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compositionComposition:SODIUM VALPROATE-200MG
prescriptionPrescription Medicine
Epival Syrup 200 ml
Epival Syrup 200 ml

Epival Syrup is used to treat epilepsy and helps control different types of seizures or fits. It reduces the frequency and severity of seizure episodes and supports long-term seizure management, improving overall quality of life. Additionally, Epival Syrup is used in the treatment of bipolar disorder, where it helps stabilise mood, reduce episodes of mania, and control mood swings.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SODIUM VALPROATE-200MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Epival Syrup

Epival Syrup is used to treat epilepsy/seizures/fits. Additionally, Epival Syrup is also used to treat bipolar disorder. Epilepsy is a sudden rush of electricity in the brain.

Epival Syrup contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. This helps in controlling seizures.

Epival Syrup may cause side effects such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, and headache. Most of these side effects do not require medical attention. However, if the side effects persist, inform your doctor immediately.

Before using Epival Syrup , inform your doctor about your children's medical conditions, sensitivities, and all medications used. Epival Syrup should be gradually withdrawn; please do not discontinue Epival Syrup without consulting your physician. Consult your doctor immediately if you observe any suicidal tendencies in your children.

Uses of Epival Syrup

Epival Syrup is used to effectively manage neurological and mood disorders. The detailed uses of Epival Syrup are as follows:

  • Treats epilepsy: Epival Syrup helps control and reduce the frequency of seizures (fits).
  • Manages bipolar disorder: Epival Syrup stabilises mood swings and helps prevent episodes of mania and depression.

Have a query?

Directions for Use

  • Epival Syrup can be administered with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe.
  • Shake well before use.

Key Benefits

When used as prescribed, Epival Syrup may offer the following benefits

For Epilepsy:

  • Regulates a variety of seizure types, such as absence, focal, and generalised seizures.
  • Reduces the frequency and intensity of seizures by stabilising aberrant electrical activity in the brain.
  • Beneficial either alone or in conjunction with other antiepileptic medications.

For Bipolar disorder:

  • Stabilises mood, which aids in the management of acute manic episodes.
  • Reduce mood fluctuations and stop manic relapses.
  • Helpful for patients who don't react well to lithium.
  • Reduces impulsive behaviour, agitation, and irritation.

How Epival Syrup Works

Epival Syrup contains 'Sodium valproate' as active ingredient. • For seizures, it decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. • For Bipolar disorder, it increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Epival Syrup

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Epival Syrup may include breathing problems, feeling confused or changes to your normal behaviour, feeling or being sick (nausea or vomiting), headaches or feeling dizzy, muscle weakness, and passing out. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

  • Before using Epival Syrup , let your doctor know about all your children's medical conditions, sensitivities, and all medications used.
  • Do not use this medication if your child is allergic to any of its components.
  • Do not exceed the stated recommended dose.

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateBuprenorphine
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Epival Syrup 200 ml:
Combining Sodium phenylbutyrate and Epival Syrup 200 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Epival Syrup 200 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Epival Syrup 200 ml:
Using buprenorphine together with Epival Syrup 200 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Epival Syrup 200 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Epival Syrup 200 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Epival Syrup 200 ml:
The combined use of Ertapenem and Epival Syrup 200 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Leflunomide and Epival Syrup 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Epival Syrup 200 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Lithium with Epival Syrup 200 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Epival Syrup 200 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Ketamine and Epival Syrup 200 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Epival Syrup 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Vorinostat with Epival Syrup 200 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Meropenam and Epival Syrup 200 ml together can reduce the effect of Epival Syrup 200 ml.

How to manage the interaction:
Co-administration of Meropenam and Epival Syrup 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Teriflunomide and Epival Syrup 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Healthy eating habits:

  • To promote growth and development, serve a well-balanced meal rich in fruits, vegetables, whole grains, and enough protein.
  • To lower the risk of weight gain and liver stress, cut down on junk, fried, and fatty foods.
  • To keep your energy levels steady, make sure you eat frequent meals and wholesome snacks.

Lifestyle changes:

  • Keep a regular sleep schedule because sleep deprivation can cause seizures.
  • Promote safe physical activity and steer clear of circumstances that raise the risk of damage during seizures.

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

All Substitutes & Brand Comparisons

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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Consult your doctor

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Epival Syrup can be given safely to children. Give this medicine to your child in the doses as prescribed by the doctor.

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Heart

Caution

Epival Syrup is generally safe for children, but caution is needed if they have heart problems. Always consult a paediatrician before use to ensure it’s appropriate for your child’s condition and medications.

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Geriatrics

Not applicable

Epival Syrup is specifically for children's use and is not meant for geriatric patients.

FAQs

Epival Syrup is used to treat epilepsy/seizures/fits and bipolar disorder.

Epival Syrup decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.

Epival Syrup helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Do not discontinue Epival Syrup without consulting your doctor. To treat your child's condition effectively, continue using Epival Syrup for as long as prescribed. Do not be reluctant to speak with your doctor if your child experiences difficulty while taking Epival Syrup ; your doctor will gradually reduce the dose to avoid worsening seizures.

Epival Syrup may change the results of liver enzymes, urine, and blood tests. Inform the person doing the tests that your child is using Epival Syrup .

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - EPI0011

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