Apollo
logo
  1. Home
  2. salt
  3. Phenytoin Sodium

Phenytoin Sodium

About Phenytoin Sodium

Phenytoin Sodium is a prescription medication used to control and prevent various types of seizures. It is primarily prescribed for people with epilepsy to help stabilise brain activity and reduce the frequency of sudden episodes. Your doctor may also prescribe it to prevent seizures during or after brain surgery.

To get the best results, you must take Phenytoin Sodium consistently every single day. Taking it at the same time each day keeps a steady level of the medicine in your body. You can take this medicine with or without food, but you must be consistent—always take it the same way. Keeping a regular sleep schedule and avoiding exhaustion can also help improve your results.

While taking Phenytoin Sodium, you may experience mild side effects like drowsiness, dizziness, or slightly swollen gums. However, you must contact your doctor immediately if you experience severe symptoms like a painful skin rash, fever, swollen lymph nodes, or new mood changes.

Talk to your doctor before starting this medicine if you have a history of liver damage, kidney issues, or diabetes. Do not take this if you have had a severe allergic reaction to similar seizure medications in the past, or if you have certain genetic markers that increase your risk of severe skin reactions.

Phenytoin Sodium can interact with many other medicines, including common pain relievers, blood thinners, and hormonal birth control, which can make those medicines less effective or raise your risk of side effects. Avoid alcohol while taking this medicine because it can dangerously alter the medication levels in your blood. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, consult your doctor to discuss your specific risks.

Uses of Phenytoin Sodium

Phenytoin Sodium is used in the treatment of epilepsy and seizures. The detailed uses of Phenytoin Sodium are as follows:
• Treatment of Epilepsy/Seizures: It helps manage epilepsy and seizures by stabilising electrical activity in the brain.
• Prevention of Seizures During/After Brain Surgery or Traumatic Brain Injury: It prevents seizures during or after brain surgery or following a traumatic brain injury.
• Treatment of Trigeminal Neuralgia: It may also treat trigeminal neuralgia, a condition that causes severe facial nerve pain.

Medicinal Benefits

Phenytoin Sodium helps prevent seizures, protect the brain, and improve your quality of life. Key benefits include:

  • Controls seizures: Helps reduce the risk of sudden, unexpected seizures by stabilising the brain's electrical activity, allowing you to carry out daily activities with greater confidence.
  • Supports daily living: Helps you participate more safely in school, work, and social activities by lowering the likelihood of seizure episodes.
  • Protects the recovering brain: Provides protection against seizures during recovery from head injuries or brain surgery, supporting a safer healing process.

Directions for Use

  • Phenytoin Sodium can be taken with or without food, although taking it with food may help avoid stomach upset.
  • Take it as your doctor prescribes, usually at the same time each day.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Phenytoin Sodium

Common Side Effects (Usually mild):

  • Drowsiness, dizziness, or feeling unsteady
  • Nausea, vomiting, or constipation
  • Headaches or difficulty sleeping
  • Swollen, tender, or bleeding gums


Serious Side Effects (Call a doctor right away):

  • A new skin rash, red or purple spots, peeling skin, or blistering
  • Fever, sore throat, swollen glands, or joint pain
  • Yellowing of your eyes or skin, dark urine, or severe upper stomach pain (signs of liver damage)
  • Unusual bruising, pale skin, or feeling extremely tired
  • New or worsening anxiety, depression, mood swings, or thoughts of hurting yourself

Drug Warnings

  • Do not stop suddenly: Never stop taking Phenytoin Sodium without your doctor's advice, as this may trigger continuous, life-threatening seizures.
  • Attend blood tests: Keep all scheduled appointments so your doctor can monitor your medicine levels and ensure safe treatment.
  • Watch for skin rash: Check your skin daily and contact your healthcare provider immediately if you develop any rash, even if it seems mild.
  • Avoid driving or operating machinery: Do not drive, ride a bicycle, or operate machinery until you know how this medicine affects your alertness and balance.
  • Inform healthcare professionals: Tell your doctor, dentist, and other healthcare providers that you are taking Phenytoin Sodium before receiving any treatment or undergoing medical procedures.

Drug Interactions

  • Hormonal birth control: Phenytoin Sodium can make oral contraceptive pills, patches, and implants less effective, increasing the risk of unplanned pregnancy.
  • Blood thinners (like warfarin): May change how your body processes blood thinners, requiring closer monitoring of your blood clotting times.
  • Other seizure medicines: Taking this with other anticonvulsants can alter the levels of both medications in your system.
  • Stomach acid reducers: Certain medications for heartburn or ulcers can interfere with how your body absorbs Phenytoin Sodium.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • ACETAMINOPHEN
  • WARFARIN
  • CLOPIDOGREL
  • GABAPENTIN
  • PREGABALIN
  • DIAZEPAM
  • FLUOXETINE
  • QUETIAPINE
  • FUROSEMIDE
  • ATORVASTATIN
  • SILDENAFIL
  • LEVOTHYROXINE
  • DELAVIRDINE
  • ERGOCALCIFEROL
  • CHOLECALCIFEROL
  • FOLIC ACID
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking Phenytoin Sodium to prevent unpleasant side effects.

