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compositionComposition:KETAMINE-50MG
prescription
Prescription Medicine
info
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Ketsia 50 mg Injection is an anaesthetic agent used to induce anaesthesia during routine and emergency surgery to prevent pain and discomfort. It contains Ketamine, which works by inducing anaesthesia by causing reversible loss of consciousness. It puts you to sleep and helps prevent pain and discomfort during surgery or other procedures. In some cases, this medication may cause nausea, vomiting, pain and inflammation at the site of injection.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

KETAMINE-50MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Ketsia 50 mg Injection

Ketsia 50 mg Injection is a prescription general anaesthetic injection used by healthcare professionals to provide anaesthesia for diagnostic and surgical procedures. It is indicated as the sole anaesthetic agent for procedures that do not require skeletal muscle relaxation, for the induction of anaesthesia before other general anaesthetics, and as a supplement to other anaesthetic agents. It is especially useful for short procedures, though it can also be used with additional doses when longer anaesthesia is required. 

Because Ketsia 50 mg Injection is given by injection, it is used only in monitored clinical settings such as hospitals or surgical centres. The dose is individualised, and the medicine is administered by clinicians experienced in airway management, oxygenation, and ventilation. Before treatment, patients are generally required to fast, because Ketsia 50 mg Injection is not recommended when nil per os instructions have not been followed. 

While receiving Ketsia 50 mg Injection, some people may experience nausea, vomiting, dizziness, vivid dreams, confusion, or temporary increases in blood pressure and heart rate during recovery. Emergence reactions can occur as the medicine wears off. However, you must alert your healthcare team immediately if you develop severe breathing difficulty, marked confusion, hallucinations, or a serious allergic reaction. 

Do not use this medicine if a significant rise in blood pressure would be a serious hazard, or if you have a known allergy to Ketsia 50 mg Injection or any excipient. Tell your doctor before treatment if you have uncontrolled hypertension, heart disease, elevated intracranial pressure, or a psychiatric condition, because Ketsia 50 mg Injection can raise blood pressure and has been associated with emergence reactions and other psychiatric effects. 

This medicine can interact with benzodiazepines, opioid analgesics, other CNS depressants, theophylline or aminophylline, and sympathomimetics or vasopressin. If you are pregnant, breastfeeding, an older adult, or have other chronic medical conditions, your healthcare team will weigh the risks and benefits carefully before giving this medicine.

Uses of Ketsia 50 mg Injection

Your doctor may prescribe Ketsia 50 mg Injection to treat the following conditions:

  • Starting anaesthesia: Helps induce anaesthesia before a procedure or before other general anaesthetic agents are given.
  • Maintaining anaesthesia: May be used as a supplement to other anaesthetic agents during surgery or diagnostic procedures.
  • Short diagnostic or surgical procedures: Used as the sole anaesthetic agent for procedures that do not require skeletal muscle relaxation.

Key Benefits

Ketsia 50 mg Injection provides rapid anaesthesia for procedures that need quick onset and close monitoring. Because it acts fast after injection, it helps medical teams begin treatment or surgery without unnecessary delay and keeps the patient unconscious and pain-free during the procedure. 

