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Epsolin ER 300 Tablet is an anticonvulsant medicine used in the treatment of epilepsy/fits and cardiac arrhythmias. This medicine works by preventing the brain's abnormal electrical activity during seizures. Common side effects include dizziness, drowsiness, excitation, headache, tiredness, loss of appetite, nausea, vomiting, constipation, and trouble sleeping.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Epsolin ER 300 Tablet

Epsolin ER 300 Tablet is a prescription medication used to control and prevent various types of seizures. It is primarily prescribed for people with epilepsy to help stabilise brain activity and reduce the frequency of sudden episodes. Your doctor may also prescribe it to prevent seizures during or after brain surgery.

To get the best results, you must take Epsolin ER 300 Tablet consistently every single day. Taking it at the same time each day keeps a steady level of the medicine in your body. You can take this medicine with or without food, but you must be consistent—always take it the same way. Keeping a regular sleep schedule and avoiding exhaustion can also help improve your results.

While taking Epsolin ER 300 Tablet , you may experience mild side effects like drowsiness, dizziness, or slightly swollen gums. However, you must contact your doctor immediately if you experience severe symptoms like a painful skin rash, fever, swollen lymph nodes, or new mood changes.

Talk to your doctor before starting this medicine if you have a history of liver damage, kidney issues, or diabetes. Do not take this if you have had a severe allergic reaction to similar seizure medications in the past, or if you have certain genetic markers that increase your risk of severe skin reactions.

Epsolin ER 300 Tablet can interact with many other medicines, including common pain relievers, blood thinners, and hormonal birth control, which can make those medicines less effective or raise your risk of side effects. Avoid alcohol while taking this medicine because it can dangerously alter the medication levels in your blood. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, consult your doctor to discuss your specific risks.

Uses of Epsolin ER 300 Tablet

Epsolin ER 300 Tablet helps prevent and control seizures by stabilising abnormal electrical activity in the brain. Your doctor may recommend it for the following conditions:

  • Epilepsy and control of seizures: Epsolin ER 300 Tablet helps prevent and control generalized tonic-clonic (grand mal) seizures and complex partial (psychomotor) seizures by regulating electrical activity in the brain.
  • Prevention of seizures during neurosurgery: Epsolin ER 300 Tablet is used to prevent seizures that may occur during or immediately after brain surgery or head trauma.

Key Benefits

Epsolin ER 300 Tablet helps prevent seizures, protect the brain, and improve your quality of life. Key benefits include:

  • Controls seizures: Helps reduce the risk of sudden, unexpected seizures by stabilising the brain's electrical activity, allowing you to carry out daily activities with greater confidence.
  • Supports daily living: Helps you participate more safely in school, work, and social activities by lowering the likelihood of seizure episodes.
  • Protects the recovering brain: Provides protection against seizures during recovery from head injuries or brain surgery, supporting a safer healing process.
Side effects of Epsolin ER 300 Tablet
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Eat a balanced diet rich in anti-inflammatory foods, such as leafy greens, berries, and fatty fish.
  • Avoid consuming excessive processed foods, sugary drinks, and snacks.
  • Drink plenty of water to stay hydrated.
  • Practice stress-reducing techniques, such as yoga or meditation, to help manage stress and promote overall well-being.
  • If you're concerned about skin nodules, consult a dermatologist for personalized advice and treatment options.
  • Wear an eye patch or opaque contact lens or lens applied to glasses to block the vision of one eye to minimize double vision.
  • Use prisms (lenses applied to glasses) to correct double vision due to small misalignments.
  • Try doing some eye exercises such as moving the target towards nose slowly or focussing on a detailed target like thin stick or small text in a magazine.
  • If you feel eye pain, develop bulging eyes, have weakness, headache or double vision, consult a doctor immediately.
  • Eat eggs for zinc and other nutrients that support healthy vision.
  • Consume blueberries as antioxidants to combat eye strain.
  • Include broccoli in your diet for diverse eye-boosting nutrients.
  • Eat sweet potatoes as a natural source of vitamin A.
  • Snack on almonds for vitamin E and eye protection.
  • Add tomatoes to your diet for lycopene and vision protection.
  • Perform exercises that improve binocular vision, such as dot-to-dot cards, coloring within lines, and Brock string tests.
  • Wear an eye patch and perform tasks like playing games and solving puzzles.
  • Patching and eye exercises can improve symptoms.

