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compositionComposition:ESOMEPRAZOLE-40MG
prescription
Prescription Medicine
info
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Esomecad 40 Injection 5 ml belongs to the class of proton pump inhibitors. It is used as a short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It contains esomeprazole, which helps decrease the amount of acid in the stomach. Some of the common side effects include headache, diarrhoea, constipation, abdominal pain, flatulence, vomiting, and nausea.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Esomecad 40 Injection 5 ml

Esomecad 40 Injection 5 ml is a prescription medicine injected into a vein to treat conditions caused by excess stomach acid, such as severe acid reflux and stomach ulcers. It is typically used when you are temporarily unable to take medicines by mouth. This treatment helps heal acid damage in your oesophagus and stomach, providing crucial relief when you need it most.

This medicine is usually given once daily as directed by your healthcare provider, and consistent use is key to helping your stomach lining heal completely. Since it is injected directly, it does not rely on food intake to work, though making positive lifestyle changes can greatly support your recovery. Avoiding trigger foods like citrus and caffeine, eating smaller meals, and not lying down right after eating can significantly improve your overall results.

While receiving this medicine, you might experience mild, common side effects such as headaches, gas, or mild redness at the injection site. However, if you develop severe watery diarrhoea, muscle spasms, or signs of a serious allergic reaction, you must consult your doctor immediately. Your healthcare team is trained to monitor you closely for any unusual reactions during your treatment.

Before starting this medicine, talk to your doctor if you have severe liver damage, low magnesium levels in your blood, or weak bones, as your treatment may require close monitoring. Do not take this medicine if you have had a severe allergic reaction to similar acid-reducing drugs in the past.

Esomecad 40 Injection 5 ml can interact with certain blood thinners and HIV medications, reducing their effectiveness or changing how your body processes them. It is also important to avoid smoking and limit alcohol, as both can irritate your stomach lining and delay healing. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor to ensure this treatment is safe for your specific situation.
 

Uses of Esomecad 40 Injection 5 ml

Esomecad 40 Injection 5 ml is prescribed to reduce excessive stomach acid and is used to treat conditions involving acid-related damage, ulcer healing, prevention of rebleeding, and rare disorders of excessive acid production.

  • Gastroesophageal Reflux Disease (GERD) with esophagitis: Esomecad 40 Injection 5 ml helps heal the severe inflammation and erosions in your food pipe caused by stomach acid washing backward.
  • Stomach and Duodenal Ulcers: Esomecad 40 Injection 5 ml helps heal painful sores in the lining of your stomach or the upper part of your small intestine.
  • Prevention of Rebleeding after Endoscopy: Esomecad 40 Injection 5 ml is injected to significantly lower the risk of ulcers bleeding again after they have been treated during an endoscopy procedure.
  • Zollinger-Ellison Syndrome: Esomecad 40 Injection 5 ml helps manage this rare condition where the stomach produces extreme, harmful amounts of acid.
     

Key Benefits

The benefits of Esomecad 40 Injection 5 ml include relieving acid-related symptoms, promoting healing of damaged tissues, preventing serious complications, and improving comfort during recovery.

  • Relieves severe acid-related symptoms: Reduces heartburn, acid reflux, and pain caused by excessive stomach acid.
  • Promotes healing of ulcers and oesophagitis: Creates an environment that allows ulcers and inflamed tissues to heal more effectively.
  • Reduces the risk of ulcer rebleeding: Helps prevent recurrent bleeding after successful endoscopic treatment of bleeding ulcers.
  • Improves comfort while eating and swallowing: Reduces irritation in the digestive tract, making swallowing and eating more comfortable during recovery.
     
Side effects of Esomecad 40 Injection 5 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Esomecad 40 Injection 5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Esomecad 40 Injection 5 ml Works

Esomecad 40 Injection 5 ml contains Esomecad 40 Injection 5 ml, a proton pump inhibitor (PPI) that helps reduce the amount of acid produced in the stomach. Esomecad 40 Injection 5 ml works by blocking the proton pumps present in the acid-producing cells of the stomach lining. These pumps are responsible for releasing stomach acid that helps digest food. By inhibiting their action, Esomecad 40 Injection 5 ml significantly reduces the production of stomach acid. Lowering stomach acid creates a less acidic environment, allowing the lining of the oesophagus, stomach, and upper intestine to heal. It also helps relieve symptoms such as heartburn, acid reflux, and stomach discomfort while preventing further acid-related damage. Together, these actions help reduce stomach acid, promote healing of acid-related damage, and provide long-lasting relief from conditions such as acid reflux, gastric ulcers, and gastro-oesophageal reflux disease (GORD).
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Alcohol

Caution

Drinking alcohol or alcoholic beverages with Esomecad 40 Injection 5 ml may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid/limit alcohol.

