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compositionComposition:VANCOMYCIN-500MG
prescription
Prescription Medicine
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Gufivan 500Mg Injfusion is an antibiotic used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone). It contains Vancomycin, which prevents the formation of bacterial protective covering (cell wall) needed for their survival. Thus, it kills bacteria.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VANCOMYCIN-500MG

Manufacturer/Marketer :

Gufic Criti Care

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Gufivan 500Mg Injfusion

Gufivan 500Mg Injfusion is an injection used to treat serious bacterial infections. It is prescribed for severe infections of the skin, bones, lungs, and heart valves when other treatments may not work. This medication works by targeting and destroying the bacteria responsible for these deep-seated illnesses.

Because this medicine is injected directly into a vein, it is typically given on a strict schedule by a healthcare professional in a hospital or clinic setting. Since it enters the bloodstream directly, food intake does not affect how well it works. Getting plenty of rest and staying hydrated are highly recommended to support your body's natural recovery during treatment.

Common side effects include mild pain at the injection site or temporary skin flushing. If you experience severe issues like ringing in your ears, hearing changes, or a sudden decrease in urination, notify your doctor immediately. Your healthcare team will monitor you closely during each session to manage any potential reactions.

Talk to your doctor before starting this medicine if you have kidney problems or hearing difficulties. Do not take this if you have had a severe allergic reaction to this specific medication or similar antibiotics in the past. Your doctor will evaluate your medical history to ensure this is the safest treatment option for you.

Inform your healthcare provider about all other medicines you are taking, especially other antibiotics or water pills, as some combinations can increase the risk of kidney damage. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor to discuss the specific risks and benefits. Avoid alcohol and smoking during your treatment course to give your body the best chance to heal.

Uses of Gufivan 500Mg Injfusion

Gufivan 500Mg Injfusion is used to treat serious bacterial infections. The detailed uses of Gufivan 500Mg Injfusion are as follows:

  • Methicillin-resistant Staphylococcus aureus (MRSA) infections: Fights and clears severe, drug-resistant bacterial infections in various parts of the body.
  • Infections of the heart valves (endocarditis): Stops bacterial growth on the inner lining of the heart and its valves to prevent life-threatening complications.
  • Bone and joint infections: Penetrates deep tissues to eliminate bacteria causing painful infections in bone structures.
  • Severe skin and soft tissue infections: Treats deep-seated skin infections that do not respond to standard oral antibiotics.

Key Benefits

Gufivan 500Mg Injfusion helps treat serious bacterial infections by eliminating susceptible bacteria from the body. Administered intravenously, it delivers rapid and reliable antibiotic therapy for severe infections that require prompt medical treatment.

  • Helps Treat Serious Bacterial Infections: By targeting and eliminating infection-causing bacteria, Gufivan 500Mg Injfusion helps control severe bacterial infections and prevents them from spreading to other parts of the body.
  • Provides Rapid Therapeutic Action: Because it is administered directly into a vein, Gufivan 500Mg Injfusion reaches the bloodstream immediately, allowing prompt treatment for severe infections without relying on absorption through the digestive system.
  • Supports Faster Recovery and Prevents Complications: By effectively controlling the underlying infection, Gufivan 500Mg Injfusion helps reduce the risk of infection-related complications, supports recovery, and improves treatment outcomes when used under medical supervision.
Side effects of Gufivan 500Mg Injfusion
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Gufivan 500Mg Injfusion will be administered by a healthcare professional.
  • Do not self-administer.

How Gufivan 500Mg Injfusion Works

Gufivan 500Mg Injfusion contains vancomycin, which belongs to a group of medicines known as glycopeptide antibiotics. It works by preventing bacteria from building their outer protective walls. Bacterial cell walls are absolutely necessary for their survival and reproduction. By blocking the construction of these walls, the medicine causes the bacterial cells to weaken and rupture. This kills the bacteria, stops the infection from spreading, and allows your body's natural defences to clear the remaining illness.
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Alcohol

Caution

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

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Pregnancy

Caution

Please consult your doctor before taking Gufivan 500Mg Injfusion if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Gufivan 500Mg Injfusion can be excreted into breast milk when used by a nursing mother. Please consult your doctor before taking Gufivan 500Mg Injfusion if you are breastfeeding.

