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Esamlovin-1.25 Tablet is used to treat high blood pressure and angina (chest pain). It contains S-amlodipine, which works by relaxing the blood vessels; this reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. In some cases, this medicine may cause side effects such as fatigue, headache, nausea, dizziness, and abdominal pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

S AMLODIPINE-1.25MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Esamlovin-1.25 Tablet

Esamlovin-1.25 Tablet is an oral prescription medication primarily used to manage high blood pressure and prevent chest pain caused by reduced blood flow to the heart. It serves to protect your cardiovascular system by keeping your blood vessels relaxed and open. This helps to significantly reduce the risk of suffering a heart attack or stroke in the future.

For optimal results, this medication must be taken consistently once every day at the same time. You can take it either with or without food, as your daily meals do not interfere with how the medicine is absorbed. Adopting a low-sodium diet and engaging in regular exercise can further enhance the positive effects of this treatment on your blood pressure.

While using this medicine, some patients might experience mild side effects such as swelling in the ankles or hands, headaches, and tiredness. Although these are common, you should seek immediate medical assistance if you experience severe chest pain, a rapidly pounding heartbeat, or sudden fainting.

Before starting your treatment, you must consult your doctor if you have a history of liver damage or narrowing of the heart valves. Do not take this if you have extremely low blood pressure or if you are allergic to any active or inactive components of this medication.

This medication can interact with other blood pressure drugs, certain antifungal medicines, and alcohol, potentially causing your blood pressure to drop to unsafe levels. Pregnant women, breastfeeding mothers, and elderly individuals should consult their doctor to ensure this treatment is safe for them.

Uses of Esamlovin-1.25 Tablet

Esamlovin-1.25 Tablet is used to manage high blood pressure and prevent chest pain caused by reduced blood flow to the heart. The detailed uses of Esamlovin-1.25 Tablet are as follows:

  • High blood pressure (Hypertension): Esamlovin-1.25 Tablet relaxes and widens the blood vessels, allowing blood to flow more easily and helping to lower elevated blood pressure levels to a safer, healthier range.
  • Chronic stable angina (Chest pain): It helps prevent episodes of chest pain by improving blood flow and oxygen delivery to the heart muscle, especially during physical exertion.
  • Vasospastic angina (Prinzmetal's angina): It prevents spasms in the coronary arteries, ensuring a steady supply of blood to the heart to avoid sudden, painful chest spasms.

Key Benefits

Esamlovin-1.25 Tablet helps manage high blood pressure and chest pain by improving blood flow and reducing the workload on the heart. With regular use, it supports long-term cardiovascular health and helps lower the risk of serious complications.

  • Helps Control High Blood Pressure: By maintaining blood pressure within a healthy range throughout the day, Esamlovin-1.25 Tablet helps reduce strain on the heart and protects vital organs such as the kidneys, brain, and heart from long-term damage.
  • Helps Prevent Chest Pain (Angina): By improving blood supply to the heart, Esamlovin-1.25 Tablet helps reduce the frequency and severity of angina attacks, allowing you to carry out daily activities and light physical exercise more comfortably.
  • Supports Long-Term Heart Health: Consistent blood pressure control with Esamlovin-1.25 Tablet helps reduce the risk of complications such as stroke, heart failure, kidney disease, and other cardiovascular events, supporting overall wellbeing.
Side effects of Esamlovin-1.25 Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Take Esamlovin-1.25 Tablet with or without food as advised by your doctor.
  • It is advised to take Esamlovin-1.25 Tablet once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush or chew it.

How Esamlovin-1.25 Tablet Works

Esamlovin-1.25 Tablet contains S amlodipine, which belongs to a class of medications known as calcium channel blockers. It works by blocking calcium from entering the muscle cells of your blood vessels and heart. When calcium enters these cells, it causes them to contract and tighten. By stopping this process, the medication allows the blood vessels to relax and widen. This widening reduces the resistance your heart faces when pumping blood, which lowers your overall blood pressure. It also dilates the arteries supplying the heart, ensuring that more oxygen-rich blood reaches the heart muscle to prevent chest pain.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Esamlovin-1.25 Tablet to avoid unpleasant side effects like lowering of blood pressure (hypotension).

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Pregnancy

Consult your doctor

Esamlovin-1.25 Tablet is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking Esamlovin-1.25 Tablet .

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Breast Feeding

Consult your doctor

Esamlovin-1.25 Tablet is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

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Driving

Unsafe

Drive with caution, as Esamlovin-1.25 Tablet can cause drowsiness and impair driving ability.

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Liver

Caution

Esamlovin-1.25 Tablet should be used with caution, especially if you have or have had a history of liver disease.

