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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Glenza 160Mg Tab is used to treat prostate cancer. It contains Enzalutamide, an androgen receptor blocker (inhibitor) that blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow; this can slow the growth of the cancer and may shrink it. Enzalutamide is only for use in men. Men using this medication must use effective birth control whenever they have sex during their treatment and for three months after their final dose.

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Whats That

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Composition :

ENZALUTAMIDE-160MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Glenza 160Mg Tab

Glenza 160Mg Tab belongs to a group of medicines known as androgen receptor inhibitors. It is used to treat prostate cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Glenza 160Mg Tab contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Use this medicine as directed by your doctor. You may sometimes experience trouble breathing (pneumonia), weakness or feeling more tired than usual, back pain, diarrhoea, pain in your joints, swelling (in your hands, arms, legs or feet), muscle or bone pain, muscle weakness, headache, cold-like symptoms, dizziness, high blood pressure and trouble falling or staying asleep (insomnia). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Enzalutamide is only for use in men. Men using this Glenza 160Mg Tab must use effective birth control whenever they have sex during your treatment and for three months after their final dose. In rare cases, Glenza 160Mg Tab may cause seizures, so tell your doctor if you have or have ever had seizures. Because of the risk of seizure associated with Glenza 160Mg Tab use, patients should be advised of the risk of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Consumption of alcohol is strictly avoided.

Uses of Glenza 160Mg Tab

Treatment of Prostate Cancer

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush or chew it.

Solution: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Glenza 160Mg Tab contains Enzalutamide, which belongs to a group of medicines known as androgen receptor inhibitors. Most prostate cancers require testosterone to grow. In men, the testicles produce the majority of testosterone. Adrenal glands (Just above each kidney) produce a small quantity of testosterone. Enzalutamide is preventing testosterone from reaching cancer cells in the prostate. This can inhibit the growth of the cancer and even cause it to shrink.

How Glenza 160Mg Tab Works

Glenza 160Mg Tab contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Storage

Store in a cool and dry place away from sunlight
Side effects of Glenza 160Mg Tab
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.

What if I have taken an overdose of Glenza 160Mg Tab

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Glenza 160Mg Tab may include seizures. Seek immediate medical attention if you observe any symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Glenza 160Mg Tab if you are allergic or hypersensitive to any component present in it. You must take Enzalutamide according to the instructions your doctor or pharmacist gives you. You must take Enzalutamide exactly as prescribed by your doctor or pharmacist. You must take the correct dose, not more or less. Consult your healthcare team before discontinuing Glenza 160Mg Tab or missing a dose. Talk to your doctor before taking Glenza 160Mg Tab if you have severe allergic reactions to medicines or foods or suffer from any medical illness. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Drug-Drug Interactions

verifiedApollotooltip
EnzalutamideRegorafenib
Critical
EnzalutamideLurasidone
Critical

Drug-Drug Interactions

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EnzalutamideRegorafenib
Critical
How does the drug interact with Glenza 160Mg Tab:
Taking Glenza 160Mg Tab with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Glenza 160Mg Tab with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideLurasidone
Critical
How does the drug interact with Glenza 160Mg Tab:
Co-administration of Lurasidone with Glenza 160Mg Tab may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Glenza 160Mg Tab is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideDronedarone
Critical
How does the drug interact with Glenza 160Mg Tab:
Co-administration of Glenza 160Mg Tab and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Glenza 160Mg Tab and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideRanolazine
Critical
How does the drug interact with Glenza 160Mg Tab:
Taking Glenza 160Mg Tab may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Glenza 160Mg Tab with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideZiprasidone
Critical
How does the drug interact with Glenza 160Mg Tab:
Taking Glenza 160Mg Tab with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Glenza 160Mg Tab with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideBosutinib
Severe
How does the drug interact with Glenza 160Mg Tab:
Taking bosutinib with Glenza 160Mg Tab can decrease the blood levels of bosutinib, which decreases bosutinib's ability to treat your condition.

