Gencef-S 1.5 Injection
MRP ₹222
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About Gencef-S 1.5 Injection
Gencef-S 1.5 Injection belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Gencef-S 1.5 Injection does not work against infections caused by the virus, including cold and flu.
Gencef-S 1.5 Injection is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, Gencef-S 1.5 Injection helps to treat bacterial infections.
You may experience diarrhoea, allergic reaction, abnormal liver function tests, and anaemia (low number of red blood cells). Most of these side effects of Gencef-S 1.5 Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Before starting Gencef-S 1.5 Injection, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Gencef-S 1.5 Injection on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Gencef-S 1.5 Injection if you are pregnant or planning for pregnancy. Avoid taking Gencef-S 1.5 Injection if you are breastfeeding as Gencef-S 1.5 Injection may pass into breast milk. Avoid alcohol consumption while taking Gencef-S 1.5 Injection to prevent unpleasant side-effects.
Uses of Gencef-S 1.5 Injection
Gencef-S 1.5 Injection is used in the treatment of bacterial infections. The detailed uses of Gencef-S 1.5 Injection are as follows:
- Treatment of Bacterial Infections: Gencef-S 1.5 Injection is effective against a wide range of bacterial infections, including those affecting the respiratory tract, urinary tract, skin, and soft tissues.
- Management of Intra-Abdominal Infections: Gencef-S 1.5 Injection is used to treat severe intra-abdominal infections, such as peritonitis and abscesses.
- Septicemia Treatment: Gencef-S 1.5 Injection is prescribed for managing septicemia, a life-threatening condition caused by harmful bacteria in the bloodstream.
- Bone and Joint Infections: Gencef-S 1.5 Injection is also used in treating severe infections of bones and joints, such as osteomyelitis and septic arthritis.
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Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication, to improve effectiveness.
- Gencef-S 1.5 Injection will be administered by a healthcare professional.
- Do not self-administer it.
Medicinal Benefits
Gencef-S 1.5 Injection belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Gencef-S 1.5 Injection is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, Gencef-S 1.5 Injection helps to treat bacterial infections.
How Gencef-S 1.5 Injection Works
Storage
- Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
- Avoid contact with people who are sick.
- Wash your hands regularly with soap and water.
- Avoid unpasteurized dairy products.
- Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
- Get sufficient sleep and manage stress which helps in improving white blood cell count.
- Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
- Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
- Stay hydrated by taking fluids like water, juices and soups etc.
- Eat fruits and vegetables which contain vitamins.
- Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
- Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
- Regular exercise like walking, jogging is helpful.
- Inform your doctor if you experience low hematocrit symptoms such as exhaustion, weakness, or pale complexion. Your doctor will diagnose the problem and recommend appropriate treatment.
- Increase iron intake with iron-rich foods like red meat, poultry, fish, beans, and fortified cereals.
- Consume vitamin C-rich foods such as citrus fruits, bell peppers, and tomatoes to improve iron absorption.
- Avoid tea and coffee since they can interfere with iron absorption.
- Don't smoke because it lowers the creation of red blood cells.
- Consume beetroot juice, as it is rich in iron and supports red blood cell production.
- Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
- Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
- Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
- Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
- If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
- In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
- Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
- If you experience severe bleeding or bruising, seek emergency medical attention immediately.
What if I have taken an overdose of Gencef-S 1.5 Injection
Drug Warnings
After taking Gencef-S 1.5 Injection if you have allergy-like symptoms including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor. Do not take Gencef-S 1.5 Injection if you have an allergy to Gencef-S 1.5 Injection, cephalosporins penicillin class of antibiotics as it may cause a skin rash, itching, and difficulty in breathing. People having liver disease or jaundice (yellowing of skin/eye) should not take Gencef-S 1.5 Injection, as it can damage your liver severely. You may have diarrhoea in some cases which can be managed by taking it with any probiotics and plenty of fluids. Do not take antacids along with Gencef-S 1.5 Injection; maintain a gap of 2-3 hours between both. Avoid alcohol consumption while taking Gencef-S 1.5 Injection to prevent unpleasant side-effects. Gencef-S 1.5 Injection may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.
Drug-Drug Interactions
Drug-Drug Interactions
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When BCG vaccine is used with Gencef-S 1.5 Injection, its effectiveness may be reduced.
How to manage the interaction:
Taking Gencef-S 1.5 Injection with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor
Taking Gencef-S 1.5 Injection and Rifampicin together may increase the risk of bleeding.
How to manage the interaction:
Although there is an interaction between Gencef-S 1.5 Injection and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
Probiotics should be taken after taking the full course of Gencef-S 1.5 Injection in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine.
Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
Avoid intake of alcoholic beverages with Gencef-S 1.5 Injection as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Gencef-S 1.5 Injection in fighting off infections.
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Alcohol
Caution
Avoid consuming alcohol while taking Gencef-S 1.5 Injection as it cause increased side effects.
Pregnancy
Caution
Please consult your doctor if you are pregnant, your doctor will prescribe Gencef-S 1.5 Injection only if the benefits outweigh the risks.
Breast Feeding
Caution
A small amount of Gencef-S 1.5 Injection may pass into breast milk. Avoid taking Gencef-S 1.5 Injection if you are breastfeeding unless prescribed.
Driving
Caution
Gencef-S 1.5 Injection may cause dizziness in some people, so it may affect your ability to drive.
Liver
Caution
Dose adjustment may be needed. Please consult your doctor before taking Gencef-S 1.5 Injection if you have liver impairment/liver disease.
Kidney
Caution
Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Gencef-S 1.5 Injection.
Children
Safe if prescribed
For children, Gencef-S 1.5 Injection is safe, Dose needs to be adjusted and recommended by a doctor.
Heart
Consult your doctor
Please inform your doctor if you have any pre-existing heart problems
Geriatrics
Consult your doctor
Limited information available for use of Gencef-S 1.5 Injection in elderly patients. Please consult your doctor.
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Reference
- https://www.ciplamed.com/printpdf/23647#:~:text=Skin%20and%20soft%20tissue%20infections,of%20the%20genital%20tract%208.&text=Because%20of%20the%20broad%20spectrum,with%20this%20antibiotic%20combination%20alone.
- https://tajpharmaindia.com/wp-content/uploads/2015/09/PIL-CEFOZONE-SULBACTAMCEFOPERAZONE-INJ.pdf
