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compositionComposition:OFLOXACIN-100MG
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Prescription Medicine
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Jox 100 mg Suspension is an antibiotic medicine used to treat bacterial infections in children. It contains Ofloxacin belonging to the fluoroquinolone class of drugs. It works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OFLOXACIN-100MG

Manufacturer/Marketer :

DR Johns Lab Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Jox 100 mg Suspension

Jox 100 mg Suspension is a prescription antibiotic containing ofloxacin. It may be used to treat certain bacterial infections in children when the doctor decides that ofloxacin is appropriate based on the type of infection, the bacteria involved, and other available treatments. It does not treat infections caused by viruses, such as the common cold or flu.

Ofloxacin belongs to a group of antibiotics called fluoroquinolones. These medicines are generally not a first choice for children because they can cause uncommon but important side effects involving the joints and tendons (strong tissues that connect muscles to bones). A doctor may prescribe ofloxacin when other suitable antibiotics cannot be used or when its expected benefit is considered greater than the potential risks.

Give Jox 100 mg Suspension exactly as prescribed for your child. The dose and length of treatment depend on factors such as your child's age, weight, kidney function, type of infection, and response to treatment. Use an appropriate measuring device for each dose and follow the prescribed treatment duration, even if your child starts to feel better.

Some children may experience nausea, stomach discomfort, loose stools, headache, or dizziness. Contact your child's doctor promptly if your child develops new joint or tendon pain, swelling, difficulty walking, severe or persistent diarrhoea, or other concerning symptoms. Seek urgent medical help for difficulty breathing or swelling of the face, lips, tongue, or throat, as these may be signs of a serious allergic reaction.

Before treatment, tell the doctor if your child has previously had an allergic reaction to ofloxacin or another fluoroquinolone antibiotic, or has kidney problems, seizures, or a history of tendon or joint problems. Also tell the doctor or pharmacist about all medicines, vitamins, antacids, and mineral supplements your child takes because some products can affect how ofloxacin works.

Uses of Jox 100 mg Suspension

Jox 100 mg Suspension may be prescribed for certain bacterial infections in children when the doctor determines that ofloxacin is an appropriate treatment. Its use depends on the type of infection, the bacteria involved, local antibiotic guidance, and whether suitable alternatives are available.

  • Complicated urinary tract infections: Jox 100 mg Suspension may be used for certain urinary tract infections caused by bacteria that are susceptible (sensitive) to ofloxacin, particularly when other suitable antibiotics are not appropriate.
  • Typhoid or enteric fever: In some settings, ofloxacin may be considered for enteric fever caused by susceptible Salmonella bacteria. Its use depends on local resistance patterns and current treatment guidance, as resistance to fluoroquinolone antibiotics is common in many regions.
  • Other susceptible bacterial infections: A doctor may consider Jox 100 mg Suspension for selected serious bacterial infections when testing or clinical assessment indicates that ofloxacin is suitable and other treatment options are limited.

Key Benefits

When ofloxacin is considered appropriate for your child, Jox 100 mg Suspension can help control a susceptible bacterial infection and support recovery.

  • Helps clear bacterial infection: Ofloxacin stops susceptible bacteria from multiplying and surviving, allowing the infection to gradually resolve.
  • Supports symptom improvement: As the infection responds to treatment, symptoms such as fever, discomfort, reduced appetite, or low energy may improve. The response and time to improvement depend on the type and severity of infection.
  • Easy administration: The suspension can make it easier to give the prescribed dose to children who have difficulty swallowing tablets.
Side effects of Jox 100 mg Suspension 60 ml

Directions for Use

  • Jox 100 mg Suspension can be administered with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Measure the recommended dose of Jox 100 mg Suspension with the help of a measuring cup, dosing syringe or dropper and administer it to your child.
  • Shake well before use.

How Jox 100 mg Suspension Works

Jox 100 mg Suspension contains ofloxacin, an antibiotic that works against susceptible bacteria. It stops bacteria from copying and repairing their genetic material (DNA), which they need to grow and survive. Ofloxacin blocks two bacterial enzymes called DNA gyrase and topoisomerase IV. These enzymes help bacteria manage their DNA during growth and multiplication. When both enzymes are blocked, the bacteria can no longer copy their DNA properly, which stops their growth and leads to their death. As the susceptible bacteria are cleared, the infection can gradually improve. Jox 100 mg Suspension works only against bacterial infections and does not treat viral infections such as colds or flu.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.

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Children

Safe if prescribed

Jox 100 mg Suspension is safe for children if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

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Heart

Caution

Jox 100 mg Suspension may rarely cause a serious heart rhythm issue (QT prolongation and torsades de pointes). Children with heart conditions or on certain medications may be at higher risk. Consult a pediatrician before use.

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Geriatrics

Not applicable

Jox 100 mg Suspension is for paediatric patients only.

