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compositionComposition:ITRACONAZOLE-100MG
prescription
Prescription Medicine
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Itrasan-100 Tablet is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ITRACONAZOLE-100MG

Manufacturer/Marketer :

Sansis Biopharmacy Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Itrasan-100 Tablet

Itrasan-100 Tablet is an antifungal medicine used to treat a wide variety of fungal infections. It is commonly prescribed for infections affecting the nails, skin, mouth, throat, or lungs. By stopping the growth of fungi, this medicine helps clear the infection and prevents it from spreading.

To get the best results, you must take Itrasan-100 Tablet consistently at the same times every day as directed by your healthcare provider. If you are taking the capsule form, it is highly recommended to take it with a full meal to ensure your body absorbs the medication properly. Keeping your skin clean and dry and wearing breathable cotton clothing can also support your recovery.

While taking Itrasan-100 Tablet , some people may experience mild side effects like an upset stomach, nausea, or headaches. However, you must contact your doctor immediately if you experience signs of liver damage, such as yellowing of the skin or eyes, dark urine, or severe fatigue.

Talk to your doctor before starting this medicine if you have a history of heart problems, liver disease, or kidney issues. Do not take this if you have heart failure or a history of congestive heart failure, as this medication can make these conditions worse.

Itrasan-100 Tablet can interact with several other medications, including certain blood thinners, cholesterol-lowering drugs, and acid reducers, which can lower its effectiveness. Avoid drinking alcohol while taking this medicine, as it can increase the risk of liver damage. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before using this medicine.

Uses of Itrasan-100 Tablet

Your doctor may prescribe Itrasan-100 Tablet to treat several conditions, including:

  • Fungal nail infections (onychomycosis): Itrasan-100 Tablet helps clear fungal infections in both toenails and fingernails, allowing healthy, normal nails to grow back over time.
  • Ringworm and athlete's foot (tinea infections): It treats stubborn skin infections by stopping the spread of the fungus on the surface of the skin, relieving itching and scaling.
  • Thrush (oral candidiasis): It clears yeast infections in the mouth and throat, reducing pain and making swallowing comfortable again.
  • Systemic fungal infections: It treats deeper, more serious fungal infections that can affect internal organs like the lungs, helping your body fight off the infection.

Key Benefits

Itrasan-100 Tablet offers reliable relief from the uncomfortable symptoms of fungal infections, helping you return to your normal daily routine.

  • Targeted clearance: It works directly at the site of the infection, whether deep in the nail bed or on the skin surface.
  • Convenient oral routine: Being an oral medication, it treats widespread or deep-seated infections that topical creams cannot reach.
  • Long-lasting protection: The medicine remains in your skin and nail tissues for some time even after you finish the course, helping prevent the infection from returning.
Side effects of Itrasan-100 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.

Directions for Use

Itrasan-100 Tablet offers reliable relief from the uncomfortable symptoms of fungal infections, helping you return to your normal daily routine.

  • Targeted clearance: It works directly at the site of the infection, whether deep in the nail bed or on the skin surface.
  • Convenient oral routine: Being an oral medication, it treats widespread or deep-seated infections that topical creams cannot reach.
  • Long-lasting protection: The medicine remains in your skin and nail tissues for some time even after you finish the course, helping prevent the infection from returning.

How Itrasan-100 Tablet Works

Itrasan-100 Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of the cell membranes of fungi). This weakens and damages the fungal cell membranes that are essential for their survival, as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.
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Alcohol

Unsafe

Avoid consumption of alcohol with Itrasan-100 Tablet as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Itrasan-100 Tablet is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Itrasan-100 Tablet .

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Breast Feeding

Consult your doctor

Itrasan-100 Tablet is excreted in human milk and may harm the baby. Therefore, Itrasan-100 Tablet is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Unsafe

Itrasan-100 Tablet may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Itrasan-100 Tablet .

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Liver

Caution

Take Itrasan-100 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Itrasan-100 Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Itrasan-100 Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

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Heart

Unsafe

Itrasan-100 Tablet is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Caution

Elderly patients taking Itrasan-100 Tablet should maintain caution during the treatment, as it is known to cause side effects like hearing loss or age-related problems.

What if I have taken an overdose of Itrasan-100 Tablet

If you take too much of this medication, seek immediate medical attention or call a poison control center right away.

