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compositionComposition:HYDROCHLOROTHIAZIDE-12.5MG+S AMLODIPINE-2.5MG
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Prescription Medicine
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Espin-H Tablet is used for the treatment of hypertension (high blood pressure). It contains S-Amlodipine and Hydrochlorothiazide, which work by relaxing and widening the blood vessels. Also, it helps to remove extra water and certain electrolytes from the body through urine. Thus, it lowers high blood pressure and reduces the chances of future heart attack and stroke. It may cause side effects such as ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, and decreased potassium level in the blood. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

HYDROCHLOROTHIAZIDE-12.5MG+S AMLODIPINE-2.5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Espin-H Tablet

Espin-H Tablet is a prescription tablet used to treat high blood pressure, also known as hypertension. Its medical purpose is to lower elevated blood pressure to help prevent life-threatening complications such as heart attacks and strokes. This medication is typically prescribed when a single active therapy is not enough to control your blood pressure.

For the best results, you must take Espin-H Tablet consistently once a day, ideally at the same time each day, to maintain steady medicine levels in your body. You can take this tablet with or without food, but it is best to be consistent with your chosen method. Incorporating a low-sodium diet and engaging in regular, moderate exercise will significantly help improve your treatment results.

Some people taking Espin-H Tablet may experience mild side effects, such as ankle swelling, dizziness, or a mild upset stomach. While these symptoms are often temporary, you must consult your doctor immediately if you experience severe side effects, such as chest pain, a rapid or fluttering heart, or severe muscle weakness.

Before starting Espin-H Tablet , talk to your doctor if you have kidney problems, liver damage, or gout. Do not take this medicine if you have severe kidney failure, are unable to urinate, or have a known allergy to any of its components.

This medicine can interact with alcohol, causing an unsafe drop in blood pressure, and smoking can reduce its cardiovascular benefits. Always consult your doctor before using this medicine if you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, as you may require special monitoring.

Uses of Espin-H Tablet

Espin-H Tablet is used in the treatment of Hypertension. The detailed uses of Espin-H Tablet are as follows:

  • High Blood Pressure (Hypertension): Espin-H Tablet relaxes the blood vessels and helps your body eliminate excess salt and fluid, bringing your blood pressure back down to a safer range.
  • Reducing Cardiovascular Risks: By maintaining healthy blood pressure levels, Espin-H Tablet lowers your risk of experiencing serious, life-threatening events like strokes and heart attacks.

Key Benefits

Espin-H Tablet helps lower and control high blood pressure, making it easier to maintain a healthy and active lifestyle. It also helps protect important organs and lowers the risk of serious complications associated with uncontrolled hypertension.

Benefits may include:

  • Helps lower and maintain healthy blood pressure levels.
  • Reduces the risk of heart attack and stroke.
  • Improves long-term heart and blood vessel health.
  • Supports healthy kidney and brain function by controlling blood pressure.
  • Provides convenient blood pressure management with a single daily medicine.

Directions for Use

  • Swallow the medication whole with a full glass of water.
  • Do not chew, crush, or split the tablet, as this can affect how the medicine is absorbed in your body.
  • Take your dose at the same time each day to build a habit and keep a steady level of the medicine in your bloodstream.
  • You may take this medicine with or without food, but choose one way and stick to it consistently.
  • Please remember to follow your doctor's exact instructions regarding your treatment plan. Do not change how you take this medicine without speaking to your doctor first.

How Espin-H Tablet Works

Espin-H Tablet combines two active ingredients that target blood pressure from different angles to achieve a highly effective result. • S Amlodipine: It is a calcium channel blocker that works by stopping calcium from entering the muscle cells of your blood vessels. This action relaxes and widens the blood vessels, allowing blood to flow more freely and reducing the force your heart must use to pump blood throughout your body. • Hydrochlorthiazide: It is a thiazide diuretic, commonly referred to as a water pill. It prompts your kidneys to remove excess water and salt from your bloodstream and release it through your urine. By lowering the overall amount of fluid in your blood vessels, the pressure on the vessel walls decreases.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Espin-H Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Espin-H Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Espin-H Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Unsafe

It is advised to drive with caution after taking Espin-H Tablet as it usually causes drowsiness and affects the driving ability.

