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compositionComposition:FUROSEMIDE-100MG
prescription
Prescription Medicine
info
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Frusenex-100 Tablet is used to treat high blood pressure, heart failure, and oedema (a build-up of fluid in the body). It contains Furosemide, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. In some cases, you may experience side effects such as dehydration, headache, nausea, or dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FUROSEMIDE-100MG

Manufacturer/Marketer :

Geno Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Frusenex-100 Tablet

This medicine is a prescription treatment used to reduce extra fluid in the body, a condition known as oedema. It is commonly prescribed for people with heart failure, liver disease, or kidney disease, and is also used to manage high blood pressure.

For the best results, you should take this medicine consistently every day exactly as prescribed. It can be taken with or without food, though taking it with food may help prevent an upset stomach. Combining this treatment with a low-salt diet can significantly improve your results.

While taking this medicine, you may experience mild side effects like increased urination or mild dizziness. If you experience severe muscle weakness, extreme thirst, or ringing in your ears, you should contact your doctor immediately.

Do not take this if you are unable to urinate. If you have a history of allergy to sulfonamide-containing medicines, tell your doctor before starting Frusenex-100 Tablet . Cross-reactivity between Frusenex-100 Tablet and sulfonamide antibiotics is not well established, and your doctor will assess whether this medicine is appropriate for you. Talk to your doctor before starting this medicine if you have kidney problems, liver damage, gout, or diabetes.

This medicine can interact with certain other blood pressure drugs, pain relievers, and alcohol, which may cause your blood pressure to drop too low. If you are pregnant, breastfeeding, or an older adult, consult your healthcare provider to discuss safety and monitoring.

Uses of Frusenex-100 Tablet

Frusenex-100 Tablet contains furosemide and is used to remove excess fluid from the body and help manage certain cardiovascular conditions. The detailed uses of Frusenex-100 Tablet are as follows: 

  • Fluid retention (oedema): Frusenex-100 Tablet helps clear excess water from your body caused by heart failure, liver disease, or kidney disorders, reducing swelling in your legs, ankles, and abdomen.
  • High blood pressure (hypertension): It helps lower high blood pressure, which reduces your risk of experiencing serious cardiovascular events like strokes or heart attacks.

Key Benefits

Frusenex-100 Tablet helps remove excess fluid from the body, providing relief from symptoms caused by fluid retention while reducing the strain on the heart and other organs. This can improve comfort and support better day-to-day functioning.

  • Relief from Swelling and Fluid Retention: By helping the body eliminate excess fluid, Frusenex-100 Tablet reduces swelling in the legs and feet, making movement more comfortable and improving daily mobility.
  • Improved Breathing and Comfort: Removing excess fluid from the lungs helps relieve shortness of breath, making it easier to breathe comfortably and sleep through the night.
  • Protection Against Long-Term Organ Strain: By helping keep blood pressure within a healthy range, Frusenex-100 Tablet reduces strain on the heart and kidneys, supporting their long-term health and function.
Side effects of Frusenex-100 Tablet
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Let your doctor know if you experience symptoms such as fatigue, weakness, muscle cramps, or respiratory depression. Hyperchloremia may cause these.
  • Hyperchloremia is a condition in which the blood has an excessive level of chloride ions, which can disrupt the body's acid-base balance and lead to various complications.
  • Your doctor will thoroughly evaluate to determine if your medication is causing the hyperchloremia.
  • If your medication is found to be the cause, your doctor may adjust your medication regimen or switch you to alternative medicines.
  • To manage hyperchloremia, focus on consuming a balanced diet that is low in chloride-rich foods. Include potassium-rich foods like bananas, leafy greens, and sweet potatoes to help balance electrolyte levels.
  • Adopting a healthy lifestyle can help manage your condition. Aim for regular physical activity, stress-reducing techniques, and adequate sleep to help your body recover.
  • Regular monitoring and follow-ups with your doctor are crucial to managing your condition. Schedule check-ups as recommended by your doctor to monitor your symptoms and adjust your treatment plan as needed.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

Directions for Use

To get the maximum benefit from furosemide treatment with Frusenex-100 Tablet , follow these step-by-step instructions carefully:

  • Take this medicine by mouth exactly as prescribed by your doctor.
  • Swallow the tablet whole with a full glass of water.
  • Because this medicine increases urination, it is best to take it early in the day.
  • You may take this medicine with or without food.