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Kidney

Safe if prescribed

Esamlovin-1.25 Tablet is generally safe to prescribe in patients with kidney diseases, and dose adjustment is generally not required. However, your doctor will decide the appropriate dosage strength depending on the severity of your condition.

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Children

Consult your doctor

Esamlovin-1.25 Tablet can be given safely to children aged 6-12 years, provided the dose has been prescribed by a child specialist. Esamlovin-1.25 Tablet should not be given to the children without consulting a child specialist.

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Heart

Safe if prescribed

Esamlovin-1.25 Tablet is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Exercise caution before using Esamlovin-1.25 Tablet in older patients. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Esamlovin-1.25 Tablet

If you take more than your prescribed dose, seek emergency medical attention immediately. An overdose can cause your blood pressure to drop dangerously low, leading to severe dizziness, confusion, and a rapid heart rate.

Diet & Lifestyle Advise

  • Limit your sodium intake: Reduce the amount of salt in your meals and avoid processed foods, as excess sodium raises blood pressure.
  • Eat a heart-healthy diet: Incorporate more fresh fruits, vegetables, whole grains, and low-fat dairy into your daily meals.
  • Stay physically active: Engage in moderate exercises, such as brisk walking or swimming, for at least 30 minutes a day after consulting your doctor.
  • Manage your stress levels: Practice relaxation techniques such as deep breathing, meditation, or yoga to help maintain stable blood pressure.
  • Avoid smoking and limit alcohol: Smoking damages your blood vessels, and excessive alcohol can raise your blood pressure and interfere with your medication.
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Have a query?

How Soon It Starts Working

  • The time required for Esamlovin-1.25 Tablet to start to work: The time required for Esamlovin-1.25 Tablet to show its action is unknown.
  • The time for which the effects of Esamlovin-1.25 Tablet last: Esamlovin-1.25 Tablet effect lasts for 24 hours.

What if you forget to take Esamlovin-1.25 Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Esamlovin-1.25 Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F and 86°F). •Keep the medicine in its original blister pack or container to protect it from direct light, heat, and moisture.

Drug Warnings

  • Check your blood pressure regularly at home and keep a log to share with your doctor during visits.
  • Stand up slowly from a sitting or lying position to reduce the risk of dizziness, lightheadedness, or falls.
  • Avoid drinking grapefruit juice or eating grapefruit while on this medication, as it can increase the drug's levels in your blood and lead to severe side effects.
  • Do not stop taking this medicine suddenly, as this can cause your blood pressure to spike or your chest pain to return.
  • Let your dentist or surgeon know you are taking this medication before undergoing any medical procedures.
  • Avoid driving or operating machinery if you feel dizzy or sleepy after taking your dose.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Taking this medicine with other blood pressure-lowering agents can cause your blood pressure to drop excessively.
  • Certain antifungal medications (such as ketoconazole) and antibiotics (such as erythromycin) may increase the levels of Esamlovin-1.25 Tablet in your body, increasing the risk of side effects.
  • Some heart medications, such as beta-blockers or digoxin, may require careful monitoring when taken alongside this medicine.
AmlodipineDantrolene
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Esamlovin-1.25 Tablet:
Using Esamlovin-1.25 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Esamlovin-1.25 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Esamlovin-1.25 Tablet:
Using Esamlovin-1.25 Tablet and phenytoin together may drastically lower Esamlovin-1.25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Esamlovin-1.25 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esamlovin-1.25 Tablet:
Using phenobarbital and Esamlovin-1.25 Tablet may drastically lower Esamlovin-1.25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Esamlovin-1.25 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Esamlovin-1.25 Tablet:
Using Esamlovin-1.25 Tablet and mitotane together may drastically lower Esamlovin-1.25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Esamlovin-1.25 Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Esamlovin-1.25 Tablet:
Using a combination of Esamlovin-1.25 Tablet and enzalutamide may drastically lower Esamlovin-1.25 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Esamlovin-1.25 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Esamlovin-1.25 Tablet:
Coadministration of Esamlovin-1.25 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Esamlovin-1.25 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Esamlovin-1.25 Tablet:
Coadministration of Esamlovin-1.25 Tablet and rifampicin together may lower Esamlovin-1.25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Esamlovin-1.25 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esamlovin-1.25 Tablet:
Coadministration of lemborexant and Esamlovin-1.25 Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Esamlovin-1.25 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esamlovin-1.25 Tablet:
Using Esamlovin-1.25 Tablet and rifabutin together may lower Esamlovin-1.25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Esamlovin-1.25 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Esamlovin-1.25 Tablet:
When Esamlovin-1.25 Tablet is taken with Fosphenytoin, it may decrease the blood levels of Esamlovin-1.25 Tablet, which may make Esamlovin-1.25 Tablet less effective.

