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compositionComposition:LACOSAMIDE-10MG
prescriptionPrescription Medicine
LACONEXT INJECTION 20ML

LACONEXT INJECTION is an anticonvulsant medicine used in the treatment of partial-onset seizures and generalised tonic-clonic seizures. It contains lacosamide, which works by decreasing the disorganised electrical activity in the brain and thereby helps treat seizures. Common side effects include nausea, vomiting, diarrhoea, dry mouth and dizziness. Let your doctor know if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LACOSAMIDE-10MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About LACONEXT INJECTION

LACONEXT INJECTION is an anticonvulsant medicine used in the treatment of partial-onset seizures and generalised tonic-clonic seizures.

LACONEXT INJECTION contains lacosamide, which treats seizures by decreasing disorganised electrical activity in the brain.

In some cases, LACONEXT INJECTION may cause side effects like nausea, vomiting, diarrhoea, dry mouth and dizziness. Most of these side effects of LACONEXT INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Consult your doctor if you are pregnant or breastfeeding. Inform your doctor about your medical history and other medications you are currently taking in order to rule out any potential negative effects.

Uses of LACONEXT INJECTION

LACONEXT INJECTION is used in the treatment of focal (partial) seizures. The detailed uses of LACONEXT INJECTION are as follows:

  • Partial-onset (focal) seizures: Treats partial-onset (focal) seizures in both adults and children, helping to reduce abnormal brain activity.
  • Generalised tonic-clonic seizures: Controls generalised tonic-clonic seizures, which cause loss of consciousness along with muscle stiffness and jerking movements.

Key Benefits

  • LACONEXT INJECTION effectively manages seizures affecting only one part of the brain in adults and children (1 month and older) who cannot take oral medicines.
  • It is used along with other medicines to control full-body seizures (grand mal seizures) in adults and children (4 years and older) who are unable to take oral treatment.
  • LACONEXT INJECTION provides an alternative for patients who need seizure control but cannot swallow or tolerate oral medications.
  • It decreases abnormal electrical signals in the brain, reducing seizure frequency and severity.
  • LACONEXT INJECTION helps prevent seizure-related complications, injuries, and interruptions to daily living.
Side effects of Laconext Injection 20ml
  • Wear an eye patch or opaque contact lens or lens applied to glasses to block the vision of one eye to minimize double vision.
  • Use prisms (lenses applied to glasses) to correct double vision due to small misalignments.
  • Try doing some eye exercises such as moving the target towards nose slowly or focussing on a detailed target like thin stick or small text in a magazine.
  • If you feel eye pain, develop bulging eyes, have weakness, headache or double vision, consult a doctor immediately.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • LACONEXT INJECTION will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How LACONEXT INJECTION Works

LACONEXT INJECTION contains lacosamide, which treats seizures by decreasing disorganised electrical activity in the brain.
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Alcohol

Unsafe

Consuming alcohol with LACONEXT INJECTION is not advisable as it may cause unpleasant side effects.

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Pregnancy

Caution

LACONEXT INJECTION should not be used during pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing LACONEXT INJECTION.

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Breast Feeding

Caution

LACONEXT INJECTION should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing LACONEXT INJECTION.

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Driving

Unsafe

LACONEXT INJECTION may cause a reduction in mental awareness; thus, avoid operating machinery or driving.

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Liver

Caution

Inform your doctor before receiving the LACONEXT INJECTION if you have a liver impairment or a history of liver disease. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Inform your doctor before receiving the LACONEXT INJECTION if you have kidney impairment or a history of kidney disease. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

LACONEXT INJECTION can be used for children one month and older.

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Heart

Caution

LACONEXT INJECTION may affect heart rhythm, so it is used cautiously in patients with cardiac conditions. Doctors often recommend ECG monitoring to detect potential arrhythmias before and during treatment.

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Geriatrics

Caution

Geriatric patients can receive LACONEXT INJECTION, but it may be more sensitive to side effects like dizziness, coordination issues, or heart rhythm changes. Close monitoring and dose adjustments are often recommended to ensure safety.

What if I have taken an overdose of LACONEXT INJECTION

LACONEXT INJECTION is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. An overdose of LACONEXT INJECTION may cause seizures and coma. Your doctor will initiate necessary measures when an overdose is suspected.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and sleep well.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Have a query?

How Soon It Starts Working

The time required for LACONEXT INJECTION to start to work: LACONEXT INJECTION ideally shows its action within 1 to 4 hours after administration.

The time for which the effects of LACONEXT INJECTION last: The duration of action for LACONEXT INJECTION is unknown.

