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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ketamine 50 mg Injection is an anaesthetic agent used to induce anaesthesia during routine and emergency surgery to prevent pain and discomfort. It contains Ketamine, which works by inducing anaesthesia by causing reversible loss of consciousness. It puts you to sleep and helps prevent pain and discomfort during surgery or other procedures. In some cases, this medication may cause nausea, vomiting, pain and inflammation at the site of injection.

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Whats That

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Synonym :

KETAMINE HYDROCHLORIDE

Composition :

KETAMINE-50MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Ketamine 50 mg Injection

Ketamine 50 mg Injection belongs to the group of medicines called anaesthetic agents indicated alone or in combination with other anaesthetic agents for the induction of anaesthesia during routine and emergency surgery to prevent pain and discomfort.

Ketamine 50 mg Injection contains Ketamine, which works by inducing anaesthesia by causing reversible loss of consciousness. It puts you to sleep and helps prevent pain and discomfort during surgery or other procedures.

In some cases, Ketamine 50 mg Injection may cause nausea, vomiting, pain and inflammation at the site of injection. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult the doctor if you are pregnant or breastfeeding. Do not drive or operate machinery for at least 24 hours after receiving Ketamine 50 mg Injection. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Ketamine 50 mg Injection

An anesthetic used to put you to sleep for surgery, to relieve pain and discomfort, to treat depression, and as an addictive drug

Directions for Use

Ketamine 50 mg Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Ketamine 50 mg Injection belongs to the group of medicines called anaesthetic agents indicated alone or in combination with other anaesthetic agents for the induction of anaesthesia during routine and emergency surgery to prevent pain and discomfort. Ketamine 50 mg Injection contains Ketamine, which works by inducing anaesthesia by causing reversible loss of consciousness. It puts you to sleep and helps prevent pain and discomfort during surgery or other procedures.

How Ketamine 50 mg Injection Works

Ketamine 50 mg Injection contains Ketamine, which works by inducing anaesthesia by causing reversible loss of consciousness. It puts you to sleep and helps prevent pain and discomfort during surgery or other procedures.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ketamine 50 mg Injection 10 ml
  • Discuss with your doctor to adjust your medications and find the right treatment for your body.
  • Do regular aerobic exercise, like walking or cycling, to boost your cardiovascular health.
  • Activities like meditation, deep breathing, or yoga help relieve anxiety and prevent increased cardiac output.
  • Eat a balanced diet and maintain a healthy weight to support your heart functioning.
  • Avoid very hot showers and baths to prevent increased heart output.
  • Quit smoking, avoid nicotine products, and limit caffeine intake.
  • Seek immediate medical help if you experience severe symptoms like chest pain, shortness of breath, or dizziness.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
  • Do calming things before bed to help you sleep.
  • Go to bed and wake up at the same time every day to keep a regular sleep routine.
  • Exercise often to reduce stress.
  • Do not use phones or laptops before bed.
  • Do not eat big meals before bedtime.
  • Limit coffee and nicotine.
  • Drink enough water.
  • Try relaxation techniques like meditation or yoga.
  • Write down your dreams to understand them better.
  • Relax your muscles to reduce stress.
  • Sleep for 7-8 hours every night.
  • Use calming scents like lavender.
  • Get help from a doctor if vivid dreams affect your life.
  • Your doctor can provide you with some medications to reduce the production of cerebrospinal fluid and subsequently lower intracranial pressure.
  • Tell your doctor immediately when you feel more severe symptoms like changes in vision, confusion, or even seizure.
  • Take fruits, vegetables, lean proteins, and whole grains to maintain a balanced diet.
  • Reduce your intake of sodium for better fluid retention and lower blood pressure.
  • Keep yourself fit with a healthy weight to decrease intracranial pressure.
  • Yoga, meditation, and deep breathing will help reduce your stress levels.
  • Regularly visiting the doctor helps monitor progress, health of eyes, and intracranial pressure.

What if I have taken an overdose of Ketamine 50 mg Injection

As Ketamine 50 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Ketamine 50 mg Injection may cause amnesia, elevated blood pressure, breathing difficulties, problems with coordination and judgment, seizures, ulcerative cystitis and addiction.

Drug Warnings

Do not use Ketamine 50 mg Injection if you are allergic to any of its components if you are suffering from any condition in which an increase in blood pressure may be harmful to you, if you have been pregnant, and during your pregnancy, you have suffered from a condition called eclampsia or pre-eclampsia which causes an increase in your blood pressure, if you have/had stroke, serious head or brain injury, or severe heart disease. Inform the doctor if you have/had mental health problems, chest infection, breathing problems, liver problems, glaucoma, porphyria, seizures, thyroid disorder, head injury or abnormal growth in the brain, if you drink large amounts of alcohol or if you have a history of drug abuse or addiction. Consult the doctor if you are pregnant or breastfeeding. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal supplements.

Drug-Drug Interactions

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KetamineLorazepam
Severe
KetamineDiphenhydramine
Severe

Drug-Drug Interactions

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KetamineLorazepam
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Using Lorazepam together with Ketamine 50 mg Injection 10 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
There may be a possibility of interaction between Ketamine 50 mg Injection 10 ml and Lorazepam, but it can be taken if prescribed by a doctor. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
KetamineDiphenhydramine
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Taking Ketamine 50 mg Injection 10 ml with diphenhydramine can increase the risk of side effects.

