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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

G-LOC HP 1 Combikit Tablet is used to treat peptic ulcer disease caused by Helicobacter pylori infection. It kills the bacteria (Helicobacter pylori) causing the infection and reduces the production of stomach acid. It may cause side effects such as headache, diarrhoea, stomach pain, constipation, flatulence, nausea (feeling unwell), vomiting (being sick), skin rash, difficulty sleeping, changes in taste sensation, indigestion, and excessive sweating.

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Whats That

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Synonym :

AMOXICILLIN TRIHYDRATE+CLARITHROMYCIN+ESOMEPRAZOLE MAGNESIUM TRIHYDRATE

Manufacturer/Marketer :

ASCENTRA HEALTHCARE PVT LTD

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About G-LOC HP 1 Combikit Tablet

G-LOC HP 1 Combikit Tablet is an Antacid used to treat peptic ulcer disease caused by Helicobacter pylori infection. Helicobacter pylori is a type of bacteria that infects the stomach and leads to excess acid production. This effect leads to the formation of sores or ulcers in the stomach lining, known as peptic ulcer disease. Symptoms include stomach pain or discomfort, loss of appetite, weight loss, difficulty swallowing, bloating, nausea, and vomiting.  

G-LOC HP 1 Combikit Tablet is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that kills the bacteria (Helicobacter pylori) causing the infection. Esomeprazole is a proton pump inhibitor and acts by reducing the production of stomach acid. Amoxicillin is a penicillin antibiotic and bactericidal (kills the bacteria). It works by preventing the formation of the bacterial cell covering (protective cell wall) necessary for their survival. Together, G-LOC HP 1 Combikit Tablet helps to treat peptic ulcer disease effectively.

G-LOC HP 1 Combikit Tablet is available in the form of tablets. Take this medicine exactly as prescribed by your doctor. G-LOC HP 1 Combikit Tablet may cause side effects such as headache, diarrhoea, stomach pain, constipation, flatulence, nausea (feeling sick), vomiting (being sick), skin rash, difficulty sleeping, changes in the sense of taste, indigestion, and excessive sweating. These side effects typically resolve on their own without requiring medical attention. However, if any of these side effects persist or worsen, consult your doctor immediately.

Do not take G-LOC HP 1 Combikit Tablet if you are allergic to Esomeprazole, Clarithromycin, Amoxicillin, other antibiotics (especially penicillin), other proton pump inhibitors (pantoprazole, lansoprazole, or omeprazole, etc.), or any other contents of it. Before taking G-LOC HP 1 Combikit Tablet, inform your doctor if you have arrhythmias (a condition with irregular heartbeat), hypokalemia (low potassium levels in the blood), severe liver failure, severe kidney problems, heart problems, urination problems, glandular fever (fever, sore throat, swollen glands, and extreme tiredness), lymphatic leukaemia (a type of blood cancer), HIV, and undergoing a blood test for chromogranin A levels (for cancers associated with endocrine (hormonal) and nervous system). Also, inform your doctor if you are pregnant or breastfeeding. G-LOC HP 1 Combikit Tablet should be used with caution in children and may require dose adjustments. Older people may not require any dose adjustments while using G-LOC HP 1 Combikit Tablet. Do not take alcohol, as it may worsen the side effects. G-LOC HP 1 Combikit Tablet may cause dizziness in some patients, so do not drive or operate heavy machinery if you feel dizzy.

Uses of G-LOC HP 1 Combikit Tablet

G-LOC HP 1 Combikit Tablet is used in the treatment of hyperacidity, heartburn, stomach ulcer and Zollinger-Ellison syndrome. The detailed uses of G-LOC HP 1 Combikit Tablet are as follows:<br/>• Management of Gastroesophageal Reflux Disease (GERD): G-LOC HP 1 Combikit Tablet effectively reduces symptoms of GERD, such as heartburn and acid regurgitation, by lowering stomach acid production.<br/>• Healing of Erosive Esophagitis: G-LOC HP 1 Combikit Tablet is often prescribed to promote the healing of inflamed oesophageal tissue caused by prolonged exposure to stomach acid.<br/>• Prevention of Peptic Ulcers: G-LOC HP 1 Combikit Tablet helps prevent peptic ulcer formation, particularly in individuals undergoing long-term NSAID treatment.<br/>• Eradication of Helicobacter pylori: G-LOC HP 1 Combikit Tablet is sometimes included in combination therapy to eliminate Helicobacter pylori infections, which are associated with peptic ulcers.<br/>

Directions for Use

• Take G-LOC HP 1 Combikit Tablet with or without food as advised by a doctor. • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results. • Swallow it as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

G-LOC HP 1 Combikit Tablet is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that kills bacteria (Helicobacter pylori) causing the infection. Esomeprazole is a proton pump inhibitor (responsible for acid production) and acts by reducing stomach acid production. This effect helps to relieve symptoms of peptic ulcer disease. Amoxicillin is a penicillin antibiotic and bactericidal (kills the bacteria). It works by preventing the formation of the bacterial cell covering (protective cell wall) necessary for their survival. Together, G-LOC HP 1 Combikit Tablet is used to treat the infection and peptic ulcer disease.

