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compositionComposition:ALPHA KETOANALOGUE
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Prescription Medicine
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Ketograce Tablet is used to treat chronic kidney disease. It contains Alpha Ketoanalogue, which works by lowering urea levels in the blood and improving kidney function. In some cases, this medicine may cause side effects such as increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ALPHA KETOANALOGUE

Manufacturer/Marketer :

Biokindle Lifesciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ketograce Tablet

Ketograce Tablet is a specialised medical nutrition therapy used to manage chronic kidney disease in patients with renal impairment. It is prescribed to prevent and treat damage caused by faulty protein metabolism when kidney function is reduced. By providing essential nutrients without overloading the kidneys with toxic waste, it helps maintain overall body function.

This medication must be taken consistently every day, exactly as prescribed, to be effective in managing kidney health. You should take Ketograce Tablet during your meals to help your body process and utilise the nutrients correctly. For the best results, it is crucial to combine this treatment with a strict, low-protein diet and regular physical activity recommended by your healthcare team.

While taking Ketograce Tablet , some people may experience mild side effects, such as a slight increase in calcium levels or mild stomach upset. If you notice signs of severe calcium buildup, such as extreme muscle weakness, confusion, or severe nausea, you must consult your doctor immediately.

Before starting Ketograce Tablet , talk to your doctor if you have any existing metabolic conditions or mineral imbalances. Do not take this medicine if you already have abnormally high calcium levels in your blood or if you have a hereditary disorder that affects how your body processes amino acids.

Avoid taking this medicine at the same time as certain antibiotics or iron supplements. The calcium salts present in the tablets can bind to these medicines in the gastrointestinal tract, reducing their absorption and effectiveness. Your doctor or pharmacist may recommend spacing these medicines by at least 2 hours. If you are pregnant, breastfeeding, or an elderly individual, consult your healthcare provider to ensure this treatment is safe for your specific needs.

Uses of Ketograce Tablet

Ketograce Tablet is used to manage chronic kidney disease in patients with renal impairment. The detailed uses of Ketograce Tablet are as follows:

  • Chronic Kidney Disease (CKD): Helps delay the progression of kidney damage in patients with moderate to severe kidney disease by reducing the accumulation of toxic waste products in the blood.
  • Uremia Prevention: Helps manage and prevent symptoms caused by the buildup of nitrogen-containing waste products in the blood, which happens when kidneys cannot filter properly.

Key Benefits

Ketograce Tablet helps support nutrition in people with chronic kidney disease who are following a low-protein diet. It provides essential amino acid precursors without adding a significant nitrogen load, helping reduce the build-up of waste products in the blood.

  • Supports Nutrition on a Low-Protein Diet: Ketograce Tablet helps provide the building blocks needed for protein synthesis while helping limit the burden on the kidneys.
  • Helps Reduce Uremic Waste: By improving the use of dietary protein and reducing nitrogen waste production, Ketograce Tablet may help lower the accumulation of toxic waste products associated with kidney disease.
  • May Help Preserve Kidney Function: Better metabolic control may help support remaining kidney function and may delay the need for dialysis in appropriate patients when used as part of a prescribed kidney care plan.
  • Improves Daily Wellbeing: By supporting nutritional status, Ketograce Tablet may help reduce fatigue, muscle cramps, poor appetite, nausea, and other symptoms related to advanced kidney disease, improving overall comfort and quality of life.
Side effects of Ketograce Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Ketograce Tablet can be taken with meals to increase absorption.
  • It is advised to take this medication three times daily or as prescribed by your doctor.
  • Swallow Ketograce Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Ketograce Tablet Works

Ketograce Tablet contains alpha-ketoanalogues, which are nitrogen-free precursors of essential amino acids. After absorption, these alpha-ketoacids undergo transamination, a process in which they accept an amino (nitrogen) group from non-essential amino acids or other nitrogen-containing compounds in the body, converting into essential amino acids. This allows the body to maintain protein synthesis without introducing additional dietary nitrogen, helping reduce the production and accumulation of nitrogenous waste while supporting nutritional status and limiting the workload on the kidneys in people following a low-protein diet.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Ketograce Tablet to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

Ketograce Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. Please consult the doctor; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Caution should be exercised, and it is advisable to consult a doctor before using it. The doctor will prescribe if the doctor thinks the benefits outweigh the risks.

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Driving

Caution

Drive only if you are physically stable and mentally focused. If you experience drowsiness after taking this medication, you should not drive or operate machinery or vehicles.

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Liver

Consult your doctor

Inform your doctor before taking Ketograce Tablet if you have a liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Safe if prescribed

Ketograce Tablet can be taken safely if prescribed. Usually, it does not affect the kidney.

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Children

Unsafe

The safety and efficacy of Ketograce Tablet in children have not been established. Ketograce Tablet is not recommended in children.

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Heart

Caution

Ketograce Tablet is generally safe for heart patients, but they should be taken under medical supervision.

