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compositionComposition:ATENOLOL-50MG+S AMLODIPINE-2.5MG
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Prescription Medicine
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S-Amlosafe AT Tablet is used to treat hypertension (high blood pressure). It helps relax blood vessels and supports smooth blood flow. This lowers blood pressure and reduces cardiac strain. It reduces the risk of cardiovascular complications and supports heart health.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ATENOLOL-50MG+S AMLODIPINE-2.5MG

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About S-Amlosafe AT Tablet

S-Amlosafe AT Tablet is a combination medicine prescribed to treat high blood pressure (hypertension). By lowering high blood pressure, this medicine helps prevent future heart attacks, strokes, and kidney problems. It is designed to keep your cardiovascular system running smoothly and safely.

For the best results, you should take S-Amlosafe AT Tablet once daily at the same time each day. You can take this medicine with or without food, but consistency is key to keeping your blood pressure stable. Along with taking this medication, adopting a heart-healthy diet low in salt and staying active will greatly improve your treatment outcomes.

While taking S-Amlosafe AT Tablet , some people may experience mild side effects like drowsiness, headaches, or cold hands and feet. However, if you notice serious issues such as an unusually slow heart rate, severe dizziness, or swelling in your ankles, you should contact your doctor immediately. Do not ignore these signs, as they require professional medical evaluation.

Before starting S-Amlosafe AT Tablet , tell your doctor if you have a history of asthma, lung disease, or severe blood circulation issues. Do not take this if you have certain heart conditions, such as a very slow heart rate or serious heart block. Always share your complete medical history with your healthcare provider to ensure this medication is safe for you.

This medicine can interact with alcohol, which may cause a sudden drop in your blood pressure and increase dizziness. Smoking damages blood vessels and increases your risk of heart disease, stroke, and high blood pressure. Quitting smoking can improve your overall cardiovascular health and support the benefits of your blood pressure treatment. If you are pregnant, planning to breastfeed, or are an elderly individual, talk to your doctor or pharmacist before using this medicine to weigh the benefits and risks.

Uses of S-Amlosafe AT Tablet

The following are the common conditions for which S-Amlosafe AT Tablet is prescribed: 

  • High blood pressure (Hypertension): S-Amlosafe AT Tablet helps by relaxing and widening your blood vessels, making it easier for blood to flow and lowering the overall pressure in your cardiovascular system.
  • Angina (chronic chest pain): By reducing the workload on your heart and improving blood flow, S-Amlosafe AT Tablet helps prevent chest pain caused by reduced blood flow to the heart muscle.

Key Benefits

The following benefits highlight how S-Amlosafe AT Tablet helps control blood pressure, protect your heart, and improve your daily quality of life:

  • Provides effective blood pressure control: It helps maintain healthy blood pressure levels, reducing strain on the heart and blood vessels.
  • Reduces the risk of cardiovascular complications: Long-term blood pressure control helps lower the risk of serious complications such as heart attack, stroke, and kidney damage.
  • Prevents angina symptoms: By improving blood flow to the heart and decreasing its workload, it helps reduce the frequency and severity of chest pain, allowing you to remain more physically active.
  • Offers convenient combination therapy: Combining two medicines with complementary actions into a single tablet simplifies treatment and may improve adherence to your prescribed medication regimen.

Directions for Use

  • S-Amlosafe AT Tablet can be taken with or without food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow S-Amlosafe AT Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How S-Amlosafe AT Tablet Works

S-Amlosafe AT Tablet contains two active medicines that work together to lower blood pressure and reduce the workload on your heart. S-Amlodipine is a calcium channel blocker that primarily relaxes the smooth muscle in blood vessel walls by reducing calcium entry into these cells. This widens the blood vessels, improves blood flow, and lowers blood pressure. It also has a smaller effect on the heart, helping reduce its workload. Atenolol is a cardioselective (beta-1 selective) beta-blocker. It reduces the effects of adrenaline mainly on the heart, slowing the heart rate and reducing the force of contraction. This lowers blood pressure and decreases the heart's workload.  Together, these medicines help control high blood pressure, improve blood flow, reduce strain on the heart, and lower the risk of complications such as heart attack and stroke.
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Alcohol

Unsafe

Alcohol may lower your blood pressure. It would help if you avoid or limit consuming alcohol whilst taking this medicine.

