Epinorm Syrup 30 ml
MRP ₹40
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About Epinorm Syrup
Epinorm Syrup is primarily used in the prevention of vomiting and nausea. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response of the body to expel the stomach contents from the mouth forcefully.
Epinorm Syrup contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.
You may experience common side effects such as constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. If the side effects persist or worsen, please consult your doctor.
Before using Epinorm Syrup, inform your doctor if you are allergic to any of its ingredients. Epinorm Syrup should be used during pregnancy and breastfeeding only if prescribed by a doctor.
Uses of Epinorm Syrup
Epinorm Syrup is used in the prevention of Nausea and Vomiting. The detailed uses of Epinorm Syrup are as follows:
- Chemotherapy-Induced Nausea and Vomiting: Epinorm Syrup is frequently prescribed to alleviate nausea and vomiting caused by chemotherapy treatments.
- Radiation Therapy Support: Epinorm Syrup can help manage nausea and vomiting experienced by patients undergoing radiation therapy, improving treatment tolerance.
- Postoperative Nausea and Vomiting Relief: Many patients experience nausea or vomiting after surgical procedures, and Epinorm Syrup is effective in controlling and reducing these symptoms.
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Directions for Use
- Epinorm Syrup can be taken with or without food, as advised by the doctor.
- Typically, it is taken twice daily. However, follow your doctor's instructions on the dosage and timing of this medication.
- Swallow the tablet as a whole with a glass of water.
- Do not crush, chew, break, or open it.
Key Benefits
- Epinorm Syrup is an antiemetic medication primarily used to prevent and treat nausea and vomiting associated with conditions such as cancer chemotherapy, radiation treatment, and surgery.
- When serotonin levels increase in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain, which is responsible for controlling nausea and vomiting.
- Epinorm Syrup contains Ondansetron, which works by inhibiting the release of serotonin, thereby preventing nausea and vomiting.
How Epinorm Syrup Works
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- If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
- Inform your doctor about the medication you're taking and the symptoms you're experiencing.
- Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
- To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
- Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
- Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
- Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
- Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
- Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
- Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
- Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
- Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
- Omega-3 supplements may support the transport of oxygen to tissues.
- Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
- Quit smoking, as it can worsen hypoxia.
What if I have taken an overdose of Epinorm Syrup
Drug Warnings
- Do not use Epinorm Syrup if you are allergic to any of its ingredients.
- Avoid using Epinorm Syrup if you are taking apomorphine (a medicine used to treat Parkinson's disease), as it may cause a sharp drop in blood pressure and even fainting.
- Inform your doctor before using Epinorm Syrup if you have any medical conditions, such as severe constipation, bowel obstruction, depression, electrolyte imbalance, heart or blood vessel problems (such as irregular heartbeats and high blood pressure), diabetes, liver problems, or a history of tonsils or adenoid removal surgery.
- Tell your doctor if you are taking any medications for depression, as using them alongside Epinorm Syrup may increase the risk of serotonin syndrome, a potentially life-threatening condition.
- Epinorm Syrup is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.
- Avoid breastfeeding while taking Epinorm Syrup, as small amounts of the medicine may pass into breast milk.
- Avoid consuming alcohol while taking Epinorm Syrup, as it may worsen the side effects like drowsiness.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Epinorm Syrup 30 ml with Ziprasidone can increase the risk of abnormal heart rhythm.
How to manage the interaction:
Taking Epinorm Syrup 30 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Co-administration of Epinorm Syrup 30 ml with mifepristone can increase the risk of irregular heart rhythms.
How to manage the interaction:
Taking Epinorm Syrup 30 ml with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Coadministration of Epinorm Syrup 30 ml with Trazodone may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).
How to manage the interaction:
Although taking Epinorm Syrup 30 ml along with trazodone can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
When Epinorm Syrup 30 ml, is taken with tranylcypromine it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).
How to manage the interaction:
Although taking Epinorm Syrup 30 ml along with tranylcypromine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
Taking Epinorm Syrup 30 ml with hydroxychloroquine increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with hydroxychloroquine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
When Epinorm Syrup 30 ml is taken with doxepin, it can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in body).
How to manage the interaction:
Although taking Epinorm Syrup 30 ml along with doxepin can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
Using Epinorm Syrup 30 ml together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.
How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
Taking Epinorm Syrup 30 ml with nilotinib increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
Taking Epinorm Syrup 30 ml with ribociclib increases the risk of an abnormal heart rhythm.
How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with ribociclib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
Taking fentanyl with Epinorm Syrup 30 ml may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).
