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  3. Ketotram Tablet 10's

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Ketotram Tablet 10's, Pack of 10 TABLETS
Ketotram Tablet 10's, Pack of 10 TABLETS
Ketotram Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Ketotram Tablet is an analgesic medicine used to relieve moderate to severe pain and inflammation. This medicine works by blocking pain signals from being transmitted to the brain and from being perceived by the brain, thus relieves body swelling and subsequent pain. Common side effects include stomach ache, nausea, vomiting, gas, and dizziness.
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Composition :

KETOROLAC-10MG + TRAMADOL-25MG

Manufacturer/Marketer :

Medley Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ketotram Tablet

Ketotram Tablet belongs to the group of painkillers and analgesics used short-term to relieve moderate to severe pain. Pain is a sensation that occurs in response to external injury, stress, infection and travels as an impulse through body cells, producing an unpleasant feeling and alerting the body to act.

Ketotram Tablet contains Ketorolac and Tramadol. Ketotram Tablet works by reducing the production of inflammatory substances (prostaglandins) and thus, relieves the body of swelling and subsequent pain. Ketotram Tablet also blocks pain-producing nerve transmitters, thereby providing pain relief. 

Take Ketotram Tablet as prescribed. Ketotram Tablet may cause certain common side effects such as stomach ache, nausea, vomiting, gas, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of Ketotram Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Ketotram Tablet may cause dizziness, so drive only if you are alert. Avoid taking alcohol with Ketotram Tablet as it might lead to increased dizziness.

Uses of Ketotram Tablet

Treatment of Pain

Directions for Use

• Ketotram Tablet can be taken with or without food, as advised by your doctor. However, avoid taking it with high-fat foods.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow the whole Ketotram Tablet with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Ketotram Tablet is an analgesic that is used as a painkiller for short-term management of moderate to severe pain. Ketotram Tablet contains Ketorolac and Tramadol. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing the levels of inflammatory substances called prostaglandins. Prostaglandins are produced at the site of injury and cause inflammation and pain. Tramadol blocks the cellular reuptake of neurotransmitters (sensation-producing substances travelling through nerves) serotonin and noradrenaline, omitting pain impulses at the spinal level. Thus, Ketotram Tablet helps relieve pain.

How Ketotram Tablet Works

Ketotram Tablet contains Ketorolac and Tramadol. Ketotram Tablet works by reducing the production of inflammatory substances (prostaglandins) and thus, relieves the body of swelling and subsequent pain. Ketotram Tablet also blocks pain-producing nerve transmitters, thereby providing pain relief.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ketotram Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink ample water throughout the day to thin mucus and keep nasal passages moist.
  • Utilize a humidifier, especially during dry seasons, to add moisture to the air.
  • Limit exposure to cigarette smoke, dust, strong odours, and other environmental pollutants.
  • Regularly use saline nasal spray to cleanse and moisturize nasal passages.
  • Practice good hand hygiene to prevent spreading germs and avoid touching your nose unnecessarily.
  • Elevate your head while sleeping to promote drainage from the sinuses.
  • Identify and avoid known allergens through allergy testing and implement measures to reduce exposure like air purifiers.
  • Inhale steam from a hot shower or bowl of water can help loosen mucus.
  • Practice relaxation techniques like yoga or meditation to manage stress which can exacerbate nasal discomfort.
  • Maintain a balanced diet rich in fruits and vegetables to support immune function.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Ketotram Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include blurred vision, shortness of breath, difficulty in speaking, severe headache, unusual tiredness, fainting and ringing in the ears. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Ketotram Tablet should not be used in case of any known allergy to either of the components or to NSAID’s/opioids in general. Ketotram Tablet is not recommended for use in case of high risk or previous history of peptic ulcer disease, bleeding disorders, heart failure, asthma, IBD or if you have had any kind of stroke (even transient ischaemic stroke). Ketotram Tablet should be used with caution in patients with a known history of substance abuse (individual or within the family), diabetes mellitus, epilepsy, kidney disease, liver disease, arterial or thrombotic disorders, cardiovascular health disorders, mental health issues, asthma, emphysema, pancreatitis, gallbladder disease, bleeding disorders, peptic ulcers, IBD/IBS, enlarged prostate, rheumatoid arthritis, dry eye syndrome, hypertension, obesity, anaemia, nasal polyps (overgrowth in the nose), stroke and any disease-causing swelling in the feet and hands. Consult your doctor before using Ketotram Tablet during pregnancy or breastfeeding as it is not recommended for use in these states. 

Drug-Drug Interactions

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KetorolacNabumetone
Critical
KetorolacIbuprofen
Critical

Drug-Drug Interactions

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KetorolacNabumetone
Critical
How does the drug interact with Ketotram Tablet:
Using Ketotram Tablet together with nabumetone may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulcers.

How to manage the interaction:
Taking Ketotram Tablet with Nabumetone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
KetorolacIbuprofen
Critical
How does the drug interact with Ketotram Tablet:
Taking Ketotram Tablet and Ibuprofen can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketotram Tablet and Ibuprofen together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
KetorolacSalsalate
Critical
How does the drug interact with Ketotram Tablet:
Using Ketotram Tablet together with salsalate may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulcers.

How to manage the interaction:
Taking Salsalate with Ketotram Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
KetorolacMefenamic acid
Critical
How does the drug interact with Ketotram Tablet:
Coadministration of Mefenamic acid with Ketotram Tablet can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Mefenamic acid with Ketotram Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
KetorolacPentoxifylline
Critical
How does the drug interact with Ketotram Tablet:
Taking Ketotram Tablet with Pentoxifylline can increase the risk of bleeding.

