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compositionComposition:FLUCYTOSINE-500MG
prescription
Prescription Medicine
info
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Flucyto Tablet is used to treat yeast and fungal infections caused by Candida and/or Cryptococcus. It contains Flucytosine, which works by interfering with the synthesis of fungal protein and DNA. Thereby, it helps treat fungal infections. In some cases, Flucyto Tablet may cause nausea, vomiting, abdominal pain, and diarrhoea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUCYTOSINE-500MG

Manufacturer/Marketer :

Aureate Healthcare

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Flucyto Tablet

Flucyto Tablet is a prescription antifungal medicine used to treat certain serious fungal infections, particularly infections caused by Candida and Cryptococcus. It is often used with another antifungal medicine because using flucytosine alone can allow the fungus to become resistant to treatment.

Take Flucyto Tablet exactly as prescribed and at evenly spaced times. It can be taken with or without food. If a dose requires several capsules, taking the capsules one at a time over about 15 minutes may help reduce nausea or stomach discomfort.

Flucyto Tablet has a narrow therapeutic index, which means the amount needed to treat the infection and the amount that may cause serious side effects are relatively close. Regular blood tests are therefore important to check the amount of medicine in your blood, your blood cell counts, liver function, and kidney function. Your doctor may adjust the dose based on these results.

Common side effects can include nausea, vomiting, diarrhoea, and stomach discomfort. Consult your doctor right away if you develop unusual bruising or bleeding, severe weakness, signs of infection, yellowing of the skin or eyes, or other serious symptoms.

Before starting Flucyto Tablet , tell your doctor if you have kidney problems, liver problems, low blood cell counts, or bone marrow problems. Also tell your doctor about all medicines you take. If you are pregnant, planning a pregnancy, or breastfeeding, discuss this with your doctor before treatment.
 

Uses of Flucyto Tablet

Your doctor may prescribe Flucyto Tablet to help treat certain serious fungal infections:

  • Cryptococcal infections: Helps treat serious infections caused by Cryptococcus, including cryptococcal meningitis (a fungal infection affecting the lining around the brain and spinal cord). It is usually given with another antifungal medicine.
  • Candida infections: Helps treat certain serious infections caused by Candida, particularly when the infection has spread inside the body or affects important organs.
     

Key Benefits

Flucyto Tablet can help control serious fungal infections that may become life-threatening without effective treatmen

Flucyto Tablet can help control serious fungal infections that may become life-threatening without effective treatment.

  • Controls serious fungal infections: Stops susceptible fungi from growing and multiplying, helping bring the infection under control.
  • Supports combination treatment: When used with another antifungal medicine, Flucyto Tablet can improve treatment of certain severe infections, particularly cryptococcal meningitis.
  • Helps treat infections affecting important organs: It can be used against susceptible fungal infections involving areas such as the bloodstream, urinary tract, heart, or nervous system.
     

Directions for Use

  • Take Flucyto Tablet with or without food or as advised by a doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Flucyto Tablet Works

Flucyto Tablet contains flucytosine, an antifungal medicine. It enters susceptible fungal cells and is converted into 5-fluorouracil (5-FU). The fungal cell then uses 5-FU to form other active substances. One of these substances interferes with RNA, which fungi need to make proteins. Another, called 5-fluorodeoxyuridine monophosphate (5-FdUMP), blocks an enzyme needed to make DNA, the genetic material fungi need to grow and reproduce. By disrupting both protein and DNA production, Flucyto Tablet stops susceptible fungi from growing and multiplying.
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Alcohol

Consult your doctor

It is not known whether alcohol interacts with Flucyto Tablet . Please consult the doctor.

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Pregnancy

Caution

Please consult the doctor if you are pregnant. Flucyto Tablet should be used during pregnancy only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Flucytosine passes into breast milk. Do not take Flucyto Tablet if you are breastfeeding.

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Driving

Consult your doctor

It is unknown if Flucyto Tablet affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before taking Flucyto Tablet .

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Kidney

Caution

Flucyto Tablet should be used with caution in patients with impaired kidney function. The doctor may adjust the dose based on your condition.

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Children

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of Flucyto Tablet in children.

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Heart

Caution

Flucyto Tablet should be used with caution in individuals with heart problems due to potential risks like electrolyte imbalance, renal stress, and rare cardiac side effects. Medical supervision and regular monitoring are essential to ensure safe use.

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Geriatrics

Caution

Flucyto Tablet should be used with caution in geriatric patients due to increased risks of renal impairment, hematologic toxicity, and confusion. Close monitoring of kidney, liver, and blood function is essential throughout treatment.

What if I have taken an overdose of Flucyto Tablet

If you take more Flucyto Tablet than prescribed, seek urgent medical attention. Too much flucytosine can increase the risk of serious problems, including reduced blood cell counts and liver problems.

Diet & Lifestyle Advise

  • Stay hydrated: Drink enough fluids unless your doctor has advised you to restrict fluids.
  • Manage nausea: If you feel sick, smaller meals and taking multiple capsules gradually over about 15 minutes may help.
  • Reduce infection exposure: Wash your hands regularly and avoid close contact with people who are unwell, particularly if your blood tests show a low white blood cell count.
  • Attend blood tests: Regular monitoring helps your doctor detect changes in blood cells, liver function, kidney function, and medicine levels early.
     
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How Soon It Starts Working

The time required for Flucyto Tablet to start to work: The time required for Flucyto Tablet to show its action is unknown. The time for which the effects of Flucyto Tablet last: The duration of action for Flucyto Tablet is unknown.

What if you forget to take Flucyto Tablet

If you miss a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses together to make up for the missed dose.

Storage

• Store Flucyto Tablet according to the temperature and storage instructions provided with your product label, typically between 20°C and 25°C.

