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compositionComposition:INDOMETHACIN-100MG
prescription
Prescription Medicine
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Inovig Suppositories 5's is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine used to relieve pain, swelling, and stiffness caused by osteoarthritis, ankylosing spondylitis, acute gouty arthritis, bursitis and/or tendinitis, and rheumatoid arthritis This medicine inhibits cyclo-oxygenase (COX) enzymes and thus helps reduce pain. Common side effects include headache, dizziness, indigestion, rectal pain, application site reactions, and nausea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

INDOMETHACIN-100MG

Manufacturer/Marketer :

Invig Healthcare Pvt Ltd

Consume Type :

Rectal

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Inovig Suppositories 5's

Inovig Suppositories 5's is a prescription medication used to relieve severe pain, swelling, and joint stiffness caused by moderate to severe arthritis and gout. It belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). Because this medicine is prepared as a rectal suppository, it is especially helpful for people who cannot take oral medications due to nausea or swallowing difficulties.

For this medicine to work effectively, it must be used consistently exactly as your doctor has prescribed. Some people may need to use it regularly to manage chronic joint swelling, while others might only use it for short periods during sudden pain flare-ups. To help improve your overall joint health and comfort, combining this treatment with gentle stretching, maintaining a healthy weight, and staying active is highly recommended.

While taking Inovig Suppositories 5's, you may experience mild side effects like local rectal irritation, minor stomach upset, or headaches. However, you should contact your doctor immediately if you notice serious symptoms such as severe abdominal pain, black or tarry stools, or sudden shortness of breath.

Do not take this if you have a history of severe allergic reactions to aspirin or other pain-relieving medicines, or if you have recent rectal bleeding or inflammation. It is also important to talk to your doctor before starting this medicine if you have high blood pressure, heart disease, kidney issues, or a history of stomach ulcers.

This medicine can interact with other substances; for instance, drinking alcohol while using it increases your risk of stomach bleeding. Always consult your doctor before using this medication if you are pregnant, planning to become pregnant, breastfeeding, or are over the age of 65, as your body may require special monitoring.

Uses of Inovig Suppositories 5's

Inovig Suppositories 5's is used to relieve severe pain, swelling, and joint stiffness caused by moderate to severe arthritis and gout. The detailed uses of Inovig Suppositories 5's are as follows:

  • Rheumatoid arthritis: Helps reduce painful joint swelling, morning stiffness, and inflammation in the joints.
  • Osteoarthritis: Eases chronic joint pain and improves physical mobility in daily life.
  • Ankylosing spondylitis: Relieves deep back pain and stiffness in the spine.
  • Acute gouty arthritis: Rapidly calms intense joint pain, redness, and swelling during sudden gout attacks.
  • Acute painful shoulder: Lowers inflammation and relieves pain caused by tendinitis or bursitis in the shoulder.

Key Benefits

Inovig Suppositories 5's provides effective relief from joint and muscle pain by reducing inflammation, swelling, and stiffness. With regular use as prescribed, it helps improve mobility and offers a convenient treatment option for patients who cannot take oral medicines.

  • Relieves Pain and Inflammation: By reducing inflammation, this medicine helps relieve severe joint and muscle pain, decrease swelling, and ease stiffness, allowing for more comfortable movement.
  • Improves Mobility: This medicine helps restore joint flexibility and range of motion, making everyday activities easier to perform with less discomfort.
    Convenient Rectal Administration: As a suppository, this medicine is a suitable option for patients who have difficulty swallowing tablets or are experiencing nausea or vomiting. It provides reliable pain relief while bypassing the stomach, making it particularly useful for managing nighttime pain and morning stiffness.
Side effects of Inovig Suppositories
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • It is advised to use Inovig Suppositories 5's 2 to 4 times daily; however, follow your doctor's advice regarding the dosage and duration.
  • Lie down on your left side and raise your right knee to your chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. Hold it in place for a few moments.
  • Remain lying down for 5 minutes to prevent the suppository from coming out.

