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  3. Isordil 5 Sublingual Tablet 10's

Isordil 5 Sublingual Tablet 10's, Pack of 10 TABLETS
Isordil 5 Sublingual Tablet 10's, Pack of 10 TABLETS
Isordil 5 Sublingual Tablet 10's, Pack of 10 TABLETS
Isordil 5 Sublingual Tablet 10's, Pack of 10 TABLETS
Isordil 5 Sublingual Tablet 10's, Pack of 10 TABLETS
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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy

Isordil 5 Sublingual Tablet is used in the prevention of angina (heart-related chest pain) and heart failure. It contains Isosorbide dinitrate, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. It may cause common side effects such as headache, light-headedness, weakness, nausea, vomiting, and dizziness. Let your doctor know if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ISOSORBIDE DINITRATE-5MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

SUBLINGUAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Isordil 5 Sublingual Tablet

Isordil 5 Sublingual Tablet belongs to the class of medications called ‘nitrate vasodilators’ used in the prevention of angina (heart-related chest pain) and heart failure. Angina pectoris (angina) is chest pain occurring due to reduced blood flow to the heart (coronary artery disease). It occurs when the blood vessels supplying blood to the heart are blocked or narrowed.

Isordil 5 Sublingual Tablet contains ‘isosorbide dinitrate’, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke, especially in high blood pressure patients.

Take Isordil 5 Sublingual Tablet as prescribed. Your doctor will advise you on how often you need to take Isordil 5 Sublingual Tablet based on your medical condition. The common side effects of Isordil 5 Sublingual Tablet are headache, light-headedness, weakness, nausea, vomiting, and dizziness. These side effects usually resolve without requiring medical attention. However, consult your doctor if any of these effects persist or worsen.

Do not take Isordil 5 Sublingual Tablet if you are allergic to any of its ingredients. Inform your doctor if you are taking other prescription or non-prescription medicines, especially medicines used to treat erectile dysfunction in men. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of Isordil 5 Sublingual Tablet in children have not been established.

Uses of Isordil 5 Sublingual Tablet

Isordil 5 Sublingual Tablet is used for the prevention of angina (heart-related chest pain) and heart failure. The detailed uses of Isordil 5 Sublingual Tablet are as follows:

  • Angina pectoris treatment:Isordil 5 Sublingual Tablet helps to relieve angina pectoris symptoms by widening blood vessels and improving blood flow to the heart, reducing chest pain.
  • Prevention of angina attacks:Isordil 5 Sublingual Tablet can be administered to prevent the occurrence of angina attacks, especially during physical activity or stressful situations.
  • Management of heart failure:Isordil 5 Sublingual Tablet helps to manage heart failure symptoms by reducing the heart's workload and improving blood flow, often used alongside other medications for better heart function.
  • Vasodilation:Isordil 5 Sublingual Tablet works by causing vasodilation, widening blood vessels, which reduces blood pressure and decreases the heart's workload, providing relief.
  • Post-myocardial infarction care:Isordil 5 Sublingual Tablet helps to improve oxygen supply to the heart and reduces cardiac workload in post-heart attack patients, supporting recovery and potentially lowering the risk of future heart issues.

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Directions for Use

  • Isordil 5 Sublingual Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Place Isordil 5 Sublingual Tablet below the tongue and allow it to dissolve.
  • Do not swallow Isordil 5 Sublingual Tablet as a whole directly. It is also advised not to chew or crush Isordil 5 Sublingual Tablet .

Medicinal Benefits

Isordil 5 Sublingual Tablet belongs to the class of medications called ‘nitrate vasodilators’ used in the prevention of angina (heart-related chest pain) and heart failure. It contains ‘isosorbide dinitrate’, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke, especially in high blood pressure patients.

How Isordil 5 Sublingual Tablet Works

Isordil 5 Sublingual Tablet contains isosorbide dinitrate, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke, especially in high blood pressure patients.

Storage

• Store in a cool and dry place away from sunlight.• Keep Isordil 5 Sublingual Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Isordil 5 Sublingual Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Isordil 5 Sublingual Tablet

Do not take more than the prescribed dose of Isordil 5 Sublingual Tablet as it may cause an overdose. The symptoms of overdose include fever, confusion, severe throbbing headache, fast heartbeats, severe dizziness, nausea, vomiting, stomach pain, vision problems, bloody diarrhoea, sweating, trouble breathing, fainting, cold or clammy skin, and seizures (fits). If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Isordil 5 Sublingual Tablet if you are allergic to ‘isosorbide dinitrate’ or any of its contents. Inform the doctor if you have severe low blood pressure, bleeding or increased pressure in the brain, severe dehydration, heart valve problems, inflammation of the heart wall, high blood pressure due to long-term lung disease, severe anaemia, glaucoma (increased pressure in the eye), glucose 6 phosphate dehydrogenase deficiency (a type of anemia), underactive thyroid (hypothyroidism), kidney or liver problems, head injury, hypothermia (low body temperature), or intolerance to some sugars. Consult your doctor if you are pregnant or breastfeeding. Isordil 5 Sublingual Tablet is not recommended for children as safety and effective have not been established.

