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  3. Imodium Capsule 4's

Imodium Capsule 4's, Pack of 4 CAPSULES
Imodium Capsule 4's, Pack of 4 CAPSULES
Imodium Capsule 4's, Pack of 4 CAPSULES
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Composition :

LOPERAMIDE-2MG

Manufacturer/Marketer :

Janssen Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Imodium Capsule

Imodium Capsule is an anti-diarrhoeal medicine used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and in reducing the volume of discharge from ileostomies. Diarrhoea is a condition characterised by frequent bowel movements, resulting in loose, watery stools.

Imodium Capsule contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Imodium Capsule helps treat diarrhoea.

The most common side effects of Imodium Capsule are headache, nausea, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, reach out to your doctor.

Do not take Imodium Capsule if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Imodium Capsule may cause dizziness; therefore, do not drive unless you are alert. Keep the doctor informed about your health conditions and medications to help rule out any potential side effects or interactions.

Uses of Imodium Capsule

Imodium Capsule is used in the treatment of diarrhoea. The detailed uses of Imodium Capsule are as follows:
• Treatment of Diarrhoea: Imodium Capsule is effectively used to manage diarrhoea, including both acute and chronic cases.
• Reduction of Intestinal Motility: Imodium Capsule reduces intestinal movement, helping to alleviate gastrointestinal discomfort and related symptoms.
• Management of Irritable Bowel Syndrome (IBS): Imodium Capsule aids in controlling IBS symptoms, such as abdominal pain, bloating, and altered bowel habits.
• Support During Travel: Imodium Capsule is often taken as a preventive measure against travel-related diarrhoea, commonly referred to as traveller's diarrhoea.

Directions for Use

  • Imodium Capsule can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Imodium Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Imodium Capsule belongs to the class of anti-diarrhoeal medication used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and for reducing the volume of discharge from ileostomies. Imodium Capsule contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Imodium Capsule helps treat diarrhoea.

How Imodium Capsule Works

Imodium Capsule contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Imodium Capsule helps treat diarrhoea.

Storage

Store in a cool and dry place away from sunlight
Side effects of Imodium Capsule
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Imodium Capsule

Do not take more than the prescribed dose of Imodium Capsule as it may cause an overdose. The symptoms of overdose include irregular heartbeat, increased heart rate, uncoordinated movements, muscle stiffness, drowsiness, weak breathing or difficulty urinating. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Imodium Capsule if you are allergic to any of its components, if you have severe diarrhoea after taking antibiotics, ulcerative colitis, constipation, or acute dysentery (characterised by blood in the stools). Inform the doctor if you have AIDS and your stomach becomes swollen, liver or kidney disease, diarrhoea for more than 48 hours, severe diarrhoea, a history of drug abuse, slow or irregular heartbeat, low level of potassium in your blood, or prolonged QT interval (a rare heart problem). Seek immediate medical attention if you experience any of the following symptoms while taking loperamide: fast, irregular, or pounding heartbeat; dizziness; lightheadedness; unresponsiveness; or fainting. Avoid exceeding the recommended dosage, as it may lead to serious heart problems.

Drug-Drug Interactions

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LoperamideCiclosporin
Severe
LoperamideCimetidine
Severe

Drug-Drug Interactions

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LoperamideCiclosporin
Severe
How does the drug interact with Imodium Capsule:
Co-administration of Imodium Capsule with ciclosporin can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Although taking Imodium Capsule with Ciclosporin together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not exceed the dose and frequency or duration of use of Imodium Capsule advised by the doctor. Do not stop using any medications without talking to a doctor.
LoperamideCimetidine
Severe
How does the drug interact with Imodium Capsule:
When taken in combination cimetidine may considerably raise Imodium Capsule levels in the blood.

How to manage the interaction:
Although taking Imodium Capsule with cimetidine together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not exceed the dose and frequency or duration of use of Imodium Capsule advised by the doctor. Do not stop using any medications without talking to a doctor.
LoperamideDiltiazem
Severe
How does the drug interact with Imodium Capsule:
When taken in combination diltiazem may significantly raise the Imodium Capsule levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Imodium Capsule with diltiazem together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideAmprenavir
Severe
How does the drug interact with Imodium Capsule:
Co-administration of Imodium Capsule with amprenavir may raise blood levels of Imodium Capsule, you run the risk of developing major problems including abnormal heart rhythm. Other cardiac conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
Taking Imodium Capsule with Amprenavir together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
LoperamideAbiraterone
Severe
How does the drug interact with Imodium Capsule:
When taken in combination, abiraterone may considerably raise Imodium Capsule levels in the blood and cause irregular heart rhythm.

How to manage the interaction:
Although taking Imodium Capsule with abiraterone together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
LoperamideDronedarone
Severe
How does the drug interact with Imodium Capsule:
When taken in combination dronedarone may significantly raise the Imodium Capsule levels in the blood. This can lead to severe complications, such as abnormal heartbeat.

