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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Geneglim-M2 Tablet is used to treat type 2 diabetes. It contains Glimepiride and Metformin which works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE

Manufacturer/Marketer :

Geneaid Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Geneglim-M2 Tablet

Geneglim-M2 Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).

Geneglim-M2 Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Take Geneglim-M2 Tablet as prescribed by your doctor. You are advised to take Geneglim-M2 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of Geneglim-M2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Geneglim-M2 Tablet or any other medicines, please tell your doctor. Geneglim-M2 Tablet is not recommended for children. Avoid breastfeeding while taking Geneglim-M2 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Geneglim-M2 Tablet as it may harm the unborn baby. Avoid alcohol consumption with Geneglim-M2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Geneglim-M2 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Geneglim-M2 Tablet .

Uses of Geneglim-M2 Tablet

Geneglim-M2 Tablet is used in the treatment of type 2 diabetes mellitus. The detailed uses of Geneglim-M2 Tablet are as follows:
• Management of Type 2 Diabetes: Geneglim-M2 Tablet helps lower blood sugar levels in individuals diagnosed with type 2 diabetes.
• Improvement of Insulin Sensitivity: Geneglim-M2 Tablet enhances the action of insulin, making the body's tissues more responsive to it.
• Reduction of Cardiovascular Risks: Regular use of Geneglim-M2 Tablet can help reduce the risk of cardiovascular diseases in diabetic patients.
• Control of Blood Sugar Levels Post Meals: Geneglim-M2 Tablet assists in lowering postprandial blood sugar spikes, which is beneficial for overall diabetes management.

Directions for Use

Take Geneglim-M2 Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Medicinal Benefits

Geneglim-M2 Tablet contains Glimepiride and Metformin used to treat type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin, which helps remove sugar from the blood. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

How Geneglim-M2 Tablet Works

Geneglim-M2 Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Geneglim-M2 Tablet

Take Geneglim-M2 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include hypoglycaemia (low blood sugar) and lactic acidosis (buildup of lactic acid in the blood). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Geneglim-M2 Tablet or any other medicines, please tell your doctor. Geneglim-M2 Tablet is not recommended for children. Avoid breastfeeding while taking Geneglim-M2 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Geneglim-M2 Tablet as it may harm the unborn baby. Avoid alcohol consumption with Geneglim-M2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Geneglim-M2 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Geneglim-M2 Tablet . Beware of symptoms of hypoglycemia (low blood sugar), which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug-Drug Interactions

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MetforminMetrizamide
Critical
MetforminIobitridol
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Geneglim-M2 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Geneglim-M2 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIobitridol
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Geneglim-M2 Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Geneglim-M2 Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Geneglim-M2 Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Geneglim-M2 Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIofendylate
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Iofendylate with Geneglim-M2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Geneglim-M2 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Iopamidol with Geneglim-M2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopydol
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Iopydol with Geneglim-M2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Iomeprol with Geneglim-M2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIotroxic acid
Critical
How does the drug interact with Geneglim-M2 Tablet:
Co-administration of Iotroxic acid with Geneglim-M2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Geneglim-M2 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

  • Maintain healthy body weight as obesity is also related to the onset of diabetes.

  • Maintain a low-fat and low-sugar diet. Replace carbohydrates-containing foods with whole grains, fruits, and vegetables as carbohydrates turn to sugars leading to high blood sugar.

  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Geneglim-M2 Tablet Substitute

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Geneglim-M2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Geneglim-M2 Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Geneglim-M2 Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Geneglim-M2 Tablet if you are breastfeeding.

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Driving

Caution

Geneglim-M2 Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Geneglim-M2 Tablet .

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Liver

Caution

Take Geneglim-M2 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Geneglim-M2 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Geneglim-M2 Tablet is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

Geneglim-M2 Tablet is indicated in the treatment of type 2 diabetes mellitus.

Geneglim-M2 Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.

Geneglim-M2 Tablet may increase the risk of low blood sugar levels especially with alcohol intake, exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.

You are not recommended to stop taking Geneglim-M2 Tablet on your own as discontinuing Geneglim-M2 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Geneglim-M2 Tablet , please consult your doctor so that alternative medicine may be prescribed.

You are not recommended to take Geneglim-M2 Tablet with phenytoin as it may reduce the effect of Geneglim-M2 Tablet and increase blood sugar levels. However, please consult a doctor before using Geneglim-M2 Tablet with other medicines.

Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.

Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.

You are advised to take Geneglim-M2 Tablet for the duration recommended by the doctor.

Store Geneglim-M2 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Geneglim-M2 Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.

Geneglim-M2 Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus, also known as noninsulin-dependent diabetes mellitus.

Side effects of Geneglim-M2 Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Long-term use of Geneglim-M2 Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.

You are recommended to avoid consumption of alcohol with Geneglim-M2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Geneglim-M2 Tablet should be swallowed as a whole with water; do not crush, break or chew it.

Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Geneglim-M2 Tablet . Avoid drinking alcohol.

Other medicines should be taken with Geneglim-M2 Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Geneglim-M2 Tablet .

Country of origin

India

Manufacturer/Marketer address

949/4,Hira Moti Chambers,Golwad,Khadia, Ahmedabad,India.
Other Info - GEN0516

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