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Pregnancy

Caution

S-Amlosafe AT Tablet is not recommended during pregnancy since it may have harmful effects on the unborn baby. However, it is advised to seek medical advice before using S-Amlosafe AT Tablet if you plan to conceive or already pregnant.

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Breast Feeding

Caution

S-Amlosafe AT Tablet is not recommended during breastfeeding since it may pass into the breast milk. Please consult your doctor before using S-Amlosafe AT Tablet if you are a lactating mother.

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Driving

Unsafe

S-Amlosafe AT Tablet may cause side effects due to a reduction in blood pressure, such as dizziness or fatigue. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using S-Amlosafe AT Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using S-Amlosafe AT Tablet .

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Children

Unsafe

S-Amlosafe AT Tablet is not recommended for use by people under 18.

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Heart

Caution

S-Amlosafe AT Tablet should be used with caution in patients with cardiovascular disease. Therefore, please inform your doctor before using S-Amlosafe AT Tablet .

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Geriatrics

Caution

S-Amlosafe AT Tablet should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of S-Amlosafe AT Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of S-Amlosafe AT Tablet

If you suspect an overdose, seek immediate medical attention or contact a poison control centre right away. Symptoms of an overdose may include extreme dizziness, fainting, an exceptionally slow heartbeat, or severe weakness.

Diet & Lifestyle Advise

  • Reduce salt intake: Limit your daily sodium intake by avoiding processed foods and not adding extra salt to your meals, which directly helps lower blood pressure.
  • Eat a heart-healthy diet: Focus on meals rich in whole grains, fruits, vegetables, lean proteins, and low-fat dairy products.
  • Engage in regular exercise: Aim for at least 30 minutes of moderate physical activity, like brisk walking, most days of the week. Talk to your doctor before starting any new exercise routine.
  • Limit alcohol and quit smoking: Avoid smoking completely as nicotine damages blood vessels, and limit alcohol consumption to prevent sudden blood pressure changes.
health query

Have a query?

How Soon It Starts Working

  • The time required for S-Amlosafe AT Tablet to start to work: The time required for S-Amlosafe AT Tablet to show its action is unknown.
  • The time for which the effects of S-Amlosafe AT Tablet last: The duration of action for S-Amlosafe AT Tablet is clinically unknown.

What if you forget to take S-Amlosafe AT Tablet

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed dose.

Storage

• Store S-Amlosafe AT Tablet tablets at room temperature, safely between 15°C and 30°C (59°F and 86°F). 

Drug Warnings

  • Never stop taking this medicine suddenly: Doing so can cause a rapid, dangerous rise in blood pressure or trigger severe chest pain and heart complications. Talk to your doctor if you need to stop, as they will guide you in gradually decreasing your dose.
  • Monitor your pulse rate regularly: Check your heart rate weekly. If your pulse consistently falls below 50 beats per minute, contact your doctor for advice.
  • Rise slowly from sitting or lying positions: This medicine can cause dizziness when you stand up quickly. Move slowly to prevent falls or fainting.
  • Be cautious if you have diabetes: S-Amlosafe AT Tablet can hide the typical warning signs of low blood sugar, such as a fast or pounding heartbeat. Pay close attention to other signs like sweating or shakiness, and monitor your blood sugar regularly.
  • Inform medical professionals before surgeries: Always let your surgeon, dentist, or anaesthesiologist know that you are taking S-Amlosafe AT Tablet before undergoing any medical procedures.

verifiedApollotooltip

The following medicines may interact with S-Amlosafe AT Tablet and affect its safety or effectiveness. Inform your doctor about all the medicines and supplements you are taking before starting treatment. 

  • Other blood pressure drugs: Taking S-Amlosafe AT Tablet with other medications that lower blood pressure can cause your pressure to drop too low, leading to severe dizziness or fainting.
  • Heart rhythm medicines: Combining this medicine with certain heart medications can cause your heart rate to slow down to dangerous levels.
  • Pain relievers (NSAIDs): Common pain medicines like ibuprofen can reduce the blood pressure-lowering effectiveness of S-Amlosafe AT Tablet .

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verifiedApollotooltip

The following foods and drinks may influence how S-Amlosafe AT Tablet works in your body.

