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compositionComposition:ATENOLOL-50MG+S AMLODIPINE-2.5MG
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Prescription Medicine
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Espin AT Tablet is used to treat hypertension (high blood pressure). It helps relax blood vessels and supports smooth blood flow. This lowers blood pressure and reduces cardiac strain. It reduces the risk of cardiovascular complications and supports heart health.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ATENOLOL-50MG+S AMLODIPINE-2.5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Espin AT Tablet

Espin AT Tablet is a combination medicine prescribed to treat high blood pressure (hypertension). By lowering high blood pressure, this medicine helps prevent future heart attacks, strokes, and kidney problems. It is designed to keep your cardiovascular system running smoothly and safely.

For the best results, you should take Espin AT Tablet once daily at the same time each day. You can take this medicine with or without food, but consistency is key to keeping your blood pressure stable. Along with taking this medication, adopting a heart-healthy diet low in salt and staying active will greatly improve your treatment outcomes.

While taking Espin AT Tablet , some people may experience mild side effects like drowsiness, headaches, or cold hands and feet. However, if you notice serious issues such as an unusually slow heart rate, severe dizziness, or swelling in your ankles, you should contact your doctor immediately. Do not ignore these signs, as they require professional medical evaluation.

Before starting Espin AT Tablet , tell your doctor if you have a history of asthma, lung disease, or severe blood circulation issues. Do not take this if you have certain heart conditions, such as a very slow heart rate or serious heart block. Always share your complete medical history with your healthcare provider to ensure this medication is safe for you.

This medicine can interact with alcohol, which may cause a sudden drop in your blood pressure and increase dizziness. Smoking damages blood vessels and increases your risk of heart disease, stroke, and high blood pressure. Quitting smoking can improve your overall cardiovascular health and support the benefits of your blood pressure treatment. If you are pregnant, planning to breastfeed, or are an elderly individual, talk to your doctor or pharmacist before using this medicine to weigh the benefits and risks.

Uses of Espin AT Tablet

The following are the common conditions for which Espin AT Tablet is prescribed: 

  • High blood pressure (Hypertension): Espin AT Tablet helps by relaxing and widening your blood vessels, making it easier for blood to flow and lowering the overall pressure in your cardiovascular system.
  • Angina (chronic chest pain): By reducing the workload on your heart and improving blood flow, Espin AT Tablet helps prevent chest pain caused by reduced blood flow to the heart muscle.

Key Benefits

The following benefits highlight how Espin AT Tablet helps control blood pressure, protect your heart, and improve your daily quality of life:

  • Provides effective blood pressure control: It helps maintain healthy blood pressure levels, reducing strain on the heart and blood vessels.
  • Reduces the risk of cardiovascular complications: Long-term blood pressure control helps lower the risk of serious complications such as heart attack, stroke, and kidney damage.
  • Prevents angina symptoms: By improving blood flow to the heart and decreasing its workload, it helps reduce the frequency and severity of chest pain, allowing you to remain more physically active.
  • Offers convenient combination therapy: Combining two medicines with complementary actions into a single tablet simplifies treatment and may improve adherence to your prescribed medication regimen.
Side effects of Espin AT Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Reducing the amount of time you spend outside and indoors in the cold.
  • keeping your hands warm by donning mittens, gloves, or other protective clothing.
  • Observing a skincare regimen that safeguards your fingers and hands.
  • To improve circulation, give your hands and feet a little massage.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Espin AT Tablet can be taken with or without food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Espin AT Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Espin AT Tablet Works

Espin AT Tablet contains two active medicines that work together to lower blood pressure and reduce the workload on your heart. S-Amlodipine is a calcium channel blocker that primarily relaxes the smooth muscle in blood vessel walls by reducing calcium entry into these cells. This widens the blood vessels, improves blood flow, and lowers blood pressure. It also has a smaller effect on the heart, helping reduce its workload. Atenolol is a cardioselective (beta-1 selective) beta-blocker. It reduces the effects of adrenaline mainly on the heart, slowing the heart rate and reducing the force of contraction. This lowers blood pressure and decreases the heart's workload.  Together, these medicines help control high blood pressure, improve blood flow, reduce strain on the heart, and lower the risk of complications such as heart attack and stroke.
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Alcohol

Unsafe

Alcohol may lower your blood pressure. It would help if you avoid or limit consuming alcohol whilst taking this medicine.