Directions for Use

  • Epsolin ER 300 Tablet can be taken with or without food, although taking it with food may help avoid stomach upset.
  • Take it as your doctor prescribes, usually at the same time each day.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.

How Epsolin ER 300 Tablet Works

Epsolin ER 300 Tablet contains phenytoin sodium, which belongs to a class of medicines called anticonvulsants. The brain relies on tiny electrical impulses sent through nerve cells to function. During a seizure, these electrical signals become hyperactive, firing too rapidly and causing a temporary disruption in brain function. Epsolin ER 300 Tablet works by targeting the sodium channels in your brain cells. By limiting the movement of sodium ions across these cell membranes, the medication prevents the rapid, repetitive firing of electrical impulses. This stabilises the nerve cells, preventing the abnormal electrical activity from starting or spreading to other parts of the brain.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Epsolin ER 300 Tablet to prevent unpleasant side effects.

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Pregnancy

Caution

Do not take Epsolin ER 300 Tablet if you are pregnant unless prescribed by the doctor. Your doctor will prescribe Epsolin ER 300 Tablet only if the benefits outweigh the risks. If you become pregnant while taking Epsolin ER 300 Tablet , then do not stop taking Epsolin ER 300 Tablet without consulting your doctor.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns about this; your doctor will decide whether Epsolin ER 300 Tablet can be given to breastfeeding mothers.

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Driving

Caution

Epsolin ER 300 Tablet may cause dizziness and drowsiness, drive and operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Epsolin ER 300 Tablet should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Epsolin ER 300 Tablet should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Epsolin ER 300 Tablet can be given to children only when prescribed by the doctor.

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Heart

Caution

Epsolin ER 300 Tablet should be taken with caution in patients with heart problems, as it may cause irregular heartbeat or low blood pressure. Therefore, please inform your doctor before using Epsolin ER 300 Tablet .

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Geriatrics

Caution

Epsolin ER 300 Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.

What if I have taken an overdose of Epsolin ER 300 Tablet

If you suspect an overdose, seek immediate emergency medical attention. Symptoms of an overdose can include severe dizziness, slurred speech, rapid and uncontrollable eye movements, loss of physical balance, tremors, or slow breathing.

Diet & Lifestyle Advise

  • Maintain excellent dental hygiene: Brush your teeth at least twice a day and floss daily. Regular dental cleanings are highly recommended, as this medication can cause your gums to swell and bleed.
  • Support your bone health: Long-term use of this medicine can weaken your bones. Talk to your doctor about whether you should take daily calcium and Vitamin D supplements.
  • Avoid alcohol completely: Drinking alcohol can unpredictably change the amount of medicine in your body, either making it less effective or dangerously increasing its side effects.
  • Establish a regular sleep schedule: Sleep deprivation is a known trigger for seizures. Aim for consistent, restful sleep every night to support your treatment.
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How Soon It Starts Working

The time required for Epsolin ER 300 Tablet to start to work: The peak effect of Epsolin ER 300 Tablet can be seen within 3 hours for an immediate-release tablet and 4 to 12 hours for an extended-release tablet. The time for which the effects of Epsolin ER 300 Tablet last: Epsolin ER 300 Tablet effect can last about 2 to 3 days.

What if you forget to take Epsolin ER 300 Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 4 hours away, skip the missed dose and return to your regular schedule. Do not take two doses at the same time to make up for a missed one. If you miss doses for more than two days in a row, talk to your doctor or pharmacist.