  • Rapid onset for procedures: Starts working quickly, making it useful when anaesthesia must be established promptly.
  • Useful for short procedures: Especially suitable for brief diagnostic or surgical procedures that do not require skeletal muscle relaxation.
  • Can supplement other anaesthetics: May be combined with other anaesthetic agents to support balanced anaesthesia.
  • Provides dissociative anaesthesia: Helps block awareness of pain and sensory input during the procedure.
Side effects of Ketsia 50 mg Injection 10 ml
  • Discuss with your doctor to adjust your medications and find the right treatment for your body.
  • Do regular aerobic exercise, like walking or cycling, to boost your cardiovascular health.
  • Activities like meditation, deep breathing, or yoga help relieve anxiety and prevent increased cardiac output.
  • Eat a balanced diet and maintain a healthy weight to support your heart functioning.
  • Avoid very hot showers and baths to prevent increased heart output.
  • Quit smoking, avoid nicotine products, and limit caffeine intake.
  • Seek immediate medical help if you experience severe symptoms like chest pain, shortness of breath, or dizziness.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
  • Do calming things before bed to help you sleep.
  • Go to bed and wake up at the same time every day to keep a regular sleep routine.
  • Exercise often to reduce stress.
  • Do not use phones or laptops before bed.
  • Do not eat big meals before bedtime.
  • Limit coffee and nicotine.
  • Drink enough water.
  • Try relaxation techniques like meditation or yoga.
  • Write down your dreams to understand them better.
  • Relax your muscles to reduce stress.
  • Sleep for 7-8 hours every night.
  • Use calming scents like lavender.
  • Get help from a doctor if vivid dreams affect your life.
  • Your doctor can provide you with some medications to reduce the production of cerebrospinal fluid and subsequently lower intracranial pressure.
  • Tell your doctor immediately when you feel more severe symptoms like changes in vision, confusion, or even seizure.
  • Take fruits, vegetables, lean proteins, and whole grains to maintain a balanced diet.
  • Reduce your intake of sodium for better fluid retention and lower blood pressure.
  • Keep yourself fit with a healthy weight to decrease intracranial pressure.
  • Yoga, meditation, and deep breathing will help reduce your stress levels.
  • Regularly visiting the doctor helps monitor progress, health of eyes, and intracranial pressure.

Directions for Use

  • Ketsia 50 mg Injection will be administered by a healthcare professional.
  • Do not self-administer it.

How Ketsia 50 mg Injection Works

Ketsia 50 mg Injection contains ketamine which belongs to a group of medicines called general anaesthetics and produces dissociative anaesthesia. It works by blocking the brain pathways involved in pain perception and consciousness, so the patient becomes insensitive to pain and less aware of the procedure. During this state, the patient may not fully perceive pain, sound, or touch, which allows the medical team to perform the procedure while maintaining anaesthetic control. Ketsia 50 mg Injection also has sympathomimetic effects, which help explain why blood pressure and heart rate often rise after administration.
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Alcohol

Caution

Avoid consumption of alcohol during treatment with Ketsia 50 mg Injection.

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Pregnancy

Caution

If you are pregnant, think you may be pregnant or planning for pregnancy, inform the doctor before receiving Ketsia 50 mg Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Ketsia 50 mg Injection.

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Driving

Unsafe

Ketsia 50 mg Injection may impair your thinking and reactions. Therefore, avoid driving and operating machinery for at least 24 hours after receiving Ketsia 50 mg Injection.

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Liver

Caution

If you have a history of liver impairment, inform the doctor before receiving Ketsia 50 mg Injection.

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Kidney

Caution

If you have a history of kidney impairment, inform the doctor before receiving Ketsia 50 mg Injection.

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Children

Caution

The safety and effectiveness in children below 16 years have not been established. However, please consult your doctor for more information.

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Heart

Caution

Ketsia 50 mg Injection should be used with caution in heart patients, as it can raise blood pressure, heart rate, and increase the risk of arrhythmias. If you have conditions like uncontrolled hypertension or heart failure, consult your doctor to assess safety before use.

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Geriatrics

Caution

Geriatric patients can receive Ketsia 50 mg Injection, especially under medical supervision for conditions like depression or anesthesia. However, age-related changes in metabolism and sensitivity to side effects like dizziness or elevated blood pressure require careful monitoring.

What if I have taken an overdose of Ketsia 50 mg Injection

Overdose is uncommon under direct medical supervision, but too much Ketsia 50 mg Injection can prolong recovery and increase the risk of breathing problems and blood pressure changes. Emergency supportive care, including ventilation support, may be required.

