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compositionComposition:EPLERENONE-25MG
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Prescription Medicine
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Eplerender-25 mg Tablet 10's is used to treat heart failure and high blood pressure. This medicine contains Eplerenone, which works by blocking the action of aldosterone and slowing the progression of heart failure, while also lowering blood pressure. In some cases, you may experience nausea, vomiting, dizziness, diarrhoea, and elevated potassium levels. Before starting Eplerender-25 mg Tablet 10's, inform the doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

EPLERENONE-25MG

Manufacturer/Marketer :

Elder Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Eplerender-25 mg Tablet 10's

Eplerender-25 mg Tablet 10's is a prescription medicine used to treat high blood pressure and to help protect the heart after a heart attack. It belongs to a group of medications that help block a hormone in your body that causes salt and water retention. By doing so, it helps lower your blood pressure and reduces the workload on your heart.

To get the best results, you should take Eplerender-25 mg Tablet 10's regularly at the same time every day as prescribed by your doctor. You can take this tablet with or without food. Combining this treatment with lifestyle changes, such as eating a low-salt diet and staying physically active, can significantly improve your cardiovascular health.

While taking Eplerender-25 mg Tablet 10's, you may experience mild side effects like dizziness, headache, or mild stomach upset. However, it can sometimes cause your body to hold onto too much potassium, which is a serious condition. If you experience muscle weakness, an irregular heart rate, or severe numbness, contact your doctor immediately.

Do not take this medicine if you have severe kidney disease, high levels of potassium in your blood, or if you are taking other potassium-sparing water pills. You should talk to your doctor before starting Eplerender-25 mg Tablet 10's if you have diabetes, mild-to-moderate kidney problems, or liver damage.

Let your healthcare provider know about all other medications you take, as certain pain relievers, heart medications, and alcohol can interact with Eplerender-25 mg Tablet 10's and affect your kidney function or blood pressure. Pregnant or breastfeeding women, as well as elderly individuals, should consult their doctor before starting this medication to ensure it is safe for them.

Uses of Eplerender-25 mg Tablet 10's

Eplerender-25 mg Tablet 10's is used to treat heart failure and high blood pressure. The detailed uses of Eplerender-25 mg Tablet 10's are as follows:

  • Heart failure after a heart attack: Helps improve survival rates and reduces the risk of hospitalization by easing the strain on the heart muscle.
  • High blood pressure (hypertension): Lowers blood pressure, which helps prevent future strokes, heart attacks, and kidney problems.

Key Benefits

Eplerender-25 mg Tablet 10's helps improve cardiovascular health by reducing the effects of excess fluid retention and lowering strain on the heart. It also helps control blood pressure, supporting better heart function and long-term protection of vital organs. Benefits may include:

  • Helps lower and maintain healthy blood pressure levels.
  • Reduces strain on the heart and supports improved heart function.
  • Helps relieve symptoms such as fatigue and shortness of breath associated with heart failure.
  • Reduces excess fluid retention and related discomfort.
  • Helps protect the kidneys, brain, and blood vessels from damage caused by high blood pressure.
  • May reduce the risk of serious cardiovascular complications and hospitalisation.
Side effects of Eplerender-25 mg Tablet
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.

Directions for Use

To ensure you take this medicine safely and effectively, follow these step-by-step instructions:

  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
  • You can take this medicine with or without food, but try to be consistent with how you take it.
  • Take your dose at the same time every day to help keep a steady amount of the medicine in your body.

Always follow your doctor's exact instructions regarding how much and how often to take this medicine. Do not change your dose without consulting your healthcare provider first.

How Eplerender-25 mg Tablet 10's Works

This medicine works by blocking the action of a naturally occurring hormone in your body called aldosterone. Aldosterone tells your kidneys to hold onto sodium (salt) and water while getting rid of potassium. By blocking this hormone, Eplerender-25 mg Tablet 10's helps your body flush out extra salt and water through urine, which lowers blood pressure and reduces the amount of work your heart has to do to pump blood. At the same time, it helps your body retain potassium, maintaining a proper balance of essential minerals.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Eplerender-25 mg Tablet 10's to avoid unpleasant side effects.