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Pregnancy

Caution

Consult a doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Esomecad 40 Injection 5 ml.

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Breast Feeding

Caution

Consult a doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Esomecad 40 Injection 5 ml.

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Driving

Caution

In rare cases, Esomecad 40 Injection 5 ml may cause dizziness and impaired vision. Do not drive if you experience these symptoms.

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Liver

Caution

Esomecad 40 Injection 5 ml should be taken with precaution in patients with liver disease. Inform your doctor before receiving Esomecad 40 Injection 5 ml if you have had a liver impairment/disorder history. The doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Esomecad 40 Injection 5 ml should be taken with precaution in patients with kidney disease. Inform your doctor before receiving Esomecad 40 Injection 5 ml if you have had a history of severe kidney impairment/disorder. The doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Esomecad 40 Injection 5 ml can be given to children aged 1 month or older under the supervision of a healthcare provider.

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Heart

Caution

Esomecad 40 Injection 5 ml should be administered with caution in patients with heart problems. Therefore, please inform your doctor before receiving Esomecad 40 Injection 5 ml.

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Geriatrics

Caution

Esomecad 40 Injection 5 ml should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Esomecad 40 Injection 5 ml

Because this medicine is given by healthcare professionals, an overdose is highly unlikely. However, if you suspect you have received too much of this medicine, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Avoid trigger foods: Stay away from highly acidic foods, citrus fruits, tomatoes, chocolate, onions, spicy meals, and fatty dishes that can worsen acid reflux.
  • Limit certain beverages: Reduce your intake of caffeine, carbonated drinks, and alcohol, as these can relax the muscle valve between your oesophagus and stomach, causing acid to leak upward.
  • Eat smaller, frequent meals: Consuming smaller portions helps prevent your stomach from becoming overly full, reducing the pressure that drives acid upward.
  • Stay upright after eating: Avoid lying down or bending over for at least two to three hours after eating to allow gravity to keep acid in your stomach.
  • Manage stress: High stress levels can increase stomach acid production and worsen ulcer symptoms; consider practising relaxation techniques like deep breathing or meditation.
     
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How Soon It Starts Working

The time required for Esomecad 40 Injection 5 ml to start to work: Esomecad 40 Injection 5 ml ideally starts to show its action immediately after the administration.

The time for which the effects of Esomecad 40 Injection 5 ml last: Esomecad 40 Injection 5 ml effect lasts for 9 hours.

What if you forget to take Esomecad 40 Injection 5 ml

Since this medicine is usually injected by a healthcare provider in a clinical setting, missing a dose is unlikely. However, if you miss a scheduled appointment for your injection, contact your healthcare provider right away to reschedule and get guidance on your treatment plan.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inspect the solution: Always inspect the liquid before it is injected; it should be clear and colourless to pale yellow. Do not use it if you notice any cloudiness, discolouration, or floating particles.
  • Rotate injection sites: If you are receiving multiple injections over several days, ask your provider to rotate the injection site to minimise vein irritation and discomfort.
  • Check for kidney health: Use of acid-reducing medicines can sometimes cause kidney problems, so alert your doctor if you experience changes in your urination, such as blood in the urine or a sudden decrease in volume.
  • Monitor bone health: Daily use of this medicine over a long period (more than a year) may increase the risk of bone fractures; discuss with your doctor if you need calcium or vitamin D supplements.
  • Report severe skin reactions: Seek immediate medical care if you develop a severe, peeling skin rash or blisters, as this can be a rare but life-threatening reaction.
     

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Esomecad 40 Injection 5 ml and may require dose adjustments, additional monitoring, or alternative treatment:

  • Blood thinners (like clopidogrel): Esomecad 40 Injection 5 ml may reduce the effectiveness of certain blood thinners, increasing your risk of blood clots.
  • Certain HIV medications (like atazanavir or nelfinavir): This medicine reduces stomach acid, which can prevent your body from properly absorbing these antiviral medications, making them less effective.
  • Antifungal medications (like ketoconazole or itraconazole): Lower stomach acid levels can significantly decrease the absorption and effectiveness of these medicines.
  • Methotrexate: Taking Esomecad 40 Injection 5 ml may increase the levels of methotrexate in your blood, raising the risk of severe side effects.

