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  3. EVERTOR 5MG TABLET

EVERTOR 5MG TABLET, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
EVERTOR 5MG TABLET is used to treat cancer and to prevent organ rejection. It contains Everolimus which works by stopping cancer cells from reproducing and decreasing the activity of the immune system. In some cases, this medicine may cause side effects such as weakness, infection, cough, diarrhoea, fever, and fatigue. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

EVEROLIMUS-5MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About EVERTOR 5MG TABLET

EVERTOR 5MG TABLET belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

EVERTOR 5MG TABLET contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take EVERTOR 5MG TABLET as prescribed by your doctor. You are advised to take EVERTOR 5MG TABLET for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of EVERTOR 5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking EVERTOR 5MG TABLET for as long as your doctor has prescribed. If you are known to be allergic to EVERTOR 5MG TABLET or any other medicines, please tell your doctor. Do not take EVERTOR 5MG TABLET if you are pregnant or planning for pregnancy as EVERTOR 5MG TABLET may harm the unborn baby. EVERTOR 5MG TABLET should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. EVERTOR 5MG TABLET causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of EVERTOR 5MG TABLET

Treatment of Breast cancer, pancreatic cancer, lung cancer and kidney cancer.

Directions for Use

Take EVERTOR 5MG TABLET with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

EVERTOR 5MG TABLET is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. EVERTOR 5MG TABLET travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

How EVERTOR 5MG TABLET Works

EVERTOR 5MG TABLET contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Evertor 5mg Tablet
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.

What if I have taken an overdose of EVERTOR 5MG TABLET

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

If you are known to be allergic to EVERTOR 5MG TABLET or any other medicines, please tell your doctor. EVERTOR 5MG TABLET should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take EVERTOR 5MG TABLET if you have recent surgery, infection and hepatitis B. EVERTOR 5MG TABLET may weaken your immune system, inform your doctor before taking EVERTOR 5MG TABLET. EVERTOR 5MG TABLET may also impair your kidney function. Therefore, monitor your kidney function regularly while taking EVERTOR 5MG TABLET. EVERTOR 5MG TABLET may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your EVERTOR 5MG TABLET. EVERTOR 5MG TABLET may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take EVERTOR 5MG TABLET if you are pregnant or planning for pregnancy as EVERTOR 5MG TABLET may harm the unborn baby. EVERTOR 5MG TABLET should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. EVERTOR 5MG TABLET causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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EverolimusGolimumab
Severe
EverolimusNefazodone
Severe

Drug-Drug Interactions

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EverolimusGolimumab
Severe
How does the drug interact with Evertor 5mg Tablet:
When Evertor 5mg Tablet is used with Golimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Evertor 5mg Tablet and Golimumab, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusNefazodone
Severe
How does the drug interact with Evertor 5mg Tablet:
Taking Evertor 5mg Tablet with nefazodone can considerably raise blood levels of Evertor 5mg Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Co-administration of Evertor 5mg Tablet with Nefazodone can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
EverolimusTofacitinib
Severe
How does the drug interact with Evertor 5mg Tablet:
Taking Tofacitinib and Evertor 5mg Tablet may increase the risk of serious infection.

How to manage the interaction:
Co-administration of Tofacitinib with Evertor 5mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
EverolimusAciclovir
Severe
How does the drug interact with Evertor 5mg Tablet:
Coadministration of Aciclovir with Evertor 5mg Tablet may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Aciclovir with Evertor 5mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, breathing difficulty, muscle pains, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
EverolimusTelaprevir
Severe
How does the drug interact with Evertor 5mg Tablet:
Taking Evertor 5mg Tablet with telaprevir can considerably raise blood levels of Evertor 5mg Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Taking Evertor 5mg Tablet with Telaprevir together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
EverolimusRifapentine
Severe
How does the drug interact with Evertor 5mg Tablet:
When Evertor 5mg Tablet is taken with Rifapentine, it may lower Evertor 5mg Tablet blood levels, making it less effective in treating the illness.

How to manage the interaction:
Taking Evertor 5mg Tablet with Rifapentine together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EverolimusNaproxen
Severe
How does the drug interact with Evertor 5mg Tablet:
Coadministration of Naproxen and Evertor 5mg Tablet can increase the risk or severity of kidney problems

How to manage the interaction:
Taking Naproxen and Evertor 5mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.
Everolimusvalacyclovir
Severe
How does the drug interact with Evertor 5mg Tablet:
Co-administration of Evertor 5mg Tablet with valacyclovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Evertor 5mg Tablet and valacyclovir together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased urination, weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
EverolimusIodamide
Severe
How does the drug interact with Evertor 5mg Tablet:
Injections of Iodamide and related contrast agents can occasionally cause kidney damage, and mixing it with Evertor 5mg Tablet, may enhance the risk.

How to manage the interaction:
Although taking Evertor 5mg Tablet and Iodamide together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.
EverolimusOxaprozin
Severe
How does the drug interact with Evertor 5mg Tablet:
Evertor 5mg Tablet can cause kidney issues, and taking it with other medications that can harm the kidney, such as oxaprozin, can enhance the risk.