  • Grapefruit and grapefruit juice: Grapefruit can increase the blood levels of S-amlodipine by affecting the enzyme (CYP3A4) that breaks it down. This may increase the risk of side effects such as dizziness, flushing, or low blood pressure. It does not significantly affect atenolol.
  • Large amounts of caffeine: Excessive caffeine intake may cause a temporary increase in blood pressure in some people. Moderate tea or coffee consumption is generally acceptable for most patients, but discuss your intake with your doctor if you have poorly controlled hypertension.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

S-Amlosafe AT Tablet is used to treat hypertension (high blood pressure).
S-Amlosafe AT Tablet consists of Atenolol and S-Amlodipine. Atenolol treats high blood pressure, angina (chest pain), and irregular heartbeats (arrhythmias) by reducing heart rate and improving blood flow throughout the body. S-Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering the blood pressure.
S-Amlosafe AT Tablet is recommended to use in the dose and duration as advised by your doctor. Do not stop taking S-Amlosafe AT Tablet on your own, as it may lead to a sudden rise in blood pressure, which increases the risk of heart attack and stroke.
S-Amlosafe AT Tablet can cause dizziness as a side effect. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.
S-Amlosafe AT Tablet may alter blood glucose levels because beta-blockers (blood pressure-lowering agents) such as Atenolol can mask hypoglycaemic symptoms (low blood glucose). Please consult your doctor for more information.
Although your blood pressure returns to normal after using S-Amlosafe AT Tablet , it may increase again if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and resume your regular dosing schedule.
S-Amlosafe AT Tablet should be used with caution in people with kidney diseases. The doctor may adjust the dose based on the medical conditions of the affected person.
No, S-Amlosafe AT Tablet is not habit-forming medicine. However, take S-Amlosafe AT Tablet as advised by the doctor. Do not exceed the recommended dose.
S-Amlosafe AT Tablet should be used with caution in people with liver diseases. The doctor may adjust dose based on the medical conditions of the affected person.
The side effects of S-Amlosafe AT Tablet include nausea, headache, dizziness, tiredness, sleepiness, swelling of the ankles or feet, cold hands or feet, constipation or stomach upset. If these side effects persist or worsen, please, consult your doctor.
S-Amlosafe AT Tablet shows its full effect within 2 to 4 weeks of consistent use. If you have any concerns, discuss with your doctor.
Itching is not a common side effect of S-Amlosafe AT Tablet . However, if you experience itching while taking S-Amlosafe AT Tablet , contact your doctor immediately.
Take S-Amlosafe AT Tablet as advised by your doctor. But try to take it at the same time every day. Follow your doctor’s instructions.
Although serious side effects are rare, if you experience them, you should consult your doctor immediately. These include chest pain, very low blood pressure, fainting and irregular heartbeat.
No, you should never stop taking S-Amlosafe AT Tablet without consulting your doctor. High blood pressure often has no visible symptoms, and stopping the medicine suddenly can cause a dangerous spike in blood pressure. Talk to your doctor before making any changes.
Dizziness is common, especially when first starting this medicine. Avoid standing up too quickly from a sitting or lying position, and rest if you feel lightheaded. If the dizziness persists or becomes severe, talk to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can increase the blood pressure-lowering effect of S-Amlosafe AT Tablet , which may lead to extreme dizziness, lightheadedness, or fainting. Talk to your doctor.
Swelling in the ankles or lower legs is a known side effect of one of the active components in this medicine, which relaxes blood vessels and can cause fluid to pool. If the swelling is severe or painful, talk to your doctor.
S-Amlosafe AT Tablet is generally not recommended during pregnancy unless your doctor considers it essential. Atenolol has been associated with reduced fetal growth, low birth weight, and slow heart rate (bradycardia) or low blood sugar in newborns when used during pregnancy. If you are pregnant, planning to become pregnant, or think you may be pregnant, contact your doctor promptly to discuss safer treatment options.
Yes, you should avoid eating grapefruit or drinking grapefruit juice while taking S-Amlosafe AT Tablet . Grapefruit can increase the amount of S-amlodipine (one of the active ingredients) in your bloodstream by slowing its breakdown, which may increase the risk of side effects such as dizziness or low blood pressure. Atenolol is not significantly affected by grapefruit.
Yes, this is a common side effect of this medicine. It works by slowing your heart rate and altering blood flow, which can sometimes reduce circulation to your extremities. If this becomes highly uncomfortable, talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - SAM0005
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