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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Formin Plus 500 Tablet is used in the treatment of Type 2 diabetes mellitus. It contains Metformin and Methylcobalamin, which decrease liver glucose production and intestinal glucose uptake, and also helps treat vitamin B12 deficiency. It may cause side effects such as changes in taste, nausea, vomiting, diarrhoea, headache, loss of appetite, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Formin Plus 500 Tablet

Formin Plus 500 Tablet used in the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than usual. It occurs when the body does not produce enough insulin (metabolises glucose), or if it is produced, it cannot function properly in the body.

Formin Plus 500 Tablet is a combination of two medicines: Metformin and Methylcobalamin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. It may deplete vitamin B12 levels. Therefore, it is administered with methylcobalamin, which can help treat vitamin B12 deficiency. Thus, Formin Plus 500 Tablet does not cause a sudden drop in blood glucose levels or significant hypoglycemia.

You should take this medicine as prescribed by your doctor. You may experience side effects such as changes in taste, nausea (feeling sick), vomiting (falling sick), diarrhoea, headache, anorexia (loss of appetite), and sweating. Inform your doctor if any of these side effects persist or worsen.

Do not take Formin Plus 500 Tablet if you are allergic to any of its contents. Before taking Formin Plus 500 Tablet , inform your doctor if you have liver problems, severe kidney failure, uncontrolled diabetes, dehydration due to severe diarrhoea or vomiting, severe infections, acute heart failure or heart attack, and alcoholism. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Formin Plus 500 Tablet

Formin Plus 500 Tablet is used in the treatment of Type 2 Diabetes Mellitus. The detailed uses of Formin Plus 500 Tablet are as follows:
• Management of Diabetes: Formin Plus 500 Tablet is commonly prescribed to help regulate blood sugar levels in patients with type 2 diabetes, particularly those who may require additional medication alongside lifestyle changes.
• Improvement of Glycemic Control: Formin Plus 500 Tablet aids in improving overall glycemic control by enhancing insulin sensitivity and decreasing hepatic glucose production.
• Weight Management: In some cases, Formin Plus 500 Tablet can assist in weight management for diabetic patients, as it may help reduce appetite or modify fat metabolism.
• Prevention of Diabetes Complications: Regular use of Formin Plus 500 Tablet can contribute to the prevention of long-term complications associated with diabetes, such as neuropathy, nephropathy, and retinopathy.

Directions for Use

• Take Formin Plus 500 Tablet with food to avoid stomach upset or as advised by a doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure its safety. • Swallow the medicine as a whole with a glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

Formin Plus 500 Tablet is a combination of two medicines: Metformin and Methylcobalamin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Methylcobalamin reduces vitamin B12 deficiency. Formin Plus 500 Tablet does not cause significant hypoglycemia (sudden lowering of the blood glucose level). It is usually preferred in obese patients with diabetes as it may cause weight loss and lower the complications of diabetes.

How Formin Plus 500 Tablet Works

Formin Plus 500 Tablet is a combination of two medicines: Metformin and Methylcobalamin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. It may deplete vitamin B12 levels. Therefore, it is administered with methylcobalamin, which can help treat vitamin B12 deficiency. Thus, Formin Plus 500 Tablet does not cause a sudden drop in blood glucose levels or significant hypoglycemia.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Formin Plus 500 Tablet

Do not take more than the prescribed dose of Formin Plus 500 Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Formin Plus 500 Tablet may cause a rare and serious side effect, ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems, as their normal functioning is required to eliminate excess lactic acid from the body.  Do not consume excess alcohol, as it increases the risk of lactic acidosis. It should be used with caution in patients with heart disease as it increases the risk of heart failure. If you have dehydration (severe loss of body fluids) due to severe vomiting, diarrhoea, exposure to heat, or fever, stop taking Formin Plus 500 Tablet and immediately seek medical attention. Formin Plus 500 Tablet may cause electrolyte imbalance, so taking this medicine during dehydration can worsen the condition.

