.5mg Tablet may include blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache and swelling of the ankles or feet. Most of these side effects of Envamine A 5mg/2.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please contact your doctor.

Envamine A 5mg/2.5mg Tablet is generally not recommended for pregnant women. If you're pregnant or planning to become pregnant, discuss this with your doctor.

Your doctor will determine the appropriate dosage and frequency based on your needs. It's essential to follow the prescribed instructions.

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

No, stopping Amlodipine Ramipril suddenly can cause a sudden increase in blood pressure. Your doctor will gradually reduce your dosage to help prevent this.

Your doctor will schedule regular follow-up appointments to monitor your blood pressure and check for side effects. It's essential to attend these appointments.

Envamine A 5mg/2.5mg Tablet contains Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor).

If you are allergic to Envamine A 5mg/2.5mg Tablet, seek medical attention immediately. Symptoms may include hives, swelling of the face or throat, and difficulty breathing.

If you experience side effects from Envamine A 5mg/2.5mg Tablet, talk to your doctor. They may be able to adjust your dose or switch you to a different medication.

Manufacturer/Marketer address

Plot No. 276, Phase 2, Panchkula
Other Info - EN26243

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