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Epelar 300mg/300mg/400mg Tablet is used to treat HIV infection. It works by inhibiting enzymes which are necessary for the reproduction of the virus. In some cases, this medicine may cause side effects such as headache, dizziness, nausea, insomnia and fatigue. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Epelar 300mg/300mg/400mg Tablet

Epelar 300mg/300mg/400mg Tablet belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Epelar 300mg/300mg/400mg Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Epelar 300mg/300mg/400mg Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

You should take this medicine exactly as prescribed by the doctor. Epelar 300mg/300mg/400mg Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.

It is not recommended to take Epelar 300mg/300mg/400mg Tablet if you are allergic to any contents of it. Before taking Epelar 300mg/300mg/400mg Tablet, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, Hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Epelar 300mg/300mg/400mg Tablet should not be given to children below 2 years of age. Epelar 300mg/300mg/400mg Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Epelar 300mg/300mg/400mg Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Epelar 300mg/300mg/400mg Tablet

Epelar 300mg/300mg/400mg Tablet is used in the treatment of HIV infection. The detailed uses of Epelar 300mg/300mg/400mg Tablet are as follows:

  • Managing HIV-1 Infection: Epelar 300mg/300mg/400mg Tablet is used to treat individuals diagnosed with HIV-1. It includes Efavirenz, Lamivudine, and Tenofovir Disoproxil Fumarate, which work together to control the virus effectively in adults and children weighing 35 kg or more.
  • Inhibiting Viral Multiplication: Epelar 300mg/300mg/400mg Tablet helps stop the virus from multiplying by targeting the reverse transcriptase enzyme, a critical component in HIV’s replication cycle. This action reduces the amount of virus in the body and slows down disease progression.
  • Strengthening Immune Response: By reducing the viral load, Epelar 300mg/300mg/400mg Tablet contributes to an increase in CD4 cell counts, which are important for defending the body against infections. This leads to improved immune system performance.
  • Lowering the Risk of AIDS-related Complications: Consistent use of Epelar 300mg/300mg/400mg Tablet helps prevent the development of AIDS and decreases the likelihood of opportunistic infections such as pneumonia, tuberculosis, and certain cancers.

Key Benefits

Epelar 300mg/300mg/400mg Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Epelar 300mg/300mg/400mg Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

 

Directions for Use

  • Epelar 300mg/300mg/400mg Tablet should be taken on an empty stomach, or as prescribed by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Epelar 300mg/300mg/400mg Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Epelar 300mg/300mg/400mg Tablet Works

Epelar 300mg/300mg/400mg Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Epelar 300mg/300mg/400mg Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.
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Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects.

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Pregnancy

Caution

Epelar 300mg/300mg/400mg Tablet is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this Epelar 300mg/300mg/400mg Tablet.

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Breast Feeding

Caution

Epelar 300mg/300mg/400mg Tablet is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

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Driving

Caution

Epelar 300mg/300mg/400mg Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Epelar 300mg/300mg/400mg Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Epelar 300mg/300mg/400mg Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Epelar 300mg/300mg/400mg Tablet is not recommended for use in children below 2 years. In children above 2 years of age, dose adjustments may be necessary.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before taking Epelar 300mg/300mg/400mg Tablet. Your doctor will prescribe it only if the potential benefits outweigh the possible risks.

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Geriatrics

Caution

Epelar 300mg/300mg/400mg Tablet should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Epelar 300mg/300mg/400mg Tablet for geriatrics, please consult a doctor.

What if I have taken an overdose of Epelar 300mg/300mg/400mg Tablet

Take Epelar 300mg/300mg/400mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, trouble concentrating, sleepiness, unusual dreams, hallucination, uncontrolled muscle movements or shaking, and difficulty falling or staying asleep. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
  • Wash fruits and vegetables thoroughly. Use a separate cutting board for raw meats.
  • Wash hands, utensils, and cutting boards with soap and water after each use.
  • Eating a diet high in vegetables, fruits, whole grains, and legumes.
  • Choosing lean, low-fat sources of protein.
  • Limiting sweets, soft drinks, and foods with added sugar.
  • Including proteins, carbohydrates, and a little good fat in all meals and snacks.

Have a query?

How Soon It Starts Working

The time required for Epelar 300mg/300mg/400mg Tablet to start to work: Epelar 300mg/300mg/400mg Tablet ideally shows its action within few hours after administration. The time for which the effects of Epelar 300mg/300mg/400mg Tablet last: The effect of Epelar 300mg/300mg/400mg Tablet lasts for 24 hours.

What if you forget to take Epelar 300mg/300mg/400mg Tablet

If you miss a dose of Epelar 300mg/300mg/400mg Tablet, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep Epelar 300mg/300mg/400mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

It is not recommended to take Epelar 300mg/300mg/400mg Tablet if you are allergic to any contents of it. Before taking Epelar 300mg/300mg/400mg Tablet, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. Epelar 300mg/300mg/400mg Tablet should not be given to children below 2 years of age. Epelar 300mg/300mg/400mg Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. Epelar 300mg/300mg/400mg Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Epelar 300mg/300mg/400mg Tablet should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis.

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Drug-Drug Interactions:  Epelar 300mg/300mg/400mg Tablet may interact with drugs like anticancer (cisplatin), anti-depressant (citalopram), anti-fungal (fluconazole), antibiotics (gentamicin, ciprofloxacin, azithromycin, tobramycin), antimetabolites (methotrexate), potassium-sparing diuretics (amiodarone), anti-platelet drug (aspirin).

Drug-Food Interactions: Epelar 300mg/300mg/400mg Tablet may have interaction with St.John’s wort (herbal supplement used to treat depression). Avoid smoking and alcohol consumption while on this medication.

Drug-Disease Interactions: Epelar 300mg/300mg/400mg Tablet should not be used in patients with liver disease, kidney diseases, hepatitis B or C (liver infections), CNS disorders, heart diseases, hypercholesterolemia, bone disorders, lactic acidosis, immune reconstitution syndrome.

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Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Epelar 300mg/300mg/400mg Tablet is used to treat HIV infection.

Epelar 300mg/300mg/400mg Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Epelar 300mg/300mg/400mg Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

Epelar 300mg/300mg/400mg Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.

Epelar 300mg/300mg/400mg Tablet may cause the weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.

Epelar 300mg/300mg/400mg Tablet should not be stopped suddenly. Inform your doctor before stopping Epelar 300mg/300mg/400mg Tablet.

Epelar 300mg/300mg/400mg Tablet should be used with caution in liver diseases, kidney diseases, hypercholesterolemia, CNS disorders and lactic acidosis.

Disclaimer

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Country of origin

India
Other Info - EP12930
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