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Klarim Tablet is used to treat bacterial infections. It contains Clarithromycin, which inhibits the growth of bacteria. It may cause some common side effects, such as nausea, diarrhoea, vomiting, loss of appetite, bloating, indigestion, headaches and difficulty sleeping. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Morepen Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Klarim Tablet

Klarim Tablet is a prescription medicine used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria in the body, making it highly effective for respiratory tract infections, throat infections, and skin issues. Doctors frequently prescribe this antibiotic to help clear up these temporary infections quickly and completely.

To get the best results, you must take Klarim Tablet at regular intervals and complete the entire course prescribed by your doctor, even if you start feeling better. You can take this oral medication with or without food, though taking it with a meal can help prevent an upset stomach. While recovering, drinking plenty of water and getting adequate rest will support your immune system's healing process.

While taking Klarim Tablet , you may experience mild stomach irritation, changes in taste, or nausea. These symptoms are usually temporary, but you must contact your doctor immediately if you develop serious side effects like severe, watery diarrhoea, yellowing of the eyes or skin, or an irregular heartbeat.

Do not take this if you have a history of severe allergic reactions to macrolide antibiotics or if you suffer from certain heart rhythm disorders. It is also important to talk to your doctor before starting Klarim Tablet if you have a history of liver disease, kidney problems, or myasthenia gravis.

Certain medications, including some cholesterol-lowering drugs and blood thinners, can interact poorly with Klarim Tablet , so you should avoid drinking alcohol during treatment to prevent liver strain. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to ensure this medicine is safe for you.

Uses of Klarim Tablet

Klarim Tablet is a macrolide antibiotic used to treat a variety of bacterial infections. It works by stopping the growth and spread of bacteria, helping your body fight off infection and recover more effectively.

  • Respiratory tract infections: Helps treat pneumonia, bronchitis, and sinus infections by clearing the bacteria causing the swelling and congestion in your airways.
  • Throat and tonsil infections: Resolves strep throat and tonsillitis by eliminating the bacterial infection, relieving painful swallowing and soreness.
  • Skin and soft tissue infections: Clears up uncomplicated skin infections by stopping bacterial growth in the skin layers, reducing redness, swelling, and pain.
  • Stomach ulcers (H. pylori infection): Used in combination with other medicines to eliminate the specific bacteria that cause painful ulcers in the stomach lining.
  • Mycobacterial infections: Helps prevent and treat serious, widespread bacterial infections in people with compromised immune systems.
     

Key Benefits

Klarim Tablet helps eliminate bacterial infections at their source, allowing symptoms to improve and supporting a faster recovery.

  • Effective bacterial infection control: Directly targets and stops the growth of susceptible bacteria, helping your body overcome infection.
  • Relief from infection symptoms: Reduces symptoms such as fever, sore throat, cough, chest congestion, fatigue, and discomfort as the infection clears.
  • Supports faster recovery: By treating the underlying cause of infection, it helps patients return to their normal activities sooner.
  • Convenient dosing schedule: Its long-lasting action often allows for a simpler dosing routine compared with some other antibiotics.
  • Helps treat stomach ulcer infections: When combined with other medications, it can successfully eradicate Helicobacter pylori, promoting ulcer healing and reducing the risk of recurrence.
  • Reduces the risk of complications: Prompt treatment of bacterial infections may help prevent the infection from spreading or causing more serious health problems.
  • Helps prevent antibiotic resistance: Completing the full prescribed course helps ensure the infection is fully cleared and reduces the likelihood of bacterial resistance developing.
     
Side effects of Klarim Tablet
  • Drink plenty of fluids and consider oral rehydration solutions.
  • Eat bland, easily digestible foods like bananas, rice, toast, and applesauce.
  • Avoid trigger foods like greasy, spicy, fatty, acidic, and caffeinated foods.
  • Gradually reintroduce fiber-rich foods as symptoms improve.
  • Get adequate sleep and rest.
  • Practice relaxation techniques to manage stress.
  • Maintain regular bowel habits.
  • Avoid overexertion and take breaks when needed.
  • Consult a doctor if your gastrointestinal symptoms are severe, persistent, or accompanied by fever, bloody stools, dehydration, or last for more than a few days.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

To ensure the medicine works effectively and helps clear your infection completely, take Klarim Tablet exactly as prescribed by your healthcare provider.

  • Swallow the tablet whole with a glass of water.
  • Do not crush, chew, or break the tablet, as this can alter how the medicine is absorbed in your body.
  • If you are taking the liquid suspension, shake the bottle well before each use.
  • Measure the liquid dose carefully using the provided measuring device, oral syringe, or measuring cup rather than a household spoon.
  • You can take this medicine with or without food.
  • Taking Klarim Tablet with food may help reduce stomach upset.
  • Take the medication at the same time each day to maintain a steady level of the drug in your body.
  • Complete the full course of treatment, even if you start feeling better before the medicine is finished.
  • Do not skip doses or stop taking the medication without consulting your doctor.
  • If you miss a dose, take it as soon as you remember unless it is nearly time for your next scheduled dose.
  • Do not take two doses at the same time.
  • Always follow your doctor's exact instructions regarding dosage and length of treatment.
     

