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compositionComposition:INDOMETHACIN-100MG
prescription
Prescription Medicine
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Inmeth Suppositories is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine used to relieve pain, swelling, and stiffness caused by osteoarthritis, ankylosing spondylitis, acute gouty arthritis, bursitis and/or tendinitis, and rheumatoid arthritis This medicine inhibits cyclo-oxygenase (COX) enzymes and thus helps reduce pain. Common side effects include headache, dizziness, indigestion, rectal pain, application site reactions, and nausea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

INDOMETHACIN-100MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Rectal

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Inmeth Suppositories

Inmeth Suppositories is a prescription medication used to relieve severe pain, swelling, and joint stiffness caused by moderate to severe arthritis and gout. It belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). Because this medicine is prepared as a rectal suppository, it is especially helpful for people who cannot take oral medications due to nausea or swallowing difficulties.

For this medicine to work effectively, it must be used consistently exactly as your doctor has prescribed. Some people may need to use it regularly to manage chronic joint swelling, while others might only use it for short periods during sudden pain flare-ups. To help improve your overall joint health and comfort, combining this treatment with gentle stretching, maintaining a healthy weight, and staying active is highly recommended.

While taking Inmeth Suppositories, you may experience mild side effects like local rectal irritation, minor stomach upset, or headaches. However, you should contact your doctor immediately if you notice serious symptoms such as severe abdominal pain, black or tarry stools, or sudden shortness of breath.

Do not take this if you have a history of severe allergic reactions to aspirin or other pain-relieving medicines, or if you have recent rectal bleeding or inflammation. It is also important to talk to your doctor before starting this medicine if you have high blood pressure, heart disease, kidney issues, or a history of stomach ulcers.

This medicine can interact with other substances; for instance, drinking alcohol while using it increases your risk of stomach bleeding. Always consult your doctor before using this medication if you are pregnant, planning to become pregnant, breastfeeding, or are over the age of 65, as your body may require special monitoring.

Uses of Inmeth Suppositories

Inmeth Suppositories is used to relieve severe pain, swelling, and joint stiffness caused by moderate to severe arthritis and gout. The detailed uses of Inmeth Suppositories are as follows:

  • Rheumatoid arthritis: Helps reduce painful joint swelling, morning stiffness, and inflammation in the joints.
  • Osteoarthritis: Eases chronic joint pain and improves physical mobility in daily life.
  • Ankylosing spondylitis: Relieves deep back pain and stiffness in the spine.
  • Acute gouty arthritis: Rapidly calms intense joint pain, redness, and swelling during sudden gout attacks.
  • Acute painful shoulder: Lowers inflammation and relieves pain caused by tendinitis or bursitis in the shoulder.

Key Benefits

Inmeth Suppositories provides effective relief from joint and muscle pain by reducing inflammation, swelling, and stiffness. With regular use as prescribed, it helps improve mobility and offers a convenient treatment option for patients who cannot take oral medicines.

  • Relieves Pain and Inflammation: By reducing inflammation, this medicine helps relieve severe joint and muscle pain, decrease swelling, and ease stiffness, allowing for more comfortable movement.
  • Improves Mobility: This medicine helps restore joint flexibility and range of motion, making everyday activities easier to perform with less discomfort.
    Convenient Rectal Administration: As a suppository, this medicine is a suitable option for patients who have difficulty swallowing tablets or are experiencing nausea or vomiting. It provides reliable pain relief while bypassing the stomach, making it particularly useful for managing nighttime pain and morning stiffness.
Side effects of Inmeth Suppositories
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • It is advised to use Inmeth Suppositories 2 to 4 times daily; however, follow your doctor's advice regarding the dosage and duration.
  • Lie down on your left side and raise your right knee to your chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. Hold it in place for a few moments.
  • Remain lying down for 5 minutes to prevent the suppository from coming out.

How Inmeth Suppositories Works

Inmeth Suppositories contains indomethacin, which works by targeting the biological sources of pain and swelling in your body. When you experience joint injury, arthritis, or gout, your body produces natural chemicals called prostaglandins, which trigger pain, heat, and swelling. This medication works by blocking the specific proteins (enzymes) that are responsible for making these prostaglandins. By lowering the level of these chemicals, Inmeth Suppositories effectively calms down inflammation, reduces swelling in the joints, and relieves pain, helping your body feel more comfortable.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Inmeth Suppositories. Alcohol intake, along with Inmeth Suppositories, may cause increased dizziness. It may also elevate the risk of stomach bleeding.

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Pregnancy

Unsafe

It is not recommended to use Inmeth Suppositories while you are pregnant. Please consult your doctor if you are pregnant or if you are having any concerns regarding this.

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Breast Feeding

Unsafe

It is not recommended to use Inmeth Suppositories while you are breastfeeding. Please consult your doctor if you are breastfeeding or if you are having any concerns regarding this.

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Driving

Caution

Inmeth Suppositories may cause dizziness. Do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Inmeth Suppositories is not recommended for children as efficacy and safety have not been established.

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Heart

Caution

Please talk to your doctor before using Inmeth Suppositories if you have pre-existing heart problems. Your doctor will prescribe Inmeth Suppositories if the benefits outweigh the risks.

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Geriatrics

Caution

Inmeth Suppositories should be used with caution in geriatric patients, as they may be more sensitive to side effects like stomach irritation or kidney problems. Please talk to your doctor before using Inmeth Suppositories.