What if I have taken an overdose of Jox 100 mg Suspension

If your child receives more Jox 100 mg Suspension than prescribed, contact a doctor or seek urgent medical advice, even if your child seems well. Keep the medicine bottle or packaging with you so the healthcare team can check what medicine and amount may have been taken.

Diet & Lifestyle Advise

  • Keep your child hydrated: Encourage enough fluids, particularly if your child has diarrhoea, vomiting, or fever, to help prevent dehydration.
  • Choose comfortable foods if needed: If your child has nausea or stomach discomfort, smaller, simple meals may be easier to tolerate.
  • Check before giving mineral products: Antacids or supplements containing aluminium, magnesium, iron, or zinc can reduce how much ofloxacin the body absorbs. Ask your doctor or pharmacist how to space these products from Jox 100 mg Suspension.
  • Follow individual advice about dairy: Milk, yoghurt, cheese, and other dairy foods do not usually need to be completely avoided during treatment. Ask your doctor or pharmacist if your child's specific product has instructions about taking it with dairy or calcium-fortified foods.
  • Protect your child's skin from strong sunlight: Ofloxacin may make the skin more sensitive to sunlight in some children. Consider protective clothing and suitable sun protection when outdoors.
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How Soon It Starts Working

The time required for Jox 100 mg Suspension to start to work: Jox 100 mg Suspension ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Jox 100 mg Suspension last: The effect of Jox 100 mg Suspension lasts for 2 days.

What if you forget to take Jox 100 mg Suspension

If you forget to give your child a dose of Jox 100 mg Suspension, give it when you remember unless it is nearly time for the next dose. In that case, skip the missed dose and continue with the usual schedule. Do not give two doses at the same time to make up for a missed dose. If you are unsure what to do, ask your child's doctor or pharmacist.

Storage

• Store the bottle of Jox 100 mg Suspension according to the instructions on the product label, typically between 20°C and 25°C.

Drug Warnings

  • Measure each dose carefully: Use the oral syringe, measuring spoon, or cup supplied or recommended by your pharmacist rather than a household spoon.
  • Follow the prescribed course: Continue giving Jox 100 mg Suspension for the duration prescribed by your child's doctor, even if your child starts to feel better. Speak with the doctor before making changes to the treatment.
  • Watch for joint or tendon symptoms: Contact your child's doctor promptly if your child develops new joint or tendon pain, swelling, tenderness, or difficulty walking. The doctor can advise whether treatment needs to be changed.
  • Look out for severe diarrhoea: Seek medical advice promptly if your child develops severe, persistent, watery, or bloody diarrhoea during treatment or after it has finished.
  • Mention other medicines: Tell your child's doctor or pharmacist about any medicines, antacids, vitamins, or mineral supplements your child takes, as some may interact with ofloxacin.

Drug-Drug Interactions

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  • Antacids: Products containing aluminium or magnesium can reduce the amount of ofloxacin absorbed by the body. Ask your doctor or pharmacist how to space them from Jox 100 mg Suspension.
  • Iron or zinc supplements: These minerals can reduce the absorption of ofloxacin when taken around the same time. Your doctor or pharmacist can advise how much time to leave between doses.
  • Certain medicines that affect heart rhythm: Taking ofloxacin with some medicines that also affect the heart's rhythm may increase the risk of an abnormal heartbeat. Make sure your child's doctor knows about all medicines your child takes.
  • Certain medicines that affect the brain or nervous system: Some medicines may increase the risk of nervous-system side effects when taken with ofloxacin. Your child's doctor can check whether any medicines need additional monitoring.

Drug-Drug Interactions

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How does the drug interact with Jox 100 mg Suspension 60 ml:
Coadministration of Jox 100 mg Suspension 60 ml with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jox 100 mg Suspension 60 ml:
Coadministration of Jox 100 mg Suspension 60 ml with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
OfloxacinQuinidine
Critical
How does the drug interact with Jox 100 mg Suspension 60 ml:
Coadministration of Jox 100 mg Suspension 60 ml with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Jox 100 mg Suspension 60 ml:
Using halofantrine together with Jox 100 mg Suspension 60 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Jox 100 mg Suspension 60 ml:
Coadministration of Jox 100 mg Suspension 60 ml with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Jox 100 mg Suspension 60 ml:
Using bepridil together with Jox 100 mg Suspension 60 ml drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
How does the drug interact with Jox 100 mg Suspension 60 ml:
Coadministration of Jox 100 mg Suspension 60 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jox 100 mg Suspension 60 ml:
Coadministration of Jox 100 mg Suspension 60 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Jox 100 mg Suspension 60 ml:
Coadministration of Jox 100 mg Suspension 60 ml with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Jox 100 mg Suspension 60 ml with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinMesoridazine
Critical
How does the drug interact with Jox 100 mg Suspension 60 ml:
Using Mesoridazine together with Jox 100 mg Suspension 60 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Jox 100 mg Suspension 60 ml is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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  • Dairy and Calcium-Rich Foods: Milk, yoghurt, or calcium-fortified juices can bind to the medicine in the gut and prevent it from being absorbed properly. Give these foods at least 2 hours before or after the medicine.
     
