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compositionComposition:GABAPENTIN-400MG+NORTRIPTYLINE-10MG
prescription
Prescription Medicine
info
Gabrico-Nt 400/10 Tab 10'S
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GABAPENTIN-400MG+NORTRIPTYLINE-10MG

Manufacturer/Marketer :

Venrico Life Sciences

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Gabrico-Nt 400/10 Tab

Gabrico-Nt 400/10 Tab is a prescription oral medicine used to manage neuropathic pain, which is chronic pain caused by damage to the nerves. It is commonly prescribed to treat persistent nerve discomfort resulting from conditions such as shingles, diabetes, or spinal injuries. By calming overactive nerves, this medicine helps bring relief from burning, shooting, or stabbing sensations.

For this medicine to work effectively, it must be taken daily and consistently at the same times each day. You can take Gabrico-Nt 400/10 Tab with or without food, depending on your preference or your doctor's advice. Combining your medical treatment with simple daily habits, such as gentle stretching and eating balanced meals, can support your body's nerve recovery and overall physical function.

While taking Gabrico-Nt 400/10 Tab , some people may experience mild side effects like dry mouth, drowsiness, or a feeling of lightheadedness. These side effects are often temporary as your body adjusts to the medicine. However, if you experience serious issues like a very fast or irregular heartbeat, severe mood changes, or an allergic reaction, you must consult your doctor immediately.

Before you begin taking Gabrico-Nt 400/10 Tab , tell your doctor if you have a history of heart disease, glaucoma, kidney problems, or depression. Do not take this medicine if you have recently suffered a heart attack or if you are currently taking certain medications for depression called monoamine oxidase inhibitors (MAOIs).

This medicine can interact with alcohol, sleeping aids, and other pain relievers, which can significantly increase drowsiness and cause slow breathing. If you are pregnant, planning to become pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist to discuss whether Gabrico-Nt 400/10 Tab is safe for your specific situation.

Uses of Gabrico-Nt 400/10 Tab

Gabrico-Nt 400/10 Tab is used to manage neuropathic pain. The detailed uses of Gabrico-Nt 400/10 Tab are as follows:

  • Neuropathic pain: Gabrico-Nt 400/10 Tab helps soothe chronic, burning, or shooting nerve pain caused by conditions like diabetic neuropathy or shingles (postherpetic neuralgia).
  • Fibromyalgia: It assists in managing widespread muscle and nerve pain, helping to reduce general physical discomfort.
  • Spinal cord injury discomfort: It helps quiet the hyperactive nerve signals that result from traumatic or inflammatory damage to the spine.

Key Benefits

Gabrico-Nt 400/10 Tab helps manage neuropathic (nerve-related) pain by combining two active ingredients that work through different mechanisms to reduce pain signals. By providing comprehensive pain control, this medicine can help improve comfort, daily functioning, and overall quality of life. It offers several key benefits:

  • Provides Effective Relief from Nerve Pain: By targeting nerve pain through multiple pathways, Gabrico-Nt 400/10 Tab helps reduce symptoms such as burning, tingling, shooting pain, and discomfort associated with nerve damage. This can provide more effective symptom control than a single-agent treatment in appropriate patients.
  • Supports Better Sleep and Daily Well-Being: Persistent nerve pain can interfere with restful sleep and affect mood and energy levels. By helping keep pain under control, particularly during the night, Gabrico-Nt 400/10 Tab may support better sleep quality and improved day-to-day well-being.
  • Helps Improve Mobility and Daily Functioning: Reduced pain can make it easier to perform routine activities, move more comfortably, and participate in rehabilitation or physical therapy programmes when recommended. This can contribute to maintaining independence and supporting long-term recovery.

Directions for Use

Follow these steps to ensure you are taking Gabrico-Nt 400/10 Tab safely and effectively:

  • Swallow the tablet or capsule whole with a full glass of water. Do not crush, chew, or break it, as this can alter how the medicine is absorbed into your system.
  • Take this medicine with or without food. If it causes an upset stomach, taking it with a meal may help.
  • Try to take your dose at the same time every day to keep a steady level of the medicine in your body.
  • Always follow your doctor's exact instructions. Your doctor may start you on a low dose and suggest gradually increasing the dose to find the amount that manages your pain with the fewest side effects.

