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Irinotraz 100Mg Inj is used to manage or treat Colorectal cancer (Cancer that develops in the colon or rectal tissue). It contains Irinotecan, which works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells cannot divide. As a result, Irinotecan inhibits cancer cell division and growth.
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About Irinotraz 100Mg Inj
Irinotraz 100Mg Inj belongs to a class of antineoplastic medications or chemotherapy drugs primarily used to manage or treat Colorectal cancer (Cancer that develops in the colon or rectal tissue). Colorectal cancer is a disease in which cells in the colon or rectum grow out of control.
Irinotraz 100Mg Inj contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can not divide. As a result, Irinotecan inhibits cancer cell division and growth.
Irinotraz 100Mg Inj should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. The most common adverse reactions are nausea, vomiting, abdominal pain, diarrhoea, constipation, anorexia (an eating disorder), Neutropenia (an unusually low number of cells called neutrophils), leukopenia (including lymphocytopenia), anaemia (not having enough healthy red blood cells), asthenia (abnormal weakness), fever, weight loss, alopecia (hair loss). You should talk to your doctor if you persistently experience these side effects.
Avoid using Irinotraz 100Mg Inj if you are allergic to it. Irinotraz 100Mg Inj can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on treatment with Irinotraz 100Mg Inj. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.
Uses of Irinotraz 100Mg Inj
Irinotraz 100Mg Inj is used to treat cancers of the colon and rectum. The detailed uses of Irinotraz 100Mg Inj are as follows:

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Medicinal Benefits
Irinotraz 100Mg Inj is an antineoplastic medicine or chemotherapeutic treatment used to control or treat colorectal cancer (colon or rectal cancer). Irinotraz 100Mg Inj contains Irinotecan acts by inhibiting an enzyme known as topoisomerase I. This enzyme is required for all cells to divide and flourish. Irinotecan inhibits this enzyme, preventing cancer cells from dividing. As a result, Irinotecan inhibits cancer cell division and growth.
How Irinotraz 100Mg Inj Works
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What if I have taken an overdose of Irinotraz 100Mg Inj
Drug Warnings
Before taking the Irinotraz 100Mg Inj, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may also suffer severe diarrhoea (known as ''late diarrhoea'') more than 24 hours after receiving Irinotecan. Your doctor would advise you to take antidiarrheal drugs at regular intervals throughout the day and night. When taking antidiarrheal drugs, always follow your doctor's instructions. During your therapy, your doctor will also inform you which foods to take and which to avoid to reduce diarrhoea. Drink plenty of fluids and strictly adhere to this diet.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Caution
Avoid alcohol consumption while on treatment with Irinotraz 100Mg Inj.
Pregnancy
Unsafe
Irinotraz 100Mg Inj should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.
Breast Feeding
Unsafe
Irinotraz 100Mg Inj should not be used in breastfeeding. Discuss with your doctor if you have any concerns.
Driving
Caution
Irinotraz 100Mg Inj can make you dizzy or impair your vision, especially in the first 24 hours after taking it. Do not drive or operate machinery until you know how this drug affects you.
Liver
Caution
Irinotraz 100Mg Inj should be used with caution if you have liver disease. Inform your doctor before receiving the Irinotraz 100Mg Inj if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Caution
It is not recommended for use in patients on dialysis. Inform your doctor before receiving the Irinotraz 100Mg Inj if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Caution
Safety and effectiveness in children have not been established. Hence, use is not recommended.
Heart
Irinotraz 100Mg Inj may be used in patients with heart problems, but it requires close monitoring due to risks like bradycardia and dehydration-related cardiac complications. Medical supervision is essential to ensure safe administration.
Geriatrics
Caution
Geriatric patients can receive irinotecan injections, but they may be more prone to severe side effects like diarrhea. Dose adjustments and close medical supervision are often necessary to ensure safe treatment.
Irinotraz 100Mg Inj is used to treat Colorectal cancer.
Irinotraz 100Mg Inj contains Irinotecan works by blocking an enzyme called topoisomerase I. All cells need this enzyme to divide and grow. Irinotecan blocks this enzyme so the cancer cells can't divide. As a result, Irinotecan inhibits cancer cell division and growth.
Irinotraz 100Mg Inj should not be used in patients with pulmonary diseases. So, inform your doctor if you have pulmonary disorders (lung problems).
While taking Irinotraz 100Mg Inj, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Irinotraz 100Mg Inj.
The live vaccine may not work while on treatment with Irinotraz 100Mg Inj. Only have immunizations/vaccinations after talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Irinotecan therapy may lead to Neutropenia (an unusually low number of neutrophil cells). Your doctor will order laboratory testing on a regular basis before and during your treatment.
You should know that this medicine may reduce fertility in both men and women. Discuss the risks of taking an irinotecan injection with your doctor.
You are recommended to take the advice of your doctor before taking Irinotraz 100Mg Inj. As Irinotraz 100Mg Inj is not used during pregnancy.
The common side effects of Irinotraz 100Mg Inj are nausea, vomiting, abdominal pain, diarrhoea, constipation, anorexia (an eating disorder), neutropenia (an unusually low number of cells called neutrophils), leukopenia (including lymphocytopenia), anaemia (not having enough healthy red blood cells), asthenia (abnormal weakness), fever, weight loss, alopecia (hair loss). If any of these side effects persist or worsen, please consult your doctor.
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