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  3. Joseiz 100 Tablet

Joseiz 100 Tablet, Pack of 1 Tablet
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Joseiz 100 Tablet is used to treat focal (partial) seizures in adults and children four years of age or older. It contains Lacosamide, which treats seizures by decreasing disorganized electrical activity in the brain. In some cases, you may experience certain common side effects such as nausea, vomiting, diarrhoea, headache, confusion, dizziness, uncontrolled movements of the eye, blurred vision, double vision (diplopia), mood disturbances, itching, tremors, fatigue, and trouble walking. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

LACOSAMIDE-100MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Joseiz 100 Tablet

Joseiz 100 Tablet belongs to the class of anticonvulsants, which is primarily used to treat focal (partial) seizures in adults and children four years of age or older. Focal or partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere.

Joseiz 100 Tablet contains lacosamide, which treats seizures by decreasing disorganized electrical activity in the brain.

In some cases, you may experience certain common side effects of Joseiz 100 Tablet: nausea, vomiting, diarrhoea, headache, confusion, dizziness, uncontrolled movements of the eye, blurred vision, double vision (diplopia), mood disturbances, itching, tremors, fatigue, and trouble walking. Consult your doctor if the side effects persist or worsen over time. Some people may also experience suicidal thoughts. Seek medical attention immediately in such cases.

Do not stop taking Joseiz 100 Tablet even if your condition is controlled, as abrupt stopping may cause the recurrence of the seizures. Before taking Joseiz 100 Tablet, inform your doctor if you are allergic to lacosamide or other ingredients, if you are using other antiepileptics, prescription or non-prescription drugs, nutritional supplements, or herbal products or if you are diagnosed with depression, severe renal impairment, arrhythmias (atrioventricular block, atrial fibrillation, and atrial flutter), severe heart failure, or a heart attack.

Uses of Joseiz 100 Tablet

Treatment of Focal or partial seizures.

Directions for Use

  • Joseiz 100 Tablet can be taken with food to help reduce the risk of stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Joseiz 100 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Joseiz 100 Tablet is an antiepileptic drug, also called anticonvulsant. It treats focal seizures in adults and children above four years of age.  Joseiz 100 Tablet inactivates the sodium channels across the neuron membranes. This inactivation decreases neuron signals, thereby decreasing the electrical disturbance or abnormal activity in the brain.

How Joseiz 100 Tablet Works

Joseiz 100 Tablet contains lacosamide, which treats seizures by decreasing disorganized electrical activity in the brain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Joseiz 100 Tablet
  • Wear an eye patch or opaque contact lens or lens applied to glasses to block the vision of one eye to minimize double vision.
  • Use prisms (lenses applied to glasses) to correct double vision due to small misalignments.
  • Try doing some eye exercises such as moving the target towards nose slowly or focussing on a detailed target like thin stick or small text in a magazine.
  • If you feel eye pain, develop bulging eyes, have weakness, headache or double vision, consult a doctor immediately.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Joseiz 100 Tablet

Do not take more than the prescribed dose of Joseiz 100 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor if you use other antiepileptics, prescription or non-prescription drugs, nutritional supplements, or herbal products. Do not take Joseiz 100 Tablet if you are allergic to any of its contents. Inform your doctor before taking Joseiz 100 Tablet if you have or had heart problems, kidney and liver problems, if you have low levels of sodium in blood or if you are taking medicines that could lower the sodium levels in the blood, or if you are using hormonal contraceptives. Do not stop taking Joseiz 100 Tablet without consulting your doctor to avoid precipitating seizures. Avoid intake of Joseiz 100 Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor. Nursing mothers should consult the doctor before using the Joseiz 100 Tablet as it may pass into the breast milk and affect the baby. Joseiz 100 Tablet causes drowsiness and dizziness, so drive only if you are alert. Joseiz 100 Tablet should not be given to children unless prescribed. Avoid consuming alcohol with Joseiz 100 Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Drug-Drug Interactions

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LacosamideEsketamine
Severe
LacosamideCeritinib
Severe

Drug-Drug Interactions

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LacosamideEsketamine
Severe
How does the drug interact with Joseiz 100 Tablet:
When used with Joseiz 100 Tablet, Esketamine may increase the risk of side effects.

How to manage the interaction:
Although taking Joseiz 100 Tablet and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not discontinue any medications without a doctor's advice.
LacosamideCeritinib
Severe
How does the drug interact with Joseiz 100 Tablet:
Taking Ceritinib together with Joseiz 100 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Joseiz 100 Tablet and Ceritinib together can result in an interaction, it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty. Do not discontinue any medications without consulting a doctor.
LacosamideKetamine
Severe
How does the drug interact with Joseiz 100 Tablet:
When Ketamine and Joseiz 100 Tablet are combined, may increase the risk of side effects.

How to manage the interaction:
Although taking Joseiz 100 Tablet and Ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as dizziness, drowsiness, confusion, breathing difficulty, impairment in thinking, judgment, and motor coordination, consult the doctor. Do not discontinue any medications without a doctor's advice.
LacosamideDolasetron
Severe
How does the drug interact with Joseiz 100 Tablet:
Co-administration of Joseiz 100 Tablet and Dolasetron can increase the risk of serious irregularities in heart rhythm.

How to manage the interaction:
Although taking Joseiz 100 Tablet and Dolasetron together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, dizziness, fainting, or an irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
LacosamideSaquinavir
Severe
How does the drug interact with Joseiz 100 Tablet:
Co-administration of Joseiz 100 Tablet along with Saquinavir can raise the chance of an abnormal heart rhythm.