How Gabrico-Nt 400/10 Tab Works

Gabrico-Nt 400/10 Tab contains two active ingredients that work together in the nervous system to stop pain signals from reaching the brain. Understanding how each component works helps explain why this combination is so effective for nerve pain. The first active ingredient, gabapentin, targets specific calcium channels in the brain and spinal cord. When nerves are damaged, they can become overactive and fire continuous pain signals. This component calms down these hyperactive nerves, reducing the release of pain-transmitting chemicals. The second active ingredient, nortriptyline, is a tricyclic compound that works in the spinal cord. It increases the levels of natural chemical messengers called serotonin and norepinephrine. These chemicals act as natural pain blockers, stopping the pain signals that are traveling up the spinal cord before they can register in the brain.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Gabrico-Nt 400/10 Tab as it may increase dizziness and sleepiness.

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Pregnancy

Consult your doctor

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Gabrico-Nt 400/10 Tab ; your doctor will decide whether Gabrico-Nt 400/10 Tab can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Gabrico-Nt 400/10 Tab may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Gabrico-Nt 400/10 Tab should not be given to children unless prescribed by the doctor.

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Heart

Consult your doctor

Please consult your doctor before using Gabrico-Nt 400/10 Tab if you have pre-existing heart problems. Your doctor will prescribe Gabrico-Nt 400/10 Tab if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Gabrico-Nt 400/10 Tab to geriatric patients. Your doctor will prescribe Gabrico-Nt 400/10 Tab if the benefits outweigh the risks.

What if I have taken an overdose of Gabrico-Nt 400/10 Tab

Do not take more than the prescribed dose of Gabrico-Nt 400/10 Tab as it may cause serious side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Drink plenty of water: Staying well-hydrated and eating high-fibre foods can help prevent constipation, which is a common side effect of this medication.
  • Avoid alcohol: Do not drink alcohol while taking this medicine. Alcohol can dangerously increase drowsiness, dizziness, and the risk of accidents or falls.
  • Manage dry mouth: Chew sugarless gum, suck on ice chips, or sip water frequently to help stimulate saliva production and keep your mouth comfortable.
  • Rise slowly: This medicine can cause dizziness when standing up quickly. Take your time when moving from a sitting or lying position to a standing position.
  • Stay active gently: Engage in low-impact activities like walking or gentle stretching, as approved by your doctor, to help keep your muscles and joints flexible.
     

Have a query?

How Soon It Starts Working

  • The time required for Gabrico-Nt 400/10 Tab to start to work: The time required for Gabrico-Nt 400/10 Tab to show its action is unknown.
  • The time for which the effects of Gabrico-Nt 400/10 Tab last: The duration of action for Gabrico-Nt 400/10 Tab is unknown.

What if you forget to take Gabrico-Nt 400/10 Tab

If you miss a dose of Gabrico-Nt 400/10 Tab , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Store Gabrico-Nt 400/10 Tab at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original packaging, tightly closed, to protect it from moisture and direct sunlight. Avoid storing it in damp places like bathroom cabinets.

Drug Warnings

  • Do not stop taking Gabrico-Nt 400/10 Tab suddenly. Stopping this medicine abruptly can cause withdrawal symptoms such as nausea, headaches, sleep problems, or a sudden, severe return of your nerve pain. Your doctor will help you by gradually decreasing the dose.
  • Avoid driving, riding a bicycle, or operating machinery when you first start taking this medicine, as it can make you feel sleepy or less alert.
  • Monitor your mood closely. If you or your family members notice sudden changes in your behaviour, thoughts of self-harm, or severe anxiety, contact a healthcare professional immediately.
  • Inform your dentist, surgeon, or any other healthcare providers that you are taking Gabrico-Nt 400/10 Tab before undergoing any medical tests or surgical procedures.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Opioids and Sedatives: Taking Gabrico-Nt 400/10 Tab with strong pain relievers, sleeping pills, or muscle relaxants can cause extreme drowsiness and dangerous breathing difficulties.
  • MAO Inhibitors: Do not take this medicine with, or within 14 days of stopping, monoamine oxidase inhibitors (MAOIs), as this can cause a severe and life-threatening rise in blood pressure and body temperature.
  • Heart Medications: Drugs that alter heart rhythm, such as certain antiarrhythmics or antihistamines, can increase the risk of an irregular heartbeat when taken with this medicine.

