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compositionComposition:REMDESIVIR-100MG
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Prescription Medicine
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Jubi-R 100mg Injection is used to treat coronavirus disease requiring hospitalisation. It contains Remdesivir, which works by inhibiting an enzyme that helps the coronavirus to replicate itself. In some cases, this medicine may cause side effects such as nausea, increased transaminase levels, and increased prothrombin time. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

REMDESIVIR-100MG

Manufacturer/Marketer :

Jubilant Lifesciences Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Jubi-R 100mg Injection

Jubi-R 100mg Injection is an antiviral prescription medicine given by intravenous infusion to treat severe viral respiratory infections, such as coronavirus disease (COVID-19). It is typically prescribed for patients hospitalised with severe illness or those at high risk of progressing to severe disease. This medication helps by slowing down the replication of the virus in the body.

This medicine is given as a daily infusion for a short course of treatment, and completing the full course as directed is crucial for its effectiveness. Because it is injected directly into a vein, you do not need to worry about taking it with or without food. To support your body during treatment, it is highly recommended to follow healthy lifestyle habits, such as getting plenty of rest and staying well-hydrated.

While using Jubi-R 100mg Injection, some people may experience mild side effects like nausea or headaches. However, it can occasionally cause more serious issues, such as temporary liver stress or severe allergic reactions during the infusion. You must notify your healthcare provider immediately if you experience signs like yellowing of the skin or eyes, severe stomach discomfort, or breathing difficulties.

Before starting this treatment, always discuss your complete medical history with your doctor, especially if you have pre-existing liver disease or kidney issues. Do not take this if you have had a severe allergic reaction to this medication or any of its ingredients in the past.

It is also important to tell your doctor about all other medications you are taking, as some drugs, like certain antimalarial medicines, can lower its effectiveness. Make sure to consult your healthcare provider if you are pregnant, planning to become pregnant, breastfeeding, or if you are managing health conditions in an elderly family member.

Jubi-R 100mg Injection is a prescription-only medicine and is administered only in authorised hospitals or healthcare facilities under medical supervision in India.

Uses of Jubi-R 100mg Injection

Jubi-R 100mg Injection helps control viral infections by limiting the virus's ability to multiply, supporting the body's natural immune response.

  • COVID-19 (Coronavirus Disease 2019): Jubi-R 100mg Injection helps by stopping the virus from multiplying in the body, which can reduce the severity of the infection and lower the risk of severe complications.
  • Severe Viral Infections: For hospitalized patients with severe lung infections caused by susceptible viruses, this medicine helps slow viral growth, assisting the immune system in fighting off the infection.

Key Benefits

This medication offers crucial clinical support for patients fighting severe viral infections. By targeting the virus directly, it helps you recover and return to your normal routine sooner.

  • Faster Recovery: Clinical studies show that patients receiving this treatment often experience a shorter duration of severe symptoms and recover quicker.
  • Reduced Hospitalization Risk: When given early to high-risk outpatients, it significantly lowers the likelihood of needing hospital admission.
  • Protection of Lung Function: By halting rapid viral replication, it helps prevent the severe inflammatory damage that can harm your respiratory system.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Jubi-R 100mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Jubi-R 100mg Injection Works

Jubi-R 100mg Injection contains Remdesivir, an antiviral medicine that works by directly blocking the virus's ability to multiply. Inside your cells, the virus relies on a specific enzyme to make copies of its genetic material. This medicine is designed to mimic one of the natural building blocks that the virus needs to build its genetic chain. When the virus mistakenly uses Jubi-R 100mg Injection instead of the natural building block, the copying process is cut short. This prevents the virus from replicating further, lowering the amount of virus in your body and allowing your immune system to successfully clear the infection.
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Alcohol

Caution

It is not known whether Jubi-R 100mg Injection interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

There is insufficient data regarding the safety of Jubi-R 100mg Injection during pregnancy. Please consult a doctor if you are pregnant or think you might be pregnant.

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Breast Feeding

Caution

There is insufficient data regarding the passage of Jubi-R 100mg Injection into breastmilk. Please consult a doctor if you are breastfeeding.

