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Trilavir Mini Tablet is used to treat HIV infection. It works by inhibiting enzymes which are necessary for the reproduction of the virus. In some cases, this medicine may cause side effects such as headache, dizziness, nausea, insomnia and fatigue. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Laurus Labs Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Trilavir Mini Tablet

Trilavir Mini Tablet is a prescription medicine used to treat Human Immunodeficiency Virus type 1 (HIV-1) in adults and eligible pediatric patients. This medication works by keeping the viral load in your body as low as possible, which helps protect and support your immune system. It is not a cure for HIV, but it helps manage the condition and reduces the risk of developing serious complications.

To achieve the best results, you must take Trilavir Mini Tablet once every day, consistently at the exact same time. It is best taken on an empty stomach, ideally right before bedtime, as this helps minimise potential nervous system side effects. Adopting a balanced diet, staying hydrated, and engaging in moderate exercise can further support your overall immune health while on this therapy.

Some people may experience common side effects like dizziness, unusual dreams, headache, or trouble sleeping when starting this medication, which usually improve over time. However, you must consult your doctor immediately if you experience serious side effects such as severe skin rashes, persistent mood changes, or signs of liver problems.

Talk to your doctor before starting this medicine if you have pre-existing health conditions such as liver disease, kidney problems, or a history of mental health disorders. Do not take this if you have severe liver damage or certain heart rhythm abnormalities. Your healthcare provider will evaluate whether this treatment is safe for your specific health profile.

This medicine can interact with several other drugs, alcohol, and certain herbal supplements, which can either reduce its effectiveness or increase the risk of side effects. Avoid alcohol while taking this medication as it can strain your liver and worsen dizziness. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist to discuss the risks and benefits of using this medicine.

Uses of Trilavir Mini Tablet

Your doctor may prescribe this medicine to treat:

  • HIV-1 Infection: Helps control HIV-1 infection by reducing the amount of virus in the body, allowing the immune system to function more effectively. It is used as part of combination antiretroviral therapy and does not cure HIV infection.

Key Benefits

Trilavir Mini Tablet helps control HIV infection, improve immune function, and reduce the risk of HIV-related complications. Key benefits include:

  • Reduces Viral Load: Helps lower the amount of HIV in the blood, allowing the immune system to recover and function more effectively.
  • Supports Immune Health: By controlling viral replication, Trilavir Mini Tablet helps increase or maintain CD4 cell counts, reducing the risk of opportunistic infections and HIV-related illnesses.
  • Provides Convenient Once-Daily Combination Therapy: Combines three antiretroviral medicines into a single tablet, simplifying treatment and helping improve adherence to long-term HIV therapy.

Directions for Use

  • Trilavir Mini Tablet should be taken on an empty stomach, or as prescribed by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Trilavir Mini Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Trilavir Mini Tablet Works

Trilavir Mini Tablet contains efavirenz, lamivudine, and tenofovir disoproxil fumarate, which work together to prevent HIV from multiplying. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks the HIV reverse transcriptase enzyme, preventing the virus from making copies of its genetic material. Lamivudine and tenofovir disoproxil fumarate are nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs). They act as defective building blocks during viral DNA synthesis, causing premature termination of the viral DNA chain and preventing HIV from replicating. Together, these medicines reduce the amount of HIV in the body, helping protect the immune system and slow disease progression.
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Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects.

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Pregnancy

Caution

Trilavir Mini Tablet is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this Trilavir Mini Tablet.

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Breast Feeding

Caution

Trilavir Mini Tablet is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

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Driving

Caution

Trilavir Mini Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Trilavir Mini Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Trilavir Mini Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Trilavir Mini Tablet is not recommended for use in children below 2 years. In children above 2 years of age, dose adjustments may be necessary.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before taking Trilavir Mini Tablet. Your doctor will prescribe it only if the potential benefits outweigh the possible risks.

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Geriatrics

Caution

Trilavir Mini Tablet should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Trilavir Mini Tablet for geriatrics, please consult a doctor.

What if I have taken an overdose of Trilavir Mini Tablet

If you take more than your prescribed dose, seek emergency medical attention or contact a poison control centre immediately. An overdose can significantly increase your risk of severe nervous system side effects and liver damage.

Diet & Lifestyle Advise

  • Avoid high-fat meals around your dose: High-fat meals can increase the absorption of the efavirenz component, which may worsen dizziness, drowsiness, and other nervous system side effects.
  • Avoid alcohol: Alcohol can increase dizziness, drowsiness, and liver strain while taking Trilavir Mini Tablet.
  • Eat a balanced diet: Include plenty of fruits, vegetables, whole grains, and lean proteins to help support your immune system and overall health.
  • Stay well hydrated: Drink plenty of water throughout the day to support kidney function and maintain good hydration.
  • Take your medicine consistently: Take Trilavir Mini Tablet at the same time every day and do not miss doses, as consistent treatment helps keep the virus under control and reduces the risk of drug resistance.
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How Soon It Starts Working

The time required for Trilavir Mini Tablet to start to work: Trilavir Mini Tablet ideally shows its action within few hours after administration. The time for which the effects of Trilavir Mini Tablet last: The effect of Trilavir Mini Tablet lasts for 24 hours.

What if you forget to take Trilavir Mini Tablet

If you miss a dose, take it as soon as you remember, unless your next scheduled dose is less than 12 hours away. If your next dose is due in less than 12 hours, skip the missed dose and resume your regular bedtime schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Trilavir Mini Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medicine in its original container with the bottle tightly closed to protect it from light and moisture.