Always follow your doctor's exact instructions regarding your dosage and treatment duration. Do not stop taking Frusenex-100 Tablet without consulting your healthcare provider.

How Frusenex-100 Tablet Works

Frusenex-100 Tablet contains furosemide, which works by acting directly on your kidneys, specifically in an area called the loop of Henle. It blocks your body from reabsorbing salt and water, prompting your kidneys to filter them out of your bloodstream. By releasing these excess salts and fluids through your urine, the medicine reduces the overall volume of fluid circulating in your blood vessels. This process lowers the pressure on your blood vessel walls and relieves the swelling in your body tissues.
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Alcohol

Caution

You are recommended not to consume alcohol along with Frusenex-100 Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Frusenex-100 Tablet should not be used during pregnancy unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

Frusenex-100 Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Unsafe

It is not recommended to drive after taking Frusenex-100 Tablet as it may occasionally cause drowsiness.

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Liver

Caution

Frusenex-100 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Frusenex-100 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Caution

Frusenex-100 Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

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Heart

Safe if prescribed

Frusenex-100 Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Frusenex-100 Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Frusenex-100 Tablet

Do not take more than the prescribed dose of Frusenex-100 Tablet as it may cause overdose. The symptoms of overdose include headaches, dizziness, fainting, pounding or irregular heartbeat, extreme thirst and excessive urination. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Monitor your salt intake: Limit high-sodium foods like canned soups, processed meats, and salty snacks, as salt causes your body to hold onto water and works against your medicine.
  • Eat potassium-rich foods: This medicine can cause your body to lose potassium. Unless your doctor tells you otherwise, include foods like bananas, oranges, spinach, and sweet potatoes in your diet.
  • Track your daily weight: Weigh yourself every morning at the same time, after using the bathroom but before eating. Let your doctor know if you gain more than 2 to 3 pounds in a single day, as this can be a sign of fluid buildup.
  • Stand up slowly: To prevent dizziness or fainting when getting out of bed or a chair, stand up gradually to let your blood pressure adjust.
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How Soon It Starts Working

The time required for Frusenex-100 Tablet to start to work: The time required for Frusenex-100 Tablet to start to work is 30 to 60 minutes after administration. The time for which the effects of Frusenex-100 Tablet last: The effect of Frusenex-100 Tablet lasts for 6 to 8 hours.

What if you forget to take Frusenex-100 Tablet

If you forget to take a dose of Frusenex-100 Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dose. Do not take a double dose to make up for the missed one.

Storage

•Store this medicine at room temperature, between 68°F and 77°F (20°C to 25°C) •Keep the tablets in their original container, tightly closed, to protect them from light and moisture.

Drug Warnings

  • Monitor Blood Pressure and Kidney Function: Check your blood pressure and attend regular kidney function tests as recommended by your doctor to ensure the medicine is working safely and effectively.
  • Follow Fluid Intake Instructions: Be mindful of how much fluid you drink, as your doctor may advise you to limit your fluid intake while taking this medication.
  • Protect Your Skin from Sunlight: Avoid excessive sun exposure and use protective clothing or sunscreen, as this medicine may increase your sensitivity to sunlight and the risk of sunburn.
  • Monitor Blood Sugar Levels: If you have diabetes, check your blood sugar levels regularly, as this medication may sometimes cause blood sugar levels to rise.
     

Drug-Drug Interactions

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Drug-Drug Interactions


Inform your doctor if you are taking any of the following medicines, as they may interact with Frusenex-100 Tablet : 

  • Blood pressure medicines: Combining this medicine with other blood pressure drugs can cause your blood pressure to drop too low, leading to dizziness.
  • NSAIDs (pain relievers like ibuprofen): These medicines can reduce the effectiveness of your treatment and increase the risk of kidney damage.
  • Digoxin: Low potassium levels caused by this medicine can increase the risk of serious side effects from digoxin.
  • Lithium: Taking these two together can decrease kidney clearance of lithium, leading to dangerously high levels of lithium in your blood.
  • Aminoglycoside antibiotics (such as gentamicin): Taking these medicines with Frusenex-100 Tablet may increase the risk of hearing problems or hearing loss, especially at higher doses or in people with kidney impairment.
  • Cisplatin: Using cisplatin together with Frusenex-100 Tablet may increase the risk of kidney damage and hearing-related side effects.
  • Probenecid: This medicine can reduce the effectiveness of Frusenex-100 Tablet by affecting how it is processed and removed by the kidneys.