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Driving

Caution

There is limited data on how Gufivan 500Mg Injfusion affects your driving ability. Please seek medical advice for more information.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Gufivan 500Mg Injfusion. However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have any history of kidney problems. Your doctor will weigh the benefits and potential risks before prescribing Gufivan 500Mg Injfusion. However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Gufivan 500Mg Injfusion should be used for children only when prescribed by a doctor, depending on the child's age and body weight.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Caution

Gufivan 500Mg Injfusion can be administered in elderly patients with extreme caution, if prescribed by the physician.

What if I have taken an overdose of Gufivan 500Mg Injfusion

In the event of an accidental overdose, immediate medical attention is required. Seek emergency medical care right away.

Diet & Lifestyle Advise

  • Drink plenty of water and clear fluids throughout the day to support your kidney function while receiving this medicine.
  • Ensure you get adequate rest to allow your immune system to focus on clearing the infection.
  • Avoid alcohol during your treatment course to prevent extra strain on your body's organs.
  • Eat a balanced diet rich in vitamins to help rebuild your strength during and after a severe infection.
health query

Have a query?

How Soon It Starts Working

The time required for Gufivan 500Mg Injfusion to start to work: The time required for Gufivan 500Mg Injfusion to start to work is immediately after administration. The time for which the effects of Gufivan 500Mg Injfusion last: The effect of Gufivan 500Mg Injfusion lasts for 12 to 24 hours.

What if you forget to take Gufivan 500Mg Injfusion

Since this medicine is typically given by a healthcare provider, missed doses are highly unlikely. If you are receiving this treatment at home and miss a scheduled session, contact your doctor or home health nurse immediately to reschedule.

Storage

• Unopened vials of the powder should be stored at room temperature, between 20°C to 25°C (68°F to 77°F), away from direct light and moisture. Do not freeze the medicine.

Drug Warnings

  • Always inspect the liquid solution before injection; do not use it if it looks cloudy, discoloured, or contains visible particles.
  • Ensure the infusion is delivered slowly over at least one hour to reduce the risk of sudden redness and itching on your skin.
  • If you have a long-term intravenous line, rotate the injection site regularly to prevent vein irritation or infection.
  • Keep all appointments for blood tests, as your doctor will need to monitor your kidney health and the level of medicine in your blood.
  • Notify your healthcare provider immediately if you experience a metallic taste, dizziness, or any changes to your hearing.

Drug-Drug Interactions

verifiedApollotooltip
  • Aminoglycoside antibiotics, certain diuretics (water tablets), NSAIDs (e.g., ibuprofen, naproxen), and other medicines that can affect the kidneys or hearing: Taking these medicines together with Gufivan 500Mg Injfusion may increase the risk of kidney damage (nephrotoxicity) or hearing problems (ototoxicity). Your doctor may recommend closer monitoring of kidney function and hearing during treatment.
     
VancomycinCidofovir
Critical
VancomycinCytomegalovirus immunoglobulin
Severe

Drug-Drug Interactions

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VancomycinCidofovir
Critical
How does the drug interact with Gufivan 500Mg Injfusion:
Coadministration of Gufivan 500Mg Injfusion with Cidofovir can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Gufivan 500Mg Injfusion with Cidofovir is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you develop signs such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
VancomycinCytomegalovirus immunoglobulin
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Coadministration of Gufivan 500Mg Injfusion with Cytomegalovirus immunoglobulin can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Gufivan 500Mg Injfusion with Cytomegalovirus immunoglobulin may result in an interaction, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinIohexol
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Coadministration of Gufivan 500Mg Injfusion with Iohexol can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Gufivan 500Mg Injfusion with Iohexol may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinTeicoplanin
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Coadministration of Gufivan 500Mg Injfusion with Teicoplanin can increase the risk or severity of kidney and hearing problems.

How to manage the interaction:
Taking Gufivan 500Mg Injfusion with Teicoplanin may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience Breathlessness, decreased blood pressure, Wheezing, or Flushing (a sense of warmth in the face, ears, neck, and trunk). Do not discontinue any medication without consulting a doctor.
VancomycinIopamidol
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Taking Gufivan 500Mg Injfusion with Iopamidol can increase the risk of kidney damage.