Drug Warnings

  • Take it at bedtime: Taking Trilavir Mini Tablet at bedtime may help reduce dizziness, drowsiness, and other nervous system side effects, particularly during the first few weeks of treatment.
  • Do not stop treatment without medical advice: Stopping Trilavir Mini Tablet suddenly or missing doses can increase the risk of HIV treatment failure and the development of drug resistance.
  • Attend regular check-ups: Your doctor may monitor your kidney function, liver function, viral load, and overall response to treatment through regular blood tests.
  • Use caution when driving: Trilavir Mini Tablet may cause dizziness, drowsiness, abnormal dreams, or difficulty concentrating. Avoid driving or operating machinery until you know how it affects you.
  • Tell your doctor if you have hepatitis B: If you have hepatitis B infection, do not stop taking Trilavir Mini Tablet without medical supervision, as this may cause a severe flare-up of hepatitis.

verifiedApollotooltip

Inform your doctor if you are using any of the following medicines, as they may interact with Trilavir Mini Tablet.

  • Medicines containing the same active ingredients: Do not take other medicines containing efavirenz, lamivudine, or tenofovir unless prescribed by your doctor.
  • Nephrotoxic medicines (such as certain NSAIDs or intravenous antivirals): May increase the risk of kidney damage, particularly due to the tenofovir component.
  • Medicines for tuberculosis, seizures, or hepatitis C: Some medicines (such as rifampicin, certain anticonvulsants, or some direct-acting antivirals) may reduce the effectiveness of Trilavir Mini Tablet or increase side effects.

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verifiedApollotooltip
  • High-fat meals: Avoid high-fat meals around the time of dosing, as they can increase efavirenz absorption and worsen nervous system side effects.
  • St. John's wort: Avoid herbal products containing St. John's wort, as they can reduce the effectiveness of Trilavir Mini Tablet and increase the risk of HIV drug resistance.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Trilavir Mini Tablet is used to treat HIV infection.
Trilavir Mini Tablet is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. Trilavir Mini Tablet also increases the CD4 cell (white blood cells that protect against infection) count in your blood.
Trilavir Mini Tablet may cause side-effects such as headache, dizziness, nausea, insomnia (difficulty in sleeping), weakness, depression, cough, diarrhoea, rash, impaired concentration, abnormal dreams, fatigue, nasal congestion (stuffy nose), pain. Inform your doctor if any of these side-effects persist or get worse.
Trilavir Mini Tablet should not be stopped suddenly. Inform your doctor before stopping Trilavir Mini Tablet.
Yes. One of the components of Trilavir Mini Tablet (tenofovir disoproxil fumarate) may reduce bone mineral density in some people, especially with long-term use. Your doctor may recommend regular monitoring, weight-bearing exercise, and calcium and vitamin D supplements if appropriate.
Trilavir Mini Tablet may not be suitable for everyone. Inform your doctor if you have liver disease, kidney disease, high cholesterol, central nervous system disorders, or a history of lactic acidosis before starting treatment. Your doctor will determine whether this medicine is appropriate for you.
No, it is best to take Trilavir Mini Tablet on an empty stomach, preferably at bedtime. Food, especially high-fat meals, can cause your body to absorb too much of the medicine too quickly, which increases the likelihood of side effects like dizziness and vivid dreams. Talk to your doctor or pharmacist if you struggle with this schedule.
Unusual or vivid dreams are a common side effect of the efavirenz component in Trilavir Mini Tablet. These side effects typically start during the first few weeks of treatment and usually improve over time. Taking your dose at bedtime on an empty stomach can help reduce these effects. Talk to your doctor if the dreams become severely disturbing.
No, Trilavir Mini Tablet does not cure HIV infection. It is a daily treatment that suppresses the virus to very low levels, helping your immune system stay healthy and reducing the risk of complications. You must continue taking it exactly as prescribed to keep the virus under control. Talk to your doctor for more information.
It is highly recommended to avoid or limit alcohol while taking Trilavir Mini Tablet. Both alcohol and this medicine are processed by the liver, and combining them increases the risk of liver damage and can make central nervous system side effects like dizziness and sleepiness much worse. Talk to your doctor or pharmacist about safe habits.
If you remember within 12 hours of your usual bedtime dose, take it immediately on an empty stomach. If your next dose is less than 12 hours away, skip the missed dose and take your next regular dose at your usual bedtime. Never take a double dose to make up for a missed one. Talk to your doctor if you frequently miss doses.
If you are pregnant, planning to become pregnant, or think you might be pregnant, you must discuss this with your doctor immediately. Some components of Trilavir Mini Tablet require careful consideration during pregnancy to ensure both your health and your baby's safety. Talk to your doctor to determine the best treatment options for you.
Signs of liver damage include yellowing of your skin or the whites of your eyes, dark or tea-colored urine, light-colored stools, persistent nausea, loss of appetite, or pain in the upper right side of your stomach. If you notice any of these symptoms, call your doctor right away. Talk to your doctor or pharmacist if you have concerns.
Some over-the-counter pain relievers, specifically NSAIDs like ibuprofen, can increase the strain on your kidneys when taken regularly with Trilavir Mini Tablet. It is always safest to ask a healthcare professional before taking any new medication. Talk to your doctor or pharmacist for a safe pain relief recommendation.

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