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compositionComposition:PALIPERIDONE-150MG
prescription
Prescription Medicine
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Invega Sustenna 150 mg Injection is used for the treatment of schizophrenia and schizoaffective disorder in adults. It contains Paliperidone, which works by blocking the effects of chemical messengers in the brain (i.e., dopamine and serotonin), thereby helping improve mood, behaviour and thoughts. Thus, it elevates the symptoms of the disease and prevents them from recurring. Common side effects of Invega Sustenna 150 mg Injection are injection site reactions, sleepiness or drowsiness, feeling restlessness or needing to be constantly moving, dizziness, abnormal muscle movements including tremors (shaking), uncontrolled involuntary movements, shuffling and abnormal movements of your eyes.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PALIPERIDONE-150MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Invega Sustenna 150 mg Injection

Invega Sustenna 150 mg Injection belongs to a group of medicines called 'antipsychotics' used for the treatment of schizophrenia and schizoaffective disorder in adults as monotherapy and as an adjunct to mood stabilizers or antidepressants. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

Invega Sustenna 150 mg Injection contains 'Paliperidone' that works by blocking the effects of chemical messengers in the brain (i.e., dopamine and serotonin), thereby helping improve mood, behaviour and thoughts. Invega Sustenna 150 mg Injection elevates the symptoms of the disease and prevents them from recurring.

Invega Sustenna 150 mg Injection is for intramuscular injection only. It should be given by experienced healthcare professionals. In some cases, you may experience common side effects such as injection site reactions, sleepiness or drowsiness, feeling restlessness or needing to be constantly moving, dizziness, abnormal muscle movements including tremor (shaking), uncontrolled involuntary movements, shuffling and abnormal movements of your eyes. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Invega Sustenna 150 mg Injection is restricted to use in people who are sensitive to paliperidone, risperidone, or any excipients in the formulation. Keep your doctor informed about your health condition and medicines to rule out any side effects. Before using Invega Sustenna 150 mg Injection , inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Invega Sustenna 150 mg Injection is recommended not to use in children. Avoid consuming alcohol with Invega Sustenna 150 mg Injection as it could lead to increased drowsiness and dizziness. Invega Sustenna 150 mg Injection may impair your ability to make judgements, think clearly, or respond fast. Do not drive, operate heavy machinery, or engage in any other risky activity.

Uses of Invega Sustenna 150 mg Injection

Invega Sustenna 150 mg Injection is used in the treatment of Schizophrenia. The detailed uses of Invega Sustenna 150 mg Injection are as follows:

  • Treat schizophrenia: Invega Sustenna 150 mg Injection is primarily used to manage symptoms of schizophrenia, such as hallucinations, delusions, and disorganized thinking, by balancing dopamine and serotonin levels in the brain.
  • Manage schizoaffective disorder: Invega Sustenna 150 mg Injection helps control mood disturbances and psychotic symptoms in patients with schizoaffective disorder, offering long-term stabilization.

Key Benefits

Invega Sustenna 150 mg Injection belongs to a group of medicines called antipsychotics used to treat schizophrenia in adults. Invega Sustenna 150 mg Injection improves mood and behaviour in people with an imbalance of chemicals known as neurotransmitters in their brains. Thus, Invega Sustenna 150 mg Injection relieves psychotic symptoms like delusions, hallucinations, confusion, disturbing thoughts and lack of self-awareness.

Side effects of Invega Sustenna 150 mg Injection 1.5 ml
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Managing Medication-Triggered very low levels of granulocytes (while blood cells): A Step-by-Step Guide:
  • If you take medicine and develop symptoms such as fever, chills, or serious infections, seek immediate medical attention. This could indicate neutropenia, a disorder marked by extremely low quantities of granulocytes (white blood cells).
  • To address the adverse effect, your doctor may change your treatment plan, offer supportive therapy, or prescribe other medications. They will also conduct regular blood tests to check your white blood cell level and adjust your medication as necessary.
  • Follow your doctor's advice, including dietary recommendations and lifestyle changes, and take steps to prevent infections, such as washing your hands frequently, avoiding close contact with sick people, and avoiding crowded areas.
  • Monitor your condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Discuss with your doctor if you suspect a medicine is causing hyperprolactinemia. Your doctor may reduce the dose or switch to an alternative medicine with low impact on prolactin levels.
  • Assess the severity of your symptoms related to high prolactin levels, like sexual dysfunction in men and menstrual irregularities in women for treatment choices.
  • Regular blood tests are recommended to monitor prolactin levels to assess treatment effectiveness.
  • Eat smaller meals and chew food thoroughly.
  • Try foods with softer textures.
  • If you have difficulty swallowing liquids, use thickener.
  • Learn new swallowing techniques from a speech and language therapist.
  • Avoid alcohol and caffeine as these may dry your throat and mouth making it more difficult to swallow.
  • Consider alternative forms of feeding, such as feeding tubes through nose or a hole into your stomach.
  • Avoid holding and empty the bladder at regular intervals.
  • Apply cold or ice packs for few minutes.
  • Exercise regularly and maintain a healthy lifestyle.
  • Make sure to have an adequate sleep.
  • Maintain healthy diet containing fruits and vegetables.