How to manage the interaction:
Although there is an interaction between Glenza 160Mg Tab and Bosutinib, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideLapatinib
Severe
How does the drug interact with Glenza 160Mg Tab:
When Lapatinib is taken with Glenza 160Mg Tab, this could reduce the effects of lapatinib and its blood levels. Additionally, taking these medications together may enhance Glenza 160Mg Tab's effects and blood levels.

How to manage the interaction:
Co-administration of Glenza 160Mg Tab with Lapatinib can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms - like Seizures, exhaustion, fatigue, constipation, discomfort in the muscles or bones, hot flushes, swelling, tingling or prickling, headaches, dizziness, sleeplessness, anxiety, and increased blood pressure, consult a doctor. Do not stop using any medications without talking to a doctor.
EnzalutamideTofacitinib
Severe
How does the drug interact with Glenza 160Mg Tab:
Co-administration of Glenza 160Mg Tab and Tofacitinib may decrease the blood levels of Tofacitinib, which may make Tofacitinib less effective.

How to manage the interaction:
Although taking Glenza 160Mg Tab and Tofacitinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.
EnzalutamideDelavirdine
Severe
How does the drug interact with Glenza 160Mg Tab:
Taking Glenza 160Mg Tab and Delavirdine together may decrease the blood levels of delavirdine, which may make delavirdine less effective in treating your HIV infection.

How to manage the interaction:
There may be a possibility of interaction between Glenza 160Mg Tab and Delavirdine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EnzalutamideHydrocodone
Severe
How does the drug interact with Glenza 160Mg Tab:
Taking Glenza 160Mg Tab with Hydrocodone may decrease the blood levels of Hydrocodone, which may make Hydrocodone less effective in treating pain.

How to manage the interaction:
Co-administration of Glenza 160Mg Tab with Hydrocodone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like watery eyes, a runny nose, sneezing, sweating heavily, fever, chills, flushing, restlessness, irritability, anxiety, depression, eye problems, shaking, rapid heartbeat, body pains, involuntary twitching and kicking, stomach pain, decreased hunger, nausea, vomiting, diarrhea, and weight loss, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Glenza 160Mg Tab Substitute

Substitutes safety advice
  • Enzyl 160 Tablet 7's

    by Others

    754.40per tablet
  • Azel 160 Tablet 7's

    by Others

    1019.09per tablet
  • Bdenza-160 mg Tablet 7's

    by Others

    900.00per tablet
  • Ca Enza-160 Tablet 7's

    by Others

    2407.14per tablet
  • Adleap Tablet 7's

    by Others

    687.63per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Glenza 160Mg Tab.

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Pregnancy

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Breast Feeding

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Driving

Caution

Glenza 160Mg Tab may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Consult your doctor

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Consult your doctor

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Glenza 160Mg Tab in pediatric patients have not been established.

Have a query?

FAQs

Glenza 160Mg Tab is used to treat prostate cancer in men.

Most prostate cancers require testosterone to grow. Glenza 160Mg Tab contains Enzalutamide, which blocks testosterone, a hormone, from reaching prostate cancer cells. Thus, Glenza 160Mg Tab can slow the cancer's growth and cause it to shrink.

Glenza 160Mg Tab is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.

In some cases, Glenza 160Mg Tab may cause decreased fertility in men. However, you should not assume that your female partner cannot become pregnant. Please discuss with your doctor if you have any concerns.

Enzalutamide, a prostate cancer medication, is used to treat prostate cancer.

Seizures may occur in patients receiving Glenza 160Mg Tab. So, patients who have had a seizure, please inform your doctor about your condition. Your doctor may monitor your condition closely.

Yes, Enzalutamide was generally a well-tolerated medication. Take Glenza 160Mg Tab pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Glenza 160Mg Tab unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Glenza 160Mg Tab therapy or adjust your Glenza 160Mg Tab dose.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - GLE0120

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