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Pregnancy

Caution

Eplerender-25 mg Tablet 10's should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult your doctor if you are pregnant.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. It should be used only if prescribed by a doctor and if the benefits outweigh the harms.

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Driving

Caution

Eplerender-25 mg Tablet 10's may cause dizziness. Dro not drive or operate machinery unless you are alert.

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Liver

Caution

Eplerender-25 mg Tablet 10's is not recommended for people with severe liver disease. Inform your doctor before starting Eplerender-25 mg Tablet 10's if you have a history of liver diseases/conditions.

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Kidney

Caution

Eplerender-25 mg Tablet 10's is not recommended for people with severe kidney disease. Inform your doctor before starting Eplerender-25 mg Tablet 10's if you have a history of kidney diseases/conditions.

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Children

Caution

Eplerender-25 mg Tablet 10's is not recommended for children below 12 years of age.

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Heart

Safe if prescribed

Eplerender-25 mg Tablet 10's can be safely used in cardiac patients with hypertension if prescribed by a physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Eplerender-25 mg Tablet 10's should be used under caution in elderly patients. Close monitoring of potassium levels and kidney function is important.

What if I have taken an overdose of Eplerender-25 mg Tablet 10's

If you take too much of this medicine, you may experience severe dizziness, weakness, or an irregular heartbeat. Seek immediate emergency medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Avoid potassium-containing salt substitutes: Do not use salt substitutes that contain potassium, as they may increase the risk of dangerously high potassium levels when taken with this medicine.
  • Be mindful of high-potassium foods: Limit foods rich in potassium, such as bananas, oranges, and leafy green vegetables, unless your doctor has advised otherwise.
  • Monitor your blood pressure: Check your blood pressure regularly at home and maintain a record to share with your healthcare provider during follow-up visits.
  • Stay properly hydrated: Drink fluids as recommended by your doctor, especially if you have heart failure or other conditions that require careful fluid management.

Have a query?

How Soon It Starts Working

  • The time required for Eplerender-25 mg Tablet 10's to start to work: The time required for Eplerender-25 mg Tablet 10's to start to work is 1 to 2 hours after administration.
  • The time for which the effects of Eplerender-25 mg Tablet 10's last: The effect of Eplerender-25 mg Tablet 10's lasts for 1 to 2 days.

What if you forget to take Eplerender-25 mg Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you frequently forget your doses.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid Eplerender-25 mg Tablet 10's if you have certain medical conditions: Do not take this medicine if you have high potassium levels in your blood, severe kidney impairment, or significantly reduced kidney function.
  • Be careful with other medicines that affect potassium: Avoid using potassium-sparing diuretics or potassium supplements unless specifically prescribed and monitored by your doctor.
  • Inform your doctor about all medications you take: Certain medicines, including ketoconazole, itraconazole, and clarithromycin, can interact with Eplerender-25 mg Tablet 10's and may increase the risk of side effects.
  • Do not use if you have a history of allergy: Avoid this medicine if you have ever experienced an allergic reaction to Eplerender-25 mg Tablet 10's or any of its ingredients.
  • Attend all monitoring appointments: Keep all scheduled blood test appointments so your doctor can regularly check your kidney function and potassium levels.
  • Consult your doctor before taking pain relievers: Avoid using over-the-counter pain medicines, such as ibuprofen or naproxen, without medical advice, as they may affect how this medicine works and increase the risk of kidney problems.
  • Change positions slowly: Rise gradually from a sitting or lying position to help reduce dizziness and prevent falls.
  • Do not stop treatment abruptly: Continue taking this medicine as prescribed, even if you feel well, as stopping it suddenly may cause your blood pressure or heart condition to worsen.
  • Monitor potassium levels: Your doctor may check your blood potassium levels before starting Eplerender-25 mg Tablet 10's and at regular intervals during treatment to help prevent complications from high potassium levels.
  • Check kidney function regularly: Kidney function tests may be performed periodically to ensure your kidneys are working properly and can safely handle the medication.
  • Attend scheduled follow-up tests: Potassium levels and kidney function are often assessed within the first week of treatment, again after about one month, and periodically thereafter as advised by your doctor.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Potassium supplements or potassium-sparing water pills: Taking these together with Eplerender-25 mg Tablet 10's can lead to dangerously high potassium levels in your blood.
  • ACE inhibitors or ARBs (blood pressure medicines): Combining these can increase the risk of elevated blood potassium and kidney strain.
  • NSAID pain relievers (like ibuprofen): May reduce the blood-pressure-lowering effect of Eplerender-25 mg Tablet 10's and increase the risk of severe kidney damage.
  • Strong CYP3A4 inhibitors (such as ketoconazole or clarithromycin): Can significantly increase the concentration of Eplerender-25 mg Tablet 10's in your body, raising the risk of severe side effects.

