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compositionComposition:IMIPRAMINE-25MG
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Imicalm-25 mg Tablet 10's is used to treat depression. It contains Imipramine which increases the activity of certain natural substances (neurotransmitters) which regulate mood. Additionally, it is also used to treat bed-wetting at night in children aged 6 years and older by relaxing the urinary bladder muscles. This medicine may sometimes cause side effects such as dry mouth, nausea, vomiting, increased blood pressure, lack of coordination, swelling of the breast and weakness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IMIPRAMINE-25MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Imicalm-25 mg Tablet 10's

Imicalm-25 mg Tablet 10's is an oral prescription medication primarily used to treat depression. It helps restore the balance of certain natural chemicals in the brain, which improves mood and emotional well-being. In some cases, it is also prescribed to treat nighttime bedwetting in children.

To achieve the best results, you must take Imicalm-25 mg Tablet 10's consistently every day, often at bedtime, to help minimise daytime sleepiness. You can take this medicine with or without food, but taking it with a meal can help prevent a mild upset stomach. Combining this medication with healthy daily habits, such as regular sleep schedules and stress management, can significantly support your treatment progress.

While taking this medicine, you may experience mild temporary effects like dry mouth, mild sleepiness, or light dizziness. However, you should contact your healthcare provider immediately if you experience any serious side effects, such as a fast or irregular heartbeat, severe mood swings, or difficulty urinating.

Before starting this medication, tell your doctor if you have a history of heart problems, glaucoma, seizures, or difficulty urinating. Do not take this if you have recently had a heart attack or if you are currently taking certain other medications for depression. Your doctor will help determine if this treatment is safe for your specific health history.

This medicine can interact with alcohol, smoking, and medicines such as sleeping pills, which may increase drowsiness or affect how it works. If you are pregnant, breastfeeding, or elderly, consult your doctor before taking this medicine. Imicalm-25 mg Tablet 10's is generally avoided during the first trimester of pregnancy unless the expected benefit clearly outweighs the potential risk to the baby. It may also pass into breast milk, so your doctor will carefully weigh the benefits and risks before recommending its use during breastfeeding.

Uses of Imicalm-25 mg Tablet 10's

Imicalm-25 mg Tablet 10's is used in the treatment of depression and nocturnal enuresis (bed-wetting in children). The detailed uses of Imicalm-25 mg Tablet 10's are as follows:

  • Depression: Imicalm-25 mg Tablet 10's helps raise the levels of mood-regulating chemicals in the brain, relieving feelings of sadness, low energy, and anxiety in adults.
  • Nighttime bedwetting (nocturnal enuresis): It is used as a short-term treatment to help reduce bedwetting in children aged six and older when other non-drug therapies have not been successful.

Key Benefits

Imicalm-25 mg Tablet 10's helps relieve symptoms of depression and manage bedwetting in children, improving daily well-being and confidence.

The following are the benefits of Imicalm-25 mg Tablet 10's:

  • Helps improve mood and reduce symptoms of depression.
  • Increases energy levels and supports better daily functioning.
  • Improves focus and emotional well-being.
  • Reduces nighttime bedwetting episodes in children.
  • Supports better sleep and builds confidence in children with bedwetting.
  • Promotes long-term symptom control when taken as prescribed.
Side effects of Imicalm-25 mg Tablet
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.

Directions for Use

  • Always take Imicalm-25 mg Tablet 10's exactly as your doctor has prescribed.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medicine is released into your body.
  • You can take this medicine with or without food. If you experience stomach upset, taking it with a meal or a snack can help.
  • If you are taking it once daily, taking it at bedtime is often recommended to help prevent daytime sleepiness.
  • Always consult your doctor or pharmacist if you are unsure about how to take your dose.
  • Do not stop taking Imicalm-25 mg Tablet 10's suddenly. When it is time to stop treatment, your doctor will gradually reduce your dose over several weeks to help minimise withdrawal symptoms.

How Imicalm-25 mg Tablet 10's Works

Imicalm-25 mg Tablet 10's contains Imipramine, which belongs to a class of medicines known as tricyclic antidepressants. It works by blocking the reabsorption of two natural chemical messengers in the brain: norepinephrine and serotonin. By keeping more of these chemicals active in the brain, it helps improve communication between nerve cells, which lifts your mood and reduces anxiety. To help manage bedwetting, this medicine also blocks a chemical called acetylcholine. This action helps relax the muscle of the bladder wall while tightening the bladder outlet, making it easier to hold urine through the night.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Imicalm-25 mg Tablet 10's as it may cause increased drowsiness.

