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compositionComposition:LEVOCETIRIZINE-10MG
prescription
Prescription Medicine
info
Histacross L 10 mg Tablet 10's

HISTACROSS L-10MG TABLETS is used to treat various kinds of allergies, including hay fever (caused by pollen or dust), conjunctivitis (itchy eyes), eczema (dermatitis), hives (raised patches), reactions to insect bites and stings, and some food allergies. It contains Levocetirizine, which blocks histamine, a chemical that plays a key role in allergic reactions. Common side effects may include headaches, dry mouth, dizziness, stomach pain, sickness, and diarrhoea, but these usually resolve on their own. Before using this medicine, tell your doctor if you are allergic to any of its ingredients, have any existing medical conditions, or are taking other medications. Avoid taking this medicine with dairy products, as they may reduce its effectiveness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

LEVOCETIRIZINE-10MG

Manufacturer/Marketer :

Amwill Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About HISTACROSS L-10MG TABLETS

HISTACROSS L-10MG TABLETS is an antihistamine used to relieve symptoms associated with seasonal and year-round allergies. While many levocetirizine products are available without a prescription, it should be used according to the advice of a doctor or pharmacist. It is highly effective at treating sneezing, runny nose, itchy or watery eyes, and an itchy throat. Additionally, it is used to manage and relieve the itching and swelling associated with chronic hives of unknown cause.

To achieve the best results, you should take this medicine consistently once daily, or as directed by your healthcare provider. You can take it with or without food, though swallowing it with a glass of water is recommended. Combining this treatment with simple lifestyle adjustments, such as using an indoor air purifier and keeping windows closed during high-pollen seasons, can significantly improve your allergy management.

While taking HISTACROSS L-10MG TABLETS , you may experience mild side effects like drowsiness, dry mouth, or a mild headache. Most of these symptoms are temporary and resolve as your body adjusts, but you should contact your doctor immediately if you experience severe dizziness, difficulty urinating, or signs of a serious allergic reaction.

Before starting this medication, talk to your doctor if you have kidney disease, a history of urinary retention, or an enlarged prostate. Do not take this if you have severe kidney failure or are undergoing kidney dialysis, as your body will not be able to clear the medicine safely.

This medicine may interact with alcohol, sleeping pills, and muscle relaxants, which can significantly increase drowsiness and slow down your reaction times. Pregnant women, breastfeeding mothers, and elderly individuals should consult their doctor or pharmacist before starting HISTACROSS L-10MG TABLETS to ensure it is safe for their specific situation.

Uses of HISTACROSS L-10MG TABLETS

HISTACROSS L-10MG TABLETS is used to relieve allergy symptoms and manage chronic hives. The uses of HISTACROSS L-10MG TABLETS are as follows: 

  • Allergic rhinitis: HISTACROSS L-10MG TABLETS helps reduce seasonal and year-round allergy symptoms, including constant sneezing, a runny or itchy nose, and watery, itchy eyes.
  • Chronic hives: This medicine relieves the persistent skin itching, redness, and swelling associated with long-term hives.

Key Benefits

HISTACROSS L-10MG TABLETS helps provide effective relief from allergy symptoms by blocking the action of histamine, a substance responsible for allergic reactions. Its benefits include:

  • Provides 24-Hour Allergy Relief: Offers long-lasting relief from allergy symptoms with a single daily dose, helping you stay comfortable throughout the day and night.
  • Relieves Common Allergy Symptoms: Helps reduce sneezing, runny nose, itchy nose, watery eyes, and other symptoms associated with allergic conditions.
  • Supports Better Sleep: By helping prevent nighttime allergy symptoms, it may improve sleep quality and reduce sleep disturbances caused by allergies.
  • Causes Less Drowsiness: Compared with older antihistamines, HISTACROSS L-10MG TABLETS is less likely to cause significant drowsiness in most people, helping maintain daily productivity and alertness.
  • Works Quickly: Begins providing symptom relief within a short time after administration, helping deliver rapid comfort from allergy symptoms.
Side effects of Histacross L 10 mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

To get the most benefit from HISTACROSS L-10MG TABLETS , follow these step-by-step instructions carefully:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • If you are using the liquid form, shake the bottle well before use and measure your dose carefully using the provided measuring spoon or syringe, not a regular household spoon.
  • You can take this medicine with or without food, typically once a day in the evening, as it may cause mild drowsiness in some individuals.

Always follow your doctor's exact instructions regarding how and when to take this medicine, and do not adjust your dose without consulting them first.

How HISTACROSS L-10MG TABLETS Works

The active ingredient, levocetirizine, belongs to a class of medicines known as antihistamines. When your body encounters an allergen like pollen, dust, or pet dander, it releases a natural chemical called histamine. Histamine binds to specific receptors in your tissues, causing blood vessels to expand and fluids to leak, which leads to swelling, itching, sneezing, and a runny nose. This medicine works by selectively blocking these histamine receptors on the surface of your cells. By preventing histamine from binding to these sites, HISTACROSS L-10MG TABLETS stops the allergic cascade before these uncomfortable symptoms can develop. Because it crosses the blood-brain barrier to a much lesser extent than older first-generation antihistamines, it provides targeted allergy relief with a lower risk of causing significant drowsiness. However, some people may still experience sleepiness while taking this medicine.
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Alcohol

Unsafe

HISTACROSS L-10MG TABLETS may cause excessive dizziness when taken with alcohol so, together intake should be avoided.