What if you forget to take LACONEXT INJECTION

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take LACONEXT INJECTION if you are allergic to any of its contents.
  • Inform your doctor before taking LACONEXT INJECTION if you have depression, heart problems, kidney and liver problems, have low levels of sodium in your blood, or are taking medicines that could lower the levels of sodium in the blood.
  • Inform your doctor if you are pregnant or suspect pregnancy or if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing LACONEXT INJECTION.
  • An ECG is recommended before and after titration to maintain steady-state maintenance in patients.
  • To reduce the risk of increased seizure frequency, LACONEXT INJECTION should be progressively discontinued.
  • Consult your doctor immediately if you experience suicidal tendencies.
  • LACONEXT INJECTION may cause a reduction in mental awareness; hence, do not drive, operate complex machinery, or engage in other hazardous activities.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: LACONEXT INJECTION may interact with HIV medications (atazanavir, saquinavir), opioid medications (buprenorphine), anticancer medications (ceritinib), prevent nausea and vomiting caused by cancer chemotherapy (dolasetron), anaesthetic medications (ketamine), used to treat multiple sclerosis (ponesimod, siponimod), medicines used to treat episodes of muscle weakness (sodium oxybate).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: LACONEXT INJECTION should be used with caution in patients with depression, renal or hepatic impairment and heart conditions.

LacosamideBuprenorphine
Severe
LacosamideSodium oxybate
Severe

Drug-Drug Interactions

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LacosamideBuprenorphine
Severe
How does the drug interact with Laconext Injection 20ml:
When Buprenorphine is used with Laconext Injection 20ml, it may lead to side effects such as respiratory difficulties, and unconsciousness.

How to manage the interaction:
Although the combination of Buprenorphine with Laconext Injection 20ml can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You are advised to avoid driving or operating hazardous machinery. Do not discontinue any medications without consulting a doctor.
LacosamideSodium oxybate
Severe
How does the drug interact with Laconext Injection 20ml:
Co-administration of Laconext Injection 20ml with Sodium oxybate can increase side effects.

How to manage the interaction:
Although taking Laconext Injection 20ml and Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience any symptoms such as drowsiness, dizziness, lightheadedness, confusion, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination. Do not discontinue any medications without a doctor's advice.
LacosamideKetamine
Severe
How does the drug interact with Laconext Injection 20ml:
When Ketamine and Laconext Injection 20ml are combined, may increase the risk of side effects.

How to manage the interaction:
Although taking Laconext Injection 20ml and Ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as dizziness, drowsiness, confusion, breathing difficulty, impairment in thinking, judgment, and motor coordination, consult the doctor. Do not discontinue any medications without a doctor's advice.
LacosamideDolasetron
Severe
How does the drug interact with Laconext Injection 20ml:
Co-administration of Laconext Injection 20ml and Dolasetron can increase the risk of serious irregularities in heart rhythm.

How to manage the interaction:
Although taking Laconext Injection 20ml and Dolasetron together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, dizziness, fainting, or an irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
LacosamideEsketamine
Severe
How does the drug interact with Laconext Injection 20ml:
When used with Laconext Injection 20ml, Esketamine may increase the risk of side effects.

How to manage the interaction:
Although taking Laconext Injection 20ml and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not discontinue any medications without a doctor's advice.
LacosamideSaquinavir
Severe
How does the drug interact with Laconext Injection 20ml:
Co-administration of Laconext Injection 20ml along with Saquinavir can raise the chance of an abnormal heart rhythm.

How to manage the interaction:
Although taking Laconext Injection 20ml and Saquinavir together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, fainting, a slow heartbeat, or dizziness, consult a doctor. Do not discontinue any medications without a doctor's advice.
LacosamideCeritinib
Severe
How does the drug interact with Laconext Injection 20ml:
Taking Ceritinib together with Laconext Injection 20ml can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Laconext Injection 20ml and Ceritinib together can result in an interaction, it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty. Do not discontinue any medications without consulting a doctor.
LacosamideIdelalisib
Severe
How does the drug interact with Laconext Injection 20ml:
When Laconext Injection 20ml is taken along with Idelalisib, it might enhance the amount or action of Laconext Injection 20ml, which may increase the risk of side effects.

How to manage the interaction:
Although taking Laconext Injection 20ml and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

LACONEXT INJECTION belongs to the class of anticonvulsants used to treat partial onset seizures (seizures that affect only one portion of the brain) in adults and children one month or older who cannot take oral treatments. LACONEXT INJECTION is also used in conjunction with other medications to manage primary generalised tonic-clonic seizures.

LACONEXT INJECTION contains lacosamide, which treats seizures by decreasing disorganised electrical activity in the brain.

Coordination and walking issues normally improve within a few weeks. Inform your service provider if the problems persist.

LACONEXT INJECTION should be used with caution in patients who are taking drugs that influence cardiac conduction, such as sodium channel blockers, beta-blockers, calcium channel blockers, potassium channel blockers, and medications that lengthen the PR interval.

Your doctor can identify a seizure after hearing about your experience or the signs noted by others. Your doctor may recommend testing based on your symptoms and medical history. Brain imaging scans, blood tests, or a spinal tap may be used to determine the cause of your seizures.

In people with cardiac rhythm and conduction abnormalities, use LACONEXT INJECTION with caution. In patients with underlying proarrhythmic disorders or who are taking concomitant drugs that influence cardiac conduction, an ECG should be obtained before and after titration for steady-state maintenance; these patients should be regularly monitored.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - LAC0327

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