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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lesuride MPS Tablet is used to treat gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), and dyspepsia (indigestion). Additionally, it is also used to treat psychotic disorders like somatic symptom disorders and chronic schizophrenia with negative symptoms. It contains Levosulpiride, which helps prevent stomach acid from flowing back into the food pipe, enhances gut motility to relieve indigestion, and blocks the action of chemical receptors (dopamine) in the brain to improve mood, behaviour, and thoughts. Common side effects of Lesuride MPS Tablet include dizziness, sleepiness, weakness, and vertigo (spinning sensation).

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Composition :

LEVOSULPIRIDE-25MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lesuride MPS Tablet

Lesuride MPS Tablet is used to treat gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), and dyspepsia (indigestion). Additionally, Lesuride MPS Tablet is also used to treat psychotic disorders like somatic symptom disorders and chronic schizophrenia with negative symptoms.

Lesuride MPS Tablet contains Levosulpiride, which increases the pressure in the lower oesophageal sphincter, helping to prevent stomach acid from flowing back into the oesophagus (food pipe). It enhances gut motility without disrupting its rhythm, thereby relieving indigestion. Additionally, Lesuride MPS Tablet blocks the action of chemical receptors (dopamine) in the brain, helping to improve mood, behaviour, and thoughts.

Take Lesuride MPS Tablet exactly as advised by your doctor. Swallow it whole with a glass of water, and do not crush or chew it. Lesuride MPS Tablet may sometimes cause common side effects such as dizziness, sleepiness, weakness, and vertigo (spinning sensation). Please talk to your doctor if you experience these side effects persistently.

Do not take Lesuride MPS Tablet if you are pregnant or breastfeeding. It is not recommended for children, as its safety has not been established. Keep your doctor informed about your health condition and any other medicines you are taking to avoid potential side effects or interactions.

Uses of Lesuride MPS Tablet

Lesuride MPS Tablet is used in the treatment of gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), dyspepsia (indigestion), somatic symptom disorder (SSD), and schizophrenia. The detailed uses of Lesuride MPS Tablet are as follows:

  • Treatment of GERD: Lesuride MPS Tablet is used to reduce acid reflux in GERD.
  • Treatment of IBS: Lesuride MPS Tablet helps alleviate IBS symptoms such as abdominal pain and irregular bowel habits.
  • Treatment of dyspepsia: Lesuride MPS Tablet helps relieve indigestion, bloating, and discomfort.
  • Treatment of SSD: Lesuride MPS Tablet helps reduce symptoms of SSD, such as excessive thoughts and anxiety about physical health.
  • Treatment of schizophrenia: Lesuride MPS Tablet is used to manage symptoms of schizophrenia, including hallucinations and delusions.

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Directions for Use

  • Lesuride MPS Tablet should be taken 30 minutes before food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Lesuride MPS Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Lesuride MPS Tablet offers the following medicinal benefits:

For gastroesophageal reflux disease (GERD):

  • Increases the pressure in the lower oesophageal sphincter to reduce acid reflux.
  • Helps relieve heartburn and regurgitation.

For irritable bowel syndrome (IBS):

  • Improves gut motility and coordination.
  • Reduces abdominal pain, bloating, and bowel irregularities.

For dyspepsia (indigestion):

  • Enhances stomach emptying.
  • Relieves indigestion, fullness, and discomfort.

For somatic symptom disorder (SSD):

  • Reduces excessive anxiety and distress about physical symptoms.
  • Helps regulate abnormal thought patterns and emotional responses.

For schizophrenia:

  • Blocks the brain chemical (dopamine) activity to reduce negative symptoms of schizophrenia.
  • Helps improve mood, behaviour, social interaction, and overall daily functioning.

How Lesuride MPS Tablet Works

Lesuride MPS Tablet contains Levosulpiride, which belongs to a group of medicines called 'prokinetics and antipsychotics.' It works by increasing the pressure in the lower oesophageal sphincter, helping to prevent stomach acid from flowing back into the oesophagus (food pipe) and thereby managing gastroesophageal reflux disease. It also enhances gut motility without disrupting its rhythm, which helps relieve indigestion and improve symptoms of irritable bowel syndrome. Additionally, Lesuride MPS Tablet works by blocking the action of chemical receptors (dopamine) in the brain, helping to improve mood, behaviour, and thoughts in psychotic disorders.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • To improve liver health and aid in the removal of toxins, drink lots of water.
  • Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
  • Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
  • You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.