How to manage the interaction:
Although taking Evertor 5mg Tablet and Oxaprozin together can cause an interaction, it can be taken if your doctor has suggested it. However, If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult your doctor.

Drug-Food Interactions

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EVEROLIMUS-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUS-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Evertor 5mg Tablet with grapefruit juice can raise blood levels and enhance the effects of Evertor 5mg Tablet. Since the co-administration of Evertor 5mg Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Evertor 5mg Tablet.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

EVERTOR 5MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking EVERTOR 5MG TABLET to avoid unpleasant side-effects.

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Pregnancy

Unsafe

EVERTOR 5MG TABLET is belonging to pregnancy C category. It is not safe in pregnancy as it may causes harm to the unborn baby. Do not conceive a baby while taking EVERTOR 5MG TABLET.

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Breast Feeding

Unsafe

EVERTOR 5MG TABLET should not be taken by breastfeeding mothers as it may harm to the new-born baby.

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Driving

Caution

EVERTOR 5MG TABLET may cause tiredness (fatigue), do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

EVERTOR 5MG TABLET should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

bannner image

Kidney

Caution

EVERTOR 5MG TABLET is likely unsafe in patients with severe kidney disease as it may cause kidney failure which can be dangerous, use EVERTOR 5MG TABLET only when prescribed by a doctor.

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Children

Unsafe

EVERTOR 5MG TABLET is not recommended for children below 18 years as the safety and effectiveness were not established.

Have a query?

FAQs

EVERTOR 5MG TABLET is used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer.

EVERTOR 5MG TABLET is an anticancer medicine. It belongs to a group of medicines known as a kinase inhibitor. It works by lowering the blood supply to the tumor, which reduces the growth and spread of cancer cells.

There is no specific duration of treatment with EVERTOR 5MG TABLET. EVERTOR 5MG TABLET is continued till benefit is seen or undesirable toxicity or side effects occur.

You should prevent grapefruit or grapefruit juice while taking EVERTOR 5MG TABLET. This is because taking them together may rise the levels of EVERTOR 5MG TABLET in your blood to toxic levels. Avoid the use of live vaccinations and any probable contact with people who have received live vaccinations.

EVERTOR 5MG TABLET can lead to serious side effects that consist of severe allergic reactions, angioedema (painless swelling under the skin) and kidney failure which can be dangerous and can lead to death. It is possible that you may develop an infection or problems associated to lungs like breathing problems.

It usually takes three to six months for most types of lung cancer to double their size. It will take a long time for lung cancer to reach a size that could be diagnosed in X-Ray.

EVERTOR 5MG TABLET contains Everolimus, which belongs to the group of medicines known as kinase inhibitors.

Regular monitoring is essential when using EVERTOR 5MG TABLET. Your doctor may check your blood tests, blood sugar, blood pressure, and kidney function. They may also adjust your dose based on your response to treatment or any side effects that occur. It's essential to report any changes or concerns to your doctor to ensure safe and effective treatment.

While taking EVERTOR 5MG TABLET, avoiding certain things is essential to ensure your safety. Avoid consuming grapefruit juice and products and St. John's Wort, as they can interact with the medication. Certain antibiotics, antifungals, and medications can also interact with Everolimus, so consult your doctor before taking any new medications. Additionally, consult your doctor before receiving any vaccinations and avoid high-risk activities that may increase the risk of infections and bleeding. It's also important to avoid getting pregnant or fathering a child while taking Everolimus, as well as breastfeeding. Finally, limit your sun exposure to avoid increasing the risk of skin cancer. Always consult your doctor or pharmacist for a comprehensive list of medications and activities to avoid while taking Everolimus.

Before using any medication, including EVERTOR 5MG TABLET, you should know its purpose, usage, safety profile, precautions, and limitations.

EVERTOR 5MG TABLET is administered orally in the form of a tablet. Take Everolimus with or without food, as advised by your doctor. Swallow the tablet whole with water; do not crush, break, or chew it. Note: It's important to follow your doctor's instructions and take EVERTOR 5MG TABLET exactly as prescribed

By regularly monitoring your progress through brain scans and other evaluations, your doctor can determine if EVERTOR 5MG TABLET is effectively shrinking your brain tumor.

EVERTOR 5MG TABLET is indeed considered a cytotoxic medication, but it's a targeted therapy that specifically targets cancer cells and inhibits their growth. It's not a traditional chemotherapy medication, but it can still have side effects and be harmful to healthy cells to some extent. If you have any concerns or questions, please consult your doctor or healthcare team to discuss potential risks and benefits and manage any side effects.

Common side effects of EVERTOR 5MG TABLET may include weakness, infection, sinus inflammation, cough, diarrhoea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of EVERTOR 5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - EVE0189

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.drugs.com/mtm/everolimus.html
  2. https://www.medicines.org.uk/emc/files/pil.11084.pdf
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