What if I have taken an overdose of Inmeth Suppositories

If you suspect an overdose, or if someone has accidentally swallowed a suppository, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Avoid alcohol: Do not drink alcohol while using this medicine, as it significantly increases your risk of developing stomach bleeding or ulcers.
  • Stay hydrated: Drink plenty of water throughout the day to support your kidneys, as pain medications can affect kidney function.
  • Watch your diet: If you are using this for gout, limit foods high in purines, such as red meat, seafood, and sugary drinks, to prevent future flare-ups.
  • Keep moving gently: Engage in low-impact physical activities like swimming or cycling to maintain joint flexibility without causing joint strain.
health query

Have a query?

How Soon It Starts Working

The time required for Inmeth Suppositories to start to work: Inmeth Suppositories shows its effect within 1 hour after administration. The time for which the effects of Inmeth Suppositories last: Inmeth Suppositories effect last for 4 to 6 hours.

What if you forget to take Inmeth Suppositories

If you miss a dose, insert it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one entirely. Continue with your regular schedule. Do not use two suppositories at the same time to make up for a missed dose.

Storage

•Store Inmeth Suppositories suppositories in a cool place, ideally below 25°C (77°F).

Drug Warnings

  • This medication is strictly for rectal use; never swallow a suppository.
  • If the suppository is too soft to insert, chill it in its wrapper under cold water or in the fridge before opening.
  • Avoid taking other over-the-counter pain relievers (like ibuprofen or naproxen) at the same time, as this can increase your risk of side effects.
  • Check your blood pressure regularly, as NSAIDs can sometimes cause your blood pressure to rise.
  • Be careful when driving or using tools until you know how this medicine affects you, as it can sometimes cause dizziness.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin): May increase your risk of severe bleeding.
  • Other NSAIDs or aspirin: Can increase the risk of stomach ulcers and digestive tract bleeding.
  • Blood pressure medicines (such as ACE inhibitors or beta-blockers): Inmeth Suppositories may reduce how effectively these medicines lower your blood pressure.
  • Water pills (diuretics): Can increase the risk of kidney damage when used together.
IndometacinCidofovir
Critical
IndometacinKetorolac
Critical

Drug-Drug Interactions

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IndometacinCidofovir
Critical
How does the drug interact with Inmeth Suppositories:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Inmeth Suppositories with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndometacinKetorolac
Critical
How does the drug interact with Inmeth Suppositories:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Inmeth Suppositories with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinPrasugrel
Severe
How does the drug interact with Inmeth Suppositories:
Taking Indomethacin with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Taking Inmeth Suppositories with Prasugrel together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinDasatinib
Severe
How does the drug interact with Inmeth Suppositories:
Using Dasatinib together with Inmeth Suppositories may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Inmeth Suppositories with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience bruising, dizziness, red or black, tarry stools, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinDiclofenac
Severe
How does the drug interact with Inmeth Suppositories:
The combined use of diclofenac and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Diclofenac and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IndometacinMethotrexate
Severe
How does the drug interact with Inmeth Suppositories:
Co-administration of Methotrexate with Indomethacin can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Methotrexate and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
IndometacinAdefovir dipivoxil
Severe
How does the drug interact with Inmeth Suppositories:
Using Indomethacin with Adefovir dipivoxil can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Inmeth Suppositories with Adefovir dipivoxil can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you have nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, bone pain, muscle cramps, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medications without a doctor's advice.
IndometacinSulindac
Severe
How does the drug interact with Inmeth Suppositories:
The combined use of Inmeth Suppositories and Sulindac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and perforation.

How to manage the interaction:
Taking Inmeth Suppositories with Sulindac together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinKetoprofen
Severe
How does the drug interact with Inmeth Suppositories:
The combined use of Inmeth Suppositories and ketoprofen can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Inmeth Suppositories with Ketoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinRivaroxaban
Severe
How does the drug interact with Inmeth Suppositories:
Coadministration of Indomethacin with Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Taking Inmeth Suppositories with Rivaroxaban together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol as it increases the risk of stomach irritation and internal bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Inmeth Suppositories belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmeth Suppositories is also used to treat acute gouty arthritis and bursitis and/or tendinitis (painful shoulder).
Inmeth Suppositories works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.
Diarrhoea might be a side-effect of Inmeth Suppositories. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not take Inmeth Suppositories for longer durations or high doses as it may increase the risk of stomach bleeding. Do not exceed the dose and duration prescribed by your doctor.
Inmeth Suppositories may increase the risk of heart attack or stroke. Do not use Inmeth Suppositories immediately before or after heart surgery. Consult your doctor before using Inmeth Suppositories if you have/ had heart problems.
Inmeth Suppositories may affect laboratory test results. Inform the person doing the tests that you are using Inmeth Suppositories.
Inmeth Suppositories may affect fertility. However, the effect is reversible on stopping Inmeth Suppositories. Consult your doctor before using Inmeth Suppositories if you are planning to become pregnant.
No, you must never swallow these suppositories. They are specially formulated to be absorbed through the rectal lining. Swallowing them will not work correctly and can cause severe stomach upset. Talk to your doctor if you need an oral alternative.
If you have a history of stomach ulcers, you should be extremely cautious. Even though this medicine is inserted rectally, it still circulates through your bloodstream and can increase the risk of stomach bleeding. Talk to your doctor before using this medicine.
You should avoid using this medication during pregnancy, especially during the last three months, as it may harm the unborn baby or cause complications during delivery. Always talk to your doctor before using any medication while pregnant.
You should avoid taking other NSAIDs like ibuprofen, naproxen, or aspirin while using this medicine, as doing so greatly increases your risk of serious stomach and kidney side effects. Talk to your doctor or pharmacist before combining any pain relievers.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - INM0034

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