How to manage the interaction:
Although taking fentanyl with Epinorm Syrup 30 ml can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat small meals throughout the day and eat slowly to help digestion.
- If you are sensitive to food smells, try eating cold or room-temperature foods instead of hot ones.
- Avoid acidic foods or drinks like orange or grapefruit juice.
- After your meals, rest with your head elevated about 12 inches above your head.
- Drink liquids or water between meals rather than during meals.
- Eat when you are least nauseated to help prevent discomfort.
- Avoid consuming greasy or oily foods, as these foods can trigger nausea and vomiting.
- Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid makeup that has been lost due to vomiting.
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Alcohol
Safe if prescribed
Alcohol has no known direct interaction with Epinorm Syrup. However, it is advisable to avoid consuming alcohol while taking Epinorm Syrup, as it may worsen the side effects like drowsiness.
Pregnancy
Consult your doctor
Epinorm Syrup should be used during pregnancy only if prescribed by a doctor. It is generally not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.
Breast Feeding
Consult your doctor
Avoid breastfeeding while taking Epinorm Syrup, as small amounts of the medicine may pass into breast milk.
Driving
Safe if prescribed
Epinorm Syrup does not affect your ability to drive. However, if you experience drowsiness or blurred vision after taking Epinorm Syrup, avoid driving or operating any heavy machinery.
Liver
Consult your doctor
In individuals with liver problems, the use of Epinorm Syrup is allowed if prescribed by a doctor. However, patients with severe liver impairment should take a low dose of Epinorm Syrup as much as possible. Do not take more than 8 mg of Epinorm Syrup per day in case of liver disease.
Kidney
Consult your doctor
The use of Epinorm Syrup is considered safe in patients with kidney disorders. No dose adjustment is required.
Children
Safe if prescribed
Epinorm Syrup should not be given to children below 4 years of age, as its safety and effectiveness have not been established in this age group. The use of Epinorm Syrup is safe in children above 4 years of age if prescribed by a doctor.
Heart
Epinorm Syrup should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Epinorm Syrup.
Geriatrics
Consult your doctor
Epinorm Syrup should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Epinorm Syrup.
FAQs
Epinorm Syrup is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment, or surgery.
Epinorm Syrup contains Ondansetron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.
Epinorm Syrup may cause drowsiness and changes in vision, so avoid driving or operating any machines that require mental alertness.
People with an irregular heartbeat (arrhythmia) and phenylketonuria (too much of the protein phenylalanine in the blood) should not take Epinorm Syrup as it may cause serious conditions. The patient with liver disease should not take more than 8 mg of Epinorm Syrup daily. Taking Epinorm Syrup with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.
Epinorm Syrup contains Ondansetron, an antiemetic drug, used in the prevention of vomiting and nausea.
Epinorm Syrup is ineffective in preventing nausea associated with motion sickness.
Before taking Epinorm Syrup, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Also, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Epinorm Syrup usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.
Common side effects of Epinorm Syrup may include constipation, headache, diarrhea, drowsiness, flushing (a feeling of warmth), weakness, and tiredness. However, not every person experiences these side effects, and some of the unpleasant effects of Epinorm Syrup do not require medical attention. If the side effects persist or worsen, please consult your doctor.
Epinorm Syrup was not found to be beneficial in the treatment of seasickness.
Epinorm Syrup works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Epinorm Syrup prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy, or motion sickness.
Yes, you can take Epinorm Syrup half an hour to 1 hour before meals.
If you forget to take a dose of Epinorm Syrup, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and take your regular dose. Never take a double dose to make up for a forgotten dose.
If you take more than the recommended dose of Epinorm Syrup, it may result in an overdose. Signs and symptoms of an overdose of Epinorm Syrup may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.
No, Epinorm Syrup is not a steroid. Epinorm Syrup belongs to a class of drugs known as antiemetics.
While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.
Take Epinorm Syrup exactly as prescribed by the doctor. Take it at the same time daily, as it will help you remember to take the medication.
Yes, Epinorm Syrup can be given during pregnancy if prescribed by a doctor. However, it is not recommended for use during early pregnancy (first trimester), as it may increase the risk of birth defects in the mouth and face of the baby.
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Reference
- https://pdf.hres.ca/dpd_pm/00068458.PDF
- https://assets.hpra.ie/products/Human/20212/1c456dc8-a1c3-4bbd-a64e-bf71394c3935.pdf
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020103s035_020605s019_020781s019lbl.pdf
- https://www.medicines.org.uk/emc/product/10160/smpc
- https://www.drugs.com/ondansetron.html
- https://medlineplus.gov/druginfo/meds/a601209.html
