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Reviewed By Veda Maddala , M Pharmacy

Fibroease 25mg Tablet is used in combination with Misoprostol to induce a medical abortion. It is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help. It contains Mifepristone, which works by blocking the effect of progesterone (female hormone), needed to sustain a pregnancy. In some cases, you may experience side effects such as nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

MIFEPRISTONE-25MG

Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Fibroease 25mg Tablet

Fibroease 25mg Tablet belongs to the class of medication called 'progestin antagonist' used in combination with Misoprostol to induce a medical abortion. Fibroease 25mg Tablet is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.

Fibroease 25mg Tablet contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Fibroease 25mg Tablet to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete.

Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (which may last up to 30 days), fever, and digestive system discomfort. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised.

Fibroease 25mg Tablet should be taken in dose and duration as advised by the doctor, preferably with food. It would be best to take it at a fixed time every day. It is a tablet and should be taken orally with a glass of water. In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Fibroease 25mg Tablet subside with time. But if your vaginal bleeding does not, please visit the doctor immediately, and it requires immediate medical attention.

Fibroease 25mg Tablet should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Fibroease 25mg Tablet if you have or ever had an ectopic pregnancy (when the fetus grows in the fallopian tube), using an intrauterine device, or if you are breastfeeding, any bleeding disorder or heart problem. Do not do strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.

Uses of Fibroease 25mg Tablet

Fibroease 25mg Tablet is used for Medical abortion. The detailed uses of Fibroease 25mg Tablet are as follows:
•Medical Abortion: Fibroease 25mg Tablet is used to terminate early pregnancies by blocking progesterone, typically up to 49 days from the last menstrual period.
•Combined Therapy: Fibroease 25mg Tablet is often used in combination with misoprostol to complete the abortion process.
•Cushing’s Syndrome Treatment: Fibroease 25mg Tablet is used to treat Cushing's Syndrome by helping to manage excess cortisol levels.
•Regulation of the Menstrual Cycle: To regulate a delayed menstrual cycle, Fibroease 25mg Tablet can be used, but medical supervision is necessary to reduce the risk of side effects.
•Preventing Ovulation: Fibroease 25mg Tablet inhibits or delays ovulation which is necessary for making it an effective emergency contraceptive.

Directions for Use

Fibroease 25mg Tablet should be taken in dose and duration as prescribed by your doctor. Do not chew or crush it; swallow it as a whole.

Medicinal Benefits

Fibroease 25mg Tablet contains Mifepristone, which is taken in a regimen with Misoprostol to induce medical abortion or terminate a pregnancy before 70 days. It works by blocking the effect of progesterone (female hormone) needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Fibroease 25mg Tablet to show effect.

How Fibroease 25mg Tablet Works

Fibroease 25mg Tablet contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fibroease 25mg Tablet

  • Weakness

  • Nausea

  • Uterine cramps

  • Vomiting

  • Diarrhoea

  • Dizziness

  • Infection following abortion

  • Uterine bleeding

What if I have taken an overdose of Fibroease 25mg Tablet

Do not take more than the prescribed dose of Fibroease 25mg Tablet as it may cause overdose. The symptoms of overdose include severe vaginal bleeding. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Women who have an ectopic pregnancy (a pregnancy outside of the uterus, problems with the adrenal glands (the glands near the kidneys), currently taking corticosteroid therapy (medications), have an allergic reaction to mifepristone, misoprostol or similar drugs, have bleeding problems or taking the blood-thinning drug (warfarin, clopidogrel, aspirin, heparin etc.) should not use Fibroease 25mg Tablet and contact doctor. After using Fibroease 25mg Tablet if you start feeling sleepy, do not drive or operate heavy machinery. If you use an intrauterine device (IUD), please remove it before taking the Fibroease 25mg Tablet . Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (herbal supplements to treat mild depression) and grapefruit juice should not be taken when taking Fibroease 25mg Tablet as it is known to interact. 

Drug-Drug Interactions

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MifepristoneDihydroergotamine
Critical
MifepristoneBudesonide
Critical

Drug-Drug Interactions

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MifepristoneDihydroergotamine
Critical
How does the drug interact with Fibroease 25mg Tablet:
When Fibroease 25mg Tablet is taken with Dihydroergotamine, it may increase the risk of side effects.

How to manage the interaction:
Taking Dihydroergotamine with Fibroease 25mg Tablet is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneBudesonide
Critical
How does the drug interact with Fibroease 25mg Tablet:
Using Fibroease 25mg Tablet together with budesonide may significantly reduce the effects of budesonide.

How to manage the interaction:
Taking Budesonide with Fibroease 25mg Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
MifepristoneFondaparinux
Critical
How does the drug interact with Fibroease 25mg Tablet:
Using Fibroease 25mg Tablet together with fondaparinux may increase the risk and/or severity of vaginal bleeding in women

How to manage the interaction:
Taking Fondaparinux with Fibroease 25mg Tablet together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MifepristoneEnoxaparin
Critical
How does the drug interact with Fibroease 25mg Tablet:
Combining Fibroease 25mg Tablet with Enoxaparin can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Enoxaparin with Fibroease 25mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MifepristoneFluticasone
Critical
How does the drug interact with Fibroease 25mg Tablet:
Co-administration of Fluticasone with Fibroease 25mg Tablet may make Fluticasone less effective as a therapy.

