Epledart-25 Tablet 10's
MRP ₹220
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About Epledart-25 Tablet
Epledart-25 Tablet is used to treat your heart failure. It reduces the risk of death or the need for hospitalisation due to heart failure. Besides this, Epledart-25 Tablet is also used to treat high blood pressure.
Epledart-25 Tablet contains Eplerenone, which works by blocking the action of aldosterone, a natural substance that raises blood pressure. It also slows the progression of heart failure by reducing heart damage.
In some cases, Epledart-25 Tablet may cause side effects like nausea, vomiting, dizziness, diarrhoea, and elevated potassium levels. Most of these side effects of Epledart-25 Tablet do not require medical attention and resolve over time. However, if the side effects are persistent, reach out to your doctor.
Do not take Epledart-25 Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your medical conditions and medicines to prevent any potential interactions.
Uses of Epledart-25 Tablet
Epledart-25 Tablet is used to treat heart failure and high blood pressure. The detailed uses of Epledart-25 Tablet are as follows:
- Treatment of heart failure: Epledart-25 Tablet is indicated for patients with heart failure following a recent heart attack. It helps improve heart function, reduce symptoms, and lower the risk of hospitalisation and death due to heart-related complications.
- Management of high blood pressure: Epledart-25 Tablet is also prescribed to lower elevated blood pressure, either alone or in combination with other antihypertensive medications.
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Directions for Use
- Epledart-25 Tablet can be taken with or without food.
- Follow your doctor's instructions regarding the dosage and duration for effective results.
- Swallow it as a whole with a glass of water.
- Do not crush, chew, or break it.
Key Benefits
- Epledart-25 Tablet contains Eplerenone, an aldosterone antagonist that helps improve heart function and control blood pressure.
- Epledart-25 Tablet is beneficial for stable patients with left ventricular systolic dysfunction and congestive heart failure following an acute myocardial infarction (heart attack).
- It improves survival after a heart attack and helps reduce the risk of cardiovascular death and hospitalisation.
- Epledart-25 Tablet is used in patients with mild but persistent heart failure symptoms, especially when previous treatments are insufficient.
- Epledart-25 Tablet effectively lowers elevated blood pressure, which in turn reduces the risk of serious cardiovascular events such as stroke, heart attack (myocardial infarction), and heart failure.
- By blocking aldosterone (a hormone that can worsen heart failure and increase blood pressure), Epledart-25 Tablet helps treat heart failure and high blood pressure.
How Epledart-25 Tablet Works
Storage
- Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
- Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
- Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
- Limit dairy products to 200g of yoghurt or 300ml of milk per day.
- Increased creatinine levels must be corrected immediately with the help of a doctor.
- Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
- Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
- Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
- Avoid smoking and drinking alcohol.
- Talk to your doctor about oral potassium supplements.
- Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
- Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
- Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
- Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
- Limit dairy products to 200g of yoghurt or 300ml of milk per day.
What if I have taken an overdose of Epledart-25 Tablet
Drug Warnings
- Do not take Epledart-25 Tablet if you are allergic to any of its components, have severe liver or kidney disease, or high levels of potassium.
- Inform your doctor if you have kidney or liver disease, fungal infection, depression, HIV infection, bacterial infection or if you are taking immunosuppressants, or lithium (used to treat manic disorders).
- Consult your doctor if you are pregnant or breastfeeding.
- Epledart-25 Tablet is not recommended for children as the safety and effectiveness have not been established.
- Let your doctor know if you are taking any other medicines, including supplements and herbal products.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Epledart-25 Tablet and Ritonavir may significantly increase the blood levels of Epledart-25 Tablet.
How to manage the interaction:
Taking Ritonavir and Epledart-25 Tablet together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Epledart-25 Tablet and Clarithromycin may significantly increase the blood levels and effects of Epledart-25 Tablet.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.
How to manage the interaction:
Taking Clarithromycin with Epledart-25 Tablet is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
Coadministration of posaconazole with Epledart-25 Tablet can increase the blood levels of Epledart-25 Tablet. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).
How to manage the interaction:
Although there is an interaction between posaconazole and Epledart-25 Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of EPELENONE and SAQUINAVIR may significantly increase the blood levels and side effects of Epledart-25 Tablet. This can increase the risk of serious side effects like high blood potassium, which in severe cases can lead to kidney failure, muscle paralysis (loss of muscle function) and irregular heart rhythm.
How to manage the interaction:
Taking saquinavir and Epledart-25 Tablet together is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the doctor's advice.
Combining Epledart-25 Tablet with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.
How to manage the interaction:
Although there is a possible interaction between spironolactone and Epledart-25 Tablet, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Coadministration of Ketoconazole with Epledart-25 Tablet can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.
How to manage the interaction:
Taking ketoconazole with Epledart-25 Tablet is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
Coadministration of Nefazodone with Epledart-25 Tablet can increase the levels of Epledart-25 Tablet in the body.
How to manage the interaction:
Taking Nefazodone with Epledart-25 Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Epledart-25 Tablet with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.