Storage

•Store at 20°C to 25°C in the original, tightly closed container to protect it from light and moisture.•Keep out of the sight and reach of children and pets.

Drug Warnings

  • Do not stop suddenly: Never stop taking Epsolin ER 300 Tablet without your doctor's advice, as this may trigger continuous, life-threatening seizures.
  • Attend blood tests: Keep all scheduled appointments so your doctor can monitor your medicine levels and ensure safe treatment.
  • Watch for skin rash: Check your skin daily and contact your healthcare provider immediately if you develop any rash, even if it seems mild.
  • Avoid driving or operating machinery: Do not drive, ride a bicycle, or operate machinery until you know how this medicine affects your alertness and balance.
  • Inform healthcare professionals: Tell your doctor, dentist, and other healthcare providers that you are taking Epsolin ER 300 Tablet before receiving any treatment or undergoing medical procedures.

Drug-Drug Interactions

verifiedApollotooltip
  • Hormonal birth control: Epsolin ER 300 Tablet can make oral contraceptive pills, patches, and implants less effective, increasing the risk of unplanned pregnancy.
  • Blood thinners (like warfarin): May change how your body processes blood thinners, requiring closer monitoring of your blood clotting times.
  • Other seizure medicines: Taking this with other anticonvulsants can alter the levels of both medications in your system.
  • Stomach acid reducers: Certain medications for heartburn or ulcers can interfere with how your body absorbs Epsolin ER 300 Tablet .
PhenytoinCimetidine
Critical

Drug-Drug Interactions

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PhenytoinCimetidine
Critical
How does the drug interact with Epsolin ER 300 Tablet:
Using Epsolin ER 300 Tablet together with cimetidine may increase the effects of Epsolin ER 300 Tablet.

How to manage the interaction:
Taking Epsolin ER 300 Tablet with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
How does the drug interact with Epsolin ER 300 Tablet:
Co-administration of Epsolin ER 300 Tablet and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Epsolin ER 300 Tablet is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Epsolin ER 300 Tablet:
Using rilpivirine together with Epsolin ER 300 Tablet may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Epsolin ER 300 Tablet is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Epsolin ER 300 Tablet:
Taking ceritinib with Epsolin ER 300 Tablet may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Epsolin ER 300 Tablet with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Epsolin ER 300 Tablet:
Using venetoclax together with Epsolin ER 300 Tablet may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Epsolin ER 300 Tablet with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Epsolin ER 300 Tablet:
Using praziquantel together with Epsolin ER 300 Tablet may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Epsolin ER 300 Tablet with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Epsolin ER 300 Tablet:
Using ranolazine together with Epsolin ER 300 Tablet may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Epsolin ER 300 Tablet with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Epsolin ER 300 Tablet:
Using lurasidone together with Epsolin ER 300 Tablet may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Epsolin ER 300 Tablet is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epsolin ER 300 Tablet:
Coadministration of Epsolin ER 300 Tablet and Everolimus may decrease the blood levels of everolimus, which may make Everolimus less effective.

How to manage the interaction:
Although taking Epsolin ER 300 Tablet and Everolimus together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
PhenytoinMethadone
Severe
How does the drug interact with Epsolin ER 300 Tablet:
Coadministration of Epsolin ER 300 Tablet and Methadone may reduce the blood levels of Methadone, which could make it less effective.