How to manage the interaction:
Taking Fluticasone with Fibroease 25mg Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
MifepristoneMesoridazine
Critical
How does the drug interact with Fibroease 25mg Tablet:
Co-administration of Mesoridazine with Mefipristone can increase the risk of an abnormal heart rhythm, low potassium levels in the body.

How to manage the interaction:
Taking Mesoridazine with Fibroease 25mg Tablet is not recommended, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
MifepristoneMethylprednisolone
Critical
How does the drug interact with Fibroease 25mg Tablet:
When Methylprednisolone is taken with Fibroease 25mg Tablet, it may decrease the levels of Methylprednisolone, which may be less effective in treating your condition.

How to manage the interaction:
Taking Methylprednisolone with Fibroease 25mg Tablet is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MifepristoneSimvastatin
Critical
How does the drug interact with Fibroease 25mg Tablet:
Combining Fibroease 25mg Tablet with Simvastatin can increase the blood levels of simvastatin, which may increase the risk of side effects.

How to manage the interaction:
Taking Simvastatin with Fibroease 25mg Tablet is not recommended, but can be taken if prescribed by the doctor. If you experience any symptoms, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
MifepristoneTacrolimus
Critical
How does the drug interact with Fibroease 25mg Tablet:
Taking tacrolimus with Fibroease 25mg Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacrolimus with Fibroease 25mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
MifepristoneTriamcinolone
Critical
How does the drug interact with Fibroease 25mg Tablet:
Using Fibroease 25mg Tablet with Triamcinolone can significantly reduce the effects of triamcinolone.

How to manage the interaction:
Taking Triamcinolone with Fibroease 25mg Tablet is not recommended but can be taken if prescribed by a doctor. However, if you notice any unusual symptoms contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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MIFEPRISTONE-25MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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MIFEPRISTONE-25MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may increase the effects of Fibroease 25mg Tablet. Avoid consumption of grape juice while taking Fibroease 25mg Tablet. However, if you experience headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, swelling, and high blood pressure, consult the doctor.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complications.

  • Avoid chronic stress and physical exercise like running, as it might increase vaginal bleeding.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Get an ultrasound to check if the abortion is done completely to avoid unwanted complications.

  • Try to include heart-healthy omega-3 fatty acid-containing foods or drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTIPROGESTERONE

Fibroease 25mg Tablet Substitute

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Alcohol

Unsafe

Alcohol is known to cause excessive drowsiness if taken along with Fibroease 25mg Tablet and increase uterine bleeding.

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Pregnancy

Unsafe

Fibroease 25mg Tablet is used for medical abortion. If taken in pregnancy, it can lead to abortion.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before prescribing Fibroease 25mg Tablet ; your doctor will decide whether Fibroease 25mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Fibroease 25mg Tablet may reduce alertness or induce sleep and dizziness. If you experience these symptoms, don't drive or operate machinery.

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Liver

Caution

Fibroease 25mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Fibroease 25mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Fibroease 25mg Tablet is not recommended for children below the age of 12. The safety and effectiveness of Fibroease 25mg Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Fibroease 25mg Tablet or not.

FAQs

Fibroease 25mg Tablet is used in combination with Misoprostol to induce a medical abortion. Fibroease 25mg Tablet is primarily used to end an early pregnancy (lasting up to 70 days or less than this) or an unwanted pregnancy with medication help.

No, Fibroease 25mg Tablet should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine bleeding.

No, the Fibroease 25mg Tablet is not known to affect any future chances of fertility. Fibroease 25mg Tablet is used for medical abortion.

If you miss a dose of Fibroease 25mg Tablet , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

After taking Fibroease 25mg Tablet , you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.

No, the Fibroease 25mg Tablet does not affect fertility. Use contraception during sexual intercourse as it may lead to unwanted pregnancy if you are not planning it.

Some of the common side effects of Fibroease 25mg Tablet are nausea, weakness, fever/chills, vomiting, headache, diarrhoea, and dizziness.

Fibroease 25mg Tablet contains Mifepristone, which works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the development of the pregnancy is stopped.

No, taking more than the prescribed dose of Fibroease 25mg Tablet will not make it more effective and could be dangerous. Please follow the dosage as prescribed by your doctor to avoid potential side effects or complications.

Please inform your doctor if you have a history of liver disease before using Fibroease 25mg Tablet . The dosage may need to be adjusted by your doctor, as liver impairment can affect how the drug is metabolized.

Swallow Fibroease 25mg Tablet as a whole with water; do not crush or chew it. The doctor will determine the dose based on your condition.

After taking Fibroease 25mg Tablet , you may experience cramping or bleeding in the uterus as the medication works to block the hormone progesterone and prepare your body for the next step in the abortion process. Typically, bleeding begins within 24-48 hours after taking Fibroease 25mg Tablet . It is common to experience other side effects such as nausea, vomiting, diarrhoea, dizziness, or infection following the abortion. Follow-up with your doctor is essential to ensure that the process is complete.

Country of origin

India

Manufacturer/Marketer address

204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India
Other Info - FIB0078

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