How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Epledart-25 Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
The blood levels and effects of Epledart-25 Tablet may be greatly increased when combined with itraconazole.
How to manage the interaction:
Although there is a possible interaction between Epledart-25 Tablet and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
Using Epledart-25 Tablet together with Potassium chloride may significantly increase potassium levels in the blood.
How to manage the interaction:
Taking potassium chloride with Epledart-25 Tablet is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Consume antioxidant-rich foods such as blueberries, cherries, tomatoes, squash, and bell peppers.
- Use healthy cooking oils like soybean, olive, canola, and coconut oil.
- You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
- Reduce or eliminate trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
- Avoid the consumption of too much salt or salty food.
- Maintain a healthy weight with a BMI of 19.5-24.9.
- Regular physical activity or exercise, like walking, improves your blood flow.
- Avoid standing or sitting for extended periods.
- Avoid chronic stress, as it can raise your blood pressure.
- Spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.
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Alcohol
Safe if prescribed
You are recommended not to consume alcohol along with Epledart-25 Tablet to avoid unpleasant side effects.
Pregnancy
Consult your doctor
Epledart-25 Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult your doctor if you are pregnant.
Breast Feeding
Consult your doctor
Please consult your doctor if you are breastfeeding. It should be used only if prescribed by a doctor and if the benefits outweigh the harms.
Driving
Safe if prescribed
Epledart-25 Tablet may cause dizziness. Dro not drive or operate machinery unless you are alert.
Liver
Consult your doctor
Epledart-25 Tablet is not recommended for people with severe liver disease. Inform your doctor before starting Epledart-25 Tablet if you have a history of liver diseases/conditions.
Kidney
Consult your doctor
Epledart-25 Tablet is not recommended for people with severe kidney disease. Inform your doctor before starting Epledart-25 Tablet if you have a history of kidney diseases/conditions.
Children
Safe if prescribed
Epledart-25 Tablet is not recommended for children below 12 years of age.
Heart
Epledart-25 Tablet can be safely used in cardiac patients with hypertension if prescribed by a physician. Please consult your physician if you have any concerns.
Geriatrics
Consult your doctor
Epledart-25 Tablet should be used under caution in elderly patients. Close monitoring of potassium levels and kidney function is important.
FAQs
Epledart-25 Tablet is used to treat heart failure and hypertension (high blood pressure).
Epledart-25 Tablet contains Eplerenone, which works by blocking the action of aldosterone, a natural substance that raises blood pressure. It also slows the progression of heart failure by reducing heart damage.
Yes, Epledart-25 Tablet can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or if you are taking potassium supplements along with Epledart-25 Tablet . Please monitor your electrolyte level regularly to avoid increased blood potassium levels. Consult your doctor if you experience muscle cramps, diarrhoea, nausea, dizziness or headache.
No, Epledart-25 Tablet is not a blood thinner. It is a selective aldosterone blocker used to treat heart failure and high blood pressure.
Epledart-25 Tablet contains Eplerenone. It is an aldosterone antagonist type of potassium-sparing diuretic.
Epledart-25 Tablet may take up to 4 weeks to show its full effect. Keep taking Epledart-25 Tablet for the prescribed duration.
No, Epledart-25 Tablet is not known to cause erectile dysfunction. It does not have any effect on fertility.
Do not discontinue Epledart-25 Tablet without consulting the doctor. To treat your condition effectively, keep taking Epledart-25 Tablet for the prescribed duration.
Potassium-sparing diuretics increase urine production without depleting potassium reserves. Epledart-25 Tablet permits the body to lose sodium while retaining potassium. The amount of potassium may rise as a result. Therefore, your doctor may regularly check your potassium levels.
Your doctor might have recommended Eplerenone instead of Losartan as a blood pressure medication because losartan may have been insufficient in lowering your blood pressure. However, Eplerenone increases the risk of elevated potassium levels, which may not be suitable for you. Hence, the doctor has prescribed Epledart-25 Tablet along with hydrochlorothiazide to prevent the rise in potassium levels.
Before starting Epledart-25 Tablet , let the doctor know if you are taking aspirin. Taking aspirin with Epledart-25 Tablet may decrease the effects of Epledart-25 Tablet . Contact your doctor if you experience signs of high blood pressure such as headache, blurred vision, trouble concentrating, or dizziness.
Epledart-25 Tablet may cause side effects like nausea, vomiting, dizziness, diarrhoea, and elevated potassium levels. Most of these side effects of Epledart-25 Tablet do not require medical attention and resolve over time. However, if the side effects are persistent, reach out to your doctor.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021437s013lbl.pdf
- https://www.nps.org.au/assets/medicines/0ebbd413-7e5c-40cc-897d-a77600780bee-reduced.pdf
- https://medlineplus.gov/druginfo/meds/a603004.html
- https://www.drugs.com/mtm/eplerenone.html
- https://www.medicines.org.uk/emc/product/9207/pil