How to manage the interaction:
Although taking Epsolin ER 300 Tablet and methadone together can result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Can dangerously increase central nervous system side effects such as severe drowsiness and loss of coordination.
    Tube feedings (enteral nutrition): Can significantly lower the absorption of Epsolin ER 300 Tablet . Talk to your doctor about how to separate your medication doses from your feeding schedule.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Epsolin ER 300 Tablet belongs to the group of medicines called anticonvulsants used to treat epilepsy/seizures, and prevent seizures during/after brain surgery or after traumatic brain injury. It is also be used to treat trigeminal neuralgia (facial nerve pain).
Epsolin ER 300 Tablet works by controlling the brain's overactivity that causes seizures (fits). Thus, Epsolin ER 300 Tablet helps control epileptic fits involving muscle spasms and jerking.
Epsolin ER 300 Tablet can make hormonal birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and a diaphragm with spermicide to prevent pregnancy.
Please do not stop taking Epsolin ER 300 Tablet without consulting your doctor, as it may cause increased seizures. Continue taking Epsolin ER 300 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Epsolin ER 300 Tablet .
Epsolin ER 300 Tablet may cause swelling in the gums. Brush and floss your teeth daily; visit your dentist if you experience this problem regularly.
Epsolin ER 300 Tablet may affect the breakdown of the blood sugar/glucose and may prevent insulin release, thereby leading to high blood sugar. So, contact a doctor before using Epsolin ER 300 Tablet if you have diabetes.
A typical seizure can last from a few seconds to a few minutes. If it lasts more than 5 minutes, consult the doctor immediately.
Epsolin ER 300 Tablet should be taken as advised by the doctor at the same time daily. Swallow Epsolin ER 300 Tablet as a whole with a glass of water. Do not chew, break or crush it.
Avoid consuming alcohol while taking Epsolin ER 300 Tablet as it may cause unpleasant side effects. Consult the doctor if you have any concerns.
Epsolin ER 300 Tablet stays in the system for a few days. However, this might vary from person to person.
The symptoms that occur if you take more than the recommended dose are loss of balance, nausea, vomiting, tremors, twitching eye movements, slurred speech, muscle stiffness or weakness, light-headedness, fainting, and slow or shallow breathing. Consult the doctor if you notice any of these symptoms.
Yes, the overdose of Epsolin ER 300 Tablet may be fatal. Therefore, take Epsolin ER 300 Tablet in the dose prescribed by the doctor.
People who are allergic to any of the components in Epsolin ER 300 Tablet or hydantoins should avoid taking this medicine.
Epsolin ER 300 Tablet may have interactions with ibuprofen. Dose adjustment may be needed to take both medicines together. Consult the doctor before taking Epsolin ER 300 Tablet with ibuprofen.
Epsolin ER 300 Tablet may cause jerky eye movements, loss of energy, thinking or behavioural problems, slow or clumsy movements, and mood changes in children. Talk to the doctor if you notice any of these signs in your child during treatment with Epsolin ER 300 Tablet .
Epsolin ER 300 Tablet is not known to cause weight gain. However, if you notice any weight changes, manage it by exercising regularly, cutting down on high-calorie diets, eating a nutrition-rich diet, reducing processed and sugary foods, and staying hydrated.
Yes, Epsolin ER 300 Tablet may cause sleepiness as a common side effect. If you experience sleepiness, avoid driving and operating machinery.
Yes, Epsolin ER 300 Tablet may affect birth control by reducing the effectiveness of hormonal contraceptives like birth control pills, rings, patches, and injections. Consult the doctor regarding other methods of contraception to be used while on treatment with Epsolin ER 300 Tablet .
The side effects of Epsolin ER 300 Tablet include drowsiness, dizziness, weakness, restlessness, and constipation. Consult the doctor if any of these symptoms persist or worsen.
Blood tests are necessary to measure the exact amount of medicine in your body. This helps your doctor ensure the dose is high enough to prevent seizures but low enough to avoid toxic side effects. Talk to your doctor about your test schedule.
Taking this medicine during pregnancy can pose risks to the developing baby. However, controlling seizures is also highly important. If you are pregnant or planning to become pregnant, talk to your doctor immediately to weigh the risks and benefits.
You must contact your doctor immediately if you develop any skin rash. Some rashes associated with this medicine can become severe and require urgent medical care. Talk to your doctor right away if you notice skin changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - EPS0010
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