Drug-Food Interactions

Certain foods, beverages, and supplements may affect how Frusenex-100 Tablet works or increase the risk of side effects. Examples include: 

  • Liquorice: Consuming natural liquorice can worsen potassium loss, increasing your risk of muscle cramps and heart rhythm issues.


Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Frusenex-100 Tablet , as additional monitoring or treatment adjustments may be required: 

  • Gout: This medicine can increase uric acid levels in your body, which may trigger a painful gout flare-up.
  • Diabetes: It may affect your blood sugar control, requiring you to monitor your glucose levels more closely.
  • Kidney or liver disease: If your kidney or liver function is severely impaired, your doctor will need to monitor you closely to prevent complications.
FurosemideZiprasidone
Critical
FurosemideAmikacin
Severe

Drug-Drug Interactions

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FurosemideZiprasidone
Critical
How does the drug interact with Frusenex-100 Tablet:
Taking Ziprasidone with Frusenex-100 Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Frusenex-100 Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
FurosemideAmikacin
Severe
How does the drug interact with Frusenex-100 Tablet:
Coadministration of Amikacin with Frusenex-100 Tablet can increase the risk of developing kidney disorder and other side effects.

How to manage the interaction:
Although taking amikacin and Frusenex-100 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, muscle cramps, vomiting, or weakness, consult the doctor. Do not discontinue any medications without a doctor's advice.
FurosemideTizanidine
Severe
How does the drug interact with Frusenex-100 Tablet:
Combining Tizanidine and Frusenex-100 Tablet can lower your blood pressure.