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Driving

Caution

It is unknown if Jubi-R 100mg Injection affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

The effectiveness of Jubi-R 100mg Injection in patients with liver impairment have not been evaluated. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

The effectiveness of Jubi-R 100mg Injection in patients with kidney impairment have not been evaluated. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Please consult your doctor if you have any concerns regarding the usage of Jubi-R 100mg Injection in children.

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Heart

Caution

Jubi-R 100mg Injection should be administered with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before receiving Jubi-R 100mg Injection.

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Geriatrics

Caution

Jubi-R 100mg Injection should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Jubi-R 100mg Injection

Because a trained healthcare professional prepares and injects this medication, an overdose is extremely rare. In the unlikely event that you suspect an overdose or experience severe side effects, seek immediate medical attention.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water, clear broths, or electrolyte solutions to support your kidney function while your body processes the medicine.
  • Prioritize rest: Give your body the rest it needs to fight off the viral infection and support faster cellular recovery.
  • Eat gentle meals: If you experience nausea, opt for small, bland, and easily digestible meals like crackers, toast, or rice instead of heavy or greasy foods.
  • Avoid alcohol: Do not drink alcohol during your treatment course, as it can place extra strain on your liver.
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How Soon It Starts Working

The time required for Jubi-R 100mg Injection to start to work: The time required for Jubi-R 100mg Injection to show its action is unknown. The time for which the effects of Jubi-R 100mg Injection last: The duration of action for Jubi-R 100mg Injection is clinically unknown.

What if you forget to take Jubi-R 100mg Injection

Since this medicine is injected by a healthcare professional in a clinical setting, a missed dose is highly unlikely. However, if you miss or must reschedule an appointment for your infusion, contact your healthcare provider immediately to arrange the next dose.

Storage

•Store the unopened dry powder vials at room temperature between 20°C and 25°C (68°F to 77°F). •Keep the vials in their original carton to protect them from light.

Drug Warnings

  • Blood tests: Your doctor will monitor your liver and kidney function before and during treatment.
  • Injection site: Tell your nurse or doctor immediately if you notice pain, burning, coldness, or swelling at the infusion site.
  • Infusion reactions: Inform your healthcare team right away if you feel dizzy, warm, shaky, or develop itching or a skin rash during the infusion.
  • Check the solution: The infusion solution should be clear and colourless to pale yellow. Do not use it if it appears cloudy, discoloured, or contains visible particles.
  • Medical history: Inform your healthcare provider about all your medical conditions, especially if you have liver or kidney disease.

Drug-Drug Interactions

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Inform your doctor if you are taking any of the following medicines, as they may interact with Jubi-R 100mg Injection: 

  • Chloroquine phosphate and hydroxychloroquine sulfate: Avoid using these medicines with Jubi-R 100mg Injection, as they may reduce its antiviral effectiveness.
  • Medicines that affect how your liver or kidneys process medicines: Some medicines may change how Jubi-R 100mg Injection is broken down or removed from your body. Your doctor will review all the medicines you take and decide if any additional monitoring or dose adjustments are needed.

Drug-Drug Interactions

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How does the drug interact with Jubi-R 100mg Injection:
Coadministration of chloroquine and Jubi-R 100mg Injection can reduce the effects of Jubi-R 100mg Injection.

How to manage the interaction:
Although there is an interaction between Chloroquine and Jubi-R 100mg Injection, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Jubi-R 100mg Injection:
Hydroxychloroquine may interfere with the antiviral activity of Jubi-R 100mg Injection and make it less effective in treating the infection.