Diet & Lifestyle Advise

  • Take with acidic drinks if needed: If you take stomach acid reducers, taking Itrasan-100 Tablet capsules with an acidic drink like cola can help your body absorb the medicine better.
  • Keep infected areas dry: Fungi thrive in warm, moist environments. Dry your skin thoroughly after showering, especially between your toes and in skin folds.
  • Wear breathable clothing: Choose loose-fitting cotton clothing and breathable leather or canvas shoes to reduce moisture buildup.
  • Avoid sharing personal items: Do not share towels, nail clippers, socks, or footwear with others to prevent spreading or re-infecting yourself.
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How Soon It Starts Working

  • The time required for Itrasan-100 Tablet to start to work: Itrasan-100 Tablet ideally shows its action within 5 hours after administration.
  • The time for which the effects of Itrasan-100 Tablet last: The effect of Itrasan-100 Tablet lasts for 16 to 28 hours.

What if you forget to take Itrasan-100 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Itrasan-100 Tablet at room temperature, ideally between 15°C and 25°C (59°F to 77°F). • Keep the medication in its original container, tightly closed, to protect it from light and direct moisture.

Drug Warnings

  • Monitor your liver: Your doctor may require regular blood tests to check your liver function while you are taking this medicine.
  • Check the oral liquid: If you are using the liquid form, inspect the solution before use; it should be clear and free of particles.
  • Watch for heart failure signs: Stop taking the medication and seek emergency care if you develop unexpected shortness of breath or swelling in your ankles.
  • Limit acid reducers: Avoid taking antacids within 2 hours of taking Itrasan-100 Tablet capsules, as they can prevent the medicine from being absorbed properly.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Acid reducers (antacids, PPIs): May lower the absorption of Itrasan-100 Tablet , making it less effective.
  • Statins (cholesterol-lowering drugs): Itrasan-100 Tablet can increase the levels of these drugs in your blood, increasing the risk of muscle damage.
  • Blood thinners: Taking Itrasan-100 Tablet with certain blood thinners can increase the risk of bleeding.
  • Heart rhythm medications: Combining these can lead to serious, life-threatening heart rhythm issues.
ItraconazoleErgotamine
Critical
ItraconazoleEplerenone
Critical

Drug-Drug Interactions

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ItraconazoleErgotamine
Critical
How does the drug interact with Itrasan-100 Tablet:
The blood levels and effects of ergotamine may be greatly increased when combined with Itrasan-100 Tablet.

How to manage the interaction:
Ergotamine and Itrasan-100 Tablet may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.
ItraconazoleEplerenone
Critical
How does the drug interact with Itrasan-100 Tablet:
The blood levels and effects of eplerenone may be greatly increased when combined with Itrasan-100 Tablet.

How to manage the interaction:
Although there is a possible interaction between Eplerenone and Itrasan-100 Tablet, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
ItraconazoleTriazolam
Critical
How does the drug interact with Itrasan-100 Tablet:
Co-administration of Triazolam and Itrasan-100 Tablet may significantly increase the levels of Triazolam.

How to manage the interaction:
Although combining Triazolam and Itrasan-100 Tablet may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleAlprazolam
Critical
How does the drug interact with Itrasan-100 Tablet:
Alprazolam's blood levels may be significantly raised when combined with Itrasan-100 Tablet.

How to manage the interaction:
Although combining Alprazolam and Itrasan-100 Tablet may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleTolvaptan
Critical
How does the drug interact with Itrasan-100 Tablet:
Co-administration of Tolvaptan and Itrasan-100 Tablet may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Itrasan-100 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleNisoldipine
Critical
How does the drug interact with Itrasan-100 Tablet:
The blood levels and effects of nisoldipine may be greatly increased when used with Itrasan-100 Tablet.

How to manage the interaction:
Nisoldipine and Itrasan-100 Tablet may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleColchicine
Critical
How does the drug interact with Itrasan-100 Tablet:
Coadministration of colchicine with Itrasan-100 Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Itrasan-100 Tablet can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ItraconazoleSilodosin
Critical
How does the drug interact with Itrasan-100 Tablet:
Coadministration of Itrasan-100 Tablet with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Itrasan-100 Tablet with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
ItraconazoleCisapride
Critical
How does the drug interact with Itrasan-100 Tablet:
The blood level of Cisapride may be significantly raised by combining Cisapride with Itrasan-100 Tablet.