How to manage the interaction:
Although taking Diphenhydramine with Ketamine 50 mg Injection 10 ml can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience severe dizziness, confusion, drowsiness, confusion, difficulty concentrating, or excessive sleepiness consult your doctor immediately. Do not discontinue using any medications without consulting a doctor.
KetamineZolpidem
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Taking zolpidem with Ketamine 50 mg Injection 10 ml increases the effects of zolpidem. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketamine 50 mg Injection 10 ml and zolpidem together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
KetamineClozapine
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
When Clozapine is taken with Ketamine 50 mg Injection 10 ml, may increase side effects.

How to manage the interaction:
Co-administration of Ketamine 50 mg Injection 10 ml with Clozapine can possibly result in an interaction, but it can be taken if a doctor has advised it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
KetamineTrazodone
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Using Ketamine 50 mg Injection 10 ml together with trazodone may increase the risk of side effects.

How to manage the interaction:
Co-administration of Ketamine 50 mg Injection 10 ml with Trazodone can possibly result in an interaction, but can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation(sleepiness), and respiratory depression(breathing problem). Do not discontinue any medications without consulting your doctor.
KetamineAlprazolam
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Using Alprazolam together with Ketamine 50 mg Injection 10 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Alprazolam and Ketamine 50 mg Injection 10 ml may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.
KetamineDiazepam
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Co-administration of Diazepam with Ketamine 50 mg Injection 10 ml can increase the risk of CNS depression.

How to manage the interaction:
Taking Ketamine 50 mg Injection 10 ml with Diazepam together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
KetamineTramadol
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
The combined use of tramadol with Ketamine 50 mg Injection 10 ml can make tramadol less effective as a treatment.

How to manage the interaction:
Taking ketaminewith tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetamineFluvoxamine
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Combining Ketamine 50 mg Injection 10 ml with Fluvoxamine can increase the likelihood and seriousness of negative side effects.

How to manage the interaction:
Co-administration of Ketamine 50 mg Injection 10 ml with Fluvoxamine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact your doctor right away. Do not discontinue any medications without consulting your doctor.
KetamineLevetiracetam
Severe
How does the drug interact with Ketamine 50 mg Injection 10 ml 50 mg Injection 10 ml:
Using Ketamine 50 mg Injection 10 ml together with levetiracetam may increase side effects (dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression).

How to manage the interaction:
Although there is a possible interaction between Ketamine 50 mg Injection 10 ml and Levetiracetam, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Yes

Therapeutic Class

GENERAL ANESTHETICS

Ketamine 50 mg Injection Substitute

Substitutes safety advice
  • Aneket 500 Injection 10 ml

    by Others

    12.20per tablet
  • Aneket 50 mg Injection 1's

    by Others

    57.28per tablet
  • CELTAMIN 50MG INJECTION 10ML

    by Others

    9.72per tablet
  • Ketmin 50 mg Injection 10 ml

    by Others

    9.34per tablet
  • Ketamin 50 mg Injection 1's

    by Others

    103.05per tablet
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Alcohol

Caution

Avoid consumption of alcohol during treatment with Ketamine 50 mg Injection.

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Pregnancy

Caution

If you are pregnant, think you may be pregnant or planning for pregnancy, inform the doctor before receiving Ketamine 50 mg Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Ketamine 50 mg Injection.

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Driving

Unsafe

Ketamine 50 mg Injection may impair your thinking and reactions. Therefore, avoid driving and operating machinery for at least 24 hours after receiving Ketamine 50 mg Injection.

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Liver

Caution

If you have a history of liver impairment, inform the doctor before receiving Ketamine 50 mg Injection.

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Kidney

Caution

If you have a history of kidney impairment, inform the doctor before receiving Ketamine 50 mg Injection.

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Children

Caution

The safety and effectiveness in children below 16 years have not been established. However, please consult your doctor for more information.

FAQs

Ketamine 50 mg Injection is used to induce anaesthesia during routine and emergency surgery to prevent pain and discomfort.

Ketamine 50 mg Injection puts you to sleep and helps prevent pain and discomfort during surgery or other procedures.

Ketamine 50 mg Injection may not be safe for people in whom significant elevation of blood pressure may be harmful. If you have hypertension/high blood pressure, inform the doctor.

Ketamine 50 mg Injection may cause hallucinations, which might include flashbacks or floating sensations. Consult the doctor if you experience hallucinations.

Ketamine 50 mg Injection is an addictive medication. Especially, when prolonged or excessive use. It has a potential for abuse and can lead to psychological dependence. Therefore, follow your doctor's instructions carefully.

Ketamine 50 mg Injection is a controlled substance, but not an opioid, stimulant, narcotic, or barbiturate.

Ketamine 50 mg Injection is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.

Ketamine 50 mg Injection can be dangerous if misused, taken in excess, or not used as instructed by the doctor.

Generally, Ketamine 50 mg Injection does not make you lose weight, but some patients may experience weight loss due to decreased appetite. If you have any concerns discuss them with your doctor.

The common side effects of Ketamine 50 mg Injection which may occur in some individuals are nausea, vomiting, pain, and inflammation at the site of injection. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7Th To 12Th Floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103.
Other Info - KET0461

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