What if I have taken an overdose of Lesuride MPS Tablet

Do not take more than the prescribed dose of Lesuride MPS Tablet , as it may cause adverse effects. If you suspect you have taken an overdose or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not take Lesuride MPS Tablet if you are allergic to any of its ingredients or if you have mania, epilepsy, high blood pressure, or breast cancer.
  • Inform your doctor before taking Lesuride MPS Tablet if you have/had gastrointestinal bleeding, blockage/perforations, dementia, heart problems, or blood clot problems.
  • Let your doctor know if you are taking any other neuroleptic medicines.
  • Do not take Lesuride MPS Tablet if you are pregnant or breastfeeding.
  • Lesuride MPS Tablet is not recommended for children, as its safety has not been established.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

For gastrointestinal disorders:

  • Eat smaller meals more often.
  • Avoid smoking, alcohol, and trigger foods (spicy, fatty, chocolate, citrus, tomato, onion, garlic, tea, soda).
  • Avoid lying down immediately after eating.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight through regular exercise.
  • Practice relaxation techniques like yoga or meditation to reduce stress.
  • Avoid sitting continuously, as it may trigger acidity.
  • Take short breaks by doing brisk walking or stretching.

For psychiatric disorders:

  • Maintain a healthy diet and exercise regularly.
  • Regularly attend therapy or counselling sessions.
  • Practice meditation and yoga to lower stress and anxiety.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Lesuride MPS Tablet to prevent unpleasant side effects.

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Pregnancy

Unsafe

Avoid taking Lesuride MPS Tablet if you are pregnant. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Lesuride MPS Tablet . Consult your doctor if you have any concerns.

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Driving

Caution

Lesuride MPS Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Consult your doctor before taking Lesuride MPS Tablet if you have a liver impairment or liver problems.

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Kidney

Caution

Consult your doctor before taking Lesuride MPS Tablet if you have kidney impairment or kidney problems.

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Children

Unsafe

Lesuride MPS Tablet is not recommended for children, as its safety and effectiveness have not been established.

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Heart

Unsafe

Lesuride MPS Tablet is contraindicated in cardiac patients due to serious adverse effects. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Lesuride MPS Tablet should be used with extreme caution in elderly patients due to an increased risk of side effects. It is important to consult a healthcare professional before use.

FAQs

Lesuride MPS Tablet is used to treat gastro-oesophageal reflux disease (GERD), irritable bowel syndrome (IBS), dyspepsia (indigestion), somatic symptom disorder, and schizophrenia.

Lesuride MPS Tablet increases the pressure in the lower oesophageal sphincter, thereby preventing the backflow of food and acid from the stomach into the mouth. This helps in treating gastro-oesophageal acid reflux.

Lesuride MPS Tablet increases gut motility by enhancing the strength of contractions without disrupting their rhythm, thereby helping in treating indigestion.

Do not discontinue Lesuride MPS Tablet without consulting your doctor. To treat your condition effectively, continue taking Lesuride MPS Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lesuride MPS Tablet .

Lesuride MPS Tablet may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly. Consult your doctor if you have any concerns.

To prevent acidity, avoid lying down immediately after meals. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This prevents acid reflux.

Lesuride MPS Tablet helps block the action of chemical receptors (dopamine) in the brain, thereby helps in improving mood, behaviour and thoughts

Lesuride MPS Tablet , commonly used as an antipsychotic, also has prokinetic properties that stimulate gastrointestinal motility, making it effective in treating various stomach disorders. It regulates stomach contractions to reduce bloating, nausea, and discomfort in functional dyspepsia, alleviates acid reflux symptoms by improving gastric emptying and motility in gastroesophageal reflux disease (GERD), and manages symptoms like abdominal pain, bloating, and bowel changes by modulating gut motility and sensitivity in irritable bowel syndrome (IBS).

Use Lesuride MPS Tablet only if prescribed by your doctor after assessing your condition. Do not take it unless your doctor has determined it's appropriate for you. Lesuride MPS Tablet can help relieve symptoms of functional dyspepsia, gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), delayed gastric emptying, and Schizophrenia.

Before taking Lesuride MPS Tablet , inform your doctor about your complete medical history, including heart, kidney, liver, and thyroid problems, diabetes, glaucoma, prostate issues, and allergies. Also, share your ongoing medications, including prescription drugs, over-the-counter meds, herbal supplements, and vitamins. Additionally, mention if you're pregnant or breastfeeding (if applicable). This will help your doctor determine if Levosulpiride is safe and suitable for you.

Lesuride MPS Tablet is a medication that belongs to the class of drugs known as prokinetics and antipsychotics. It is used to treat various gastrointestinal disorders. Additionally, Lesuride MPS Tablet has antipsychotic properties, which are not related to its gastrointestinal effects. Remember, Lesuride MPS Tablet should only be taken under the guidance of a healthcare professional.

