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compositionComposition:FOSAPREPITANT-150MG
prescriptionPrescription Medicine
Fossamart Injection

Fossamart Injection is used to treat Chemotherapy-induced nausea and vomiting. It contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

FOSAPREPITANT-150MG

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Fossamart Injection

Fossamart Injection belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines). Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Fossamart Injection contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Fossamart Injection will be administered by a healthcare professional; do not self-administer. In some cases, Fossamart Injection may cause common side effects such as headache, hiccups, tiredness, loss of appetite, indigestion, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately. 

If you are allergic to Fosaprepitant or other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Fossamart Injection. Drive only if you are alert after receiving Fossamart Injection. If you are taking other prescription or non-prescription medicines, inform your doctor before receiving Fossamart Injection.

Uses of Fossamart Injection

Fossamart Injection is used in the treatment of Chemotherapy-induced nausea and vomiting. The detailed uses of Fossamart Injection are as follows:

  • Prevention of acute and delayed nausea and vomiting: Fossamart Injection is used to prevent nausea and vomiting associated with chemotherapy.

Key Benefits

Fossamart Injection contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Side effects of Fossamart Injection
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • The doctor or healthcare professional will administer Fossamart Injection.
  • Do not self-administer.

How Fossamart Injection Works

Fossamart Injection contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting.
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Alcohol

Consult your doctor

The interaction of alcohol with Fossamart Injection is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Fossamart Injection. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Fosaprepitant is excreted in breast milk. Hence, if you are a nursing mother, discuss with your doctor about the best way to feed your baby if you receive Fossamart Injection.

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Driving

Caution

Fossamart Injection may cause dizziness or sleepiness in some people. Therefore, if you feel dizzy or sleepy after receiving Fossamart Injection, avoid driving or operating machinery.

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Liver

Caution

If you have liver disease, inform your doctor before receiving Fossamart Injection.

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Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before receiving Fossamart Injection.

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Children

Caution

If you have any concerns regarding the use of Fossamart Injection in children, please consult a doctor.

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Heart

Caution

Fossamart Injection should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Fossamart Injection.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Fossamart Injection to geriatric patients. Your doctor will prescribe Fossamart Injection if the benefits outweigh the risks.

What if I have taken an overdose of Fossamart Injection

As Fossamart Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, skinless poultry, lean meats, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Have a query?

How Soon It Starts Working

The time required for Fossamart Injection to start to work: Fossamart Injection ideally shows its action within 30 minutes after administration. The time for which the effects of Fossamart Injection last: The duration of action for Fossamart Injection is unknown.

What if you forget to take Fossamart Injection

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep Fossamart Injection out of the sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.

Drug Warnings

If you are allergic to Fosaprepitant or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Fossamart Injection. Drive only if you are alert after receiving Fossamart Injection. If you are taking any other prescription or non-prescription medicines, inform your doctor before receiving Fossamart Injection. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Fossamart Injection to check your blood clotting.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Avoid using Fossamart Injection with antipsychotics (pimozide), anti-allergic drugs (astemizole, terfenadine), and gastroprokinetic agents (cisapride). Fossamart Injection may interact with immunosuppressants (tacrolimus, everolimus, cyclosporine, sirolimus), pain killers (fentanyl, alfentanil), a medicine used to treat an irregular heartbeat (quinidine), anticancer medicines (etoposide, vinorelbine, irinotecan, ifosfamide), blood thinners (acenocoumarol, warfarin), antibiotics (clarithromycin, telithromycin, rifampicin), anticonvulsants (phenytoin, carbamazepine), medicines used to produce calmness or help you sleep (triazolam, phenobarbital, midazolam), antifungals (ketoconazole, voriconazole, posaconazole, itraconazole), antidepressants (nefazodone), a medicine used to treat high blood pressure (diltiazem), corticosteroids (dexamethasone), anti-anxiety medicines (alprazolam), antidiabetic agent (tolbutamide) and medicines used to treat migraines and HIV infections.

Drug-Food Interactions: Fossamart Injection may interact with St. John’s Wort (herbal preparation used to treat depression).

Drug-Disease Interactions: If you have any liver problems, inform your doctor before receiving Fossamart Injection.

FosaprepitantCisapride
Critical
FosaprepitantLomitapide
Critical

Drug-Drug Interactions

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FosaprepitantCisapride
Critical
How does the drug interact with Fossamart Injection:
Coadministration of Fossamart Injection with Cisapride can increase the levels of Cisapride in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fossamart Injection with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantLomitapide
Critical
How does the drug interact with Fossamart Injection:
When Fossamart Injection is taken with Lomitapide, it can increase the levels of Lomitapide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Fossamart Injection with Lomitapide together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - diarrhea, nausea, vomiting, pain, discomfort, indigestion, constipation, liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, dark colored urine, bleeding or vomiting - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
FosaprepitantEliglustat
Critical
How does the drug interact with Fossamart Injection:
When Fossamart Injection is taken with Eliglustat, can increase Eliglustat levels in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Fossamart Injection and Eliglustat, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantTerfenadine
Critical
How does the drug interact with Fossamart Injection:
When Fossamart Injection is taken with Terfenadine, it can lower the rate at which Fossamart Injection is broken down and increases its levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fossamart Injection and Terfenadine together is generally avoided as it can show an interaction, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like Chest discomfort, Shortness of breath, Weakness, or palpitations, it's important to call your doctor right away - they can be serious heart problems. Do not discontinue any medications without consulting a doctor.
FosaprepitantAstemizole
Critical
How does the drug interact with Fossamart Injection:
Coadministration of Fossamart Injection with Astemizole can increase the levels of Astemizole in the body. This increases the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fossamart Injection with Astemizole together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantFlibanserin
Critical
How does the drug interact with Fossamart Injection:
Coadministration of Fossamart Injection with Flibanserin can increase the levels of Flibanserin in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fossamart Injection with Flibanserin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FosaprepitantPimozide
Critical
How does the drug interact with Fossamart Injection:
When Pimozide is taken with Fossamart Injection, it can increase the Pimozide levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fossamart Injection with Pimozide is not recommended, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantRanolazine
Severe
How does the drug interact with Fossamart Injection:
When Fossamart Injection is taken with Ranolazine, can increase the levels of Ranolazine in the body. This can increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fosamprepitant with Ranolazine can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.
FosaprepitantDeflazacort
Severe
How does the drug interact with Fossamart Injection:
Coadministration of Fossamart Injection with Deflazacort can increase the levels of Deflazacort in the body.

How to manage the interaction:
Taking Fossamart Injection with Deflazacort together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantCobimetinib
Severe
How does the drug interact with Fossamart Injection:
Coadministration of Fossamart Injection with Cobimetinib can increase the levels of Cobimetinib in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fossamart Injection with Cobimetinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, diarrhea, mouth sores, bleeding, heart problems, rash, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Fossamart Injection is used to treat Chemotherapy-induced nausea and vomiting.

Fossamart Injection works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Fossamart Injection may cause constipation as a common side effect. However, if the condition persists or worsens, please consult your doctor.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain intrauterine devices (IUDs) as they may not work properly when taken together with Fossamart Injection. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Fossamart Injection and for up to 1 month after using Fossamart Injection.

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Author Details

Veda MaddalaDoctor badge

Written By

  • Veda Maddala

    M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

  • Santoshini Reddy G

    M Pharmacy

Last Updated

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Country of origin

India
Other Info - FO32965
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