Diet & Lifestyle Advise

  • Follow fasting instructions carefully: Do not eat or drink for the period instructed before your procedure, because Ketsia 50 mg Injection is not recommended if nil per os guidance has not been followed.
  • Arrange an adult escort: Plan for someone to take you home and stay with you after the procedure because recovery from anaesthesia may involve drowsiness or confusion.
  • Rest after the procedure: Allow yourself time to recover quietly after anaesthesia and avoid strenuous activity until your clinician says it is safe.
  • Avoid alcohol and sedatives: Alcohol, sleeping pills, opioids, and other CNS depressants can worsen sedation and breathing problems.
  • Follow the recovery plan: Keep all post-procedure instructions, including wound care, medication advice, and follow-up appointments.
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Have a query?

How Soon It Starts Working

The time required for Ketsia 50 mg Injection to start to work: Ketsia 50 mg Injection ideally starts working within 30 seconds after an intravenous dose and 3 to 4 minutes after an intramuscular administration. The time for which the effects of Ketsia 50 mg Injection last: The effect of Ketsia 50 mg Injection lasts for 5 to 10 minutes after an intravenous dose and 12 to 25 minutes after an intramuscular administration.

What if you forget to take Ketsia 50 mg Injection

Because this medicine is given in a hospital or clinical setting for a specific procedure, missing a dose at home is not usually relevant. Your medical team will manage the timing of administration.

Storage

• Store Ketsia 50 mg Injection at 20°C to 25°C (68°F to 77°F), with excursions permitted between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Check the solution before use: Do not administer the medicine if it appears discoloured or contains particles.
  • Tell your team about all medicines: Benzodiazepines, opioids, other CNS depressants, theophylline/aminophylline, and sympathomimetics can affect safety during Ketsia 50 mg Injection use.
  • Monitor blood pressure and heart rate: Ketsia 50 mg Injection commonly increases these values, so close monitoring is necessary during administration.
  • Report mood or confusion symptoms: Emergence delirium or psychiatric symptoms can occur during recovery and should be reported promptly.
  • Follow fasting and recovery instructions exactly: This reduces the risk of vomiting, aspiration, and avoidable complications.

Drug-Drug Interactions

verifiedApollotooltip

  • Benzodiazepines, opioid analgesics, and other CNS depressants: May cause profound sedation, respiratory depression, coma, or death; opioids may also prolong recovery time.
  • Theophylline or aminophylline: Should not be co-administered because they may lower the seizure threshold.
  • Sympathomimetics and vasopressin: May increase haemodynamic effects, so vital signs should be closely monitored.
KetamineChlorpromazine
Severe
KetamineLemborexant
Severe

Drug-Drug Interactions

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KetamineChlorpromazine
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Taking Chlorpromazine with Ketsia 50 mg Injection 10 ml can increase the risk of serious side effects.

How to manage the interaction:
Taking chlorpromazine and Ketsia 50 mg Injection 10 ml together can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression. Do not discontinue any medications without consulting a doctor.
KetamineLemborexant
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
When Lemborexant is taken with Ketsia 50 mg Injection 10 ml, the amount of Lemborexant in the blood may decrease.

How to manage the interaction:
Although there is a possible interaction between Lemborexant and Ketsia 50 mg Injection 10 ml, you can take these medicines together if prescribed by your doctor. If you experience any dizziness, drowsiness, confusion, trouble concentrating, excessive sleepiness, or difficulty breathing, Contact your doctor immediately. Do not stop using any medications without talking to your doctor.
KetamineBuspirone
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Using Ketsia 50 mg Injection 10 ml together with Buspirone may increase side effects (dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression)