How to manage the interaction:
Although taking Imodium Capsule with dronedarone together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeats while taking these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
LoperamideFlibanserin
Severe
How does the drug interact with Imodium Capsule:
When taken in combination flibanserin may significantly raise the Imodium Capsule levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Imodium Capsule with flibanserin together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideRitonavir
Severe
How does the drug interact with Imodium Capsule:
Taking Imodium Capsule with ritonavir may significantly increase the blood levels of Imodium Capsule.

How to manage the interaction:
Although taking Imodium Capsule with ritonavir together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeats while taking these medications contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
LoperamideAmiodarone
Severe
How does the drug interact with Imodium Capsule:
Coadministration of Imodium Capsule with amiodarone can significantly increase Imodium Capsule levels which can increase the risk of a abnormal heart rhythm.

How to manage the interaction:
Taking Imodium Capsule with amiodarone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, rapid heartbeat, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
LoperamideTelithromycin
Severe
How does the drug interact with Imodium Capsule:
Co-administration of Imodium Capsule with telithromycin may raise blood levels of Imodium Capsule, you run the risk of developing major problems including abnormal heart rhythm. Other heart conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
Taking Imodium Capsule with Telithromycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids to stay hydrated.
  • Include bland foods such as bananas, rice, apples, cream of wheat, soda crackers, farina, applesauce, and toast to avoid aggravating the digestive system.
  • Avoid eating foods such as milk, dairy products, spicy foods, processed foods, pork, veal, sardines, raw vegetables, rhubarb, onions, corn, citrus fruits, alcohol, pineapples, cherries, seeded berries, grapes, caffeinated and carbonated drinks.
  • Eat fibre-rich food such as whole grains, lentils, beans, broccoli, and peas.
  • Wash your hands properly after using the toilet to prevent infections.
  • Clean the toilets regularly with a disinfectant.
  • Wash your hands thoroughly before eating, while preparing or serving.

Habit Forming

No

Therapeutic Class

ANTIDIARRHEALS

Imodium Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid/limit alcohol consumption as it may increase the side effects of this medicine, such as dizziness and drowsiness.

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Pregnancy

Caution

Loperamide belongs to pregnancy category C. It should be used during pregnancy only if the benefits outweigh the risks. Please consult the doctor if you are pregnant.

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Breast Feeding

Unsafe

Small amounts of Loperamide may appear in human breast milk. Therefore, it is not recommended during breastfeeding.

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Driving

Caution

Imodium Capsule may cause dizziness, tiredness or sleepiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Consult your doctor

No data is available in patients with liver impairment. Please consult the doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

No data is available in patients with renal impairment. Please consult the doctor if you have kidney problems or any concerns regarding this.

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Children

Caution

Imodium Capsule is contraindicated in children below 2 years due to the risk of heart and breathing problems. Please consult the doctor if you have any concerns regarding the usage of Imodium Capsule in children.

Have a query?

FAQs

Imodium Capsule is used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and in reducing the volume of discharge from ileostomies.

Imodium Capsule works by slowing down the movement of the bowel to decrease the number of bowel movements. It also helps lower the flow of fluids and electrolytes into the bowel.

Yes, diarrhoea may cause dehydration due to loss of fluid in stools. So, drink plenty of fluids/water to replace lost fluids due to diarrhoea. Talk to your doctor about rehydration therapy to replace lost salts.

Do not exceed the recommended dosage, as it may cause serious or life-threatening changes in your heart rhythm. Avoid taking a larger dose, taking it for a longer period of time, or taking it more often than prescribed by your doctor.

No, Imodium Capsule is not an antibiotic. It contains loperamide, which is an anti-diarrheal medication. Loperamide works by slowing down an overactive bowel and allowing the body to absorb water and salts usually lost in diarrhoea.

The duration of taking Imodium Capsule depends on the severity of your diarrhoea and your doctor's advice. Typically, it is taken for a short period or as directed by your doctor for chronic diarrhoea or inflammatory bowel disease. It's essential to follow your doctor's instructions and not exceed the recommended duration or dosage, as taking Imodium Capsule for longer than prescribed can lead to dependence or other side effects.

The effect of a single dose of Imodium Capsule typically lasts for 4 to 6 hours. However, this duration can vary depending on individual factors, such as the severity of diarrhoea, individual metabolism, and the presence of other medications or medical conditions. If symptoms persist or worsen, it's important to consult a healthcare provider for further guidance. Additionally, do not exceed the recommended dose or take Loperamide for longer than 2 days without medical advice.

Take Imodium Capsule for up to 2 days to manage acute diarrhoea. If symptoms persist or worsen, consult your healthcare provider. Do not take longer than recommended to avoid dependence and side effects.

Do not take Imodium Capsule with painkillers on your own. Only take it if recommended by your doctor. Combining medications without medical advice can be harmful. Always consult your healthcare provider before taking Imodium Capsule with painkillers or any other medications.

You can take probiotics with Imodium Capsule, but it's best to check with your doctor first. Probiotics can help alleviate diarrhoea and restore the balance of gut bacteria. Taking them with Imodium Capsule may make it work better and reduce side effects. However, consult your doctor to ensure safe and effective use, especially if you have a weakened immune system or take other medications.