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Pregnancy

Caution

Espin AT Tablet is not recommended during pregnancy since it may have harmful effects on the unborn baby. However, it is advised to seek medical advice before using Espin AT Tablet if you plan to conceive or already pregnant.

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Breast Feeding

Caution

Espin AT Tablet is not recommended during breastfeeding since it may pass into the breast milk. Please consult your doctor before using Espin AT Tablet if you are a lactating mother.

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Driving

Unsafe

Espin AT Tablet may cause side effects due to a reduction in blood pressure, such as dizziness or fatigue. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Espin AT Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Espin AT Tablet .

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Children

Unsafe

Espin AT Tablet is not recommended for use by people under 18.

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Heart

Caution

Espin AT Tablet should be used with caution in patients with cardiovascular disease. Therefore, please inform your doctor before using Espin AT Tablet .

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Geriatrics

Caution

Espin AT Tablet should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of Espin AT Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Espin AT Tablet

If you suspect an overdose, seek immediate medical attention or contact a poison control centre right away. Symptoms of an overdose may include extreme dizziness, fainting, an exceptionally slow heartbeat, or severe weakness.

Diet & Lifestyle Advise

  • Reduce salt intake: Limit your daily sodium intake by avoiding processed foods and not adding extra salt to your meals, which directly helps lower blood pressure.
  • Eat a heart-healthy diet: Focus on meals rich in whole grains, fruits, vegetables, lean proteins, and low-fat dairy products.
  • Engage in regular exercise: Aim for at least 30 minutes of moderate physical activity, like brisk walking, most days of the week. Talk to your doctor before starting any new exercise routine.
  • Limit alcohol and quit smoking: Avoid smoking completely as nicotine damages blood vessels, and limit alcohol consumption to prevent sudden blood pressure changes.

Health Queries

Which medicine is safe to take for high blood pressure?

Vikas Singh

Vikas Singh

M Pharmacy

The safest blood pressure medication depends on your age, blood pressure level, kidney function, diabetes status, heart health, and other medical conditions. Different people may need different medicines, so treatment should be selected by a doctor after checking your blood pressure and overall health, rather than starting tablets on your own. Commonly prescribed blood pressure medicines help relax blood vessels, reduce pressure on the heart, or remove extra salt and fluid from the body. Taking the wrong medicine or dose without supervision may cause dizziness, fainting, swelling, or very low blood pressure. Along with medicines, reducing salt intake, regular exercise, maintaining a healthy weight, good sleep, avoiding smoking, and managing stress can help naturally control blood pressure. Seek urgent medical care if you develop severe headache, chest pain, breathing difficulty, weakness, blurred vision, or very high blood pressure readings.
health query

Have a query?

How Soon It Starts Working

  • The time required for Espin AT Tablet to start to work: The time required for Espin AT Tablet to show its action is unknown.
  • The time for which the effects of Espin AT Tablet last: The duration of action for Espin AT Tablet is clinically unknown.

What if you forget to take Espin AT Tablet

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed dose.

Storage

• Store Espin AT Tablet tablets at room temperature, safely between 15°C and 30°C (59°F and 86°F). 

Drug Warnings

  • Never stop taking this medicine suddenly: Doing so can cause a rapid, dangerous rise in blood pressure or trigger severe chest pain and heart complications. Talk to your doctor if you need to stop, as they will guide you in gradually decreasing your dose.
  • Monitor your pulse rate regularly: Check your heart rate weekly. If your pulse consistently falls below 50 beats per minute, contact your doctor for advice.
  • Rise slowly from sitting or lying positions: This medicine can cause dizziness when you stand up quickly. Move slowly to prevent falls or fainting.
  • Be cautious if you have diabetes: Espin AT Tablet can hide the typical warning signs of low blood sugar, such as a fast or pounding heartbeat. Pay close attention to other signs like sweating or shakiness, and monitor your blood sugar regularly.
  • Inform medical professionals before surgeries: Always let your surgeon, dentist, or anaesthesiologist know that you are taking Espin AT Tablet before undergoing any medical procedures.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Espin AT Tablet and affect its safety or effectiveness. Inform your doctor about all the medicines and supplements you are taking before starting treatment. 