OFLOXACIN-100MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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OFLOXACIN-100MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
Jox 100 mg Suspension 60 ml and a multivitamin with minerals should not be taken together orally. Products containing magnesium, aluminium, calcium, iron, or other minerals may decrease the effects of Jox 100 mg Suspension 60 ml. If at all possible, avoid taking multivitamins containing minerals while receiving Jox 100 mg Suspension 60 ml treatment. Do not discontinue any medications without first consulting your doctor.

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Jox 100 mg Suspension is used to treat Bacterial infections.
No, Jox 100 mg Suspension is not used to treat viral infections. Jox 100 mg Suspension is an antibiotic that is used to treat only bacterial infections.
No. As it is an antibiotic, it is advised to complete the entire treatment course of your child as prescribed. If the treatment is stopped abruptly, there may be drug resistance.
Jox 100 mg Suspension can cause diarrhoea in children. Jox 100 mg Suspension is an antibiotic that kills toxic bacteria, but it can also affect the useful bacteria in your intestine or stomach and lead to diarrhoea. If your child has diarrhoea that is watery or bloody, call your doctor. Do not use anti-diarrhoea medicine unless your paediatrician recommends it.
Jox 100 mg Suspension may increase the risk of muscle damage in rare cases, particularly in individuals with pre-existing muscle conditions like myasthenia gravis. If you experience muscle pain, tenderness, or weakness, seek medical attention promptly.
Jox 100 mg Suspension works by killing bacteria that cause infections. It inhibits the repairing of bacterial cells and kills the bacteria, thereby preventing the further spread of the infection.
Jox 100 mg Suspension effectively treats infections by targeting and eliminating the bacteria that cause them. Through its antibacterial properties, Jox 100 mg Suspension halt the growth and spread of the infection, helping to prevent further complications and promote recovery.
Before taking Jox 100 mg Suspension, it's essential to consult your doctor about potential interactions with other medications. To ensure safe treatment, discuss your ongoing medications and medical history with your doctor, and they will help you manage any potential interactions.
It is unknown whether Jox 100 mg Suspension will affect pregnant women or fetus or not. Hence, the intake of Jox 100 mg Suspension should be avoided if you are pregnant or planning to become pregnant as it may harm the baby.
You may experience sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching in women, vaginal inflammation (vaginitis) and taste changes in some cases. Most of these side effects of Jox 100 mg Suspension do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath, immediately contact the doctor.
Do not take more than the prescribed dose of Jox 100 mg Suspension as it may cause overdose. The symptoms of overdose include nausea, dizziness, slurred speech, confusion, hot and cold flushes or numbness and swelling of the face. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
Your child does not usually need to avoid dairy foods completely while taking Jox 100 mg Suspension. However, calcium and other minerals may affect the absorption of some oral ofloxacin products. Follow the instructions for your child's specific product, and ask your doctor or pharmacist if you are unsure whether the dose needs to be separated from milk, yoghurt, calcium-fortified foods, or mineral supplements.
Do not repeat the dose without medical advice. It may be difficult to know how much medicine your child absorbed before vomiting. Contact your child's doctor or pharmacist, who can advise whether another dose is needed based on when the vomiting occurred and your child's treatment plan.
Your child can usually continue appropriate daily activities if they feel well, unless their doctor advises otherwise. Ofloxacin can rarely affect joints or tendons (strong tissues that connect muscles to bones). Contact your child's doctor promptly if your child develops new pain, swelling, tenderness, or difficulty walking, and follow their advice about activity.
Storage instructions can vary between ofloxacin oral products. Check the product label for the recommended storage conditions and how long the medicine can be kept after opening or preparation. Ask your pharmacist if the instructions are unclear.
Ofloxacin may make the skin more sensitive to sunlight in some children. Protecting exposed skin with clothing and suitable sunscreen can help while your child is outdoors. Contact your child's doctor if your child develops an unusual or significant skin reaction after sun exposure.
Ofloxacin belongs to a group of antibiotics called fluoroquinolones. Their use in children is generally limited because of concerns about uncommon effects on joints and tendons. A doctor may consider ofloxacin for certain bacterial infections when other suitable antibiotics are not appropriate or are unlikely to work, after weighing the expected benefits and possible risks.
Contact your child's doctor promptly if your child develops a new rash, itching, or other symptoms that may suggest an allergic reaction. Seek urgent medical help if your child has difficulty breathing or swelling of the face, lips, tongue, or throat.

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Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - JOX0006
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