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Pregnancy

Caution

HISTACROSS L-10MG TABLETS is pregnancy category B medicine so it can be used by the pregnant mother only if your doctor has prescribed it.

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Breast Feeding

Caution

HISTACROSS L-10MG TABLETS is known to pass on in a limited quantity via breast milk to the child. HISTACROSS L-10MG TABLETS should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Caution

Please drive with caution; HISTACROSS L-10MG TABLETS usually does not causes blurry vision, but it may affect driving ability in some.

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Liver

Safe if prescribed

Limited information was available for the use of HISTACROSS L-10MG TABLETS in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using HISTACROSS L-10MG TABLETS in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

HISTACROSS L-10MG TABLETS to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor. Patients with end-stage renal disease (ESRD) with less than 10 mL/min creatinine clearance or patients undergoing hemodialysis should not take HISTACROSS L-10MG TABLETS .

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Children

Safe if prescribed

It can be used in children, but the dosage and age restrictions depend on the specific formulation and the child's age.

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Heart

Consult your doctor

Limited data available for the use of HISTACROSS L-10MG TABLETS in heart patients. Please consult your physician.

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Geriatrics

Caution

HISTACROSS L-10MG TABLETS is safe for use in geriatric patients if prescribed by the physician.

What if I have taken an overdose of HISTACROSS L-10MG TABLETS

Do not take more than the prescribed dose of HISTACROSS L-10MG TABLETS as it may cause an overdose. The symptoms of overdose include agitation, drowsiness or restlessness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Control dust mites: Wash your bedding weekly in hot water and use allergen-proof covers on your pillows and mattresses to reduce allergen exposure.
  • Monitor pollen counts: Keep your windows closed and use air conditioning during high-pollen seasons, especially during dry, windy days.
  • Stay hydrated: Drink plenty of water throughout the day to help relieve dry mouth, a common side effect of antihistamines.
  • Use an air purifier: Install a HEPA filter air purifier in your bedroom to help trap airborne particles like pet dander and dust.
  • Clean nasal passages: Use a saline nasal rinse daily to physically wash away trapped pollen and dust from your nasal lining.

Have a query?

How Soon It Starts Working

The time required for HISTACROSS L-10MG TABLETS to start to work: HISTACROSS L-10MG TABLETS ideally shows its action within an hour after administration. The time for which the effects of HISTACROSS L-10MG TABLETS last: The effect of HISTACROSS L-10MG TABLETS lasts for 1 to 2 days.

What if you forget to take HISTACROSS L-10MG TABLETS

If you miss a dose of HISTACROSS L-10MG TABLETS , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store HISTACROSS L-10MG TABLETS tablets or oral liquid at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original container to protect it from moisture and direct light.

Drug Warnings

  • Test your reaction: Do not drive, operate heavy machinery, or perform dangerous tasks until you know how this medicine affects you, as it can cause drowsiness in some people.
  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it can severely compound drowsiness and impair your coordination.
  • Check the liquid: If using the liquid form, inspect the solution before taking it; it should be clear and free of particles.
  • Allergy testing prep: Stop taking this medicine at least several days before scheduled allergy skin tests, as antihistamines can prevent or reduce reaction markings, leading to inaccurate test results.
  • Monitor kidney function: If you have pre-existing kidney conditions, ensure your doctor monitors your kidney health regularly, as a lower dose may be required.

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with HISTACROSS L-10MG TABLETS : 

  • Central Nervous System Depressants: Taking HISTACROSS L-10MG TABLETS with medicines like sleeping pills, anxiety medications, muscle relaxants, or narcotic pain relievers can increase the risk of extreme drowsiness and slow breathing.
  • Other Antihistamines: Avoid using this medicine with other topical or oral antihistamines, as this can increase the risk of side effects like severe dry mouth and urinary issues.


Drug-Food Interactions

The following foods and beverages may interact with HISTACROSS L-10MG TABLETS and affect its safety or effectiveness:

  • Alcohol: Consuming alcohol while taking this medicine may significantly increase drowsiness, dizziness, and difficulty concentrating.


Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking HISTACROSS L-10MG TABLETS , as it may worsen your condition or require closer monitoring: 

  • Kidney Disease: Because this medicine is cleared by the kidneys, individuals with decreased kidney function may require an adjusted dose to prevent the drug from building up in the body.
  • Urinary Retention: If you have an enlarged prostate or difficulty urinating, this medicine may worsen your condition by further restricting urine flow.
LevocetirizineEsketamine
Severe

Drug-Drug Interactions

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LevocetirizineEsketamine
Severe
How does the drug interact with Histacross L 10 mg Tablet:
Using esketamine together with Histacross L 10 mg Tablet may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Taking Histacross L 10 mg Tablet with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIHISTAMINE]

FAQs

HISTACROSS L-10MG TABLETS is used to treat various types of allergies. It is commonly used for conditions like hay fever (caused by pollen or dust), allergic conjunctivitis (itchy or red eyes), eczema (dermatitis), hives (raised red patches), reactions to insect bites or stings, and some food allergies. It works by blocking histamine, a chemical in the body that causes allergic symptoms, helping to relieve sneezing, itching, runny nose, and watery eyes.
HISTACROSS L-10MG TABLETS contains levocetirizine (anti-histamine), which is used to treat allergies as it blocks the effects of a chemical messenger known as histamine, which is naturally involved in allergic reactions.
Hay fever is an allergy caused by outdoor or indoor allergens, such as pollen, dust mites, or tiny flecks of skin and saliva shed by cats, dogs, and other animals with fur or feathers (pet dander). It leads to cold-like symptoms (runny nose, watery eyes).
Depending upon the severity of allergic conditions due to allergens HISTACROSS L-10MG TABLETS can be safely taken daily until you get complete relief and as long as your doctor has advised you to take it.
HISTACROSS L-10MG TABLETS is an antihistamine providing instant relief from allergic conditions; however, in some people, it may cause sleepiness and induce some drowsiness during the day. Hence, you are recommended to take it at night if you experience excessive drowsiness during the day.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take HISTACROSS L-10MG TABLETS and skip the missed dose. Do not take extra medicine to make up the missed dose.
No, HISTACROSS L-10MG TABLETS should not be taken if you are intolerant to sugar; please contact your doctor before taking HISTACROSS L-10MG TABLETS to avoid any unpleasant side effects.
Yes, you can take HISTACROSS L-10MG TABLETS together with painkillers. However, it should be taken only if prescribed by the doctor only.
The side effects of HISTACROSS L-10MG TABLETS include dry mouth, headaches, tiredness, feeling sick, stomach pain and dizziness. If these side effects persist or worsen, please consult your doctor.
No, do not stop taking HISTACROSS L-10MG TABLETS without first consulting your doctor. If you discontinue in between the treatment, the symptoms of allergy may recur.
No, HISTACROSS L-10MG TABLETS is not an antibiotic. It is an anti-allergic medicine used for symptomatic relief from allergic conditions and rhinitis.
HISTACROSS L-10MG TABLETS starts working and shows improvement within 1 hour of taking it. However, to show full benefits, it may take a little longer.
You are recommended to consult your doctor before taking HISTACROSS L-10MG TABLETS with Fexofenadine or other medicines.
HISTACROSS L-10MG TABLETS is safe if it is used as advised by your doctor. Do not take it for longer durations or do not exceed the dose as it may increase the risk of side effects.
You are recommended to use HISTACROSS L-10MG TABLETS for as long as your doctor has prescribed it, and if you experience any difficulty while using HISTACROSS L-10MG TABLETS , please consult your doctor.
It is recommended to consult a doctor before taking HISTACROSS L-10MG TABLETS if you are pregnant or breastfeeding.
Store HISTACROSS L-10MG TABLETS at room temperature protected from light and moisture. Keep it out of reach and sight of children.
Generally, HISTACROSS L-10MG TABLETS does not interact with most blood pressure medications. However, it is always best to talk to your doctor or pharmacist to confirm safety with your specific prescriptions.
Seek emergency medical care or call your local poison control centre immediately if a child swallows this medicine by accident.
No, HISTACROSS L-10MG TABLETS is designed to treat symptoms caused by allergies, not the common cold. For cold symptom relief, talk to your doctor or pharmacist about appropriate treatments.
Because HISTACROSS L-10MG TABLETS can cause mild drowsiness in some people, many doctors recommend taking it in the evening. Talk to your doctor about the best schedule for your specific needs.
Yes, HISTACROSS L-10MG TABLETS may be prescribed for children, but the dose varies according to the child's age and the formulation being used. Children often require different doses from adults, so parents and caregivers should follow the advice of a doctor or pharmacist and use the appropriate measuring device for liquid preparations.
If your allergy symptoms remain uncontrolled, worsen, or continue despite regular use of HISTACROSS L-10MG TABLETS , consult your doctor. Further evaluation may be needed to confirm the cause of your symptoms or determine whether a different treatment approach is required.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.9917 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. National Health Service (NHS). Cetirizine - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Levocitirizine [EMC SmPC]. 2019. [Accessed on 01 Apr. 2019] Check here
  5. Levocitrizine [Product Information]. 2025. [Accessed on 19 Jan. 2026] Check here
  6. Levocetirizine dihydrochloride [Prescribing Information]. 2008. [Accessed on 20 Feb. 2024] Check here
  7. MONTAIR LC & MONTAIR LC KID DT / Syrup [Internet]. CiplaMed. 2021 [Accessed on 13th Aug 25]Check here

Country of origin

India

Manufacturer/Marketer address

No.157, 1st Floor, 2nd Main Road, 3rd Cross, Chamrajpet, Bangalore, Karnataka 560018 ? India.
Other Info - HIS0162

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