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Liver

Caution

Espin-H Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Espin-H Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions

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Children

Caution

Espin-H Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

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Heart

Safe if prescribed

Espin-H Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Espin-H Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Espin-H Tablet

If you accidentally take too much Espin-H Tablet and experience severe dizziness, confusion, fainting, or a racing heartbeat, seek emergency medical care immediately. You can contact your local hospital or a poison control centre for guidance.

Diet & Lifestyle Advise

  • Reduce Salt Intake: Limit your daily sodium intake. Excess salt causes fluid retention, which directly works against the blood pressure-lowering effects of Espin-H Tablet .
  • Incorporate Potassium-Rich Foods: Because the diuretic component of this medication can cause your body to lose potassium, discuss with your doctor whether you should eat more potassium-rich foods like bananas, oranges, and leafy greens.
  • Stay Safely Hydrated: This medicine increases urination. Ensure you drink enough water throughout the day to avoid dehydration, but consult your doctor about the ideal amount of fluid for your specific health condition.
  • Avoid Grapefruit Products: Do not eat grapefruit or drink grapefruit juice while taking Espin-H Tablet . Grapefruit can increase the amount of the amlodipine component of Espin-H Tablet in your body, which may increase the risk of side effects such as dizziness or low blood pressure.
  • Rise Slowly: To minimise dizziness, take your time when standing up from a lying or sitting position. Let your feet rest on the floor for a few moments before fully standing.
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How Soon It Starts Working

  • The time required for Espin-H Tablet to start to work: The time required for Espin-H Tablet to show its action is unknown.
  • The time for which the effects of Espin-H Tablet last: The duration of action for Espin-H Tablet is clinically unknown.

What if you forget to take Espin-H Tablet

If you miss a dose of Espin-H Tablet , take it as soon as you remember. If your next scheduled dose is only a few hours away, skip the missed dose entirely and resume your regular schedule. Do not take two doses at the same time to make up for a missed tablet.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor Blood Pressure Daily: Use a home blood pressure monitor to track your levels regularly. Keep a written log of your readings to share with your doctor during check-ups.
  • Limit Alcohol Consumption: Avoid drinking alcohol while taking Espin-H Tablet , as it can severely drop your blood pressure and cause severe dizziness, drowsiness, or fainting.
  • Wear Sunscreen: This medication can make your skin more sensitive to sunlight. Wear protective clothing and apply a broad-spectrum sunscreen when spending time outdoors to prevent sunburns or skin changes.
  • Watch for Signs of Dehydration: If you experience severe vomiting, diarrhoea, or heavy sweating, contact your doctor, as these conditions can lead to severe dehydration and unsafe blood pressure drops.
  • Before Surgery: Tell your surgeon, dentist, or anaesthetist that you are taking Espin-H Tablet before any planned surgery or medical procedure. Your doctor may advise temporarily stopping or adjusting the medication depending on the type of procedure and your overall health.

verifiedApollotooltip
  • Other Blood Pressure Medications (e.g., enalapril, losartan): Combining Espin-H Tablet with other drugs that lower blood pressure can cause your pressure to drop too low, resulting in severe dizziness or fainting.
  • Mood stabilisers (e.g., lithium): Espin-H Tablet can reduce the kidneys' ability to clear lithium from your body, which may increase the risk of lithium toxicity.
  • Nonsteroidal Anti-inflammatory Drugs (e.g., ibuprofen, naproxen): Painkillers such as ibuprofen or naproxen may decrease the blood pressure-lowering effectiveness of Espin-H Tablet and increase your risk of kidney damage.
  • Potassium Supplements or Potassium-Sparing Medicines (e.g., potassium chloride, spironolactone): Taking these medicines alongside Espin-H Tablet may affect potassium levels in the blood and may require closer monitoring.