Drug-Drug Interactions

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Isosorbide dinitrateSildenafil
Critical
Isosorbide dinitrateTadalafil
Critical

Drug-Drug Interactions

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Isosorbide dinitrateSildenafil
Critical
How does the drug interact with Isordil 5 Sublingual Tablet:
Coadministration of Isordil 5 Sublingual Tablet and Sildenafil can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isordil 5 Sublingual Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Isosorbide dinitrateTadalafil
Critical
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Tadalafil with Isordil 5 Sublingual Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isordil 5 Sublingual Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateAvanafil
Critical
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Avanafil with Isordil 5 Sublingual Tablet can cause low blood pressure.

How to manage the interaction:
Taking Isordil 5 Sublingual Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateRiociguat
Critical
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Riociguat with Isordil 5 Sublingual Tablet may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isordil 5 Sublingual Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateRopivacaine
Severe
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Isordil 5 Sublingual Tablet with ropivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil 5 Sublingual Tablet and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateChloroprocaine
Severe
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Isordil 5 Sublingual Tablet with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil 5 Sublingual Tablet and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateCabergoline
Severe
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Isordil 5 Sublingual Tablet with cabergoline can increase the effects of Cabergoline.

How to manage the interaction:
Although taking Isordil 5 Sublingual Tablet and cabergoline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateLidocaine
Severe
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Isordil 5 Sublingual Tablet with lidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil 5 Sublingual Tablet and lidocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateBupivacaine
Severe
How does the drug interact with Isordil 5 Sublingual Tablet:
Combining Bupivacaine with Isordil 5 Sublingual Tablet can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bupivacaine with Isordil 5 Sublingual Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.
Isosorbide dinitrateLevobupivacaine
Severe
How does the drug interact with Isordil 5 Sublingual Tablet:
Taking Isordil 5 Sublingual Tablet with levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isordil 5 Sublingual Tablet and levobupivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat plenty of fresh fruits and vegetables.
  • Choose whole grains rather than refined or polished grains, lean proteins, such as skinless chicken and fish, and non-fat or low-fat dairy products.
  • Do not take food containing high levels of sodium (salt).
  • Drink plenty of fluids to prevent dehydration.
  • Maintain a normal weight. Shed excess weight by exercising regularly for at least 30 minutes a day.
  • Manage stress with yoga or meditation.
  • Limit alcohol intake and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Isordil 5 Sublingual Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side effects. So, do not consume alcohol.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if isosorbide dinitrate passes into breastmilk. Please consult your doctor before taking Isordil 5 Sublingual Tablet if you are a breastfeeding mother.

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Driving

Caution

Isordil 5 Sublingual Tablet may cause dizziness and affect your ability to drive. So, avoid driving or operating heavy machinery while using Isordil 5 Sublingual Tablet unless you are alert.

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Liver

Caution

Inform your doctor if you have liver impairment. Your doctor will weigh the benefits and any potential risks before prescribing.

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Kidney

Caution

Inform your doctor if you have kidney impairment. Your doctor will weigh the benefits and any potential risks before prescribing.

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Children

Caution

Isordil 5 Sublingual Tablet should not be given to children as safety and effectiveness were not established.

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Heart

Isordil 5 Sublingual Tablet is used with caution in cardiac patients and regular monitoring is required.

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Geriatrics

Safe if prescribed

Isordil 5 Sublingual Tablet is safe for elderly patients if used as prescribed and dose adjustment is required.

FAQs

Isordil 5 Sublingual Tablet is used to prevent angina (heart-related chest pain) and heart failure.

Isordil 5 Sublingual Tablet works by relaxing the muscles of the blood vessels. It helps to dilate the narrowed blood vessels, resulting in increased blood and oxygen supply to the heart. This prevents heart-related chest pain known as angina.

Isordil 5 Sublingual Tablet may decrease blood pressure (hypotension). Therefore, let the doctor know if you have high/low blood pressure or if you are taking blood pressure medications.

Use of Isordil 5 Sublingual Tablet together with sildenafil is not recommended as it may cause a sudden decrease in blood pressure. Therefore, consult a doctor before taking sildenafil during treatment with Isordil 5 Sublingual Tablet .

Isordil 5 Sublingual Tablet is given for heart-related chest pain (angina), a life-long or chronic disease, especially in high blood pressure patients and coronary heart disease (CAD). So, do not stop taking Isordil 5 Sublingual Tablet even if you feel better. Consult your doctor if you have any concerns.

The common side effects of Isordil 5 Sublingual Tablet are headache, light-headedness, weakness, nausea, vomiting, and dizziness. These side effects usually resolve without requiring medical attention. However, consult your doctor if any of these effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - ISO0013

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Reference

  1. https://pdf.hres.ca/dpd_pm/00080707.PDF
  2. https://www.nps.org.au/assets/medicines/ae9b36bf-1167-4712-a2df-a53300fea508-reduced.pdf
  3. https://labeling.pfizer.com/ShowLabeling.aspx?id=12816

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