How to manage the interaction:
Co-administration of Hydroxychloroquine and Jubi-R 100mg Injection can lead to an interaction. It can be taken if advised by your doctor. If you experience any symptoms, contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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  • No clinically significant food interactions are known with Jubi-R 100mg Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Jubi-R 100mg Injection binds to the RNA polymerase enzyme, an enzyme that helps the coronavirus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, Jubi-R 100mg Injection lowers the virus load in the body and helps treat the infection.
Jubi-R 100mg Injection should not be taken along with chloroquine phosphate and hydroxychloroquine sulphate as it might cause reduced anti-viral activity of Jubi-R 100mg Injection. Co-administration of these drugs is not recommended.
No, Jubi-R 100mg Injection is not indicated for the prevention of coronavirus disease. Jubi-R 100mg Injection has been approved by DCGI (Drug Control General of India) for emergency use only in patients who are COVID-positive.
Regularly clean your hands thoroughly using soap and water or an alcohol-based sanitiser. Avoid touching your nose, eyes, and mouth without washing your hands. Clean and disinfect surfaces regularly. Always remember to wear a mask, maintain social distance and avoid gatherings.
Covid-19 spreads through respiratory droplets when in close or direct contact with an infected person. The virus can spread through an infected person’s sneeze or cough. The virus can also be transmitted by touching any contaminated surfaces and then touching the nose, mouth or eyes without washing the hands.
Jubi-R 100mg Injection belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor used to treat coronavirus disease requiring hospitalisation.
Inform your doctor, if you are allergic to any of its contents. If you have heart, liver or kidney problems or if you are using any other medications. And also let your doctor know if you are breastfeeding, pregnancy or planning pregnancy before starting Jubi-R 100mg Injection to avoid possible interactions.
COVID-19 is a respiratory illness caused by the SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) virus. The common symptoms of corona virus disease are dry cough, breathlessness, shortness of breath, tiredness, fever, loss of sense of taste and smell, diarrhoea, body pains, headache and sore throat.
An Emergency Use Authorization (EUA) is a mechanism used by the U.S. food and drug administration (FDA) to expedite the availability and use of medical products, such as drugs and vaccines, during public health emergencies. EUA's are typically issued during situations like the COVID-19 pandemic to quickly provide access to critical medical countermeasures.
Jubi-R 100mg Injection is administered intravenously (IV), by a healthcare professional in a hospital or healthcare setting. Do not self-administer.
Jubi-R 100mg Injection is used to treat hospitalized patients who are suffering with severe COVID-19.
The common side effects of Jubi-R 100mg Injection are nausea, increased transaminase levels and increased prothrombin time. If any of these side effects persist or worsen, please consult your doctor.
Yes, Jubi-R 100mg Injection is generally considered safe when used under the supervision of a healthcare professional. However, like all medications, it can have side effects. So it's important to monitor for any adverse reactions and inform your doctor if you any side effects persist or worsen.
If you are suffering from diabetes and high blood pressure, you should take your doctor’s advice before taking Jubi-R 100mg Injection.
Jubi-R 100mg Injection should only be administered to those with laboratory-confirmed COVID-19 infection to ensure its appropriate use and effectiveness. However, consult your doctor, if you are highly suspected with COVID -19 symptoms.
This medication is typically administered in a clinical setting like a hospital or outpatient centre. In some specific cases, a qualified home healthcare nurse may inject it under direct medical supervision. Talk to your doctor to understand the safest setting for your treatment.
The number of daily infusions you need is based on the severity of your infection and your overall health. It is typically prescribed for 3 to 5 days, but your healthcare provider will decide the exact duration. Talk to your doctor for more details.
Jubi-R 100mg Injection is an antiviral medicine that helps stop the virus from multiplying, which helps your body fight off the infection and recover faster, but it is not a guaranteed cure for everyone. Talk to your doctor about your complete treatment plan.
This medicine should only be used during pregnancy or while breastfeeding if the potential benefits outweigh the risks to the baby. If you are pregnant or nursing, talk to your doctor to make an informed and safe decision.
Nausea is a common side effect of this medicine. Eating small, bland meals and staying well-hydrated can help ease this symptom, but if the nausea becomes severe or causes vomiting, talk to your doctor immediately.
This medication can temporarily raise liver enzymes, which indicates mild liver stress. Your healthcare provider will perform regular blood tests to monitor your liver health during treatment. If you notice signs like yellowing of your skin or eyes, dark urine, or severe stomach pain, talk to your doctor right away.
Signs of an infusion reaction or allergic response include sweating, shivering, dizziness, rapid heart rate, wheezing, or difficulty breathing. Healthcare professionals will monitor you closely during the process to handle any reactions. If you feel unwell during the infusion, talk to your doctor or nurse immediately.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

1A, Sector 16A, Noida - 201 301, Uttar Pradesh, India
Other Info - JUB0045
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