Diarrhea is a common condition characterized by frequent bowel movements, loose or watery stools, and an urgent need to have a bowel movement. Various factors, including viral or bacterial infections, food intolerance or allergies, medications, digestive disorders, infections, and hormonal changes, can cause it. Suppose you experience persistent, severe, or bloody diarrhoea. In that case, seeking medical attention to determine the underlying cause and receive appropriate treatment is essential.

Take Imodium Capsule when you have acute diarrhoea or irritable bowel syndrome (IBS) with frequent diarrhoea. However, take it only if your doctor recommends it, for a short period (up to 2 days), and only if your symptoms are not severe. Also, do not take it if you have bloody stools, fever, or abdominal pain. Always follow the recommended dosage and consult your healthcare provider if symptoms persist or worsen.

A doctor will direct the dose of Imodium Capsule for adults, as it may vary depending on individual circumstances and medical history. Your doctor may adjust the dose based on your specific needs and response to treatment. Always follow your doctor's instructions and consult with them if you have any questions or concerns.

Yes, Imodium Capsule can be used to treat motions (diarrhoea). It is an anti-diarrheal medication that works by slowing down bowel movements and increasing the absorption of water and electrolytes from the intestines. This helps to firm up stool and reduce the frequency of bowel movements. However, it's important to note that Imodium Capsule should only be used under the guidance of a healthcare professional, especially if you have underlying medical conditions, are taking other medications, or are experiencing severe or persistent diarrhoea.

Imodium Capsule typically starts to work within 1-2 hours after taking it. It may take up to 4-6 hours to reach its full effect. However, this may vary depending on individual factors, such as the severity of diarrhoea and individual metabolism.

Imodium Capsule typically contains the active ingredient Loperamide Hydrochloride, an anti-diarrheal medication.

Imodium Capsule containing Loperamide Hydrochloride is generally considered safe when used as directed. However, as with all medications, it may cause side effects and interact with other medicines. To ensure safe use, follow the recommended dosage, inform your doctor about your medical history, and monitor for side effects.

Imodium Capsule can be used to treat diarrhoea and abdominal pain associated with Irritable Bowel Syndrome (IBS), but only under the guidance of a healthcare professional. While it can help manage symptoms, it's important to note that Loperamide may not address the underlying causes of IBS, and long-term use should be avoided. Your healthcare provider may also recommend other treatments or lifestyle changes to manage IBS symptoms.

Do not take Imodium Capsule with any other medication, including antibiotics, paracetamol, ibuprofen, omeprazole, ciprofloxacin, desmopressin, ritonavir, quinidine, or cotrimoxazole, unless advised by your doctor. Always consult your healthcare provider before combining medications to ensure safe and effective treatment.

Imodium Capsule can help with diarrhoea and stomach cramps during opiate withdrawal, but it's not a treatment for withdrawal itself. It can manage some symptoms, but it's important to remember that it doesn't address the underlying issues and shouldn't replace medically supervised treatment. Consult a healthcare professional for proper guidance and support during opiate withdrawal.

Imodium Capsule carries a low risk of addiction when used as directed by a healthcare professional to treat diarrhoea. However, taking high doses or using it for extended periods can increase the risk of habit formation and addiction. Individuals with a history of substance abuse or addiction should exercise caution.

Imodium Capsule can help alleviate diarrhoea caused by stomach flu, nausea, and some stomach cramps associated with diarrhoea. However, it's important to note that Imodium Capsule is not recommended for bloody diarrhoea, fever, gas, or rotavirus infections. In fact, anti-diarrheal medications like Loperamide are not recommended for rotavirus infections. Always consult a healthcare professional for proper diagnosis and treatment.

Imodium Capsule and cimetidine can be taken together. Cimetidine is an antacid and histamine-2 (H2) blocker that may not significantly interact with Loperamide. However, it's always best to consult your healthcare provider or pharmacist to ensure safe and effective treatment before taking any medications together.

Take Imodium Capsule only as directed by your doctor, based on your individual medical needs and condition. Follow the recommended dosage and frequency, and do not exceed the maximum dose prescribed. Always consult your doctor if you have any questions or concerns.

Yes, you can take Imodium Capsule for loose motion (diarrhoea). Imodium Capsule is commonly used to treat diarrhoea and reduce the frequency of loose stools. However, it's essential to consult your doctor before taking Loperamide, especially if you have any of the following: bloody or watery diarrhoea, fever, abdominal pain or cramping, or underlying medical conditions like inflammatory bowel disease (IBD). Remember, Imodium Capsule only treats symptoms, not the underlying cause of diarrhea. Your doctor will recommend the most suitable treatment based on your individual needs.

The most common side effects of Imodium Capsule are headache, nausea, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - IMO0001

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 2, 2025 | 10:57 AM IST

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Reference

  1. https://www.ditenate.al/en/products/pharmacy/digestive/diarrhea/loperamide-2-mg-20-tablets
  2. https://www.medicines.org.uk/emc/files/pil.12451.pdf
  3. https://medlineplus.gov/druginfo/meds/a682280.html
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/017694s052lbl.pdf
  5. https://www.drugs.com/loperamide.html

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