How Klarim Tablet Works

Klarim Tablet contains clarithromycin, a macrolide antibiotic that helps treat bacterial infections in different parts of the body. Clarithromycin works by interfering with the bacteria's ability to produce essential proteins that they need to grow, multiply, and survive. By blocking the bacterial protein-making process, it prevents the bacteria from reproducing and spreading within the body. Once the bacteria can no longer multiply, your body's natural immune system can more effectively identify, attack, and eliminate the remaining bacteria from the infection site. Together, these actions help clear bacterial infections, relieve symptoms, and support the body's recovery process.
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Alcohol

Consult your doctor

Limited information is available. Keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

Klarim Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Klarim Tablet ; your doctor will decide whether Klarim Tablet can be taken by breastfeeding mothers or not.

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Driving

Consult your doctor

Not enough scientific data available, hence it is advised to consult your doctor.

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Liver

Caution

Klarim Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Klarim Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Klarim Tablet can be given safely to children above 6 months of age, with the dose to be adjusted and recommended by a child specialist only.

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Heart

Consult your doctor

Caution should be exercised while taking Klarim Tablet in patients with heart disease. Inform your physician on priority if you/your child have chest discomfort, palpitations or irregular heartbeat. Your physician may adjust the dose of the medicine based on your health condition.

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Geriatrics

Safe if prescribed

Klarim Tablet is safe for use in geriatric patients if recommended by the physician. Your doctor will decide the dose and duration of medicine.<br />

What if I have taken an overdose of Klarim Tablet

Do not take more than the prescribed dose of Klarim Tablet as it may cause overdose. The symptoms of overdose include diarrhoea, vomiting, nausea and stomach pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay Hydrated: Drink plenty of fluids, such as water, herbal teas, or clear broths. Hydration helps thin respiratory mucus and supports your body as it fights off infection.
  • Protect Your Gut: Consider taking a probiotic supplement or eating fermented foods like yogurt with live cultures. Since Klarim Tablet can temporarily disrupt your gut bacteria, probiotics can help maintain a healthy digestive balance (just space them a few hours apart from your antibiotic dose).
  • Get Plenty of Rest: Avoid strenuous physical activities while recovering. Resting allows your immune system to direct its energy toward clearing the infection.
  • Avoid Acidic Foods if Stomach is Upset: If you experience nausea or stomach irritation, avoid highly spicy, fatty, or acidic foods, which can worsen digestive discomfort.
     
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How Soon It Starts Working

The time required for Klarim Tablet to start to work: Klarim Tablet ideally shows its action within 2 to 3 hours after administration.

The time for which the effects of Klarim Tablet last: The effect of Klarim Tablet lasts for 36 hours.

What if you forget to take Klarim Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular schedule.

Storage

Store Klarim Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original container to protect them from moisture and light.

Drug Warnings

  • Finish the entire prescription: Always complete the full course of therapy, even if you feel completely recovered after a few days, to prevent the bacteria from returning and becoming resistant.
  • Watch for severe diarrhoea: If you develop severe, watery, or bloody diarrhoea during or up to several months after treatment, contact your doctor immediately; do not take anti-diarrhoea medications without medical advice.
  • Check for drug interactions: Provide your doctor and pharmacist with a complete list of all medications, vitamins, and herbal supplements you are currently taking, as Klarim Tablet interacts with many common drugs.
  • Avoid grapefruit products: Do not consume grapefruit or grapefruit juice while taking this medication, as it can raise the levels of Klarim Tablet in your blood and increase the risk of side effects.
  • Monitor liver health: If you notice dark urine, pale stools, persistent nausea, or yellowing of the skin or eyes, stop taking the medication and seek medical attention immediately.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Klarim Tablet can interact with a number of medications, potentially increasing side effects or altering how the medicines work. Inform your healthcare provider about all prescription medicines, over-the-counter products, and supplements you are taking before starting treatment.

  • Statins (such as atorvastatin or simvastatin): Combining these with Klarim Tablet can significantly increase the risk of severe muscle pain and muscle breakdown.
  • Blood thinners (such as warfarin): Klarim Tablet can increase the effects of blood thinners, raising your risk of bleeding.
  • Heart rhythm medications (such as amiodarone or quinidine): Taking these together can increase the risk of dangerous, irregular heart rhythms.
  • Colchicine: Klarim Tablet can dangerously increase the levels of colchicine in your body, potentially leading to severe toxicity.

Drug-Food Interactions

Certain foods and beverages may affect how Klarim Tablet is processed by your body or increase the likelihood of side effects.