How Inovig Suppositories 5's Works

Inovig Suppositories 5's contains indomethacin, which works by targeting the biological sources of pain and swelling in your body. When you experience joint injury, arthritis, or gout, your body produces natural chemicals called prostaglandins, which trigger pain, heat, and swelling. This medication works by blocking the specific proteins (enzymes) that are responsible for making these prostaglandins. By lowering the level of these chemicals, Inovig Suppositories 5's effectively calms down inflammation, reduces swelling in the joints, and relieves pain, helping your body feel more comfortable.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Inovig Suppositories 5's. Alcohol intake, along with Inovig Suppositories 5's, may cause increased dizziness. It may also elevate the risk of stomach bleeding.

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Pregnancy

Unsafe

It is not recommended to use Inovig Suppositories 5's while you are pregnant. Please consult your doctor if you are pregnant or if you are having any concerns regarding this.

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Breast Feeding

Unsafe

It is not recommended to use Inovig Suppositories 5's while you are breastfeeding. Please consult your doctor if you are breastfeeding or if you are having any concerns regarding this.

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Driving

Caution

Inovig Suppositories 5's may cause dizziness. Do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Inovig Suppositories 5's is not recommended for children as efficacy and safety have not been established.

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Heart

Caution

Please talk to your doctor before using Inovig Suppositories 5's if you have pre-existing heart problems. Your doctor will prescribe Inovig Suppositories 5's if the benefits outweigh the risks.

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Geriatrics

Caution

Inovig Suppositories 5's should be used with caution in geriatric patients, as they may be more sensitive to side effects like stomach irritation or kidney problems. Please talk to your doctor before using Inovig Suppositories 5's.

What if I have taken an overdose of Inovig Suppositories 5's

If you suspect an overdose, or if someone has accidentally swallowed a suppository, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Avoid alcohol: Do not drink alcohol while using this medicine, as it significantly increases your risk of developing stomach bleeding or ulcers.
  • Stay hydrated: Drink plenty of water throughout the day to support your kidneys, as pain medications can affect kidney function.
  • Watch your diet: If you are using this for gout, limit foods high in purines, such as red meat, seafood, and sugary drinks, to prevent future flare-ups.
  • Keep moving gently: Engage in low-impact physical activities like swimming or cycling to maintain joint flexibility without causing joint strain.
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Have a query?

How Soon It Starts Working

The time required for Inovig Suppositories 5's to start to work: Inovig Suppositories 5's shows its effect within 1 hour after administration. The time for which the effects of Inovig Suppositories 5's last: Inovig Suppositories 5's effect last for 4 to 6 hours.

What if you forget to take Inovig Suppositories 5's

If you miss a dose, insert it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one entirely. Continue with your regular schedule. Do not use two suppositories at the same time to make up for a missed dose.

Storage

•Store Inovig Suppositories 5's suppositories in a cool place, ideally below 25°C (77°F).

Drug Warnings

  • This medication is strictly for rectal use; never swallow a suppository.
  • If the suppository is too soft to insert, chill it in its wrapper under cold water or in the fridge before opening.
  • Avoid taking other over-the-counter pain relievers (like ibuprofen or naproxen) at the same time, as this can increase your risk of side effects.
  • Check your blood pressure regularly, as NSAIDs can sometimes cause your blood pressure to rise.
  • Be careful when driving or using tools until you know how this medicine affects you, as it can sometimes cause dizziness.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin): May increase your risk of severe bleeding.
  • Other NSAIDs or aspirin: Can increase the risk of stomach ulcers and digestive tract bleeding.
  • Blood pressure medicines (such as ACE inhibitors or beta-blockers): Inovig Suppositories 5's may reduce how effectively these medicines lower your blood pressure.
  • Water pills (diuretics): Can increase the risk of kidney damage when used together.
IndometacinKetorolac
Critical
IndometacinCidofovir
Critical

Drug-Drug Interactions

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IndometacinKetorolac
Critical
How does the drug interact with Inovig Suppositories:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Inovig Suppositories with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinCidofovir
Critical
How does the drug interact with Inovig Suppositories:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Inovig Suppositories with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndometacinGlimepiride
Severe
How does the drug interact with Inovig Suppositories:
Taking indomethacin with glimepiride may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with indomethacin if prescribed by the doctor. Consult the doctor if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat.
IndometacinLeflunomide
Severe
How does the drug interact with Inovig Suppositories:
Taking leflunomide together with indomethacin may raise the risk of liver damage.