Directions for Use

  • Invega Sustenna 150 mg Injection is administered by healthcare professionals in a clinical setting, usually through an intramuscular injection.
  • The dosage and frequency are determined by your doctor, based on the severity of your condition and response to treatment.
  • Do not self-administer this injection, as improper use can cause serious side effects.
  • You may need to be monitored regularly by your doctor during treatment to check for any potential side effects and ensure the medication is effective.

How Invega Sustenna 150 mg Injection Works

Invega Sustenna 150 mg Injection contains 'Paliperidone' that works by blocking the effects of chemical messengers in the brain (i.e., dopamine and serotonin), thereby helping improve mood, behaviour and thoughts. Invega Sustenna 150 mg Injection elevates the symptoms of the disease and prevents them from recurring.
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Alcohol

Caution

Avoid consumption of alcohol while taking Invega Sustenna 150 mg Injection as it may cause increased drowsiness and lower your blood pressure.

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Pregnancy

Caution

Invega Sustenna 150 mg Injection is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Invega Sustenna 150 mg Injection .

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Breast Feeding

Caution

Caution should be exercised. Invega Sustenna 150 mg Injection is not recommended for use in breastfeeding unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Invega Sustenna 150 mg Injection .

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Driving

Unsafe

Invega Sustenna 150 mg Injection may affect your ability to make decisions, think clearly, or react quickly. Do not drive, operate heavy machinery, or do other dangerous activities.

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Liver

Caution

Inform your doctor if you have a liver impairment. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Inform your doctor if you have kidney impairment. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

The safety and efficacy of Invega Sustenna 150 mg Injection are not established in children under the age of 18 years.

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Heart

Caution

Inform your doctor if you have heart problems. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Invega Sustenna 150 mg Injection in elderly patients.

What if I have taken an overdose of Invega Sustenna 150 mg Injection

As Invega Sustenna 150 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Invega Sustenna 150 mg Injection may cause obtundation, seizures, and dystonic reactions of the head and neck following an overdose, which may create a risk of aspiration with induced emesis.

Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.
health query

Have a query?

How Soon It Starts Working

The time required for Invega Sustenna 150 mg Injection to start to work: The exact onset time of Invega Sustenna 150 mg Injection has not been clinically established. The time for which the effects of Invega Sustenna 150 mg Injection last: Invega Sustenna 150 mg Injection effect lasts for several days.

What if you forget to take Invega Sustenna 150 mg Injection

If you miss a dose, contact your healthcare provider to reschedule your next dose as needed.

Storage

• Store in a cool and dry place away from sunlight. • Keep Invega Sustenna 150 mg Injection out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Let your doctor know before prescribing Invega Sustenna 150 mg Injection if you are sensitive to paliperidone, risperidone, or any excipients in the formulation. Keep your doctor informed about your health condition and medicines to rule out any side effects. Before using the Invega Sustenna 150 mg Injection , inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Invega Sustenna 150 mg Injection is recommended not to use in children. Avoid consuming alcohol with Invega Sustenna 150 mg Injection as it could lead to increased drowsiness and dizziness. Invega Sustenna 150 mg Injection has the potential to impair your capacity to make judgements, think clearly, or respond swiftly. Avoid being dehydrated or overheated.

Drug-Drug Interactions

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Drug-Drug Interactions: Invega Sustenna 150 mg Injection may have interaction with antipsychotic medicines (e.g. haloperidol), medicines used to treat anxiety and sleeping problems (e.g. lorazepam), anti-depression medications (e.g. duloxetine), anti-allergic medications (e.g. diphenhydramine) and medicines used to treat schizophrenia and bipolar disorder (aripiprazole).

Drug-Food Interactions: Invega Sustenna 150 mg Injection may interact with alcohol. Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Invega Sustenna 150 mg Injection may have interactions with disease conditions including dementia (memory loss), irregular heartbeat (with QT interval prolongation), Neuroleptic Malignant Syndrome, aspiration, seizure, hematologic abnormalities, hyperglycemia/diabetes, hypotension, lipid alterations, priapism, weight gain, depression, hyperprolactinemia, tardive dyskinesia, antiemetic effect and gastrointestinal obstruction.