Lesuride MPS Tablet may not be suitable for everyone, especially those with certain medical conditions or taking specific medications. This includes people with hypersensitivity, thyroid problems, cardiovascular disease, kidney or liver impairment, and those taking antipsychotics, antidepressants, or other drugs. It's important to consult a healthcare provider to ensure safe usage.

Lesuride MPS Tablet can cause dry mouth in some individuals. If you experience dry mouth, stay hydrated by drinking plenty of water, chew sugar-free gum or suck on sugar-free candy to stimulate saliva production, and avoid alcohol and caffeine. In most cases, dry mouth is a temporary side effect that fades away with time. However, if it persists or becomes bothersome, consult your healthcare provider for further guidance and support.

Lesuride MPS Tablet can cause diarrhea in some cases, in some individuals. Gastrointestinal side effects like diarrhea, abdominal pain, and nausea are possible with Levosulpiride, especially when first starting the medication or after a dose increase. However, in most cases, these side effects are mild and temporary. If you experience severe, persistent, or bloody diarrhea, consult your healthcare provider promptly.

Store in a cool and dry place away from sunlight. Keep out of reach and sight of children.

Yes, Lesuride MPS Tablet is generally safe when used as prescribed by a healthcare professional. To ensure safe and effective use, it is important to follow the recommended dosage, inform your doctor about your medical history and any other medicines you are taking, and watch for possible side effects. With proper medical guidance and regular monitoring, the benefits of Lesuride MPS Tablet can be achieved while minimising potential risks to your health.

The best time to take Lesuride MPS Tablet is about 30 minutes before a meal. Taking it before eating helps the medicine work more effectively by improving gut movement and reducing symptoms like bloating, indigestion, and nausea. This timing may also help lower the chances of side effects such as dizziness or drowsiness. Always follow the instructions given by your healthcare provider for the safest and most effective use.

Lesuride MPS Tablet may rarely cause irregular heartbeats, also known as arrhythmias, due to its potential to affect the heart's electrical activity. This phenomenon is more likely to occur in individuals with pre-existing cardiac conditions or those taking concurrent medications that influence heart rhythm. If you experience symptoms such as rapid or irregular heartbeats, lightheadedness, or shortness of breath, seek medical attention promptly. Your healthcare provider may choose to monitor your cardiac function and adjust your treatment plan accordingly to ensure your safety.

Lesuride MPS Tablet contains Levosulpiride, which belongs to a group of medicines called 'prokinetics and antipsychotics.' It works by increasing the pressure in the lower oesophageal sphincter, helping to prevent stomach acid from flowing back into the oesophagus (food pipe) and thereby managing gastroesophageal reflux disease. It also enhances gut motility without disrupting its rhythm, which helps relieve indigestion and improve symptoms of irritable bowel syndrome. Additionally, Lesuride MPS Tablet works by blocking the action of chemical receptors (dopamine) in the brain, helping to improve mood, behaviour, and thoughts in psychotic disorders.

It is generally not recommended to crush or chew Lesuride MPS Tablet , as this can affect the medication's release and absorption in the body. Lesuride MPS Tablet is designed to release the active ingredient in a controlled manner, and crushing or chewing the medication can disrupt this process.

When taking Lesuride MPS Tablet , it's essential to share your medical history, allergies, and current medications with your doctor. Exercise caution if you have pre-existing heart conditions, kidney issues, or epilepsy. Additionally, avoid consuming alcohol and be mindful of potential dizziness or drowsiness that may impact your ability to drive or operate heavy machinery. Regularly monitor your blood pressure and heart rate, and adhere to the recommended dosage. Be vigilant for signs of allergic reactions and consult your doctor if you experience any unusual side effects or worsening symptoms. Finally, schedule regular follow-up appointments with your doctor to ensure a safe and effective treatment journey.

Lesuride MPS Tablet may interact with various medications, including pain killers, anticholinergic drugs, medicines that prolong the QT interval, medicines that cause electrolyte disturbances, narcotics, and aluminium and magnesium-containing antacids. Please note that this is an exhaustive list, and Levosulpiride may interact with other medications not mentioned here. These interactions can lead to adverse effects such as increased risk of side effects, enhanced or prolonged QT interval, electrolyte imbalances, and increased risk of bleeding or bruising. Additionally, interactions may reduce the efficacy of one or both medications. To avoid potential interactions and ensure safe treatment with Levosulpiride, it is essential to inform your doctor about all medications you are currently taking. Your doctor can help you manage potential interactions and adjust your treatment plan accordingly.

Lesuride MPS Tablet is generally well-tolerated, but some individuals may experience common side effects such as dizziness, sleepiness, weakness, and vertigo (spinning sensation). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - LES0043

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