Drug-Food Interactions

  • Grapefruit and grapefruit juice: Can interfere with how your body processes this medicine, leading to increased levels in your blood and a higher risk of side effects.
  • Potassium-rich salt substitutes: Must be avoided to prevent dangerous potassium accumulation.

Drug-Disease Interactions

  • High blood potassium (hyperkalemia): Do not take this medicine if you already have high potassium levels.
    Severe kidney disease: Can worsen kidney function and lead to dangerous potassium buildup.
  • Diabetes with kidney complications: Increases the likelihood of developing dangerously high potassium levels in the blood.

Drug-Drug Interactions

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How does the drug interact with Eplerender-25 mg Tablet:
Co-administration of Eplerender-25 mg Tablet and Clarithromycin may significantly increase the blood levels and effects of Eplerender-25 mg Tablet.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Clarithromycin with Eplerender-25 mg Tablet is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
How does the drug interact with Eplerender-25 mg Tablet:
Co-administration of Eplerender-25 mg Tablet and Ritonavir may significantly increase the blood levels of Eplerender-25 mg Tablet.

How to manage the interaction:
Taking Ritonavir and Eplerender-25 mg Tablet together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Eplerender-25 mg Tablet:
Combining Eplerender-25 mg Tablet with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between spironolactone and Eplerender-25 mg Tablet, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneNefazodone
Critical
How does the drug interact with Eplerender-25 mg Tablet:
Coadministration of Nefazodone with Eplerender-25 mg Tablet can increase the levels of Eplerender-25 mg Tablet in the body.

How to manage the interaction:
Taking Nefazodone with Eplerender-25 mg Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Eplerender-25 mg Tablet:
The blood levels and effects of Eplerender-25 mg Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Although there is a possible interaction between Eplerender-25 mg Tablet and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
EplerenonePotassium iodide
Critical
How does the drug interact with Eplerender-25 mg Tablet:
Combining Eplerender-25 mg Tablet with Potassium iodide may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium iodide and Eplerender-25 mg Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenonePotassium citrate
Critical
How does the drug interact with Eplerender-25 mg Tablet:
Taking Eplerender-25 mg Tablet with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Eplerender-25 mg Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Eplerender-25 mg Tablet:
Coadministration of Ketoconazole with Eplerender-25 mg Tablet can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking ketoconazole with Eplerender-25 mg Tablet is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
How does the drug interact with Eplerender-25 mg Tablet:
Using Eplerender-25 mg Tablet together with Potassium chloride may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking potassium chloride with Eplerender-25 mg Tablet is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Eplerender-25 mg Tablet:
Coadministration of posaconazole with Eplerender-25 mg Tablet can increase the blood levels of Eplerender-25 mg Tablet. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between posaconazole and Eplerender-25 mg Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ALDOSTERONE ANTAGONISTS]