 

EsomeprazoleRilpivirine
Critical
EsomeprazoleAtazanavir
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esomecad 40 Injection 5 ml:
Esomecad 40 Injection 5 ml may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esomecad 40 Injection 5 ml with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleAtazanavir
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Esomecad 40 Injection 5 ml reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between Esomecad 40 Injection 5 ml and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Coadministration of erlotinib and Esomecad 40 Injection 5 ml can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Esomecad 40 Injection 5 ml together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Esomecad 40 Injection 5 ml can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esomecad 40 Injection 5 ml with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazolePazopanib
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Esomecad 40 Injection 5 ml decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Esomecad 40 Injection 5 ml and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Esomecad 40 Injection 5 ml may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking Esomecad 40 Injection 5 ml with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Using Dasatinib together with Esomecad 40 Injection 5 ml may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Esomecad 40 Injection 5 ml together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleGefitinib
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Taking gefitinib with Esomecad 40 Injection 5 ml may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Esomecad 40 Injection 5 ml and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Esomecad 40 Injection 5 ml. Do not stop taking any medications without consulting a doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Co-administration of methotrexate and Esomecad 40 Injection 5 ml can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Esomecad 40 Injection 5 ml with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Esomecad 40 Injection 5 ml:
Taking nelfinavir with Esomecad 40 Injection 5 ml may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Esomecad 40 Injection 5 ml and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Esomecad 40 Injection 5 ml when used as directed.
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTACIDS]

FAQs

Esomecad 40 Injection 5 ml belongs to the class of drugs known as proton pump inhibitors, used for the short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It also reduces the risk of further ulcer bleeding following an endoscopy in adults.
Esomecad 40 Injection 5 ml impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach, thereby helping treat GERD.
No. Gas and acidity are two different conditions. Acidity is caused by improper functioning of the valve (sphincter) located at the junction of the stomach and the food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.
On long-term treatment, Esomecad 40 Injection 5 ml may cause low magnesium levels. Low magnesium levels can make you tired, confused, and dizzy and cause muscle cramps, shakiness, and an irregular heartbeat. Inform the doctor if you experience any of these symptoms.
Esomecad 40 Injection 5 ml may alter certain medical tests, like secretin stimulation tests and urine screening tests for tetrahydrocannabinol (THC). So, if you are undergoing diagnostic tests, inform your doctor that you are taking Esomecad 40 Injection 5 ml.
Esomecad 40 Injection 5 ml may slightly increase the risk of hip, wrist, or spine fracture, especially if you take it for longer than a year. Let your doctor know if you have osteoporosis or are taking corticosteroids (which can increase the risk of osteoporosis).
Typically, Esomecad 40 Injection 5 ml is injected or infused by a healthcare professional in a clinic or hospital. In rare cases where home administration is prescribed, you or a caregiver will receive detailed training from a nurse. Talk to your doctor if you have questions about where you will receive your doses.
Your doctor may prescribe the injection form of Esomecad 40 Injection 5 ml if you are temporarily unable to swallow medicines by mouth, or if you have a severe condition like a bleeding ulcer that requires immediate, direct acid suppression. Talk to your doctor about transitioning to oral tablets once you can swallow comfortably.
You should avoid alcohol while being treated with Esomecad 40 Injection 5 ml. Alcohol can directly irritate your stomach lining, worsen acid reflux, and delay the healing of your ulcers or oesophagus. Talk to your doctor or pharmacist for personalised advice.
Long-term use of acid-reducing medicines (usually for more than three years) can make it harder for your body to absorb vitamin B12 from food. If you need this medicine for a long period, your doctor may monitor your vitamin levels. Talk to your doctor if you have concerns.
If you develop watery, severe diarrhoea that does not go away, do not take anti-diarrhoea medicines without consulting your provider. This could be a sign of a serious bacterial infection in your gut. Talk to your doctor immediately.
There is limited research on the use of the injected form of this medicine in pregnant women. Your doctor will weigh the benefits against any potential risks before prescribing it. Talk to your doctor if you are pregnant or planning to become pregnant.
In rare cases, medicines like Esomecad 40 Injection 5 ml can cause swelling or inflammation in the kidneys. Alert your doctor if you notice a sudden decrease in how much you urinate, blood in your urine, or unusual swelling. Talk to your doctor if you have pre-existing kidney issues.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad 380015, Gujarat, India.
Other Info - ESO0484

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