  • Other blood pressure drugs: Taking Espin AT Tablet with other medications that lower blood pressure can cause your pressure to drop too low, leading to severe dizziness or fainting.
  • Heart rhythm medicines: Combining this medicine with certain heart medications can cause your heart rate to slow down to dangerous levels.
  • Pain relievers (NSAIDs): Common pain medicines like ibuprofen can reduce the blood pressure-lowering effectiveness of Espin AT Tablet .
S-Amlodipine + AtenololDiltiazem
Severe
S-Amlodipine + AtenololFingolimod
Severe

Drug-Drug Interactions

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S-Amlodipine + AtenololDiltiazem
Severe
How does the drug interact with Espin AT Tablet:
Taking Espin AT Tablet and diltiazem together may lead to increased side effects.

How to manage the interaction:
Taking Espin AT Tablet and diltiazem together can result in an interaction; it can be taken if a doctor has recommended it. However, if you experience tiredness, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest discomfort, increased or reduced heartbeat, or irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting doctor.
S-Amlodipine + AtenololFingolimod
Severe
How does the drug interact with Espin AT Tablet:
Using Espin AT Tablet with fingolimod can result in an abnormally slow heart rate, which can lead to significant heart issues.

How to manage the interaction:
Taking Espin AT Tablet and fingolimod together may result in an interaction, it can be taken if a doctor has recommended it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations during treatment, consult the doctor. Do not discontinue any medications without consulting a doctor.
S-Amlodipine + AtenololTheophylline
Severe
How does the drug interact with Espin AT Tablet:
Using Espin AT Tablet with theophylline, could increase the effects of theophylline.

How to manage the interaction:
Taking Espin AT Tablet and theophylline together can result in an interaction; it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
S-Amlodipine + AtenololVerapamil
Severe
How does the drug interact with Espin AT Tablet:
Taking verapamil with Espin AT Tablet can increase the risk or severity of verapamil side effects.

How to manage the interaction:
Taking Espin AT Tablet and Verapamil together can result in an interaction; it can be taken if a doctor has advised it. However, if you experience, fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
S-Amlodipine + AtenololPhenytoin
Severe
How does the drug interact with Espin AT Tablet:
Co-administration of Phenytoin and Espin AT Tablet can reduce the blood levels of Amlodipine, that may make the medication less effective.

How to manage the interaction:
Co-administration of Phenytoin and Espin AT Tablet can lead to an interaction, but they can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
S-Amlodipine + AtenololAminophylline
Severe
How does the drug interact with Espin AT Tablet:
Coadministration of Espin AT Tablet with aminophylline could certainly reduce the efficacy of atenolol and enhance the effects of aminophylline.

How to manage the interaction:
Taking Espin AT Tablet alongside aminophylline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
S-Amlodipine + AtenololAtazanavir
Severe
How does the drug interact with Espin AT Tablet:
The use of atazanavir with Espin AT Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
The combination of Espin AT Tablet and atazanavir may result in an interaction, it can be taken if a doctor has advised it. However, if you develop sudden dizziness, lightheadedness, fainting, or irregular heartbeat, contact the doctor immediately. Do not stop using any medications without a doctor's advice.
S-Amlodipine + AtenololDisopyramide
Severe
How does the drug interact with Espin AT Tablet:
When disopyramide is used with Espin AT Tablet, it may increase the effects of disopyramide.

How to manage the interaction:
When Espin AT Tablet is used with disopyramide, it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, fainting, heart palpitations, slow or fast pulse, or irregular heartbeats, consult the doctor immediately. Do not stop using any medication without consulting a doctor.
S-Amlodipine + AtenololMitotane
Severe
How does the drug interact with Espin AT Tablet:
Co-administration of Mitotane and Espin AT Tablet can reduce the blood levels of S-Amlodipine.

How to manage the interaction:
Co-administration of Mitotane and Espin AT Tablet can lead to an interaction, but they can be taken if advised by your doctor. Do not stop using any medications without a doctor's advice.
S-Amlodipine + AtenololCarbamazepine
Severe
How does the drug interact with Espin AT Tablet:
Taking carbamazepine and Espin AT Tablet together may possibly reduce the blood levels of S-Amlodipine, which could reduce its treatment outcomes.