PaliperidoneZiprasidone
Critical
PaliperidoneMoxifloxacin
Severe

Drug-Drug Interactions

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PaliperidoneZiprasidone
Critical
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
Using Invega Sustenna 150 mg Injection 1.5 ml with Ziprasidone can increase the risk of irregular heart rhythm,.

How to manage the interaction:
Taking Ziprasidone with Invega Sustenna 150 mg Injection 1.5 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
PaliperidoneMoxifloxacin
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
Using Moxifloxacin together with Invega Sustenna 150 mg Injection 1.5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Invega Sustenna 150 mg Injection 1.5 ml together can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heartbeats, dizziness, trouble breathing call a doctor right away. Do not stop using any medications without a doctor's advice.
PaliperidoneChloroquine
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
Taking chloroquine and Invega Sustenna 150 mg Injection 1.5 ml together can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking chloroquine and Invega Sustenna 150 mg Injection 1.5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PaliperidonePhenytoin
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
Coadministration of Phenytoin and Invega Sustenna 150 mg Injection 1.5 ml may reduce the blood levels of Invega Sustenna 150 mg Injection 1.5 ml.

How to manage the interaction:
Co-administration of Phenytoin with Invega Sustenna 150 mg Injection 1.5 ml can result in an interaction, but it can be taken if your doctor has advised it. When taken together, the doctor can recommend other options that won't cause any problems. Do not stop using any medications without a doctor's advice.
PaliperidoneDisopyramide
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
The combined use of Invega Sustenna 150 mg Injection 1.5 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Invega Sustenna 150 mg Injection 1.5 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PaliperidoneNilotinib
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
Combining Invega Sustenna 150 mg Injection 1.5 ml and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Invega Sustenna 150 mg Injection 1.5 ml and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PaliperidoneAmiodarone
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
Coadministration of Amiodarone with Invega Sustenna 150 mg Injection 1.5 ml can lead to or increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with Invega Sustenna 150 mg Injection 1.5 ml together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PaliperidoneBupropion
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
Bupropion is capable of causing seizures (fits), and combining it with Invega Sustenna 150 mg Injection 1.5 ml, may enhance the risk.

How to manage the interaction:
Co-administration of bupropion along with Invega Sustenna 150 mg Injection 1.5 ml can lead to an interaction, it can be taken if advised by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
PaliperidoneHydroxychloroquine
Severe
How does the drug interact with Invega Sustenna 150 mg Injection 1.5 ml:
The combined use of Invega Sustenna 150 mg Injection 1.5 ml and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Invega Sustenna 150 mg Injection 1.5 ml and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Invega Sustenna 150 mg Injection is used to treat Schizophrenia.
Invega Sustenna 150 mg Injection works by balancing the chemical messengers called neurotransmitters and blocking the effect of dopamine and serotonin located in the brain, thereby helping in improving mood, behaviour and thoughts.
Invega Sustenna 150 mg Injection may cause metabolic changes: So it is recommended to monitor for hyperglycemia/diabetes mellitus, dyslipidemia and weight gain. If you experience any major changes inform the doctor immediately.
Invega Sustenna 150 mg Injection may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Invega Sustenna 150 mg Injection . Diabetes patients should discuss with a doctor before taking Invega Sustenna 150 mg Injection .
Yes, orthostatic hypotension could be a side-effect of Invega Sustenna 150 mg Injection . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Invega Sustenna 150 mg Injection are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.
Invega Sustenna 150 mg Injection may make you sweat less, making you more likely to get heatstroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly.
Dry mouth could be a side-effect of Invega Sustenna 150 mg Injection . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Invega Sustenna 150 mg Injection is known to cause increased mortality in people who are elderly with dementia. So, please inform your doctor if you have dementia; before starting Invega Sustenna 150 mg Injection .
The side effects of Invega Sustenna 150 mg Injection include injection site reactions, dizziness, sleepiness or drowsiness, uncontrolled involuntary movements, abnormal muscle movements including tremor, restlessness and abnormal movements of eyes. If these side effects persist or worsen, please consult your doctor.
No, Invega Sustenna 150 mg Injection is not a narcotic.
Yes, Invega Sustenna 150 mg Injection is an atypical antipsychotic.
Yes, Invega Sustenna 150 mg Injection may cause weight gain. Therefore, follow a healthy diet to maintain proper weight during treatment with Invega Sustenna 150 mg Injection . If you have any concerns regarding this, discuss with your doctor.
Invega Sustenna 150 mg Injection may cause priapism (prolonged and/or painful erection), which may lead to erectile dysfunction. Therefore, you are advised to follow your doctor’s instructions regarding its use.
Invega Sustenna 150 mg Injection may stay in our system/body for around 4 to 8 months.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - INV0023

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