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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Estolo-650 Tablet 10's is used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headaches, migraines, toothaches, period pain, back pain, muscle pain, and rheumatic pains. It contains Paracetamol, which works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reduces pain. Also, it affects an area of the brain that regulates body temperature, known as the hypothalamic heat-regulating centre. Thereby, it reduces fever. In some cases, it may cause side effects such as nausea, stomach pain and dark-coloured urine.

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Composition :

PARACETAMOL-650MG

Manufacturer/Marketer :

Esteve Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Estolo-650 Tablet 10's

Estolo-650 Tablet 10's is used to reduce fever and treat mild to moderate pain. It is also used to relieve headaches, migraine, toothaches, period pain, back pain, muscle pain, and rheumatic pain. The activation of pain receptors causes pain and fever due to the release of certain natural chemicals in the body, like prostaglandin.

Estolo-650 Tablet 10's works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, reducing pain. Additionally, Estolo-650 Tablet 10's affects an area of the brain that regulates body temperature, known as the hypothalamic heat-regulating centre, which reduces fever.

Not everyone who is taking Estolo-650 Tablet 10's will get these side effects. In some cases, Estolo-650 Tablet 10's may cause side effects such as nausea, stomach pain and dark-coloured urine. Most of these side effects of Estolo-650 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Take Estolo-650 Tablet 10's as advised by your physician. Your doctor will recommend how often you should take Estolo-650 Tablet 10's, based on your medical condition. You can take Estolo-650 Tablet 10's with or without food. It is recommended not to exceed the recommended dose of Estolo-650 Tablet 10's. Do not chew, crush, or break the medicine.

Avoid taking Estolo-650 Tablet 10's if allergic to it. If you are pregnant or breastfeeding, please consult a physician before using Estolo-650 Tablet 10's. Avoid alcohol consumption with Estolo-650 Tablet 10's as it may increase the risk of liver damage. Let your doctor know if you have an impaired nutritional state caused by anorexia (eating disorder), malnutrition or alcohol abuse or if you are dehydrated before taking Estolo-650 Tablet 10's.

Uses of Estolo-650 Tablet 10's

Estolo-650 Tablet 10's is used for fever and pain relief. The detailed uses of Estolo-650 Tablet 10's are as follows:

  • Pain Relief: Estolo-650 Tablet 10's is commonly used to treat mild to moderate pain, including headaches, toothaches, muscle aches, and menstrual cramps. It works by suppressing the brain's production of prostaglandins, which induce pain.
  • Fever Reduction: Estolo-650 Tablet 10's effectively reduces fever caused by infections or other conditions. It lowers the body's temperature by working on the hypothalamic heat-regulating area.
  • Cold and Flu Symptom Relief: Estolo-650 Tablet 10's is also used to treat cold and flu symptoms such as body pains, fever, and headaches.
  • Post-Surgery Pain Management: Estolo-650 Tablet 10's is used to treat post-surgery pain, especially when it is mild to moderate, as an alternative to heavier pain drugs.
  • Arthritis-related Pain: Estolo-650 Tablet 10's is used to treat joint pain and discomfort caused by osteoarthritis and rheumatoid arthritis, reducing pain and inflammation.

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Directions for Use

  • Estolo-650 Tablet 10's can be taken with or without food anytime.
  • It is usually taken every 4-6 hours or as suggested by your doctor.
  • Swallow Estolo-650 Tablet 10's as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Estolo-650 Tablet 10's contains Paracetamol, an analgesic (pain killer) and antipyretic (reduces fever).
  • Estolo-650 Tablet 10's affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre, reducing fever.
  • It is one of the most used OTC medicine for reducing pain and fever.