How G-LOC HP 1 Combikit Tablet Works

G-LOC HP 1 Combikit Tablet is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that kills the bacteria (Helicobacter pylori) causing the infection. Esomeprazole is a proton pump inhibitor and acts by reducing the production of stomach acid. Amoxicillin is a penicillin antibiotic and bactericidal (kills the bacteria). It works by preventing the formation of the bacterial cell covering (protective cell wall) necessary for their survival. Together, G-LOC HP 1 Combikit Tablet helps treat and manage peptic ulcer disease effectively.

Storage

Keep this medicine out of the sight and reach of children.

What if I have taken an overdose of G-LOC HP 1 Combikit Tablet

Do not take more than the prescribed dose of G-LOC HP 1 Combikit Tablet as it may cause an overdose. The symptoms of overdose include stomach pain, vomiting, stomach upset, crystals in the urine (may be seen as cloudy urine) or problems urinating. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

G-LOC HP 1 Combikit Tablet should not be used in patients with arrhythmias or taking antiarrhythmic agents, as it may lead to prolonged QT intervals, which can be life-threatening. While using G-LOC HP 1 Combikit Tablet, if you notice severe or prolonged diarrhoea, vomiting food or blood, black stools, unexplained weight loss, or symptoms of liver disease (jaundice (yellowing of the skin), loss of appetite, dark urine, or itching), stop the medication and consult a doctor immediately. Besides, if you notice skin rashes or lesions, especially on sun-exposed skin, stop the treatment and immediately consult a doctor. G-LOC HP 1 Combikit Tablet increases the risk of Clostridium difficile-associated diarrhoea (inflammation of the large intestine due to Clostridium infection). G-LOC HP 1 Combikit Tablet may increase the risk of fractures, cause liver impairment, and impair the absorption of vitamin B12 in the body when used for prolonged periods.

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical
ClarithromycinDroperidol
Critical

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical
How does the drug interact with G-LOC HP 1 Combikit Tablet:
When Astemizole is taken with G-LOC HP 1 Combikit Tablet, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinDroperidol
Critical
How does the drug interact with G-LOC HP 1 Combikit Tablet:
Co-administration of Droperidol with G-LOC HP 1 Combikit Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinVenetoclax
Critical
How does the drug interact with G-LOC HP 1 Combikit Tablet:
When Venetoclax is taken with G-LOC HP 1 Combikit Tablet, the body's ability to break down Venetoclax may be reduced.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Venetoclax is not recommended, please consult your doctor before taking it.
How does the drug interact with G-LOC HP 1 Combikit Tablet:
Co-administration of Eplerenone and G-LOC HP 1 Combikit Tablet may significantly increase the blood levels and effects of eplerenone.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Eplerenone is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
Critical
How does the drug interact with G-LOC HP 1 Combikit Tablet:
Co-administration of Bepridil with G-LOC HP 1 Combikit Tablet may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinConivaptan
Critical
How does the drug interact with G-LOC HP 1 Combikit Tablet:
When G-LOC HP 1 Combikit Tablet is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinLomitapide
Critical
How does the drug interact with G-LOC HP 1 Combikit Tablet:
When Lomitapide is taken with G-LOC HP 1 Combikit Tablet, it can lower the metabolism of Lomitapide.

How to manage the interaction:
Co-administration of G-LOC HP 1 Combikit Tablet and Lomitapide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and liver damage, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with G-LOC HP 1 Combikit Tablet:
When Cisapride is taken with G-LOC HP 1 Combikit Tablet, the amount of Cisapride in the blood can go up.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Cisapride can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinDihydroergotamine
Critical
How does the drug interact with G-LOC HP 1 Combikit Tablet:
When Dihydroergotamine is taken with G-LOC HP 1 Combikit Tablet, the amount of Dihydroergotamine in the blood can go up.