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Pregnancy

Caution

Imicalm-25 mg Tablet 10's belongs to pregnancy category C. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Imicalm-25 mg Tablet 10's may pass into breastmilk. Consult your doctor before taking Imicalm-25 mg Tablet 10's; your doctor will decide whether Imicalm-25 mg Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Imicalm-25 mg Tablet 10's may cause impaired alertness, drowsiness or blurred vision. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Imicalm-25 mg Tablet 10's is not recommended for children below 6 years as its safety and effectiveness have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Imicalm-25 mg Tablet 10's. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Imicalm-25 mg Tablet 10's can be given in elderly patients with extreme caution, if prescribed by the physician.

What if I have taken an overdose of Imicalm-25 mg Tablet 10's

If you suspect an overdose, seek emergency medical care immediately. An overdose of this medication can be life-threatening and requires urgent professional treatment. Common signs of an overdose may include severe sleepiness, rapid heartbeat, confusion, or seizures.

Diet & Lifestyle Advise

  • Manage dry mouth: Chew sugar-free gum, suck on ice chips, or sip water frequently throughout the day to keep your mouth moist.
  • Prevent constipation: Drink plenty of water and gradually increase your intake of dietary fibre, such as whole grains, fresh fruits, and vegetables.
  • Prevent dizziness: Take your time when standing up from a sitting or lying position to allow your blood pressure to adjust.
  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it can dangerously increase sleepiness and affect your coordination.
  • For bedwetting support: Limit your child's fluid intake in the evening, especially caffeinated or sugary beverages, and encourage them to use the bathroom right before bedtime.
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How Soon It Starts Working

  • The time required for Imicalm-25 mg Tablet 10's to start to work: Imicalm-25 mg Tablet 10's ideally shows its action within 2 weeks after administration.
  • The time for which the effects of Imicalm-25 mg Tablet 10's last: The effect of Imicalm-25 mg Tablet 10's lasts for 18 to 54 hours.

What if you forget to take Imicalm-25 mg Tablet 10's

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. If you take this medicine once daily at bedtime and miss your dose, do not take it the next morning; instead, contact your doctor or pharmacist for guidance. dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Imicalm-25 mg Tablet 10's out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not stop suddenly: Do not stop taking this medicine all of a sudden. Stopping quickly can cause withdrawal symptoms like nausea, headache, irritability, sleep problems, or flu-like symptoms. Your doctor will reduce the dose slowly if needed.
  • Be careful with driving: Avoid driving, cycling, or using heavy machinery until you know how this medicine affects your alertness. It may cause drowsiness or slow your reaction time.
  • Watch for mood changes: Pay close attention to any worsening depression, sudden mood changes, or suicidal thoughts, especially in the first few weeks or after dose changes. Contact your doctor immediately if these occur.
  • Protect your skin from the sun: Use sunscreen, wear sunglasses, and cover your skin when outdoors. This medicine can make your skin more sensitive to sunlight and increase the risk of sunburn.
  • Inform healthcare providers: Tell your dentist, surgeon, or any healthcare professional that you are taking this medicine before any procedure. It may interact with certain anaesthetics.

Drug-Drug Interactions

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  • Monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine, tranylcypromine): Do not take Imicalm-25 mg Tablet 10's with MAOIs, as this can cause extremely high blood pressure, high body temperature, and seizures. You must wait at least 14 days after stopping an MAOI before starting this medicine.
  • Central nervous system depressants (e.g., diazepam, zolpidem): Taking this medicine with sleeping pills, prescription pain relievers, or muscle relaxants can cause extreme drowsiness and dangerous breathing difficulties.
  • Heart medications (e.g., amiodarone, quinidine): Certain medicines used to treat abnormal heart rhythms can interact with Imicalm-25 mg Tablet 10's, increasing the risk of serious heart rhythm problems.

Drug-Drug Interactions

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How does the drug interact with Imicalm-25 mg Tablet:
Coadministration of Safinamide with Imicalm-25 mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking safinamide and Imicalm-25 mg Tablet together is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Imicalm-25 mg Tablet:
When Thioridazine and Imicalm-25 mg Tablet are taken together, the body's ability to break down Thioridazine may be reduced. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Imicalm-25 mg Tablet with Thioridazine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience extreme drowsiness, confusion, agitation, vomiting, blurred vision, feeling hot or cold, sweating, muscle stiffness, fainting, or seizure, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Imicalm-25 mg Tablet:
Using ziprasidone together with Imicalm-25 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Imicalm-25 mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Imicalm-25 mg Tablet:
Taking Sparfloxacin with Imicalm-25 mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sparfloxacin and Imicalm-25 mg Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Imicalm-25 mg Tablet:
Taking Imicalm-25 mg Tablet with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Imicalm-25 mg Tablet with Dronedarone together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Imicalm-25 mg Tablet:
Co-administration of Imicalm-25 mg Tablet with Selegiline might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Imicalm-25 mg Tablet and Selegiline together is not recommended as it can result in an interaction. It can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipraminePhenelzine
Critical
How does the drug interact with Imicalm-25 mg Tablet:
Coadministration of Imicalm-25 mg Tablet with Phenelzine might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Imicalm-25 mg Tablet and Phenelzine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Imicalm-25 mg Tablet:
Taking Tranylcypromine can increase the risk of Imicalm-25 mg Tablet on serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Imicalm-25 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Imicalm-25 mg Tablet:
Coadministration of Linezolid with Imicalm-25 mg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Linezolid and Imicalm-25 mg Tablet together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipraminePotassium citrate
Critical
How does the drug interact with Imicalm-25 mg Tablet:
Taking Imicalm-25 mg Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Potassium citrate and Imicalm-25 mg Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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  • Alcohol: Avoid drinking alcohol, as it can drastically worsen drowsiness, dizziness, and impair your motor skills while taking this medication.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[PSYCHOTHERAPEUTICS]