Drug-Drug Interactions

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MetforminMetrizamide
Critical
MetforminIopanoic acid
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Formin Plus 500 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Formin Plus 500 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIopanoic acid
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Iopanoic acid with Formin Plus 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Formin Plus 500 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Iodixanol with Formin Plus 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Formin Plus 500 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Ioversol with Formin Plus 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Formin Plus 500 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Iopentol with Formin Plus 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Formin Plus 500 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIobenzamic acid
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Formin Plus 500 Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Formin Plus 500 Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Formin Plus 500 Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Formin Plus 500 Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Iotroxic acid with Formin Plus 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Formin Plus 500 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Ioglycamic acid with Formin Plus 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Formin Plus 500 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Formin Plus 500 Tablet:
Co-administration of Iohexol with Formin Plus 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Formin Plus 500 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grains.
  • Eat at regular intervals. Do not take a long gap between meals or snacks.
  • Monitor your blood sugar level regularly, especially when there are significant fluctuations.
  • Invest in at least 150 minutes of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates with whole-grain foods and increase your intake of fruits, vegetables, and other fibre-enriched foods.
  • Reduce your intake of saturated fats (or hidden fats) in foods like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. You may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil for frying.
  • Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques, such as mindfulness, yoga, or meditation, to help control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, and cheese, etc.).
  • Maintain your blood pressure as close to normal (120/80) as possible, as it reduces the risk of cardiovascular diseases in patients with diabetes.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Unsafe

Alcohol may increase the risk of side effects and worsen the condition.

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Pregnancy

Consult your doctor

Formin Plus 500 Tablet is a category B drug. It should be used in pregnant women only if clinically needed.

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Breast Feeding

Unsafe

Formin Plus 500 Tablet should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.

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Driving

Safe if prescribed

Formin Plus 500 Tablet does not affect your ability to drive.

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Liver

Caution

Formin Plus 500 Tablet should be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Formin Plus 500 Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Consult your doctor

Formin Plus 500 Tablet can be used in children above 10 years of age if clinically required.

Have a query?

FAQs

Formin Plus 500 Tablet is used in the treatment of Type 2 diabetes mellitus.

Formin Plus 500 Tablet is a combination of Metformin and Methylcobalamin. Metformin reduces blood glucose levels by decreasing liver glucose production and intestinal glucose uptake. Methylcobalamin helps reduce vitamin B12 deficiency, which can occur due to the use of metformin.

Inform your doctor before having an X-ray or CT scan that you are taking Formin Plus 500 Tablet . Some imaging scans may involve the injection of contrast materials that contain iodine into your bloodstream, which may affect your kidney function.

Formin Plus 500 Tablet is recommended for the treatment of type 2 diabetes and not used for treating type 1 diabetes, a condition which occurs mainly due to deficiency of insulin.

Formin Plus 500 Tablet is recommended for treating type 2 diabetes in obese patients as this medicine may affect weight loss. However, if you experience excessive weight loss, consult your doctor immediately.

Formin Plus 500 Tablet may not cause significant hypoglycemia (a reduction in blood sugar levels). However, its action is to reduce blood glucose levels in diabetes patients and can cause hypoglycemia if taken together with other medicines to treat diabetes, so consult a doctor if you have severe or recurrent hypoglycemic episodes while using Formin Plus 500 Tablet .

The best diabetes medicine depends on various factors, including the type of diabetes (type 1 or 2), age, medical history, and other health conditions. What works for one person may not work for another. Consulting a healthcare professional is essential to determine the most effective treatment plan, as they will consider individual factors and develop a personalised approach tailored to your specific needs.

Do not take Formin Plus 500 Tablet if you have severe kidney damage, kidney failure, or are on dialysis. Additionally, individuals with metabolic acidosis, including diabetic ketoacidosis, should not take Formin Plus 500 Tablet . Pregnant or breastfeeding women should consult their doctor before taking Formin Plus 500 Tablet . It's essential to discuss your medical history and any underlying conditions with your doctor before starting Formin Plus 500 Tablet .

If you are pregnant or planning to become pregnant, consult your doctor before taking Formin Plus 500 Tablet . Your doctor will weigh the potential benefits and risks to determine whether it is safe for you to use during pregnancy.

The common side effects of Formin Plus 500 Tablet are changes in taste, nausea, vomiting, diarrhoea, headache, anorexia (loss of appetite), and sweating. Please consult your doctor if any of these side effects persist or worsen.

Avoid excessive consumption of alcohol along with Formin Plus 500 Tablet , as it may increase the risk of lactic acidosis.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - FOR0309

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