FAQs

Eplerender-25 mg Tablet 10's is used to treat heart failure and hypertension (high blood pressure).
Eplerender-25 mg Tablet 10's contains Eplerenone, which works by blocking the action of aldosterone, a natural substance that raises blood pressure. It also slows the progression of heart failure by reducing heart damage.
Yes, Eplerender-25 mg Tablet 10's can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or if you are taking potassium supplements along with Eplerender-25 mg Tablet 10's. Please monitor your electrolyte level regularly to avoid increased blood potassium levels. Consult your doctor if you experience muscle cramps, diarrhoea, nausea, dizziness or headache.
No, Eplerender-25 mg Tablet 10's is not a blood thinner. It is a selective aldosterone blocker used to treat heart failure and high blood pressure.
Eplerender-25 mg Tablet 10's contains Eplerenone. It is an aldosterone antagonist type of potassium-sparing diuretic.
For high blood pressure, it may take up to 4 weeks to see the full benefit. For heart failure, the medicine works internally to protect your heart even if you do not feel an immediate difference. Talk to your doctor if you have concerns about your progress.
No, Eplerender-25 mg Tablet 10's is not known to cause erectile dysfunction. It does not have any effect on fertility.
Do not discontinue Eplerender-25 mg Tablet 10's without consulting the doctor. To treat your condition effectively, keep taking Eplerender-25 mg Tablet 10's for the prescribed duration.
Potassium-sparing diuretics increase urine production without depleting potassium reserves. Eplerender-25 mg Tablet 10's permits the body to lose sodium while retaining potassium. The amount of potassium may rise as a result. Therefore, your doctor may regularly check your potassium levels.
Your doctor might have recommended Eplerenone instead of Losartan as a blood pressure medication because losartan may have been insufficient in lowering your blood pressure. However, Eplerenone increases the risk of elevated potassium levels, which may not be suitable for you. Hence, the doctor has prescribed Eplerender-25 mg Tablet 10's along with hydrochlorothiazide to prevent the rise in potassium levels.
Before starting Eplerender-25 mg Tablet 10's, let the doctor know if you are taking aspirin. Taking aspirin with Eplerender-25 mg Tablet 10's may decrease the effects of Eplerender-25 mg Tablet 10's. Contact your doctor if you experience signs of high blood pressure such as headache, blurred vision, trouble concentrating, or dizziness.
Eplerender-25 mg Tablet 10's may cause side effects like nausea, vomiting, dizziness, diarrhoea, and elevated potassium levels. Most of these side effects of Eplerender-25 mg Tablet 10's do not require medical attention and resolve over time. However, if the side effects are persistent, reach out to your doctor.
Yes, you can take Eplerender-25 mg Tablet 10's with or without food. Taking it at the same time and in the same manner each day helps keep the medicine working consistently. Talk to your doctor if you have questions about your daily routine.
Your doctor will order blood tests to check your kidney function and measure the amount of potassium in your blood. Because Eplerender-25 mg Tablet 10's helps your body retain potassium, these tests ensure your levels remain in a safe range. Talk to your doctor for more details.
No, you should avoid salt substitutes because most of them contain potassium instead of sodium. Combining them with Eplerender-25 mg Tablet 10's can lead to dangerously high potassium levels in your blood. Talk to your doctor or pharmacist about safe dietary alternatives.
Unlike some other water pills, Eplerender-25 mg Tablet 10's does not typically cause a significant increase in urination for most patients. However, it still effectively helps your body remove excess salt and fluid. Talk to your doctor if you notice any unusual changes.
Dizziness can occur, especially when you first start taking this medicine or if your dose is increased. Rise slowly from sitting or lying down to help prevent this. If the dizziness is severe or does not go away, talk to your doctor.
You should avoid taking NSAID pain relievers like ibuprofen or naproxen without consulting your doctor first. These medicines can reduce the effectiveness of Eplerender-25 mg Tablet 10's and increase the risk of kidney problems. Talk to your doctor or pharmacist about safer pain relief options.
It is best to limit or avoid alcohol while taking Eplerender-25 mg Tablet 10's. Alcohol can increase the risk of side effects like dizziness, lightheadedness, or fainting by further lowering your blood pressure. Talk to your doctor about what is safe for you.
Eplerender-25 mg Tablet 10's can increase potassium levels in the blood and may affect kidney function in some people. Regular blood tests help your doctor ensure the medicine remains safe and effective and allow early detection of any problems.

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Country of origin

India

Manufacturer/Marketer address

Elder House Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai 400053.
Other Info - EPL0023
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