How to manage the interaction:
Taking Tizanidine and Frusenex-100 Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, contact your doctor immediately. Avoid driving or operating hazardous machinery until you know how the medications affect you, use caution when getting up from a sitting or lying position, and do not discontinue any medications without consulting your doctor.
FurosemideGlimepiride
Severe
How does the drug interact with Frusenex-100 Tablet:
Co-administration of Frusenex-100 Tablet may interfere with blood glucose control and lower the effectiveness of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Frusenex-100 Tablet if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FurosemideTobramycin
Severe
How does the drug interact with Frusenex-100 Tablet:
Taking Frusenex-100 Tablet with Tobramycin can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although there is a possible interaction between Tobramycin and Frusenex-100 Tablet, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting your doctor.
FurosemideStreptomycin
Severe
How does the drug interact with Frusenex-100 Tablet:
Coadministration of Streptomycin and Frusenex-100 Tablet may increase the risk or severity of hearing or kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Streptomycin and Frusenex-100 Tablet, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, hearing difficulty, swelling, body aches, increased or decreased urination, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
FurosemideDiclofenac
Severe
How does the drug interact with Frusenex-100 Tablet:
Concomitant administration of diclofenac and Frusenex-100 Tablet may decrease the therapeutic efficacy of Frusenex-100 Tablet and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between diclofenac and Frusenex-100 Tablet, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Frusenex-100 Tablet is used to treat high blood pressure and oedema (a fluid build-up in the body).
Frusenex-100 Tablet belongs to a class of medicines called diuretics (water pills). It increases urine production, helping the body remove excess fluid and salt. This reduces fluid build-up (oedema) and decreases the amount of fluid circulating in the blood vessels, which helps lower blood pressure.
Yes, Frusenex-100 Tablet is contraindicated in people with known allergy to any of the components of Frusenex-100 Tablet . It should be avoided in people with severe kidney or liver impairment and in people with anuria (reduction or absence of urine).
No, you should not stop taking Frusenex-100 Tablet without consulting your doctor, even if you feel better or your blood pressure is under control. High blood pressure is often a long-term condition that requires ongoing treatment. Your doctor may ask you to monitor your blood pressure for a period of time and may adjust the dose if needed, but sudden discontinuation is not recommended. Continue taking Frusenex-100 Tablet for as long as prescribed by your doctor.
No, the occurrence of gout due to Frusenex-100 Tablet is very rare. However, it can cause an increase in the levels of uric acid.
Both Frusenex-100 Tablet and Torasemide are loop diuretics used to manage high blood pressure and edema caused by underlying kidney, liver, or lung conditions. Frusenex-100 Tablet is also used to treat hypercalcemia (high calcium levels in the blood), which Torasemide does not. Torasemide has a longer-lasting effect and is generally considered safer for patients with kidney failure compared to Frusenex-100 Tablet .
Yes, it’s important to drink lot of water and stay hydrated while taking Frusenex-100 Tablet , as it increases urine production to remove excess fluids. This may raise the risk of dehydration during exercise, or if you sweat a lot. However, if you have heart or kidney problems, consult your doctor for advice on the right amount of water to drink.
No, Frusenex-100 Tablet doesn’t cause weight gain. It may lead to weight loss as it helps your body eliminate excess fluids. However, please consult the doctor if there is excessive weight loss or fluid loss.
If you take too much of Frusenex-100 Tablet , you may notice many unwanted side effects such as dizziness, irregular heartbeat, fatigue, headache, frequent urination, dehydration, and temporary loss of consciousness. You may also observe increased thirst and frequent urination. However, please consult the doctor, if you experience any of these effects while taking Frusenex-100 Tablet .
While taking Frusenex-100 Tablet , your weight should be under control with a BMI of 19.5-24.9. Exercise regularly for 150 minutes a week to help reduce blood pressure. Eat a balanced diet with whole grains, fruits, veggies, and low-fat dairy while limiting sodium to 1500-2300 mg daily. Limit the use of alcohol and quit smoking to reduce heart disease risk. Manage your stress levels and spend time peacefully. Include omega-3 fatty acids and use low-fat cooking oils such as olive or canola oil in your diet.
It is usually best to take Frusenex-100 Tablet in the morning or early afternoon. Taking it later in the day, especially after 6:00 PM, can cause you to wake up during the night to urinate, which can disrupt your sleep. Talk to your doctor to determine the best schedule for you.
It is highly recommended to avoid or limit alcohol while taking Frusenex-100 Tablet . Alcohol can increase the risk of side effects like dizziness, lightheadedness, and fainting by causing your blood pressure to drop too low. Talk to your doctor for personalised advice.
Yes, Frusenex-100 Tablet can cause your body to lose potassium, which is an important mineral. Your doctor may monitor your blood potassium levels regularly and might recommend eating potassium-rich foods or taking a potassium supplement. Talk to your doctor before making any major dietary changes.
You should only take Frusenex-100 Tablet during pregnancy if your doctor determines that the benefits outweigh the potential risks. This medicine can also pass into breast milk and may reduce your milk supply. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
When taken by mouth, Frusenex-100 Tablet typically begins working within 30 minutes to 1 hour, and its peak effect usually occurs within 1 to 2 hours. You will likely notice an increase in urination during this time. Talk to your doctor if you do not notice any change in your symptoms.
While Frusenex-100 Tablet is used to treat fluid retention related to kidney issues, taking it in high doses or while severely dehydrated can stress the kidneys. Your doctor will perform regular blood tests to monitor your kidney function while you are on this medicine. Talk to your doctor if you notice decreased urination.
Muscle cramps can be a sign of low potassium or dehydration caused by the medicine. If you experience persistent or severe muscle cramps, contact your healthcare provider. Talk to your doctor or pharmacist about safe ways to manage electrolyte levels.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.4576 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.5867 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Furosemide - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Furosemide Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 19 Feb. 2020]Check here
  6. Furosemide [Drug Label]. 2019. [Accessed on 25 Jul. 2024]Check here
  7. Lasilactone 20 mg/50 mg Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 27 July 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Geno Pharmaceuticals Pvt. Ltd., Pharmaceutical Complex, Tivim Industrial Estate, Karaswada, Mapusa, Goa - 403 526
Other Info - FRU0112
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