    • Safety Warning

      Pregnancy

      caution

      Do not take Phenytoin Sodium if you are pregnant unless prescribed by the doctor. Your doctor will prescribe Phenytoin Sodium only if the benefits outweigh the risks. If you become pregnant while taking Phenytoin Sodium, then do not stop taking Phenytoin Sodium without consulting your doctor.

    • Safety Warning

      Breast Feeding

      caution

      Please consult your doctor if you have any concerns about this; your doctor will decide whether Phenytoin Sodium can be given to breastfeeding mothers.

    • Safety Warning

      Driving

      caution

      Phenytoin Sodium may cause dizziness and drowsiness, drive and operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Phenytoin Sodium should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Phenytoin Sodium should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      Phenytoin Sodium can be given to children only when prescribed by the doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain excellent dental hygiene: Brush your teeth at least twice a day and floss daily. Regular dental cleanings are highly recommended, as this medication can cause your gums to swell and bleed.
    • Support your bone health: Long-term use of this medicine can weaken your bones. Talk to your doctor about whether you should take daily calcium and Vitamin D supplements.
    • Avoid alcohol completely: Drinking alcohol can unpredictably change the amount of medicine in your body, either making it less effective or dangerously increasing its side effects.
    • Establish a regular sleep schedule: Sleep deprivation is a known trigger for seizures. Aim for consistent, restful sleep every night to support your treatment.

    Patients Concern

    Disease/Condition Glossary

    Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterised by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

    FAQs

    Phenytoin Sodium belongs to the group of medicines called anticonvulsants used to treat epilepsy/seizures, and prevent seizures during/after brain surgery or after traumatic brain injury. It is also be used to treat trigeminal neuralgia (facial nerve pain).

    Phenytoin Sodium works by controlling the brain's overactivity that causes seizures (fits). Thus, Phenytoin Sodium helps control epileptic fits involving muscle spasms and jerking.

    Phenytoin Sodium can make hormonal birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and a diaphragm with spermicide to prevent pregnancy.

    Please do not stop taking Phenytoin Sodium without consulting your doctor, as it may cause increased seizures. Continue taking Phenytoin Sodium for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Phenytoin Sodium.

    Phenytoin Sodium may cause swelling in the gums. Brush and floss your teeth daily; visit your dentist if you experience this problem regularly.

    Phenytoin Sodium may affect the breakdown of the blood sugar/glucose and may prevent insulin release, thereby leading to high blood sugar. So, contact a doctor before using Phenytoin Sodium if you have diabetes.

    A typical seizure can last from a few seconds to a few minutes. If it lasts more than 5 minutes, consult the doctor immediately.

    Phenytoin Sodium should be taken as advised by the doctor at the same time daily. Swallow Phenytoin Sodium as a whole with a glass of water. Do not chew, break or crush it.

    Avoid consuming alcohol while taking Phenytoin Sodium as it may cause unpleasant side effects. Consult the doctor if you have any concerns.

    Phenytoin Sodium stays in the system for a few days. However, this might vary from person to person.

    The symptoms that occur if you take more than the recommended dose are loss of balance, nausea, vomiting, tremors, twitching eye movements, slurred speech, muscle stiffness or weakness, light-headedness, fainting, and slow or shallow breathing. Consult the doctor if you notice any of these symptoms.

    Yes, the overdose of Phenytoin Sodium may be fatal. Therefore, take Phenytoin Sodium in the dose prescribed by the doctor.

    People who are allergic to any of the components in Phenytoin Sodium or hydantoins should avoid taking this medicine.

    Phenytoin Sodium may have interactions with ibuprofen. Dose adjustment may be needed to take both medicines together. Consult the doctor before taking Phenytoin Sodium with ibuprofen.

    Phenytoin Sodium may cause jerky eye movements, loss of energy, thinking or behavioural problems, slow or clumsy movements, and mood changes in children. Talk to the doctor if you notice any of these signs in your child during treatment with Phenytoin Sodium.

    Phenytoin Sodium is not known to cause weight gain. However, if you notice any weight changes, manage it by exercising regularly, cutting down on high-calorie diets, eating a nutrition-rich diet, reducing processed and sugary foods, and staying hydrated.

    Yes, Phenytoin Sodium may cause sleepiness as a common side effect. If you experience sleepiness, avoid driving and operating machinery.

    Yes, Phenytoin Sodium may affect birth control by reducing the effectiveness of hormonal contraceptives like birth control pills, rings, patches, and injections. Consult the doctor regarding other methods of contraception to be used while on treatment with Phenytoin Sodium.

    The side effects of Phenytoin Sodium include drowsiness, dizziness, weakness, restlessness, and constipation. Consult the doctor if any of these symptoms persist or worsen.

    Blood tests are necessary to measure the exact amount of medicine in your body. This helps your doctor ensure the dose is high enough to prevent seizures but low enough to avoid toxic side effects. Talk to your doctor about your test schedule.

    Taking this medicine during pregnancy can pose risks to the developing baby. However, controlling seizures is also highly important. If you are pregnant or planning to become pregnant, talk to your doctor immediately to weigh the risks and benefits.

    You must contact your doctor immediately if you develop any skin rash. Some rashes associated with this medicine can become severe and require urgent medical care. Talk to your doctor right away if you notice skin changes.

    Author Details

    Doctor image
    We provide you with authentic, trustworthy and relevant information.
    Apollo 247 Floating Button