How to manage the interaction:
Taking G-LOC HP 1 Combikit Tablet with Dihydroergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with G-LOC HP 1 Combikit Tablet:
The combination of Alprazolam and G-LOC HP 1 Combikit Tablet may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and G-LOC HP 1 Combikit Tablet, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; instead, a single raised block is sufficient. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid backflow into the food pipe.
  • Include fibre-rich foods, berries, cherries, leafy green veggies (kale, spinach), and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B 12 that can help cope with the medicine's long-term effects. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics that help prevent excess stomach acid production. Cranberry juice can be beneficial in peptic ulcers and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a 5-minute break every hour by going for a brisk walk or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS
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Alcohol

Caution

Consumption of alcohol may increase the risk of side effects such as nausea, vomiting, and diarrhoea, and worsen the health condition.

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Pregnancy

Caution

G-LOC HP 1 Combikit Tablet is a pregnancy category C medicine and may cause harmful effects to the fetus if used during pregnancy. However, if clinically needed, your doctor may prescribe G-LOC HP 1 Combikit Tablet if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, consult your doctor before using G-LOC HP 1 Combikit Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

G-LOC HP 1 Combikit Tablet may cause dizziness or drowsiness in some patients. So, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

In mild to moderate liver impairment, dose adjustments may not be necessary. However, your doctor may have to adjust the dose in patients with severe liver failure.

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Kidney

Caution

In mild to moderate kidney impairment, dose adjustments may not be necessary. However, in patients with severe kidney failure, your doctor may have to adjust the dose.

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Children

Caution

G-LOC HP 1 Combikit Tablet should be used with caution in children below 12 years. The dose may have to be adjusted by your doctor.

Have a query?

FAQs

G-LOC HP 1 Combikit Tablet is used to treat peptic ulcer disease caused by Helicobacter pylori infection.

G-LOC HP 1 Combikit Tablet is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that works by killing the bacteria (Helicobacter pylori) that is causing the infection. Esomeprazole is a proton pump inhibitor (responsible for acid production) and reduces stomach acid production. Amoxicillin is a penicillin antibiotic with bactericidal (kills the bacteria) action. Together, G-LOC HP 1 Combikit Tablet is used to treat the infection and peptic ulcer disease.

G-LOC HP 1 Combikit Tablet contains Esomeprazole, which is an acid suppressant. It can reduce stomach acid production and relieve symptoms such as acid-related heartburn and indigestion.

G-LOC HP 1 Combikit Tablet may cause side effects such as headache, diarrhoea, stomach pain, constipation, flatulence, nausea (feeling sick), vomiting (being sick), skin rash, difficulty sleeping, changes in the sense of taste, indigestion, and excessive sweating. These side effects typically resolve on their own without requiring medical attention. However, consult your doctor immediately if these side effects persist or worsen.

It is advisable to avoid acidic foods, such as citrus fruits and tomatoes, as well as spicy foods, caffeinated drinks, chocolate, and alcohol. These foods may increase stomach acid production and worsen health conditions.

It is not advised to take G-LOC HP 1 Combikit Tablet for prolonged periods unless prescribed by your doctor. Long-term use of G-LOC HP 1 Combikit Tablet may increase the risk of fractures, impair vitamin B12 absorption, and lead to changes in liver function.

Yes, you can take G-LOC HP 1 Combikit Tablet with other medications if prescribed by the doctor. To prevent any interactions, inform the doctor if you are taking any other medicines, including herbal products or supplements, while on treatment with G-LOC HP 1 Combikit Tablet.

No, G-LOC HP 1 Combikit Tablet is not a steroid. It is a combination medication containing a penicillin-type antibiotic (amoxicillin), a macrolide antibiotic (clarithromycin), and a proton pump inhibitor (esomeprazole). It is used to treat peptic ulcer disease caused by Helicobacter pylori infection.

No, G-LOC HP 1 Combikit Tablet should not be chewed or crushed. It should be taken as a whole, accompanied by a glass of water.

The G-LOC HP 1 Combikit Tablet should be stored in a cool, dry place away from sunlight. Keep it out of sight and reach of children.

Consult the doctor before starting any new medicine while on treatment with G-LOC HP 1 Combikit Tablet. Talk to the doctor if you experience severe diarrhoea, sore throat, white mouth, or vaginal itching/discharge. Drink plenty of fluids while taking G-LOC HP 1 Combikit Tablet. This medicine may cause dizziness; drive only if you are alert. Consult the doctor if you are pregnant or breastfeeding.

Country of origin

India

Manufacturer/Marketer address

15-16, Vinayak Complex, Near Saraswati Complex, Manjalpur, Vadodara Vadodara Gj 390011 In
Other Info - GLO0794

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