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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Iminoral Solution is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CYCLOSPORINE-100MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Iminoral Solution

Iminoral Solution belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Iminoral Solution contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.

Iminoral Solution may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.

To treat your condition effectually, continue taking Iminoral Solution for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.

Uses of Iminoral Solution

Iminoral Solution is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Iminoral Solution are as follows:

  • Treatment of Organ Transplant Rejection: Iminoral Solution is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
  • Treatment of Psoriasis: Iminoral Solution is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
  • Treatment of Rheumatoid Arthritis: Iminoral Solution is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

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Directions for Use

  • Iminoral Solution can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions and use as advised by your doctor.
  • Measure the prescribed dose of Iminoral Solution using the dosing syringe. Mix it with apple or orange juice, stir well, and drink immediately.
  • Do not store the prepared mixture for later use.

Key Benefits

  • Iminoral Solution suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
  • It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
  • Iminoral Solution helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
  • It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
  • This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
  • It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
  • Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
  • It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.

How Iminoral Solution Works

Iminoral Solution contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation). Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

Storage

Store in a cool and dry place away from sunlight
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Increase protein intake by eating protein-rich foods like eggs, fish, lean meat, beans, and nuts to support nail strength.
  • Include biotin-rich foods like salmon, avocado, bananas, almonds, and whole grains in your diet to promote nail health.
  • Boost iron intake by consuming iron-rich foods like spinach, red meat, lentils, and fortified cereals to prevent iron deficiency.
  • Moisturize your nails and cuticles regularly by applying cuticle oil or hand cream multiple times a day.
  • Keep your nails short to reduce the risk of breakage and snagging.
  • Avoid biting your nails, as it can cause significant damage to your nails and cuticles.
  • Consider taking biotin supplements after consulting your doctor, as they may help strengthen brittle nails.

What if I have taken an overdose of Iminoral Solution

Do not take more than the prescribed dose of Iminoral Solution as it may cause an overdose. Symptoms of overdose include vomiting, drowsiness, headache, fast heartbeat, yellowing of the skin/eyes, and swelling of the arms, hands, feet, ankles, or lower legs. If you suspect you have taken an overdose or experience any of these symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not take Iminoral Solution if you are allergic to any of the components.
  • Let your doctor know before using Iminoral Solution if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
  • Iminoral Solution may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
  • Before taking Iminoral Solution, inform your doctor if you have any type of cancer.
  • Consult your doctor before taking Iminoral Solution if you are pregnant or planning for pregnancy.
  • Iminoral Solution should not be taken by breastfeeding mothers as it passes into breast milk.
  • Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Iminoral Solution 50 ml:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Iminoral Solution 50 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Iminoral Solution 50 ml:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Iminoral Solution 50 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
How does the drug interact with Iminoral Solution 50 ml:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Iminoral Solution 50 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Iminoral Solution 50 ml:
Coadministration of pitavastatin with Iminoral Solution 50 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Iminoral Solution 50 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Iminoral Solution 50 ml:
Combining Iminoral Solution 50 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Iminoral Solution 50 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Iminoral Solution 50 ml:
Co-administration of Clarithromycin with Iminoral Solution 50 ml may increase the effects of Iminoral Solution 50 ml.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Iminoral Solution 50 ml if prescribed by the doctor. Consult the prescriber if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, tremors, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
CiclosporinGolimumab
Severe
How does the drug interact with Iminoral Solution 50 ml:
Using Iminoral Solution 50 ml together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although taking golimumab and Iminoral Solution 50 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Iminoral Solution 50 ml:
When ambrisentan is taken with cyclosporine, this increases the blood levels of ambrisentan. This can increase the risk of serious side effects such as liver problems, anemia, and fluid accumulation (particularly in the lungs).

How to manage the interaction:
Co-administration of Iminoral Solution 50 ml with Ambrisentan can result in an interaction, but it can be taken if a doctor has advised it. If you experience any of these symptoms such as fever with shivering, pain in your joints, swelling, bleeding or bruising easily, a rash or itchy skin, not feeling hungry, feeling tired, dark color urine, looking pale, dizziness, gaining weight suddenly, or breathing problem, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Iminoral Solution 50 ml:
Using leflunomide together with Iminoral Solution 50 ml can increase the risk of side effects

How to manage the interaction:
Co-administration of Iminoral Solution 50 ml with leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience contact a doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, or pain during urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Iminoral Solution 50 ml:
Co-administration of Iminoral Solution 50 ml with mifepristone may significantly increase the blood levels of Iminoral Solution 50 ml which may increase the risk and/or severity of side effects.

How to manage the interaction:
Although taking Iminoral Solution 50 ml and Mifepristone together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you notice nausea, vomiting, diarrhea, abdominal discomfort, exhaustion, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, or increased or decreased urine, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar to prevent flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

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Alcohol

Safe if prescribed

You are recommended to avoid alcohol consumption while taking Iminoral Solution. It could lead to increased dizziness.

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Pregnancy

Consult your doctor

Iminoral Solution belongs to pregnancy category C. Consult your doctor before taking Iminoral Solution if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Iminoral Solution passes into breast milk. Avoid breastfeeding while taking Iminoral Solution.

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Driving

Safe if prescribed

Iminoral Solution may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Iminoral Solution is not recommended for children as efficacy and safety have not been established.

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Heart

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Iminoral Solution should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.

FAQs

Iminoral Solution is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis.

Iminoral Solution acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.

If you miss a dose of Iminoral Solution, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.

Diarrhoea might be a side effect of Iminoral Solution. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, the use of Iminoral Solution may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.

Iminoral Solution is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and using sunscreen regularly.

Iminoral Solution may cause high blood pressure. Therefore, consult the doctor before taking Iminoral Solution if you have high blood pressure.

No, Iminoral Solution is not a steroid. It is an immunosuppressant.

Iminoral Solution may cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight. Consult your doctor if you have any concerns.

Iminoral Solution may cause fatigue. Eat a healthy diet, get regular exercise, manage stress, improve sleep habits, and quit smoking. Doing these may help cope with fatigue.

Yes, your doctor will recommend certain tests to check your body’s response to Iminoral Solution.

Iminoral Solution may cause side effects like headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Talk to your doctor if you experience these side effects persistently.

Use the measuring cup/dosing syringe provided with the pack to measure the prescribed dose of Iminoral Solution. Mix the solution/suspension in a glass of milk or orange juice, stir well, and consume immediately. Do not store the prepared mixture for later use.

You are advised to take Iminoral Solution for the duration prescribed by the doctor. The duration of treatment will depend upon your condition and response to the treatment.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - IMI0072

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