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Esoplay-40 Tablet 10's



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Product Details

About Esoplay-40 Tablet 10's

Esoplay-40 Tablet 10's belongs to the class of drugs known as Proton pump inhibitor which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour).

Esoplay-40 Tablet 10's helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. Esoplay-40 Tablet 10's prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Take Esoplay-40 Tablet 10's 1-2hours prior food. You are advised to take Esoplay-40 Tablet 10's for as long as your doctor has prescribed it for you depending on your medical condition. An adult taking Esoplay-40 Tablet 10's might have common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). In the case of children taking Esoplay-40 Tablet 10's might report upper respiratory tract infections (URI), headache, fever, diarrhoea, vomiting, rash, and abdominal pain.  These side effects are temporary and may get resolve after some time however if this side persists contact the doctor.

Esoplay-40 Tablet 10's is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, allergic to Esoplay-40 Tablet 10's, or will have an endoscopy in the future. Prolonged intake of Esoplay-40 Tablet 10's may cause deficiency of Vitamin B12 and low level of calcium, magnesium, and Vitamin D leading to osteoporosis.

Uses of Esoplay-40 Tablet 10's

Hyperacidity, Heartburn, Stomach ulcer, Zollinger-Ellison syndrome

Medicinal Benefits

Esoplay-40 Tablet 10's is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome. Esoplay-40 Tablet 10's works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mothers, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Esoplay-40 Tablet 10's in doses as prescribed by your doctor with the help of a measuring cup.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.


Store in a cool and dry place away from sunlight

Side Effects of Esoplay-40 Tablet 10's

In adults

  • Headache
  • Diarrhoea
  • Nausea
  • Abdominal pain
  • Vomiting
  • Flatulence
  • Dizziness
  • Arthralgia (joint pain)


In Children

  • Upper respiratory tract infections (URI)
  • Headache
  • Fever
  • Diarrhoea
  • Vomiting
  • Rash
  • Abdominal pain

In-Depth Precautions and Warning

Drug Warnings

You should avoid taking Esoplay-40 Tablet 10's if you are allergic to Esoplay-40 Tablet 10's or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Esoplay-40 Tablet 10's may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Esoplay-40 Tablet 10's may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Esoplay-40 Tablet 10's may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. 

Drug Interactions

Drug-Drug Interactions: Esoplay-40 Tablet 10's may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir, rilpivirine),  anti-viral drugs (nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Food Interactions: Esoplay-40 Tablet 10's interact with St John's wort plant that is used as an anti-depressant. This plant may affect the working of Esoplay-40 Tablet 10's. So avoid its intake with Esoplay-40 Tablet 10's.

Drug-Disease Interactions: Esoplay-40 Tablet 10's should be not given in patients with Clostridium difficile associated diarrhea, magnesium and Vitamin B-12 deficiency (increased risk of bone fracture), atrophic gastritis (inflammed lining of stomach), and acute interstitial nephritis (inflammed cells of kidney).

Drug-Drug Interactions Checker List:

  • Safety Advice

    • Safety Warning



      Drinking alcohol with Esoplay-40 Tablet 10's may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Esoplay-40 Tablet 10's.

    • Safety Warning



      Esoplay-40 Tablet 10's isn't usually recommended during pregnancy as there's no firm evidence it's safe. So, contact a doctor before intake of Esoplay-40 Tablet 10's. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

    • Safety Warning

      Breast Feeding


      Esoplay-40 Tablet 10's passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Esoplay-40 Tablet 10's. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

    • Safety Warning



      In some cases, Esoplay-40 Tablet 10's may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

    • Safety Warning



      Esoplay-40 Tablet 10's should be taken with precaution in patients with liver disease.

    • Safety Warning



      Patients with kidney disease should consult a doctor before taking Esoplay-40 Tablet 10's.

    • Safety Warning



      Esoplay-40 Tablet 10's should not be prescribed for children under 5 years of age. Esoplay-40 Tablet 10's is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

    Habit Forming


    Diet & Lifestyle Advise

    • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
    • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
    • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
    • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
    • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

    Special Advise

    Prolonged intake of Esoplay-40 Tablet 10's may be associated with increased risk of Clostridium difficile associated diarrhea, magnesium and Vitamin B-12 deficiency (increased risk of bone fracture), atrophic gastritis (inflammed lining of stomach), and acute interstitial nephritis (inflammed cells of kidney).


    Other Information (ESO0295)

    This item is Not Returnable.

    Expires on or after - Jun-2023

    Patients Concern

    Disease/Condition Glossary

    Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine) (the duodenum). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumor of the pancreas causes excessive acid production leading to peptic ulcers.


    Esoplay-40 Tablet 10's is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.

    Prolonged intake of Esoplay-40 Tablet 10's may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

    No. Esoplay-40 Tablet 10's prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

    Yes. Esoplay-40 Tablet 10's can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

    It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.

    There's no firm evidence to suggest that taking Esoplay-40 Tablet 10's will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.

    You can eat and drink normally while taking Esoplay-40 Tablet 10's. However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

    No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.


    Esoplay-40 Tablet 10's


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    10 Tablet in 1 Strip