How to manage the interaction:
Although taking Joseiz 100 Tablet and Saquinavir together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, fainting, a slow heartbeat, or dizziness, consult a doctor. Do not discontinue any medications without a doctor's advice.
LacosamideSodium oxybate
Severe
How does the drug interact with Joseiz 100 Tablet:
Co-administration of Joseiz 100 Tablet with Sodium oxybate can increase side effects.

How to manage the interaction:
Although taking Joseiz 100 Tablet and Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience any symptoms such as drowsiness, dizziness, lightheadedness, confusion, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination. Do not discontinue any medications without a doctor's advice.
LacosamideBuprenorphine
Severe
How does the drug interact with Joseiz 100 Tablet:
When Buprenorphine is used with Joseiz 100 Tablet, it may lead to side effects such as respiratory difficulties, and unconsciousness.

How to manage the interaction:
Although the combination of Buprenorphine with Joseiz 100 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You are advised to avoid driving or operating hazardous machinery. Do not discontinue any medications without consulting a doctor.
LacosamideIdelalisib
Severe
How does the drug interact with Joseiz 100 Tablet:
When Joseiz 100 Tablet is taken along with Idelalisib, it might enhance the amount or action of Joseiz 100 Tablet, which may increase the risk of side effects.

How to manage the interaction:
Although taking Joseiz 100 Tablet and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Joseiz 100 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Consuming alcohol with Joseiz 100 Tablet is not advisable as it may cause unpleasant side effects.

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Pregnancy

Consult your doctor

Joseiz 100 Tablet should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Joseiz 100 Tablet.

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Breast Feeding

Consult your doctor

Joseiz 100 Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Joseiz 100 Tablet.

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Driving

Unsafe

Joseiz 100 Tablet may cause a reduction in mental awareness; thus, avoid operating machinery or driving.

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Liver

Consult your doctor

Tell your doctor before taking Joseiz 100 Tablet if you have a history of liver disease. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Consult your doctor

Tell your doctor before taking Joseiz 100 Tablet if you have a history of kidney disease. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Caution

It is used with caution in children above 4 years only when prescribed by a child specialist. It is not recommended for use in children below 4 years of age. The dose of this medicine will be decided by the doctor based on the age and body weight of your child.

Have a query?

FAQs

Joseiz 100 Tablet is used to treat focal (partial) seizures in adults and children four years of age or older.

Joseiz 100 Tablet contains lacosamide, which treats seizures by decreasing disorganized electrical activity in the brain.

Joseiz 100 Tablet can cause memory loss and cognitive impairment in some cases. Consult a doctor right away if the condition worsens.

Joseiz 100 Tablet may not cause any weight gain. However, consult your doctor if you notice any abnormal signs while using Joseiz 100 Tablet.

Joseiz 100 Tablet is typically recommended for long-term use. Keep taking the medication as advised by your doctor. However, if you have any unsettling side effects, speak to your doctor.

Joseiz 100 Tablet may usually one week or longer to work depending on your condition.

Joseiz 100 Tablet should also be taken with caution in patients who are taking drugs that influence cardiac conduction, such as sodium channel blockers, beta-blockers, calcium channel blockers, potassium channel blockers, and medications that lengthen the PR interval.

Joseiz 100 Tablet can be given as monotherapy or in combination with other antiepileptic drugs. However, you are recommended not to take any other medications with the Joseiz 100 Tablet on your own without a doctor's recommendation.

The side effects of Joseiz 100 Tablet include headache, double or blurred vision, nausea, dizziness, vertigo (spinning sensation), tremor, uncontrollable eye movements, tingling or muscle spasms. If these side effects persist or worsen, please consult your doctor.

No, do not stop taking Joseiz 100 Tablet even if you feel better. Discontinuing suddenly may worsen your condition and lead to uncontrollable seizures. Therefore, use Joseiz 100 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while using Joseiz 100 Tablet, please consult your doctor.

Do not drive or use any tools or machines until you know how Joseiz 100 Tablet affects you as it may cause dizziness or blurred vision.

If you missed a dose of Joseiz 100 Tablet, take it within first 6 hours of the scheduled dose. However, if you have forgotten a dose for more than the first 6 hours of the scheduled dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the forgotten one as this may increase the risk of side effects.

No, Joseiz 100 Tablet is not a habit-forming medicine.

There have been no reports of Joseiz 100 Tablet affecting fertility in either males or females. However, if you have any concerns, please consult a doctor.

Joseiz 100 Tablet is usually not recommended for use during pregnancy or breastfeeding. However, seek doctor’s advice if you are pregnant or breastfeeding.

Excess of Joseiz 100 Tablet may cause nausea, dizziness, vomiting, seizures, and even coma. If somebody takes excess of Joseiz 100 Tablet, seek medical help immediately.

Caution is advised if you are taking Joseiz 100 Tablet while on Ritonavir therapy. It is recommended that you inform your doctor before starting Joseiz 100 Tablet. This is because if you are taking Ritonavir for kidney or liver problems then the dose of Joseiz 100 Tablet needs to be adjusted or reduced.

Country of origin

India
Other Info - JO19070

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 11:29 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.2286.pdf
  2. https://www.telfordccg.nhs.uk/your-health/medicines-management/shared-care-agreements-prescribing-information-documents/central-nervous-system/central-nervous-system-prescribing-information-documents/2726-lacosamide-prescribing-information-mar-17/file#:~:text=Lacosamide%20(Vimpat%C2%AE)%20is%20indicated,18%20years)%20patients%20with%20epilepsy.&text=Lacosamide%20must%20be%20taken%20twice,and%20once%20in%20the%20evening).
  3. https://medlineplus.gov/druginfo/meds/a609028.html
  4. https://www.epilepsy.com/tools-resources/seizure-medication-list/lacosamide
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