How to manage the interaction:
Although there is an interaction, indomethacin can be taken with Leflunomide, if prescribed by the doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult a doctor.
IndometacinFlucytosine
Severe
How does the drug interact with Inovig Suppositories:
Coadministration of Flucytosine with Indomethacin can increase the risk of developing infections.

How to manage the interaction:
Although there is a possible interaction between Flucytosine and Inovig Suppositories, you can take these medicines together if prescribed by your doctor. Contact a doctor if you experience fever, muscle ache, sore throat, or shortness of breath. Do not stop using any medications without a doctor's advice.
IndometacinDabigatran etexilate
Severe
How does the drug interact with Inovig Suppositories:
Using Indomethacin with Dabigatran etexilate can increase the risk of bleeding.

How to manage the interaction:
Taking Inovig Suppositories with Dabigatran etexilate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinSirolimus
Severe
How does the drug interact with Inovig Suppositories:
Co-administration of Indomethacin with Sirolimus can increase the risk or severity of kidney damage.

How to manage the interaction:
Although taking Inovig Suppositories and Sirolimus together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, breathing difficulty, muscle cramps, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
IndometacinRivaroxaban
Severe
How does the drug interact with Inovig Suppositories:
Coadministration of Indomethacin with Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Taking Inovig Suppositories with Rivaroxaban together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinValdecoxib
Severe
How does the drug interact with Inovig Suppositories:
The combined use of Inovig Suppositories and valdecoxib can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and perforation.

How to manage the interaction:
There may be a possibility of interaction between Inovig Suppositories and Valdecoxib, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
IndometacinKetoprofen
Severe
How does the drug interact with Inovig Suppositories:
The combined use of Inovig Suppositories and ketoprofen can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Inovig Suppositories with Ketoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol as it increases the risk of stomach irritation and internal bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Inovig Suppositories 5's belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inovig Suppositories 5's is also used to treat acute gouty arthritis and bursitis and/or tendinitis (painful shoulder).
Inovig Suppositories 5's works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.
Diarrhoea might be a side-effect of Inovig Suppositories 5's. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not take Inovig Suppositories 5's for longer durations or high doses as it may increase the risk of stomach bleeding. Do not exceed the dose and duration prescribed by your doctor.
Inovig Suppositories 5's may increase the risk of heart attack or stroke. Do not use Inovig Suppositories 5's immediately before or after heart surgery. Consult your doctor before using Inovig Suppositories 5's if you have/ had heart problems.
Inovig Suppositories 5's may affect laboratory test results. Inform the person doing the tests that you are using Inovig Suppositories 5's.
Inovig Suppositories 5's may affect fertility. However, the effect is reversible on stopping Inovig Suppositories 5's. Consult your doctor before using Inovig Suppositories 5's if you are planning to become pregnant.
No, you must never swallow these suppositories. They are specially formulated to be absorbed through the rectal lining. Swallowing them will not work correctly and can cause severe stomach upset. Talk to your doctor if you need an oral alternative.
If you have a history of stomach ulcers, you should be extremely cautious. Even though this medicine is inserted rectally, it still circulates through your bloodstream and can increase the risk of stomach bleeding. Talk to your doctor before using this medicine.
You should avoid using this medication during pregnancy, especially during the last three months, as it may harm the unborn baby or cause complications during delivery. Always talk to your doctor before using any medication while pregnant.
You should avoid taking other NSAIDs like ibuprofen, naproxen, or aspirin while using this medicine, as doing so greatly increases your risk of serious stomach and kidney side effects. Talk to your doctor or pharmacist before combining any pain relievers.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No.8, It Park Rd, Mansa Devi Complex, Rajeev Vihar, Rail Vihar, Mansa Devi Temple Complex, Panchkula, Haryana 134112
Other Info - INO0107

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