How to manage the interaction:
Although taking Esamlovin-1.25 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice can significantly increase the concentration of this medicine in your bloodstream, raising the risk of severe side effects like low blood pressure and swelling.
     
S AMLODIPINE-1.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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S AMLODIPINE-1.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
The consumption of grapefruit juice with Esamlovin-1.25 Tablet may slightly increase plasma concentrations of Esamlovin-1.25 Tablet. Avoid consuming grapefruit juice while being treated with Esamlovin-1.25 Tablet. however, if you experience headache, hypotension, syncope, tachycardia, or edema consult a doctor.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Esamlovin-1.25 Tablet is used to treat hypertension (high blood pressure) and angina (chest pain).
Esamlovin-1.25 Tablet contains S-amlodipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.
The common side effects of Esamlovin-1.25 Tablet are fatigue, ankle swelling, sleepiness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, nausea, dizziness, palpitations, and abdominal pain resolves after some time.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and will not recommend discontinuing it.
In case you have missed a dose of Esamlovin-1.25 Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it is time for you to take your next dose, then do not take both doses together. Take only one dose, taking a double dose of Esamlovin-1.25 Tablet will lead to low blood pressure.
Yes, Esamlovin-1.25 Tablet is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
Eating well, exercising regularly, maintaining a healthy weight, quitting smoking, getting enough sleep, and managing stress are all lifestyle changes that can help lower blood pressure.
Uncontrolled hypertension gradually destroys the arteries, causing them to harden. As the arteries constrict and become less flexible, the heart works harder to circulate blood. Uncontrolled high blood pressure can cause a stroke, heart attack, heart failure, and other heart problems, damage to the kidneys, memory, and eyesight, and contribute to erectile dysfunction.
Esamlovin-1.25 Tablet may cause itching, although it is not common in everyone. It usually fades with time; however, contact your doctor if you experience severe itching.
Esamlovin-1.25 Tablet is generally safe to prescribe in patients with mild kidney dysfunctions, and dose adjustment is generally not required. However, your doctor will decide the appropriate dosage strength depending on the severity of your condition.
You can take it at any time of day but try to make sure it's around the same time every day.
No, Esamlovin-1.25 Tablet is not a beta-blocker. It belongs to a class of medicines known as calcium channel blockers.
More frequent or more severe chest pain, rapid, pounding, or irregular heartbeat and fainting. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.
Esamlovin-1.25 Tablet does not interfere with contraception. However, some hormonal methods of contraception, such as the combination pill and contraceptive patch, are generally not indicated if you have high blood pressure.
Consuming significant amounts of grapefruit or grapefruit juice can raise the levels of amlodipine in your blood and exacerbate adverse effects. If you are affected, you may need to avoid eating or drinking grapefruit while taking amlodipine. Also, avoid alcohol consumption, quit smoking, and limit salt intake (Aim for no more than 6g of salt a day).
Drinking alcohol can make amlodipine lower your blood pressure more than you need. This can make you sleepy or dizzy or bring on a headache.
Esamlovin-1.25 Tablet can make some people feel dizzy. If this happens to you, do not drive a car, ride a bike, or use tools or machinery until you feel better.
Esamlovin-1.25 Tablet contains S-amlodipine, a calcium channel blocker.
Esamlovin-1.25 Tablet is generally safe to take for a long time. In fact, it works best when you take it for a long time.
Esamlovin-1.25 Tablet can be given safely to children aged 6-12 years, provided a child specialist has prescribed the dose. Esamlovin-1.25 Tablet should only be given to the children by consulting a child specialist.
Esamlovin-1.25 Tablet is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking Esamlovin-1.25 Tablet .
Avoid exceeding the recommended dose, as it could lead to an overdose. Symptoms of overdose may include excessive peripheral vasodilation with marked low blood pressure and reflex tachycardia. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
Yes, some patients experience dizziness or drowsiness, especially when first starting the medicine or after a dose increase. Avoid driving or operating machinery until you know how this medication affects you, and talk to your doctor if these symptoms persist.
Yes, you can take Esamlovin-1.25 Tablet with or without food. The most important thing is to take it consistently at the same time every day to keep your blood pressure stable. Talk to your doctor if you have persistent stomach issues.
Some pain relievers, particularly nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, can reduce the effectiveness of blood pressure medications and strain your kidneys. Talk to your doctor or pharmacist before combining these medications.

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Country of origin

India

Manufacturer/Marketer address

6, Nandalal Bose Sarani,Kolkata -700071.
Other Info - ESA0028
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