How to manage the interaction:
Taking Pentoxifylline with Ketotram Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness contact you doctor immediately. Do not discontinue any medications without consulting a doctor.
KetorolacEtodolac
Critical
How does the drug interact with Ketotram Tablet:
Using Ketotram Tablet together with etodolac may increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding and ulceration).

How to manage the interaction:
Taking Etodolac with Ketotram Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetorolacNaproxen
Critical
How does the drug interact with Ketotram Tablet:
Coadministration of Ketotram Tablet with Naproxen can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketotram Tablet with Naproxen together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
KetorolacCelecoxib
Critical
How does the drug interact with Ketotram Tablet:
Taking Ketotram Tablet with Celecoxib can increase the risk of side effects such as gastrointestinal bleeding and ulcers.

How to manage the interaction:
Taking Celecoxib with Ketotram Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
KetorolacCidofovir
Critical
How does the drug interact with Ketotram Tablet:
Co-administration of Cidofovir with Ketotram Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Ketotram Tablet with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
KetorolacTolmetin
Critical
How does the drug interact with Ketotram Tablet:
Using Ketotram Tablet together with tolmetin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketotram Tablet with Tolmetin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Stay hydrated by drinking plenty of water.
  • Invest in a balanced diet. Load up on lean meats, fruits, green leafy vegetables, nuts, oily fish etc. Limit your intake of sweets and sugars as these can worsen inflammation. 
  • Cut back on alcohol as this can have an adverse effect on pain states as well as the quality of your sleep.
  • Try meditation and deep breathing to reduce overall stress and pain. 
  • Stop smoking as smoking is known to worsen pain conditions. 
  • Engage in mild physical exercise daily and keep your body active. 

Habit Forming

Yes

Therapeutic Class

ANALGESICS

Ketotram Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are advised not to take alcohol with Ketotram Tablet as it can make you dizzier. Please consult your doctor if you have any concerns.

bannner image

Pregnancy

Caution

Ketotram Tablet is not recommended for use during pregnancy unless absolutely indicated. Please consult your doctor if you have any concerns.

bannner image

Breast Feeding

Caution

Ketotram Tablet is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

bannner image

Driving

Caution

Ketotram Tablet may cause dizziness and drowsiness, which may affect your ability to drive. Therefore, drive only if you are alert.

bannner image

Liver

Caution

Exercise caution before using Ketotram Tablet in case of established liver disease. Please consult your doctor to address any concerns.

bannner image

Kidney

Caution

Exercise caution before using Ketotram Tablet in case of kidney problems. Please consult your doctor to address any concerns.

bannner image

Children

Unsafe

Ketotram Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Have a query?

FAQs

Ketotram Tablet belongs to the group of painkillers and analgesics used short-term to relieve moderate to severe pain.

Ketotram Tablet works by reducing the levels of prostaglandins (inflammatory markers), blocking the impulses of pain, relieving the body of inflammation and reducing the sensation of pain.

Ketotram Tablet should be used with caution in those suffering from asthma. Consult your doctor before use if you have asthma.

While Ketotram Tablet is safe for treating pain, Ketotram Tablet is not meant for long-term use because it can damage the kidneys and/or cause internal bleeding if used for longer durations.

No, Ketotram Tablet is not indicated as a painkiller during labour and delivery as it may cause uterine bleeding.

Ketotram Tablet is not indicated to treat headaches due to migraines. It is best to get your headache checked by a professional. Please consult your doctor in case of any concerns.

Yes, Ketotram Tablet can be used for toothache and to relieve pain after a dental procedure if prescribed by the doctor. Always follow the doctor’s instructions while using Ketotram Tablet .

Consult the doctor before using Ketotram Tablet with seizure medication as it may affect serotonin levels and can increase the risk of a serious condition called serotonin syndrome.

The common side effects of Ketotram Tablet include stomach ache, nausea, vomiting, gas, and dizziness. In most cases, these side effects are mild and temporary and will go away on their own over time. However, if these symptoms persist or worsen, it's important to consult with your doctor for further guidance and support.

Country of origin

INDIA

Manufacturer/Marketer address

Medley House, D2, M.I.D.C. Area, Andheri (East), Mumbai-400 093, INDIA
Other Info - KET0341

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:27 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019645s019lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3d88cbe6-5230-47aa-80af-0c41283d1f00&type=display
  3. https://www.mayoclinic.org/drugs-supplements/ketorolac-oral-route-injection-route/description/drg-20066882
  4. https://www.uofmhealth.org/health-library/d00273a1#:~:text=Ketorolac%20should%20not%20be%20used,moisture%2C%20heat%2C%20and%20light.
  5. https://www.webmd.com/drugs/2/drug-3919/ketorolac-oral/details
  6. https://clinicaltrials.gov/ct2/show/NCT03767036
  7. https://www.medicines.org.uk/emc/files/pil.7123.pdf
  8. https://www.who.int/medicines/areas/quality_safety/6_1_Update.pdf
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811866/
  10. https://pubmed.ncbi.nlm.nih.gov/9190321/
  11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888666/
  12. https://pubmed.ncbi.nlm.nih.gov/16539862/
  13. https://americanaddictioncenters.org/tramadol-abuse/withdrawal
  14. https://www.drugs.com/food-interactions/tramadol.html
  15. https://www.nhs.uk/medicines/tramadol/

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