How to manage the interaction:
Although taking Gufivan 500Mg Injfusion together with Iopamidol may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinIodamide
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Coadministration of Gufivan 500Mg Injfusion with Iodamide can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Gufivan 500Mg Injfusion with Iodamide may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinIoversol
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Taking Gufivan 500Mg Injfusion with Ioversol can increase the risk of kidney damage.

How to manage the interaction:
Although taking Gufivan 500Mg Injfusion together with Ioversol may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythms. Do not discontinue any medication without consulting a doctor.
VancomycinDeferasirox
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Coadministration of Gufivan 500Mg Injfusion with Deferasirox can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Gufivan 500Mg Injfusion with Deferasirox may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinCholera, live attenuated
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Taking Gufivan 500Mg Injfusion with Cholera, live attenuated reduces the activity of the vaccine.

How to manage the interaction:
Although taking Gufivan 500Mg Injfusion together with Adefovir dipivoxil may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience Breathlessness, decreased blood pressure, Wheezing, or Flushing (sense of warmth in the face, ears, neck and trunk). Do not discontinue any medication without consulting a doctor.
VancomycinIopromide
Severe
How does the drug interact with Gufivan 500Mg Injfusion:
Taking Gufivan 500Mg Injfusion with Iopromide can increase the risk of kidney damage.

How to manage the interaction:
Although taking Gufivan 500Mg Injfusion together with Iopromide may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Gufivan 500Mg Injfusion when used as directed. 
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Gufivan 500Mg Injfusion is used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone).
Gufivan 500Mg Injfusion contains Vancomycin which kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.
Gufivan 500Mg Injfusion can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Gufivan 500Mg Injfusion if you are undergoing any vaccinations.
Diarrhoea can be a side-effect of Gufivan 500Mg Injfusion. Clostridium difficile-associated diarrhoea (CDAD) is also reported during the usage of antibiotics like Gufivan 500Mg Injfusion. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Gufivan 500Mg Injfusion therapy.
While using Gufivan 500Mg Injfusion, caution should be exercised for patients with a history of kidney impairment, hearing problems, newborns, and the elderly population.
Yes, Gufivan 500Mg Injfusion is an antibiotic. It contains vancomycin as its active ingredient, which belongs to the class of medications called glycopeptide antibiotics.
The dose of Gufivan 500Mg Injfusion varies depending on the severity of the infection and the patient's condition. However, your doctor will determine the exact dose and duration based on your specific condition. Do not self-administer.
The common side effects of Gufivan 500Mg Injfusion are pain, redness, and swelling at the injection site. If any of these side effects persist or worsen, please consult your doctor.
For severe infections throughout the body, Gufivan 500Mg Injfusion must be given as an injection into a vein because the gut does not absorb it well enough to fight systemic infections. Talk to your doctor if you have questions about your treatment route.
Yes, temporary or permanent hearing loss and ringing in the ears can occur, especially if you receive high doses or have pre-existing kidney issues. Talk to your doctor immediately if you notice any changes in your hearing.
A sudden redness or flushing of the face, neck, and chest can happen if the medicine is injected too quickly. Your healthcare provider will monitor this and slow down the infusion rate. Talk to your doctor if this occurs.
This medicine is cleared from your body through your kidneys, and in some cases, it can cause kidney strain or damage. Your healthcare team will monitor your kidney function with regular blood tests. Talk to your doctor to learn more.
This medicine is typically used during pregnancy only if it is clearly needed for a severe infection. Your doctor will weigh the benefits against any potential risks to the developing baby. Talk to your doctor before receiving this medicine.
While many patients start their treatment in a hospital, some may continue their intravenous infusions at home under the supervision of a home health nurse. Talk to your doctor about your specific treatment plan.
No, this medicine only works against bacterial infections and will not treat viral illnesses like the flu or a common cold. Talk to your doctor if you suspect you have a viral infection.
A rash can be a sign of an allergic reaction or a reaction to a rapid infusion. You should contact your healthcare provider right away to have it evaluated. Talk to your doctor for safe management.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Other Info - GUF0015
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