How to manage the interaction:
Although taking Carbamazepine and Espin AT Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop taking any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

The following foods and drinks may influence how Espin AT Tablet works in your body.

  • Grapefruit and grapefruit juice: Grapefruit can increase the blood levels of S-amlodipine by affecting the enzyme (CYP3A4) that breaks it down. This may increase the risk of side effects such as dizziness, flushing, or low blood pressure. It does not significantly affect atenolol.
  • Large amounts of caffeine: Excessive caffeine intake may cause a temporary increase in blood pressure in some people. Moderate tea or coffee consumption is generally acceptable for most patients, but discuss your intake with your doctor if you have poorly controlled hypertension.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Espin AT Tablet is used to treat hypertension (high blood pressure).
Espin AT Tablet consists of Atenolol and S-Amlodipine. Atenolol treats high blood pressure, angina (chest pain), and irregular heartbeats (arrhythmias) by reducing heart rate and improving blood flow throughout the body. S-Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering the blood pressure.
Espin AT Tablet is recommended to use in the dose and duration as advised by your doctor. Do not stop taking Espin AT Tablet on your own, as it may lead to a sudden rise in blood pressure, which increases the risk of heart attack and stroke.
Espin AT Tablet can cause dizziness as a side effect. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.
Espin AT Tablet may alter blood glucose levels because beta-blockers (blood pressure-lowering agents) such as Atenolol can mask hypoglycaemic symptoms (low blood glucose). Please consult your doctor for more information.
Although your blood pressure returns to normal after using Espin AT Tablet , it may increase again if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and resume your regular dosing schedule.
Espin AT Tablet should be used with caution in people with kidney diseases. The doctor may adjust the dose based on the medical conditions of the affected person.
No, Espin AT Tablet is not habit-forming medicine. However, take Espin AT Tablet as advised by the doctor. Do not exceed the recommended dose.
Espin AT Tablet should be used with caution in people with liver diseases. The doctor may adjust dose based on the medical conditions of the affected person.
The side effects of Espin AT Tablet include nausea, headache, dizziness, tiredness, sleepiness, swelling of the ankles or feet, cold hands or feet, constipation or stomach upset. If these side effects persist or worsen, please, consult your doctor.
Espin AT Tablet shows its full effect within 2 to 4 weeks of consistent use. If you have any concerns, discuss with your doctor.
Itching is not a common side effect of Espin AT Tablet . However, if you experience itching while taking Espin AT Tablet , contact your doctor immediately.
Take Espin AT Tablet as advised by your doctor. But try to take it at the same time every day. Follow your doctor’s instructions.
Although serious side effects are rare, if you experience them, you should consult your doctor immediately. These include chest pain, very low blood pressure, fainting and irregular heartbeat.
No, you should never stop taking Espin AT Tablet without consulting your doctor. High blood pressure often has no visible symptoms, and stopping the medicine suddenly can cause a dangerous spike in blood pressure. Talk to your doctor before making any changes.
Dizziness is common, especially when first starting this medicine. Avoid standing up too quickly from a sitting or lying position, and rest if you feel lightheaded. If the dizziness persists or becomes severe, talk to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can increase the blood pressure-lowering effect of Espin AT Tablet , which may lead to extreme dizziness, lightheadedness, or fainting. Talk to your doctor.
Swelling in the ankles or lower legs is a known side effect of one of the active components in this medicine, which relaxes blood vessels and can cause fluid to pool. If the swelling is severe or painful, talk to your doctor.
Espin AT Tablet is generally not recommended during pregnancy unless your doctor considers it essential. Atenolol has been associated with reduced fetal growth, low birth weight, and slow heart rate (bradycardia) or low blood sugar in newborns when used during pregnancy. If you are pregnant, planning to become pregnant, or think you may be pregnant, contact your doctor promptly to discuss safer treatment options.
Yes, you should avoid eating grapefruit or drinking grapefruit juice while taking Espin AT Tablet . Grapefruit can increase the amount of S-amlodipine (one of the active ingredients) in your bloodstream by slowing its breakdown, which may increase the risk of side effects such as dizziness or low blood pressure. Atenolol is not significantly affected by grapefruit.
Yes, this is a common side effect of this medicine. It works by slowing your heart rate and altering blood flow, which can sometimes reduce circulation to your extremities. If this becomes highly uncomfortable, talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ESP0010
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