How to manage the interaction:
Co-administration of Ketsia 50 mg Injection 10 ml with Buspirone can result in an interaction, but it can be taken if a doctor has advised it. Keep an eye on your brain and breathing. If you notice any of these signs - feeling dizzy, sleepy, confused, having trouble focusing, feeling too relaxed, or having trouble breathing - reach out to your doctor right away. Do not discontinue any medications without consulting a doctor.
KetamineTetrabenazine
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Co-administration of Ketsia 50 mg Injection 10 ml with tetrabenazine may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Ketsia 50 mg Injection 10 ml and Tetrabenazine can lead to an interaction, but it can be taken if advised by your doctor. Avoid activities requiring mental alertness, such as driving, operating hazardous machinery, or engaging in potentially hazardous activities, until you know how the medications affect you. Do not discontinue any medications without consulting your doctor.
KetamineParoxetine
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Combining Ketsia 50 mg Injection 10 ml with Paroxetine can increase the risk of negative side effects.

How to manage the interaction:
Taking Paroxetine with Ketsia 50 mg Injection 10 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
KetamineTramadol
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
The combined use of tramadol with Ketsia 50 mg Injection 10 ml can make tramadol less effective as a treatment.

How to manage the interaction:
Taking ketaminewith tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetamineBrivaracetam
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Co-administration of Brivaracetam with Ketsia 50 mg Injection 10 ml may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is a possible interaction between Brivaracetam and Ketsia 50 mg Injection 10 ml, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - feeling dizzy, sleepy, confused, having trouble focusing, feeling too relaxed, or having trouble breathing - make sure to contact adoctor right away. Do not stop using any medications without talking to a doctor.
KetaminePromethazine
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Combining Promethazine with Ketsia 50 mg Injection 10 ml can increase the risk of CNS depression.

How to manage the interaction:
Although taking Ketsia 50 mg Injection 10 ml and Promethazine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, contact your doctor right away. Do not stop using any medications without talking to your doctor.
KetaminePhenytoin
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Using Ketsia 50 mg Injection 10 ml together with phenytoin may increase side effects.

How to manage the interaction:
Although taking Phenytoin and Ketsia 50 mg Injection 10 ml together can cause an interaction, it can be taken if your doctor has suggested it. It is important to closely monitor your neurological status, breathing rate, and oxygen levels in this situation. Do not stop using any medications without a doctor's advice.
KetamineDiazepam
Severe
How does the drug interact with Ketsia 50 mg Injection 10 ml:
Co-administration of Diazepam with Ketsia 50 mg Injection 10 ml can increase the risk of CNS depression.

How to manage the interaction:
Taking Ketsia 50 mg Injection 10 ml with Diazepam together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol around the time of treatment, because it can worsen sedation and respiratory depression when combined with anaesthetic medicines.
  • Food and drink before the procedure: Follow fasting instructions exactly, because Ketsia 50 mg Injection is not recommended when nil per os guidance has not been followed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Yes

Therapeutic Class

[GENERAL ANESTHETICS]

FAQs

When given directly into a vein, Ketsia 50 mg Injection begins to work almost immediately, typically within seconds. When injected into a muscle, it takes about 3 to 4 minutes to take effect. Talk to your doctor for more details.
Most patients do not remember the medical procedure because this medication causes temporary memory loss during and shortly after its administration. Talk to your doctor if you have concerns.
No, this medication must only be administered by trained medical professionals in a hospital, clinic, or emergency setting. Talk to your doctor or pharmacist.
The main anaesthetic effect usually lasts for 10 to 15 minutes after a single intravenous dose, though complete recovery of coordination and alertness can take several hours. Talk to your doctor.
This medicine is generally reserved for situations where the medical benefits clearly outweigh the potential risks to the unborn baby. Talk to your doctor.
Fasting is essential to prevent nausea and vomiting, which can cause stomach contents to accidentally enter the lungs while you are sedated. Talk to your doctor.
You should avoid alcohol for at least 24 hours after your procedure, as it can dangerously intensify the residual sedative effects of the medicine. Talk to your doctor.
These "emergence reactions" are recognised side effects that medical staff are trained to manage with quiet environments or supportive medications as you wake up. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - KET0562
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