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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ketodel Tablet is used to treat chronic kidney disease. It contains Alpha Ketoanalogue, which works by lowering urea levels in the blood and improving kidney function. In some cases, this medicine may cause side effects such as increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

ALPHA KETOANALOGUE

Manufacturer/Marketer :

Oriva Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Ketodel Tablet

Ketodel Tablet is widely used in the treatment of chronic kidney disease. Chronic kidney disease (CKD) is a long-term condition where the kidneys don't work as they should.

Ketodel Tablet contains Alpha Ketoanalogue, which prevents the unnecessary increase in urea levels in the blood due to the intake of non-essential amino acids in patients with kidney failure. Thereby improving renal function.

Not everyone who takes Ketodel Tablet will experience these side effects. Common side effects of Ketodel Tablet include increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time.

Take Ketodel Tablet with food orally (by mouth). Depending on your medical condition, your doctor will decide the dose and duration of the medicine. However, it is advised not to take more than the prescribed dose of Ketodel Tablet . Do not chew, crush or bite the medicine.

Do not take Ketodel Tablet if you are allergic to any components present in Ketodel Tablet . Inform your physician if you are pregnant or a breastfeeding mother before using Ketodel Tablet . Please do not stop taking Ketodel Tablet without consulting your doctor. Avoid consuming alcohol during the treatment to avoid unpleasant side effects.

Uses of Ketodel Tablet

Ketodel Tablet used in the treatment of chronic kidney disease (CKD). The detailed uses of Ketodel Tablet are as follows:

  • Chronic Kidney Disease (CKD): Ketodel Tablet helps to manage CKD by reducing the accumulation of nitrogen waste products in the blood, slowing disease progression, and delaying the need for dialysis.
  • Kidney Function Support: Ketodel Tablet supports kidney function by reducing uremia and waste accumulation, providing essential amino acids, and reducing the strain on the kidneys.
  • Enhances Nutritional Status: Ketodel Tablet enhances nutritional status by providing essential ketoacids, which promote protein synthesis, reduce muscle wasting, and improve overall health.

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Directions for Use

  • Ketodel Tablet can be taken with meals to increase absorption.
  • It is advised to take this medication three times daily or as prescribed by your doctor.
  • Swallow Ketodel Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Key Benefits

  • Ketodel Tablet is used in the treatment of chronic kidney disease.
  • It is best if taken along with a low-protein diet, as it helps delay the progression of kidney diseases.
  • Make healthy lifestyle changes and ensure that your underlying conditions are well-managed.

How Ketodel Tablet Works

Ketodel Tablet contains 'Alpha Ketoanalogue', which prevents the unnecessary increase in urea levels in the blood due to the intake of non-essential amino acids in patients with kidney failure. Thereby improving renal function. It is best if taken along with a low-protein diet as it helps delay the progression of kidney diseases.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ketodel Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Ketodel Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include hypotension (low blood pressure), fever, rapid pulse, and general symptoms of shock. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Ketodel Tablet if you are allergic to any components present in it. 
  • It is advised not to stop taking Ketodel Tablet without consulting your doctor.
  • Ketodel Tablet should be used in pregnant and breastfeeding women only if clinically needed and the benefits outweigh the risks.
  • Avoid consuming alcohol along with Ketodel Tablet  as it may lead to unpleasant side effects.
  • People with chronic kidney disease (CKD) may need to closely monitor sodium and phosphorus in foods, especially if their kidney disease is advanced.
  • Ketodel Tablet is not recommended for use in children below 18 years of age as the safety has not been established.

Drug-Drug Interactions

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KetoconazoleHalofantrine
Critical

Drug-Drug Interactions

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KetoconazoleHalofantrine
Critical
How does the drug interact with Ketodel Tablet:
Using Ketodel Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ketodel Tablet with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Ketodel Tablet:
Taking Ketodel Tablet and Disopyramide together can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ketodel Tablet with Disopyramide is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms like dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ketodel Tablet:
When Tolvaptan is taken with Ketodel Tablet, may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan with Ketodel Tablet is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
KetoconazoleConivaptan
Critical
How does the drug interact with Ketodel Tablet:
Using conivaptan together with Ketodel Tablet may significantly increase the blood levels of conivaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Ketodel Tablet with Conivaptan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures(fits), consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Ketodel Tablet:
Using Lurasidone together with Ketodel Tablet may increase the risk of side effects like Parkinson's disease(It is a brain disorder that produces uncontrollable movements).