How Estolo-650 Tablet 10's Works

Estolo-650 Tablet 10's works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, reducing pain. Also, Estolo-650 Tablet 10's affects an area of the brain that regulates body temperature, known as the hypothalamic heat-regulating centre, reducing fever.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Estolo-650 Tablet
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

What if I have taken an overdose of Estolo-650 Tablet 10's

Do not take more than the suggested dose of Estolo-650 Tablet 10's as it may cause overdose resulting in the increased risk of delayed, serious liver damage. The symptoms of overdose include vomiting, nausea, diarrhoea, stomach pain and loss of appetite. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Estolo-650 Tablet 10's if allergic to it.
  • Estolo-650 Tablet 10's is not recommended for children below 6 years of age as the safety and efficacy are not established.
  • If you are pregnant or breastfeeding, please consult a physician before using Estolo-650 Tablet 10's.
  • Avoid alcohol consumption with Estolo-650 Tablet 10's as it may increase the risk of liver damage.
  • If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Estolo-650 Tablet 10's.
  • Avoid taking more than the recommended doses, as it may increase the risk of serious liver damage.
  • If you have a high fever or signs of infection after using Estolo-650 Tablet 10's for more than 3 days or if pain persists after using Estolo-650 Tablet 10's for more than 5 days, please consult a physician.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Estolo-650 Tablet:
Co-administration of ketamine and Estolo-650 Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Estolo-650 Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Estolo-650 Tablet:
Co-administration of Estolo-650 Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Estolo-650 Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Estolo-650 Tablet:
Co-administration of Estolo-650 Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Estolo-650 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Estolo-650 Tablet:
Co-administration of Teriflunomide with Estolo-650 Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Estolo-650 Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Estolo-650 Tablet:
Co-administration of Mipomersen with Estolo-650 Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Estolo-650 Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Estolo-650 Tablet:
Co-administration of Estolo-650 Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Estolo-650 Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Estolo-650 Tablet:
Co-administration of Lomitapide and Estolo-650 Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Estolo-650 Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Estolo-650 Tablet:
Co-administration of Estolo-650 Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Estolo-650 Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and regularly apply a cold or hot compress on the joints for 15-20 minutes.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids, such as soy, berries, broccoli, grapes, and green tea, help reduce inflammation.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Estolo-650 Tablet 10's as it may cause severe liver damage.

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Pregnancy

Consult your doctor

Please consult a physician if you are pregnant or planning for pregnancy before using this medicine. Your physician may suggest the lowest dose of Paracetamol for the shortest duration if you are pregnant.

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Breast Feeding

Consult your doctor

Estolo-650 Tablet 10's may be excreted in small amounts in breast milk. Therefore, please consult a physician before using this medicine if you are breastfeeding.

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Driving

Safe if suggested

Estolo-650 Tablet 10's usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Estolo-650 Tablet 10's with caution, especially if you have a history of liver disease. Your physician may adjust the dose as required.

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Kidney

Caution

Take Estolo-650 Tablet 10's with caution, especially if you have a history of kidney disease. Your physician may adjust the dose as needed.

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Children

Consult your doctor

Please consult a doctor. Your doctor will prescribe a suitable dose of Estolo-650 Tablet 10's based on the age, body weight and condition of your child.

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Heart

Safe if suggested

Estolo-650 Tablet 10's is generally considered safe for heart patients when used at recommended doses. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if suggested

Estolo-650 Tablet 10's is considered safe for elderly patients when taken at recommended doses; however, liver function and total daily dosage should be monitored to prevent toxicity.

FAQs

Estolo-650 Tablet 10's is used to provide relief from fever and mild-to-moderate pain.

Estolo-650 Tablet 10's works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus reducing pain. Also, Estolo-650 Tablet 10's affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.

You are not recommended to take Estolo-650 Tablet 10's with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you are supposed to use these medicines together, you are advised to contact your physician so that the dose may be adjusted appropriately and used safely.

Estolo-650 Tablet 10's may affect how certain tests work, such as blood sugar tests and uric acid tests. Therefore, if you are about to undergo a blood test or any laboratory tests, inform your physician or lab technician that you are taking Estolo-650 Tablet 10's.

You are not recommended to take Estolo-650 Tablet 10's with other paracetamol-containing products as it may cause paracetamol overdose.

Country of origin

India

Manufacturer/Marketer address

Khasra No 417, Johri Gaon, Jakhan Po - Sinola, Rajpur road Dehradun Dehradun UR 248001 IN.
Other Info - EST0252

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