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verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Grapefruit may increase the levels of the amlodipine component of Espin-H Tablet , which can increase the risk of side effects such as dizziness or low blood pressure.
  • Alcohol: Consuming alcohol can dangerously enhance the blood pressure-lowering effect of Espin-H Tablet , causing extreme lightheadedness or fainting.

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Espin-H Tablet is used to treat high blood pressure. It works by relaxing the blood vessels, improving blood flow and lowering fluid retention.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
In case, If you forget to take Espin-H Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
Espin-H Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
Yes, Espin-H Tablet may cause swelling of ankle and feet, it is advised to not sit for a long time, and keep the feet up when sitting or lying down.
Espin-H Tablet should be taken in the morning with or without food as prescribed by the doctor, as it contains chlorothiazide, a diuretic that increases urination. So, morning doses help to prevent frequent urination at night, which could disturb your sleep.
You can take other supplements for controlling blood pressure along with Espin-H Tablet only if prescribed by the doctor. Consult the doctor before taking Espin-H Tablet with supplements.
Nausea is a common side effect caused by Espin-H Tablet . If you experience nausea drink ginger or peppermint tea, stay hydrated, eat small, frequent meals and get fresh air.
Regular monitoring of heart rate, blood pressure, breathing and oxygen levels and electrolytes are advised in order to ensure Espin-H Tablet is working effectively and to detect any potential side effects early while taking Espin-H Tablet .
If you are having trouble remembering to take Espin-H Tablet , link your medication doses with daily activity, use alarms to notify the time, use a pill organiser and create a routine by taking your medication at the same time every day.
The side effects of Espin-H Tablet include ankle swelling, oedema, tiredness, fatigue nausea, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, and decreased potassium levels in the blood. Consult the doctor if any of these side effects persist or worsen.
Espin-H Tablet is generally not recommended during pregnancy unless your doctor determines it is clearly needed. The hydrochlorothiazide component may increase the risk of problems such as neonatal jaundice, low platelet counts, or electrolyte disturbances, while there is limited safety information for amlodipine during pregnancy. If you become pregnant while taking this medication, contact your doctor promptly to discuss the safest treatment option.
One of the active ingredients in Espin-H Tablet is a mild diuretic, or water pill, which prompts your kidneys to filter out excess water and salt. This naturally increases the frequency of urination, especially when you first start the medication. To avoid waking up at night, try taking your dose in the morning. Talk to your doctor if this becomes problematic.
You should avoid or strictly limit alcohol consumption while taking Espin-H Tablet . Alcohol can combine with the medication to cause a sharp, unsafe drop in your blood pressure, leading to extreme dizziness, drowsiness, or fainting. Talk to your doctor if you have questions about alcohol use.
Espin-H Tablet can cause dizziness or fatigue, particularly when you first start taking it or after a dose adjustment. Do not drive, ride a bicycle, or operate machinery until you are certain how this medication affects your alertness. Talk to your doctor if you experience persistent dizziness.
Mild swelling in the ankles and feet is a known side effect of this medication. Elevating your legs when sitting can help alleviate this symptom. However, if the swelling is sudden, painful, or accompanied by breathing difficulties, you should talk to your doctor immediately.
Yes, the diuretic component in Espin-H Tablet can cause your body to lose potassium through your urine. Your doctor may perform routine blood tests to check your potassium levels and might suggest specific dietary changes or supplements if your levels drop too low. Talk to your doctor if you experience severe muscle cramps or unexplained weakness.
Yes. Your doctor may recommend periodic blood tests while you are taking Espin-H Tablet to monitor your potassium and other electrolyte levels, kidney function (such as creatinine and eGFR), and, if needed, uric acid or blood sugar levels. These tests help ensure the medicine is working safely and allow your doctor to adjust your treatment if necessary.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ESP0014
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