Drug Warnings

  • Regular monitoring: Flucytosine has a narrow therapeutic index, meaning there is a relatively small difference between an effective amount and an amount that may cause serious side effects. Keep all appointments for blood tests and medicine-level monitoring.
  • Kidney monitoring: Tell your doctor if you have kidney problems. Poor kidney function can cause flucytosine to build up in your blood and increase the risk of side effects.
  • Blood cell monitoring: Flucyto Tablet can reduce white blood cells, red blood cells, and platelets. Consult your doctor right away if you develop fever, unusual weakness, frequent infections, unusual bruising, or bleeding.
  • Liver monitoring: Your doctor may check your liver function during treatment. Report yellowing of your skin or eyes, dark urine, or severe abdominal pain.
  • Combination treatment: Flucyto Tablet is often used with another antifungal medicine for serious infections. Take all prescribed antifungal medicines exactly as directed.
  • Do not stop early: Continue treatment for the prescribed duration even if your symptoms improve, unless your doctor tells you to stop.
     

Drug-Drug Interactions

verifiedApollotooltip

  • Medicines that can affect the kidneys (e.g. aminoglycoside antibiotics, amphotericin B): These medicines may affect kidney function, which can cause flucytosine levels to rise and increase the risk of serious side effects. Close monitoring may be needed.

  • Medicines that reduce blood cell production (e.g. certain chemotherapy medicines): Using these with Flucyto Tablet may further reduce blood cell counts and increase the risk of infection, anaemia, or bleeding.
  • Cytarabine: This chemotherapy medicine may reduce the antifungal activity of flucytosine by interfering with its uptake into fungal cells.
     
FlucytosineLevacetylmethadol
Critical
FlucytosineClozapine
Severe

Drug-Drug Interactions

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FlucytosineLevacetylmethadol
Critical
How does the drug interact with Flucyto Tablet:
Coadministration of Flecainide with Levacetylmethadol can increase the risk of irregular heart rhythms.

How to manage the interaction:
Although there is an interaction between Flucyto Tablet and Levacetylmethadol, it can be taken if it is recommended by a doctor. However, consult a doctor if you experience fever, shortness of breath, or chest discomfort. Do not discontinue any medications without consulting a doctor.
FlucytosineClozapine
Severe
How does the drug interact with Flucyto Tablet:
Co-administration of Flucyto Tablet with Clozapine can increase the risk of developing infections.

How to manage the interaction:
There may be a possibility of interaction between Flucyto Tablet and Clozapine, but it can be taken if prescribed by a doctor. If you experience any symptoms like fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
FlucytosineDeferiprone
Severe
How does the drug interact with Flucyto Tablet:
Coadministration of Flucyto Tablet with Deferiprone can increase the risk of developing infections.

How to manage the interaction:
Although there is a possible interaction between Flucyto Tablet and Deferiprone, you can take these medicines together if prescribed by your doctor. If you experience fever, sore throat, body pain, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
FlucytosineCladribine
Severe
How does the drug interact with Flucyto Tablet:
Taking Cladribine with Flucyto Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Flucyto Tablet and Cladribine together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, diarrhea, soreness, muscle aches, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
FlucytosineMethotrexate
Severe
How does the drug interact with Flucyto Tablet:
Combine use of entecavir with methotrexate may increase the effectiveness of everolimus.

How to manage the interaction:
Although there is a possible interaction between everolimus and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without first consulting to your doctor.
FlucytosineIndometacin
Severe
How does the drug interact with Flucyto Tablet:
Coadministration of Flucyto Tablet with Indomethacin can increase the risk of developing infections.

How to manage the interaction:
Although there is a possible interaction between Flucyto Tablet and Indometacin, you can take these medicines together if prescribed by your doctor. Contact a doctor if you experience fever, muscle ache, sore throat, or shortness of breath. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Food: No specific food interaction is known to require routine food avoidance with Flucyto Tablet . It can generally be taken with or without food. Follow your doctor's instructions about how to take each dose.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Flucyto Tablet is used to treat Fungal infections.
Flucyto Tablet works by interfering with the synthesis of fungal protein and DNA. Thereby, it helps treat fungal infections.
Flucyto Tablet should be used with extreme caution in patients with bone marrow depression. Frequent monitoring of liver function and hematopoietic system is advised.
Flucytosine has a narrow therapeutic index, meaning the effective and potentially harmful levels are relatively close. Blood tests help your doctor check medicine levels, blood cell counts, kidney function, and liver function so your treatment can be adjusted safely.
Yes. Flucyto Tablet can generally be taken with or without food. If you need several capsules for one dose, taking them one at a time over about 15 minutes may help reduce nausea.
Flucytosine is often combined with another antifungal, particularly for serious cryptococcal infections. Combination treatment improves antifungal activity and helps reduce the chance that the fungus will become resistant to flucytosine.
Consult your doctor right away. These symptoms may indicate reduced blood cell counts, which can occur during flucytosine treatment.
Flucytosine may pose risks during pregnancy. Tell your doctor if you are pregnant or planning a pregnancy so they can assess whether the expected benefit of treatment outweighs the potential risk.
Yes. Flucytosine is mainly removed through the kidneys. If your kidneys are not working normally, the medicine can build up in your blood, so your doctor may change your dose or how often you take it.
Flucyto Tablet is generally reserved for certain serious fungal infections and is not normally used for common superficial infections such as athlete's foot. Your doctor will choose an antifungal based on the type and location of the infection.

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Country of origin

India

Manufacturer/Marketer address

S-40, 2Nd Floor, Janta Market, Rajouri Garden, New Delhi - 110 027. India
Other Info - FLU0775
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