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Geriatrics

Caution

Geriatric patients may take Ketograce Tablet with caution, as age-related kidney or calcium metabolism changes require medical supervision. Always consult your doctor to ensure it's suitable for your health status and other medications.

What if I have taken an overdose of Ketograce Tablet

If you take more than the prescribed amount, seek immediate medical attention. Symptoms of an overdose may include severe nausea, vomiting, extreme thirst, or signs of high blood calcium levels.

Diet & Lifestyle Advise

  • Follow a strict low-protein or very low-protein diet under the close supervision of a clinical dietitian or your doctor to ensure the medication works as intended.
  • Ensure you consume enough daily calories from non-protein sources, such as healthy fats and carbohydrates, to prevent your body from breaking down its own muscle tissue for energy.
  • Keep all laboratory appointments to monitor your blood calcium, phosphate, and kidney function levels regularly.
  • Stay adequately hydrated, but strictly follow any fluid restriction guidelines provided by your kidney specialist.
health query

Have a query?

How Soon It Starts Working

The time required for Ketograce Tablet to start to work: The time required for Ketograce Tablet to show its action is not clinically established. 

The time for which the effects of Ketograce Tablet last: The duration of action for Ketograce Tablet is not clinically established.

What if you forget to take Ketograce Tablet

Take the missed dose as soon as you remember, provided it is during or immediately after a meal. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Ketograce Tablet at room temperature below 30°C, unless otherwise specified on the product label.

Drug Warnings

  • Always inspect the blister packaging before use; do not take the medication if the foil is broken or damaged.
  • Ensure you have your blood calcium levels checked regularly, as this medicine can cause calcium buildup.
  • Do not take calcium supplements, antacids containing calcium, or vitamin D preparations without talking to your doctor first.
  • Always take this medicine during meals to maximise its nutritional effectiveness and prevent stomach upset.

Drug-Drug Interactions

verifiedApollotooltip
  • Antibiotics and Iron: May reduce the absorption of certain antibiotics (such as tetracyclines and quinolones) and iron supplements. Space these medications at least two hours apart from Ketograce Tablet .
  • Calcium and Vitamin D: Taking this medicine alongside calcium supplements or vitamin D analogues can significantly increase the risk of high blood calcium levels.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • High-Calcium Foods: Consuming excessive amounts of dairy products or calcium-fortified foods may increase the risk of calcium buildup in the blood.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Ketograce Tablet is used in the treatment of chronic kidney disease.
Ketograce Tablet mimics the same catabolic pathways as amino acids and works by improving the body's metabolism, thereby improving renal function.
CKD is usually caused by various conditions such as high blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, kidney stones that keep coming back, an enlarged prostate, and long-term or regular use of certain medicines such as lithium and non-steroidal anti-inflammatory drugs (NSAIDs).
CKD can be diagnosed using blood and urine tests. These tests look for high levels of certain substances in the blood and urine that show your kidneys are malfunctioning. The results of these tests can be used to determine the stage of your kidney disease.
There are usually no symptoms of kidney disease in the early stages. At a more advanced stage, symptoms can include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in your pee (urine). It may only be diagnosed if you have a blood or urine test for another reason and the results show a possible problem with your kidneys.
No, Ketograce Tablet is not same as arginine alpha-ketoglutarate. Ketograce Tablet contains alpha ketoanalogue which is a combination of different amino acids, whereas arginine alpha-ketoglutarate is a combination of alpha-ketoglutaric acid &essential amino acid arginine.
Ketograce Tablet should be swallowed as a whole with water; do not crush or chew it.
Side effects of Ketograce Tablet include increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Talk to your doctor if you experience these side effects persistently.
This medicine works best when combined with a low-protein diet prescribed by your doctor. Taking it without dietary restrictions may reduce its benefits. Talk to your doctor or pharmacist about a customised diet plan.
Taking this medicine during meals helps your body absorb and use the nutrients properly to convert waste products into essential proteins. It also helps prevent stomach discomfort.
No, it cannot cure chronic kidney disease, but it helps delay the progression of the disease and reduces the accumulation of toxic waste in your blood. Talk to your doctor to understand how this fits into your overall treatment plan.
If blood tests show high calcium levels, your doctor may reduce your dose, recommend a lower-calcium diet, or temporarily stop the medication. Always follow your doctor's guidance.
There is limited safety data regarding its use during pregnancy. Talk to your doctor or pharmacist to weigh the potential benefits against any risks before starting this medicine.
Yes. The calcium salts present in this medicine can bind to iron in the gastrointestinal tract, reducing its absorption. To minimise this interaction, take iron supplements at least 2 hours before or after Ketograce Tablet or follow the schedule recommended by your doctor or pharmacist.
While there is no direct interaction, alcohol can put extra strain on your kidneys and affect your overall hydration status. It is best to consult your doctor about safe alcohol consumption.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

Ravenbhel Pharmaceuticals (P) Ltd., 7, Baba Budha Ji Avenue, G.T. Road, Amritsar-Punjab (143001)
Other Info - KET0304

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