  • Grapefruit and Grapefruit Juice: Can slow down how your body processes Klarim Tablet , leading to higher drug levels in your blood and an increased risk of side effects.
  • Alcohol: While alcohol does not directly stop the antibiotic from working, it can increase side effects like dizziness and put extra strain on your liver during recovery.

Drug-Disease Interactions

Some medical conditions may affect the safety and effectiveness of Klarim Tablet and may require closer monitoring during treatment.

  • Heart Conditions (QT Prolongation): Do not take this medicine if you have a history of certain irregular heart rhythms or long QT syndrome, as it can worsen these conditions.
  • Liver or Kidney Disease: People with severe liver or kidney impairment may require a lower dose or closer monitoring, as these organs are responsible for clearing the medicine from your body.
  • Myasthenia Gravis: This antibiotic may worsen muscle weakness symptoms in individuals with this neuromuscular condition.
     

Drug-Drug Interactions

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How does the drug interact with Klarim Tablet:
Taking Klarim Tablet with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Klarim Tablet and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Klarim Tablet:
Combining Klarim Tablet with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Klarim Tablet and Thioridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Klarim Tablet:
When Methylergometrine is taken with Klarim Tablet, the amount of Methylergometrine in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Klarim Tablet with Methylergometrine is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Klarim Tablet:
Co-administration of Klarim Tablet and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Klarim Tablet and Simvastatin together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
ClarithromycinAstemizole
Critical
How does the drug interact with Klarim Tablet:
When Astemizole is taken with Klarim Tablet, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Klarim Tablet with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinSaquinavir
Critical
How does the drug interact with Klarim Tablet:
When Klarim Tablet is taken with Saquinavir, increases the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Klarim Tablet and Saquinavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Klarim Tablet:
Combining Klarim Tablet with Pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
Co-administration of Klarim Tablet and Pimozide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision or nausea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinDroperidol
Critical
How does the drug interact with Klarim Tablet:
Co-administration of Droperidol with Klarim Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Klarim Tablet with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Klarim Tablet:
Co-administration of Klarim Tablet and Sparfloxacin may result in an increased risk of QT interval prolongation.

How to manage the interaction:
Co-administration of Sertraline and Desvenlafaxine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinErgotamine
Critical
How does the drug interact with Klarim Tablet:
When Ergotamine is taken with Klarim Tablet, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Klarim Tablet with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may delay the gastrointestinal absorption of Klarim Tablet. Avoid grapefruit juice while on treatment with Klarim Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Klarim Tablet is used to treat bacterial infections, including chest infections, skin infections, and ear infections. Besides this, Klarim Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.
Klarim Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Klarim Tablet helps in the prevention of infections.
You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Klarim Tablet . Avoid taking any other antibiotics containing Klarim Tablet unless your doctor has prescribed you.
After taking antibiotics such as Klarim Tablet , some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.
Klarim Tablet treats only bacterial infections. It will not work for viral infections (such as the common cold, flu).
No, Klarim Tablet is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor's advice only.
Side effects are rare with Klarim Tablet and do not usually last long. They will get better after a day or two. If any side effects persist, reach out to the doctor immediately.
No, Klarim Tablet should not be stopped even if you feel better, as it is an antibiotic medication and completing the full course is very necessary; otherwise, the infection might reappear in a more severe form.
It is highly recommended to avoid alcohol while taking Klarim Tablet . Alcohol can worsen side effects like dizziness and nausea, and it can dehydrate your body, making it harder for your immune system to fight off the infection. Talk to your doctor or pharmacist if you have concerns.
Most people start to feel better within 24 to 48 hours of starting Klarim Tablet . However, even if your symptoms disappear, you must complete the full prescribed course to ensure the infection is completely cleared. If you do not feel better after a few days, talk to your doctor.
Grapefruit and grapefruit juice can block the enzymes that break down Klarim Tablet in your body. This can cause the drug to build up to unsafe levels in your system, increasing your risk of severe side effects. Talk to your doctor for further guidance.
A temporary metallic or altered taste in your mouth is a common and harmless side effect of Klarim Tablet . It typically goes away once you finish your course of treatment. Chewing sugar-free gum or sucking on hard candies may help manage this symptom. If it becomes severe, talk to your doctor.
Klarim Tablet is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits outweigh the potential risks. Some studies suggest it may affect the developing baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor.
Yes, taking probiotics can help restore the healthy bacteria in your gut that may be disrupted by Klarim Tablet . To prevent the antibiotic from killing the active probiotics, space them out by taking your probiotic at least two hours before or after your antibiotic dose. Talk to your doctor or pharmacist for recommendations.
Severe, watery, or bloody diarrhoea can be a sign of a serious secondary infection in your gut. Do not take any anti-diarrhoea medications, as they can make the condition worse. Stop taking the medicine if safe, and contact your doctor immediately.

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Country of origin

India

Manufacturer/Marketer address

409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi - 110 001.
Other Info - KLA0043
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