FAQs

Imicalm-25 mg Tablet 10's is used to treat depression. Additionally, it is also used to treat bed-wetting at night in children aged 6 years and older.
Imicalm-25 mg Tablet 10's works by increasing mood-enhancing chemical messengers (neurotransmitters) such as serotonin and norepinephrine in the brain that communicate between brain cells, thereby regulating mood and treating depression.
Do not discontinue Imicalm-25 mg Tablet 10's without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Imicalm-25 mg Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Imicalm-25 mg Tablet 10's. The doctor may reduce the dose gradually to prevent withdrawal symptoms.
Dry mouth could be a side-effect of Imicalm-25 mg Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Orthostatic hypotension could be a side-effect of Imicalm-25 mg Tablet 10's. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better.
Imicalm-25 mg Tablet 10's may cause photosensitivity or increased sensitivity to sunlight. Therefore, people taking Imicalm-25 mg Tablet 10's should avoid excessive exposure to sunlight or tanning beds. Use effective sunscreen and wear protective clothing while going outside.
Consult your doctor before taking Imicalm-25 mg Tablet 10's if you are diabetic, as Imicalm-25 mg Tablet 10's may cause elevation or lower blood glucose levels. Regularly monitor blood sugar levels while taking Imicalm-25 mg Tablet 10's.
Imicalm-25 mg Tablet 10's may make your open-angle glaucoma worse. Your doctor may monitor your vision while you are taking this medication.
Imicalm-25 mg Tablet 10's may affect blood sugar levels, especially in people with diabetes. It can cause fluctuations in blood sugar, so it's important to monitor your levels closely and consult your doctor for personalized advice.
Imicalm-25 mg Tablet 10's may cause weight gain in some people as it is an antidepressant that works by blocking certain neurotransmitters. This can lead to increased appetite and changes in metabolism, resulting in weight gain. Monitor your weight and discuss any changes with your doctor. They can adjust your medication or suggest lifestyle changes to manage this side effect.
Imicalm-25 mg Tablet 10's is not an addictive or habit-forming medication.
The common side effects of Imicalm-25 mg Tablet 10's you may experience are dry mouth, nausea, vomiting, increased blood pressure, lack of coordination, swelling of the breast, and weakness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
No, you should not stop taking Imicalm-25 mg Tablet 10's suddenly without consulting your doctor. Stopping abruptly can lead to withdrawal symptoms like nervousness, anxiety, and irritability.
Imicalm-25 mg Tablet 10's belongs to pregnancy category C medication, meaning it may be harmful to a fetus. Please consult your doctor before taking Imicalm-25 mg Tablet 10's if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Imicalm-25 mg Tablet 10's.
Store Imicalm-25 mg Tablet 10's in a cool, dry place away from sunlight. Keep it out of reach of children.
Imicalm-25 mg Tablet 10's may cause drowsiness or sleepiness, especially when first starting the medication or increasing the dosage. This sedative effect may decrease as your body adjusts to the medication. If it is not, consult the doctor.
If you forget a dose of Imicalm-25 mg Tablet 10's, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.
No, you should avoid alcohol while taking Imicalm-25 mg Tablet 10's. Alcohol can severely increase drowsiness and dizziness, and it can also interfere with how well the medicine treats your symptoms. Talk to your doctor.
Yes, Imicalm-25 mg Tablet 10's can be prescribed to children aged 6 and older for the short-term treatment of nighttime bedwetting when other treatments have not worked. Your child's doctor will determine the safest dose and monitor their progress closely. Talk to your doctor.
For most people, taking Imicalm-25 mg Tablet 10's at bedtime is recommended because it can cause drowsiness. However, your doctor will give you the best schedule based on why you are taking it and how it affects you. Talk to your doctor or pharmacist.

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Country of origin

India

Manufacturer/Marketer address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Other Info - IMI0083
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