Drug-Food Interactions

  • Alcohol: Avoid drinking alcohol, as it significantly multiplies the sedative effects of Gabrico-Nt 400/10 Tab , leading to severe drowsiness, confusion, and poor physical coordination.

Drug-Disease Interactions

  • Heart Conditions: This medicine must be used with extreme caution if you have a history of irregular heartbeats, heart disease, or a recent heart attack.
  • Glaucoma: If you have narrow-angle glaucoma, this medicine can increase the pressure inside your eyes, potentially worsening your condition.
  • Kidney Disease: Because your kidneys clear this medicine from your body, having kidney impairment may require your doctor to prescribe a lower dose to prevent the medicine from building up to unsafe levels. 
Gabapentin + NortriptylineBepridil
Critical
Gabapentin + NortriptylineKetamine
Severe

Drug-Drug Interactions

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Gabapentin + NortriptylineBepridil
Critical
How does the drug interact with Gabrico-Nt 400/10 Tab:
Using bepridil together with nortriptyline can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Nortriptyline and Bepridil, but it can be taken if prescribed by a doctor. If you notice irregular heartbeat, feeling suddenly dizzy or lightheaded, fainting, or having a fast or strong heartbeat. Do not stop using any medications without talking to a doctor.
Gabapentin + NortriptylineKetamine
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Using Ketamine together with Gabapentin may increase the risk of serious side effects.

How to manage the interaction:
Although taking Ketamine and Gabapentin together can cause an interaction, it can be taken if a doctor has suggested it. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Gabapentin + NortriptylineDezocine
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Using Gabapentin together with Dezocine can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although Gabrico-Nt 400/10 Tab and Dezocine can cause an interaction, it can be taken if a doctor prescribes it. Consult a doctor if you develop sudden dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not stop using any medications without talking to a doctor.
Gabapentin + NortriptylineEsketamine
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Taking Gabapentin with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Gabapentin and Esketamine together can cause an interaction, it can be taken if a doctor has suggested it. Consult a doctor if you experience any symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not stop using any medications without a doctor's advice.
Gabapentin + NortriptylineAlfentanil
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Using Gabapentin together with Alfentanil can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although Gabrico-Nt 400/10 Tab and Alfentanil can cause an interaction, it can be taken if a doctor prescribes it. Consult a doctor if you develop sudden dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not stop using any medications without talking to a doctor.
Gabapentin + NortriptylineAmiodarone
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Coadministration of Nortriptyline with Amiodarone can increase the severity of irregular heart rhythm.

How to manage the interaction:
Even though Amiodarone and Nortriptyline interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
Gabapentin + NortriptylineBedaquiline
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Coadministration of Nortriptyline with Bedaquiline can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nortriptyline with Bedaquiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Gabapentin + NortriptylineButorphanol
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Co-administration of Butorphanol and Gabapentin may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Butorphanol, you can take these medicines together if prescribed by a doctor. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Gabapentin + NortriptylineMethadone
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Co-administration of Methadone and Gabapentin may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Methadone, you can take these medicines together if prescribed by a doctor. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment please consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Gabapentin + NortriptylineRemifentanil
Severe
How does the drug interact with Gabrico-Nt 400/10 Tab:
Using Gabapentin together with Remifentanil can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Gabapentin with Remifentanil together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Gabrico-Nt 400/10 Tab is indicated for the management of neuropathic pain.

Gabrico-Nt 400/10 Tab contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

To treat your condition effectually, continue taking Gabrico-Nt 400/10 Tab for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Gabrico-Nt 400/10 Tab ; your doctor will reduce the dose gradually.

Gabrico-Nt 400/10 Tab helps in the treatment of diabetic neuropathy (nerve damage in diabetic patients). However, please consult your doctor before starting Gabrico-Nt 400/10 Tab if you have diabetes.

Gabrico-Nt 400/10 Tab should be swallowed as a whole with water; do not crush or chew it.

Gabrico-Nt 400/10 Tab may cause side effects, such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, dry mouth, and tingling sensations. Talk to your doctor if you the side effects persist or worsen.

