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  3. Esorol-LS Capsule 10's

Esorol-LS Capsule 10's, Pack of 10 CAPSULES
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Esorol-LS Capsule is used to treat gastro-oesophageal reflux disease (GERD). It contains Esomeprazole and Levosulpiride, which reduces acid production and works by increasing the stomach and intestinal movement and prevents the backflow of food and acid into the mouth. Thus, it helps in preventing acid reflux, thereby providing relief from acidity and heartburn. In some cases, you may experience certain common side effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ESOMEPRAZOLE-40MG + LEVOSULPIRIDE-75MG

Manufacturer/Marketer :

Cista Medicorp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Esorol-LS Capsule

Esorol-LS Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.

Esorol-LS Capsule contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esorol-LS Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

You are advised to take Esorol-LS Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Esorol-LS Capsule if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Esorol-LS Capsule may increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. Esorol-LS Capsule may cause drowsiness and dizziness, so drive only if you are alert. Esorol-LS Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Esorol-LS Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Esorol-LS Capsule

Esorol-LS Capsule is used in treating Gastro-oesophageal reflux disease(a chronic condition when stomach contents leak back into the oesophagus).

Directions for Use

• Esorol-LS Capsule should be taken 1 hour before a meal, preferably in the morning.• It is usually taken once daily or as prescribed by your doctor.• Swallow Esorol-LS Capsule as a whole with a glass of water.• Do not crush, break, or open it.

Medicinal Benefits

Esorol-LS Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Esorol-LS Capsule is a combination of two drugs, namely: Esomeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esorol-LS Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

How Esorol-LS Capsule Works

Esorol-LS Capsule contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esorol-LS Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Storage

Keep Esorol-LS Capsule out of reach and sight of children.
Side effects of Esorol-LS Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Esorol-LS Capsule

Do not take more than the prescribed dose of Esorol-LS Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Esorol-LS Capsule if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking Esorol-LS Capsule if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Esorol-LS Capsule may increase the risk of bone fractures. Do not take Esorol-LS Capsule if you are pregnant or breastfeeding. Esorol-LS Capsule may cause dizziness and drowsiness, so drive only if you are alert. Esorol-LS Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Esorol-LS Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. 

Drug-Drug Interactions

verifiedApollotooltip
EsomeprazoleRilpivirine
Critical
EsomeprazoleNelfinavir
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esorol-LS Capsule:
Esorol-LS Capsule may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esorol-LS Capsule with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Esorol-LS Capsule:
Taking nelfinavir with Esorol-LS Capsule may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Esorol-LS Capsule and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazolePazopanib
Severe
How does the drug interact with Esorol-LS Capsule:
Esorol-LS Capsule decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Esorol-LS Capsule and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with Esorol-LS Capsule:
Using Dasatinib together with Esorol-LS Capsule may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Esorol-LS Capsule together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Esorol-LS Capsule:
Co-administration of methotrexate and Esorol-LS Capsule can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Esorol-LS Capsule with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
EsomeprazoleTacrolimus
Severe
How does the drug interact with Esorol-LS Capsule:
Taking tacrolimus with Esorol-LS Capsule may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Esorol-LS Capsule with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with Esorol-LS Capsule:
Esorol-LS Capsule may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking Esorol-LS Capsule with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with Esorol-LS Capsule:
Combining Esorol-LS Capsule with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Esorol-LS Capsule with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleClopidogrel
Severe
How does the drug interact with Esorol-LS Capsule:
Coadministration of Clopidogrel with Esorol-LS Capsule may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Esorol-LS Capsule together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Esorol-LS Capsule:
Esorol-LS Capsule can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esorol-LS Capsule with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

  • Maintain a healthy weight by regular exercising.

  • Avoid lying down after eating as it causes acid reflux.

  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.

  • Practise relaxation techniques and avoid stress by doing yoga or meditation.

  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 

  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Esorol-LS Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Esorol-LS Capsule . Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

bannner image

Pregnancy

Unsafe

Esorol-LS Capsule should not be taken if you are pregnant. Consult your doctor before taking Esorol-LS Capsule if you are pregnant.

bannner image

Breast Feeding

Unsafe

Esorol-LS Capsule may pass into breast milk. Consult your doctor before taking Esorol-LS Capsule if you are breastfeeding.

bannner image

Driving

Caution

Esorol-LS Capsule may cause dizziness, drowsiness and blurred vision. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Unsafe

Esorol-LS Capsule should not be used in patients with hepatic impairment. Consult your doctor before taking Esorol-LS Capsule if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Esorol-LS Capsule if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Esorol-LS Capsule should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

Esorol-LS Capsule is used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.

Esorol-LS Capsule is a combination of two drugs, namely: Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esorol-LS Capsule helps in preventing acid reflux, thereby providing relief from acidity.

Diarrhoea might be a side-effect of Esorol-LS Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Esorol-LS Capsule with nelfinavir (a drug used to treat HIV infections). Consult your doctor before taking Esorol-LS Capsule with other medicines to rule out unpleasant side-effects.

Esorol-LS Capsule contains esomeprazole which might increase the risk of fracture in the wrist, hip or spine. This mainly occurs in people taking Esorol-LS Capsule for longer durations. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, your doctor may prescribe calcium and vitamin D supplements.

Esorol-LS Capsule may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Esorol-LS Capsule .

Dry mouth could be a side-effect of Esorol-LS Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Esorol-LS Capsule works by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid production in the stomach to prevent discomfort.

Esorol-LS Capsule contains Esomeprazole and Levosulpiride.

The usual recommendation is to take it one hour before the meal, preferably in the morning.

Yes, Esorol-LS Capsule may cause dizziness and drowsiness, so drive or operate machinery only if you are alert.

Yes, it can help to ease stomach pain.

Store Esorol-LS Capsule according to the instructions on the leaflet, away from sunlight, at a temperature not exceeding 25°C. Dispose of unused medicine. Keep it out of reach from pets and children.

You'll usually take Esorol-LS Capsule in the morning one hour before the food or as directed by the physician.

Esorol-LS Capsule is contraindicated to use if you are allergic to any of its contents if you are taking nelfinavir (anti-HIV) if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. It is also contraindicated to use in pregnant and breastfeeding women.

Esorol-LS Capsule might increase the risk of wrist, hip or spine fracture. This mainly occurs in people taking Esorol-LS Capsule for longer durations.

Common side effects of Esorol-LS Capsule may include headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Esorol-LS Capsule should not be given to children as safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

175, First Floor Industrial Area, Phase-1 Panchkula(HR), 134113
Other Info - ESO0273

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:38 AM IST

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Reference

  1. https://www.ciplamed.com/content/esomac-l-capsules
  2. https://www.drugs.com/mtm/esomeprazole.html

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