How to manage the interaction:
Despite the possibility of an interaction when cisapride and Itrasan-100 Tablet are combined, they can be taken if a doctor prescribes them. Consult a doctor if you develop any side symptoms, such as fainting, lightheadedness, dizziness, or rapid or pounding heartbeats. Without consulting a doctor, never stop taking any medication. Note: Cisapride is no longer available in the market.
ItraconazoleIsavuconazole
Critical
How does the drug interact with Itrasan-100 Tablet:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Itrasan-100 Tablet along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Itrasan-100 Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: Avoid drinking grapefruit juice, as it can interfere with how your body processes Itrasan-100 Tablet and increase the risk of side effects.
  • Full meals: Itrasan-100 Tablet capsules require food in the stomach to be properly absorbed, whereas the oral solution should not be taken with food.
ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Itrasan-100 Tablet may impair the absorption of Itrasan-100 Tablet, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Itrasan-100 Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Itrasan-100 Tablet is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.
You are not recommended to take Itrasan-100 Tablet with simvastatin, as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark-coloured urine, fever, or flu-like symptoms. However, please consult a doctor before using Itrasan-100 Tablet with other medicines.
Itrasan-100 Tablet may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itrasan-100 Tablet to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itrasan-100 Tablet and consult a doctor immediately.
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are not recommended to stop taking Itrasan-100 Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Itrasan-100 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itrasan-100 Tablet , please consult your doctor.
Inform your doctor if you are sexually active and discuss effective contraception methods. Itrasan-100 Tablet may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Itrasan-100 Tablet .
Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Itrasan-100 Tablet may interact with other medicines. Also, let your doctor know if you are stopping any medicine.
Itrasan-100 Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.
Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.
The side effects of Itrasan-100 Tablet include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.
If you have taken overdose of Itrasan-100 Tablet , please consult your doctor immediately.
Store Itrasan-100 Tablet at room temperature. Protect from light and moisture. Keep out of reach and sight of children.
It is best to avoid alcohol while taking Itrasan-100 Tablet . Both alcohol and this medicine are processed by the liver, and combining them can increase your risk of liver damage. Talk to your doctor if you have concerns.
Nail infections take time to clear because the healthy nail must grow out. While the medicine starts working immediately to stop the fungus, you may not see the full results until several months after completing your treatment. Talk to your doctor if you do not notice improvement.
No, Itrasan-100 Tablet is generally not recommended during pregnancy as it can harm an unborn baby. You should use effective birth control while taking this medicine and for several weeks after stopping it. Talk to your doctor for safer alternatives.
Yes, if you are taking the capsule form, you should take it with a full meal to help your body absorb it. If you are taking the oral solution, it should be taken on an empty stomach. Talk to your doctor or pharmacist to confirm which form you have.
Mild stomach upset or nausea is common when first starting this medicine. Taking the capsule form with a meal can help reduce these side effects. If your stomach issues are severe or do not go away, talk to your doctor.
Antacids and other acid reducers can stop your body from absorbing Itrasan-100 Tablet capsules. You should take antacids at least 2 hours after taking this medicine, or take the capsules with an acidic beverage like cola. Talk to your pharmacist for specific advice.
Watch for warning signs of liver damage, including yellowing of your skin or eyes, unusually dark urine, pale stools, severe nausea, vomiting, or extreme fatigue. If you notice any of these symptoms, stop taking the medicine and call your doctor right away.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 022484S000Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. MIMS Drug Reference Compendium. Itraconazole+ +oral Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Itraconazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Itraconazole Itraconazole. 1992. [Accessed on 29 Mar. 2019]Check here
  5. Kurn H, Wadhwa R Itraconazole. [Updated 2023 Apr 17]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Check here
  6. Janssen Pharmaceutical. SPORANOX® (itraconazole) Capsules: Prescribing Information [Internet]. Titusville (NJ): Janssen Pharmaceutical; [Accessed on 2025 Sep 16]Check here
  7. Thame Laboratories. Itraconazole 10 mg/ml Oral Solution: Summary of Product Characteristics [Internet]. High Wycombe: electronic Medicines Compendium (emc); [Accessed on 2025 Sep 16]Check here

Country of origin

India

Manufacturer/Marketer address

House No- MIG-II-279 Phase-III Kalinga Vihar, PS - Chhend Rourkela, Sundargarh, Sundergarh-769015, Odisha, India
Other Info - ITR0237
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