Gabrico-Nt 400/10 Tab is a combination of two drugs: Gabapentin (anticonvulsant) and Nortriptyline (tricyclic antidepressant).

Eating a balanced meal and exercising regularly may help manage weight gain associated with the use of Gabrico-Nt 400/10 Tab .

Yes, the use of Gabrico-Nt 400/10 Tab may affect your sexual life. Gabrico-Nt 400/10 Tab may cause problems like erectile dysfunction, lower sexual desire and inability to reach orgasm. Consult the doctor if you have any concerns regarding this.

Gabrico-Nt 400/10 Tab may cause serious side effects like hallucination, blurred or double vision, uncontrollably jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat, or mouth ulcers, weakness, unsteadiness when walking, reduced coordination or slowed reactions, and unusual mood or behavioural changes (such as restlessness, nervousness, or excitement). Consult the doctor if you notice these signs.

If you miss a dose of Gabrico-Nt 400/10 Tab take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Taking too much of Gabrico-Nt 400/10 Tab may cause an overdose. Symptoms of overdose include drowsiness, weakness, double vision, unsteadiness when walking, dizziness, blurred vision, fever, and difficulty breathing. Consult the doctor if you experience these symptoms or if you have taken an overdose.

Gabrico-Nt 400/10 Tab may cause drowsiness and dizziness. Avoid driving or operating machinery until you know how this medicine affects you. Do not consume alcohol along with Gabrico-Nt 400/10 Tab as it could lead to increased dizziness and sleepiness.

You might need to visit your doctor on a regular basis. If the recommended dosage of Gabrico-Nt 400/10 Tab does not alleviate your symptoms or if you continue to have unpleasant side effects that interfere with your daily activities, you should speak with your physician.

Gabrico-Nt 400/10 Tab may cause drowsiness and sleepiness. Avoid driving or operating machinery until you know how this medicine affects you.

No, taking more than the recommended dose will not be more effective but cause unpleasant side effects. Therefore, do not exceed the recommended dose.

Store Gabrico-Nt 400/10 Tab at room temperature, in a dry place. Keep out of sight and reach of children.

No, you should avoid alcohol while taking Gabrico-Nt 400/10 Tab . Alcohol can greatly increase the drowsiness and dizziness caused by this medicine, which raises the risk of falls and accidents. Talk to your doctor if you have questions about alcohol use.

It may take several weeks of taking Gabrico-Nt 400/10 Tab daily before you notice a significant reduction in your nerve pain. Do not stop taking the medicine if you do not feel immediate relief. Talk to your doctor if your pain does not improve after a few weeks.

Yes, dry mouth is a frequent side effect of this medicine. You can manage this by sipping water throughout the day, sucking on ice chips, or chewing sugar-free gum to keep your mouth moist. Talk to your doctor or pharmacist if dry mouth becomes highly uncomfortable.

You should only take Gabrico-Nt 400/10 Tab during pregnancy or breastfeeding if your doctor decides that the medical benefit outweighs any potential risk to the baby. Always consult your healthcare provider before starting or stopping any medications while pregnant or nursing. Talk to your doctor to understand the risks.

Yes, Gabrico-Nt 400/10 Tab contains an active ingredient that can cause a rapid or irregular heartbeat, particularly in individuals with pre-existing heart conditions. If you experience chest pain, shortness of breath, or a pounding heart, seek immediate medical care. Talk to your doctor before starting this medicine if you have heart issues.

If you experience sudden changes in mood, worsening depression, anxiety, or thoughts of self-harm, contact your doctor or seek emergency medical help immediately. These emotional changes require prompt evaluation by a healthcare professional. Talk to your doctor to ensure your treatment is safe for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 020235S064 020882S047 021129S046Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. MedlinePlus. A682620 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Gabapentin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Drugs.com Clinical Review Team. Nortriptyline Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  5. Nortriptyline [EMC SmPC]. 2019. [Accessed on 25 Mar. 2019] Check here
  6. Gabapentin [Prescribing Information]. 2012. [Accessed on 22 Apr. 2019] Check here
  7. Gabapentin 400 mg capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 21 November 2021]Check here

Country of origin

India
Other Info - GAB0560

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