How to manage the interaction:
While lurasidone and Ketodel Tablet is not recommended as it may lead to an interaction, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, fits, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketodel Tablet:
Coadministration of Lovastatin with Ketodel Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Ketodel Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleTriazolam
Critical
How does the drug interact with Ketodel Tablet:
When Triazolam is taken with Ketodel Tablet, it can increase the risk of drowsiness and slowed breathing.

How to manage the interaction:
Taking Triazolam with Ketodel Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleVoclosporin
Critical
How does the drug interact with Ketodel Tablet:
When Voclosporin is taken with Ketodel Tablet, it can increase the risk of serious side effects.

How to manage the interaction:
Taking Ketodel Tablet with Voclosporin is not recommended, it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor immediately.
How does the drug interact with Ketodel Tablet:
Coadministration of Silodosin with Ketodel Tablet may lead to side effects including extremely low blood pressure, and increased heart rate.

How to manage the interaction:
Taking Ketodel Tablet with Silodosin together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ketodel Tablet:
Co-administration of Ketodel Tablet and Isavuconazole can significantly increase the blood levels of Isavuconazole, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavuconazole with Ketodel Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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ALPHA KETOANALOGUEGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ALPHA KETOANALOGUEGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Ketodel Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Ketodel Tablet.

Diet & Lifestyle Advise

  • ​​It is best if taken along with a low-protein diet as it helps delay the progression of kidney diseases.
  • People with kidney problems are advised to limit sodium in their diet, including added salt.
  • Olive oil is a healthy source of fat- and phosphorus-free source, making it an excellent option for people with kidney disease.
  • Bulgur is a whole-grain wheat product that is a terrific, kidney-friendly alternative to other whole grains high in phosphorus and potassium.
  • Blueberries are packed with nutrients and are one of the best sources of antioxidants you can eat.

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

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Alcohol

Safe if prescribed

You are recommended not to consume alcohol along with Ketodel Tablet to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

Ketodel Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult the doctor; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Caution should be exercised, and it is advisable to consult a doctor before using it. The doctor will prescribe if the doctor thinks the benefits outweigh the risks.

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Driving

Safe if prescribed

Drive only if you are physically stable and mentally focused. If you experience drowsiness after taking this medication, you should not drive or operate machinery or vehicles.

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Liver

Consult your doctor

Inform your doctor before taking Ketodel Tablet if you have a liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Ketodel Tablet can be taken safely if prescribed. Usually, it does not affect the kidney.

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Children

Safe if prescribed

The safety and efficacy of Ketodel Tablet in children have not been established. Ketodel Tablet is not recommended in children.

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Heart

Ketodel Tablet is generally safe for heart patients, but they should be taken under medical supervision.

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Geriatrics

Consult your doctor

Geriatric patients may take Ketodel Tablet with caution, as age-related kidney or calcium metabolism changes require medical supervision. Always consult your doctor to ensure it's suitable for your health status and other medications.

FAQs

Ketodel Tablet is used in the treatment of chronic kidney disease.

Ketodel Tablet mimics the same catabolic pathways as amino acids and works by improving the body's metabolism, thereby improving renal function.

To treat your condition effectively, continue taking Ketodel Tablet for as long as your doctor has prescribed. Please do not stop taking Ketodel Tablet without consulting your doctor.

CKD is usually caused by various conditions such as high blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, kidney stones that keep coming back, an enlarged prostate, and long-term or regular use of certain medicines such as lithium and non-steroidal anti-inflammatory drugs (NSAIDs).

CKD can be diagnosed using blood and urine tests. These tests look for high levels of certain substances in the blood and urine that show your kidneys are malfunctioning. The results of these tests can be used to determine the stage of your kidney disease.

There are usually no symptoms of kidney disease in the early stages. At a more advanced stage, symptoms can include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in your pee (urine). It may only be diagnosed if you have a blood or urine test for another reason and the results show a possible problem with your kidneys.

Ketodel Tablet contains Alpha Ketoanalogue, a nutritional supplement used to treat chronic kidney disease.

No, Ketodel Tablet is not same as arginine alpha-ketoglutarate. Ketodel Tablet contains alpha ketoanalogue which is a combination of different amino acids, whereas arginine alpha-ketoglutarate is a combination of alpha-ketoglutaric acid &essential amino acid arginine.

Ketodel Tablet should be swallowed as a whole with water; do not crush or chew it.

Side effects of Ketodel Tablet include increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Talk to your doctor if you experience these side effects persistently.

Country of origin

INDIA

Manufacturer/Marketer address

306, V.I.P Plaza, Plot No. 1, I.P Ext., Delhi - 110092 (India)
Other Info - KET0206

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